Preparative separation and purification of bufadienolides from Chinese traditional medicine of ChanSu using high-speed counter-current chromatography

Journal of Separation Science

Volumn 33, Issue 9, 2010, Pages 1325-1330

  Li, Jingkui ^a,b   Ma, Xiaochi ^a   Li, Fengyun ^a   Wang, Jingkui ^a   Chen, Huirong ^a   Wang, Gang ^a   Lv, Xia ^a   Sun, Changkai ^a   Jia, Jingming ^b  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Bufadienolide; ChanSu; Counter current chromatography; Separation

Indexed keywords

BUFALIN; CHANSU; CHEMICAL STRUCTURE; CHINESE TRADITIONAL MEDICINE; COUNTERCURRENT CHROMATOGRAPHY; CRUDE EXTRACT; HIGH-SPEED COUNTER CURRENT CHROMATOGRAPHY; ISOLATION AND PURIFICATION; PREPARATIVE SEPARATION AND PURIFICATION; TWO-PHASE SOLVENT SYSTEM;

PURIFICATION;

CHROMATOGRAPHY;

ACETIC ACID ETHYL ESTER; ARENOBUFAGIN; BUFALIN; BUFOTALIN; CHANSU; CINOBUFOTALIN; GAMABUFOTALIN; TELOCINOBUFAGIN; UNCLASSIFIED DRUG; VENOM;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHINESE MEDICINE; CONTROLLED STUDY; COUNTER CURRENT CHROMATOGRAPHY; DRUG PURIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; ELUTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ISOLATION AND PURIFICATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TOAD; TRADITIONAL MEDICINE;

AMPHIBIAN VENOMS; BUFANOLIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUNTERCURRENT DISTRIBUTION; MAGNETIC RESONANCE SPECTROSCOPY; MEDICINE, CHINESE TRADITIONAL;

EID: 77952143827     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200900782     Document Type: Article

References (22)

1. Ma, X. C., Zhang, B. J., Xin, X. L., Huang, S. S., Deng, S., Zhang, H. L., Shu, X. H., Diao, Y. P., Cui, J., Nat. Prod. Commun. 2009, 4, 179-184.
2. National Commission of Chinese Pharmacopoeia. Pharmacopoeia of the People's Republic of China, Chemical Industry Press, Bei Jing 2005, p. 316.
3. Nogawa, T., Kamano, Y., Yamashiita, A., J. Nat. Prod. 2001, 64, 1148-1152.
4. Kamano, Y., Nogawa, T., Yamashita, A., J. Nat. Prod. 2002, 65, 1001-1005.
5. Ma, X. C., Xin, X. L., Liu, K. X., Han, J., Guo, D. A., J. Nat. Prod. 2008, 71, 1268-1270.
6. Masuda, Y., Kawazoe, N., Nakajo, S., Leukemia Res. 1995, 19, 549-556.
7. Kamano, Y., Kotake, A., Hashima, H., Inoue, M., Morita, H., Takeya, K., Pettit, G. P., Bioorg. Med. Chem. 1998, 6, 1504-1507.
8. Yeh, J. Y., Huang, W. J., Kan, S. F., Wang, P. S., Prostate 2003, 54, 112-117.
9. Ye, M., Qu, G., Guo, H. Z., Guo, D. A., J. Steroid Biochem. Mol. Biol. 2004, 91, 87-98.
10. Kamano, Y., Yamashita, A., Nogawa, T., Morita, H., Takeya, K., Itokawa, H., Segawa, T., Yukita, A., Saitiou, K., Katsuyama, M., Pettit, G. R., J. Med. Chem. 2002, 45, 5440-5447.
11. Ito, Y., J. Chromatogr. 1981, 214, 122-124.
12. Ma, C. J., Li, G., Zheng, J., Zheng, Q. S., Fan, X., Wang, Z. H., J. Sep. Sci. 2009, 32, 1949-1956.
13. Qiu, F., Jiang, L., Yao, S., Ma, L., Kong, L. Y., J. Sep. Sci. 2009, 32, 2146-2151.
14. Yang, Y., Huang, Y., Gu, D. Y., Sabir, G., Chromatographia 2009, 69, 963-967.
15. Feng, L., Ji, H. W., Gu, H. X., Wang, D. C., Cui, J. C., Liu, R. M., Zhai, J., Chromatographia 2009, 70, 1197-1200.
16. Tian, G. L., Zhang, Y. B., Zhang, T. Y., Yang, F. Q., Ito, Y., J. Chromatogr. A 2000, 904, 107-111.
17. Oka, H., Harada, K. I., Suzuki, M., Fujii, K., Iwaya, M., Ito, Y., Goto, T., Mastumoto, H., J. Chromatogr. A 2003, 989, 249-255.
18. Ye, M., Guo, H., Guo, H. Z., Han, J., Guo, D. A., J. Chromatogr. B 2006, 838, 86-95.
19. Ma, X. C., Zhang, B. J., Deng, S., Wang, C. Y., Shu, X. H., Huang, S. S., Prog. Mod. Biomed. 2009, 18, 3519-3522.
20. Ye, M., Qu, G. Q., Guo, H. Z., Guo, D. A., J. Steroid Biochem. Mol. Biol. 2004, 91, 87-98.
21. Qiao, L., Duan, W. J., Chen, H., Liu, T., Pei, Y. H., J. Shenyang Pharm. Univ. 2007, 24, 611-614.
22. Ma, X. C., Cui, J., Zheng, J., Guo, D. A., J. Mol. Cata. Enzym. B 2007, 48, 42-50.