Endogenous orexin-A modulates gastric motility by peripheral mechanisms in rats

Peptides

Volumn 31, Issue 6, 2010, Pages 1099-1108

  Bülbül, Mehmet ^a   Tan, Ruken ^a   Gemici, Burcu ^a   Özdem, Sebahat ^a   Üstünel, Ismail ^a   Acar, Nuray ^a   Izgüt Uysal, V Nimet ^a  

^a AKDENIZ UNIVERSITY   (Turkey)

Author keywords

Fasting; Gastric motility; Orexin A; Preproorexin

Indexed keywords

OREXIN 1 RECEPTOR; OREXIN A; PREPROOREXIN; PROTEIN PRECURSOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; HORMONE ACTION; HORMONE BLOOD LEVEL; HORMONE SYNTHESIS; HYPOTHALAMUS; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STOMACH ANTRUM; STOMACH EMPTYING; STOMACH MOTILITY; UPREGULATION;

ANIMALS; BENZOXAZOLES; FASTING; GASTRIC EMPTYING; GASTROINTESTINAL MOTILITY; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; NEUROPEPTIDES; RATS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROPEPTIDE; UP-REGULATION; UREA; VAGUS NERVE;

RATTUS;

EID: 77952107138     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2010.03.007     Document Type: Article

References (55)

1. Ariga H., Imai K., Chen C., Mantyh C., Pappas T.N., and Takahashi T. Fixed feeding potentiates interdigestive gastric motor activity in rats: importance of eating habits for maintaining interdigestive MMC. American Journal of Physiology - Gastrointestinal and Liver Physiology 294 (2008) G655-G659
2. Ariga H., Tsukamoto K., Chen C., Mantyh C., Pappas T.N., and Takahashi T. Endogenous acyl ghrelin is involved in mediating spontaneous phase III-like contractions of the rat stomach. Neurogastroenterology and Motility 19 (2007) 675-680
3. Baccari M.C., and Calamai F. Influence of orexin A on the mechanical activity of mouse gastric strips. Regulatory Peptides 146 (2008) 67-72
4. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72 (1976) 248-254
5. Burks T.F., Galligan J.J., Porreca F., and Barber W.D. Regulation of gastric-emptying. Federation Proceedings 44 (1985) 2897-2901
6. Cai X.J., Widdowson P.S., Harrold J., Wilson S., Buckingham R.E., Arch J.R.S., et al. Hypothalamic orexin expression - modulation by blood glucose and feeding. Diabetes 48 (1999) 2132-2137
7. Chung S.A., Rotstein O., Greenberg G.R., and Diamant N.E. Mechanisms coordinating gastric and small-intestinal mmc - role of extrinsic innervation rather than motilin. American Journal of Physiology - Gastrointestinal and Liver Physiology 30 (1994) G800-G809
8. Corak A., Coskun T., Alican I., Kurtel H., and Yegen B.C. The effect of nitric oxide synthase blockade and indomethacin on gastric emptying and gastric contractility. Pharmacology 54 (1997) 298-304
9. Costa M. All together now: from pacemakers to gastric peristalsis. Journal of Physiology - London 571 (2006) 1
10. Date Y., Ueta Y., Yamashita H., Yamaguchi H., Matsukura S., Kangawa K., et al. Orexins, orexigenic hypothalamic peptides, interact with autonomic, neuroendocrine and neuroregulatory systems. Proceedings of the National Academy of Sciences of the United States of America 96 (1999) 748-753
11. de Lecea L., and Sutcliffe J.G. The hypocretins/orexins: novel hypothalamic neuropeptides involved in different physiological systems. Cellular and Molecular Life Sciences 56 (1999) 473-480
12. Dube M.G., Horvath T.L., Kalra P.S., and Kalra S.P. Evidence of NPY Y5 receptor involvement in food intake elicited by orexin A in sated rats. Peptides 21 (2000) 1557-1560
13. Ehrstrom M., Gustafsson T., Finn A., Kirchgessner A., Gryback P., Jacobsson H., et al. Inhibitory effect of exogenous orexin a on gastric emptying, plasma leptin, and the distribution of orexin and orexin receptors in the gut and pancreas in man. Journal of Clinical Endocrinology & Metabolism 90 (2005) 2370-2377
14. Ehrstrom M., Levin F., Kirchgessner A.L., Schmidt P.T., Hilsted L.M., Gryback P., et al. Stimulatory effect of endogenous orexin A on gastric emptying and acid secretion independent of gastrin. Regulatory Peptides 132 (2005) 9-16
15. Ehrstrom M., Naslund E., Ma J., Kirchgessner A.L., and Hellstrom P.M. Physiological regulation and NO-dependent inhibition of migrating myoelectric complex in the rat small bowel by OXA. American Journal of Physiology - Gastrointestinal and Liver Physiology 285 (2003) G688-G695
16. Fujino K., Inui A., Asakawa A., Kihara N., Fujimura M., and Fujimiya M. Ghrelin induces fasted motor activity of the gastrointestinal tract in conscious fed rats. The Journal of Physiology 550 (2003) 227-240
17. Furudono Y., Ando C., Yamamoto C., Kobashi M., and Yamamoto T. Involvement of specific orexigenic neuropeptides in sweetener-induced overconsumption in rats. Behavioural Brain Research 175 (2006) 241-248
18. Grabauskas G., and Moises H.C. Gastrointestinal-projecting neurones in the dorsal motor nucleus of the vagus exhibit direct and viscerotopically organized sensitivity to orexin. The Journal of Physiology 549 (2003) 37-56
19. Hansen M.B. Small intestinal manometry. Physiological Research 51 (2002) 541-556
20. Hasselbalch S.G., Knudsen G.M., Jakobsen J., Hageman L.P., Holm S., and Paulson O.B. Blood-brain barrier permeability of glucose and ketone bodies during short-term starvation in humans. American Journal of Physiology 268 (1995) E1161-E1166
21. Heinonen M.V., Purhonen A.K., Makela K.A., and Herzig K.H. Functions of orexins in peripheral tissues. Acta Physiologica (Oxford) 192 (2008) 471-485
22. Hellstrom P.M., and Ljung T. Nitrergic inhibition of migrating myoelectric complex in the rat is mediated by vasoactive intestinal peptide. Neurogastroenterology and Motility 8 (1996) 299-306
23. Johren O., Neidert S.J., Kummer M., Dendorfer A., and Dominiak P. Prepro-orexin and orexin receptor mRNAs are differentially expressed in peripheral tissues of male and female rats. Endocrinology 142 (2001) 3324-3331
24. Kappeler L., Zizzari P., Grouselle D., Epelbaum J., and Bluet-Pajot M.T. Plasma and hypothalamic peptide-hormone levels regulating somatotroph function and energy balance in fed and fasted states: a comparative study in four strains of rats. Journal of Neuroendocrinology 16 (2004) 980-988
25. Kihara N., Fujimura M., Yamamoto I., Itoh E., Inui A., and Fujimiya M. Effects of central and peripheral urocortin on fed and fasted gastroduodenal motor activity in conscious rats. American Journal of Physiology - Gastrointestinal and Liver Physiology 280 (2001) G406-G419
26. Kirchgessner A.L. Orexins in the brain-gut axis. Endocrine Reviews 23 (2002) 1-15
27. Kirchgessner A.L., and Liu M. Orexin synthesis and response in the gut. Neuron 24 (1999) 941-951
28. Kobashi M., Furudono Y., Matsuo R., and Yamamoto T. Central orexin facilitates gastric relaxation and contractility in rats. Neuroscience Letters 332 (2002) 171-174
29. Komaki G., Matsumoto Y., Nishikata H., Kawai K., Nozaki T., Takii M., et al. Orexin-A and leptin change inversely in fasting non-obese subjects. European Journal of Endocrinology 144 (2001) 645-651
30. Korczynski W., Ceregrzyn M., Matyjek R., Kato I., Kuwahara A., Wolinski J., et al. Central and local (enteric) action of orexins. Journal of Physiology and Pharmacology 57 Suppl. 6 (2006) 17-42
31. Krowicki Z.K., Burmeister M.A., Berthoud H.R., Scullion R.T., Fuchs K., and Hornby P.J. Orexins in rat dorsal motor nucleus of the vagus potently stimulate gastric motor function. American Journal of Physiology - Gastrointestinal and Liver Physiology 283 (2002) G465-G472
32. Kukkonen J.P., Holmqvist T., Ammoun S., and Akerman K.E. Functions of the orexinergic/hypocretinergic system. American Journal of Physiology - Cell Physiology 283 (2002) C1567-C1591
33. Ljung T., and Hellstrom P.M. Vasoactive intestinal peptide suppresses migrating myoelectric complex of rat small intestine independent of nitric oxide. Acta Physiologica Scandinavica 165 (1999) 225-231
34. Mondal M.S., Nakazato M., Date Y., Murakami N., Yanagisawa M., and Matsukura S. Widespread distribution of orexin in rat brain and its regulation upon fasting. Biochemical and Biophysical Research Communications 256 (1999) 495-499
35. Nakabayashi M., Suzuki T., Takahashi K., Totsune K., Muramatsu Y., Kaneko C., et al. Orexin-A expression in human peripheral tissues. Molecular and Cellular Endocrinology 205 (2003) 43-50
36. Nakade Y., Tsukamoto K., Pappas T.N., and Takahashi T. Central glucagon like peptide-1 delays solid gastric emptying via central CRF and peripheral sympathetic pathway in rats. Brain Research 1111 (2006) 117-121
37. Naslund E., Ehrstrom M., Ma J., Hellstrom P.M., and Kirchgessner A.L. Localization and effects of orexin on fasting motility in the rat duodenum. American Journal of Physiology - Gastrointestinal and Liver Physiology 282 (2002) G470-G479
38. Novak C.M., Jiang X.L., Wang C.F., Teske J.A., Kotz C.M., and Levine J.A. Caloric restriction and physical activity in zebrafish (Danio rerio). Neuroscience Letters 383 (2005) 99-104
39. Okumura T., Takeuchi S., Motomura W., Yamada H., Egashira S., Asahi S., et al. Requirement of intact disulfide bonds in orexin-A-induced stimulation of gastric acid secretion that is mediated by OX1 receptor activation. Biochemical and Biophysical Research Communications 280 (2001) 976-981
40. Ouedraogo R., Naslund E., and Kirchgessner A.L. Glucose regulates the release of orexin-A from the endocrine pancreas. Diabetes 52 (2003) 111-117
41. Park E.S., Yi S.J., Kim J.S., Lee H.S., Lee I.S., Seong J.K., et al. Changes in orexin-A and neuropeptide Y expression in the hypothalamus of the fasted and high-fat diet fed rats. Journal of Veterinary Science 5 (2004) 295-302
42. Rodriguezmembrilla A., Martinez V., Jimenez M., Gonalons E., and Vergara P. Is nitric-oxide the final mediator regulating the migrating myoelectric complex cycle. American Journal of Physiology - Gastrointestinal and Liver Physiology 31 (1995) G207-G214
43. Sakurai T., Amemiya A., Ishii M., Matsuzaki I., Chemelli R.M., Tanaka H., et al. Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior. Cell 92 (1998) 1 page following 696
44. Samson W.K., and Resch Z.T. The hypocretin/orexin story. Trends in Endocrinology and Metabolism 11 (2000) 257-262
45. Satoh Y., Takeuchi T., Yamazaki Y., Okishio Y., Nishio H., Takatsuji K., et al. Mediators of nonadrenergic, noncholinergic relaxation in longitudinal muscle of the intestine of ICR mice. Journal of Smooth Muscle Research 35 (1999) 65-75
46. Smart D., Jerman J.C., Brough S.J., Rushton S.L., Murdock P.R., Jewitt F., et al. Characterization of recombinant human orexin receptor pharmacology in a Chinese hamster ovary cell-line using FLIPR. British Journal of Pharmacology 128 (1999) 1-3
47. Tache Y., Maedahagiwara M., and Turkelson C.M. Central-nervous-system action of corticotropin-releasing factor to inhibit gastric-emptying in rats. American Journal of Physiology 253 (1987) G241-G245
48. Takahashi N., Okumura T., Yamada H., and Kohgo Y. Stimulation of gastric acid secretion by centrally administered orexin-A in conscious rats. Biochemical and Biophysical Research Communications 254 (1999) 623-627
49. Takahashi T. Pathophysiological significance of neuronal nitric oxide synthase in the gastrointestinal tract. Journal of Gastroenterology 38 (2003) 421-430
50. Tanabe Y., Calland J.F., and Schirmer B.D. Effects of peritoneal injury and endotoxin on myoelectric activity and transit. Journal of Surgical Research 116 (2004) 330-336
51. Tanaka T., VanKlompenberg L.H., and Sarr M.G. Selective role of vagal and nonvagal innervation in initiation and coordination of gastric and small bowel patterns of interdigestive and postprandial motility. Journal of Gastrointestinal Surgery 5 (2001) 418-433
52. Tomita R., Tanjoh K., Fujisaki S., and Fukuzawa M. The role of nitric oxide (NO) in the human pyloric sphincter. Hepato-Gastroenterology 46 (1999) 2999-3003
53. Tritos N.A., Mastaitis J.W., Kokkotou E., and Maratos-Flier E. Characterization of melanin concentrating hormone and preproorexin expression in the murine hypothalamus. Brain Research 895 (2001) 160-166
54. Wolf G. Orexins: a newly discovered family of hypothalamic regulators of food intake. Nutrition Reviews 56 (1998) 172-173
55. Zheng J., Ariga H., Taniguchi H., Ludwig K., and Takahashi T. Ghrelin regulates gastric phase III-like contractions in freely moving conscious mice. Neurogastroenterology and Motility 21 (2009) 78-84