Toxicities of topical ophthalmic anesthetics

Expert Opinion on Drug Safety

Volumn 6, Issue 6, 2007, Pages 637-640

  McGee, Hall T ^a   Fraunfelder, F W ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Antiemetics; Drug safety; Nausea and vomiting of pregnancy; NVP; Teratogenicity

Indexed keywords

AMFENAC; ANESTHETIC AGENT; BENZALKONIUM CHLORIDE; BENZOIC ACID; BROMFENAC; CHLORBUTOL; COCAINE; DICLOFENAC; KETOROLAC; LIDOCAINE; METHYL PARABEN; OXYBUPROCAINE; PROPYL PARABEN; PROXYMETACAINE; TETRACAINE; LOCAL ANESTHETIC AGENT;

ACANTHAMOEBA KERATITIS; ANXIETY; BRAIN HEMORRHAGE; CLOSED ANGLE GLAUCOMA; CORNEA INJURY; CORNEA PERFORATION; CORNEA ULCER; CYTOTOXICITY; DRUG ABUSE; DRUG EFFICACY; DRUG MECHANISM; DRUG SAFETY; DRUG TOLERABILITY; DRY EYE; DYSPNEA; ENDOPHTHALMITIS; EYE DISCOMFORT; EYE DISEASE; EYE INFECTION; EYE INJURY; EYE PAIN; EYE SURGERY; EYE TOXICITY; HEART ARRHYTHMIA; HUMAN; HYPERSENSITIVITY; HYPERTENSION; KERATOPATHY; LOCAL ANESTHESIA; MYDRIASIS; OPHTHALMOLOGY; REVIEW; SEIZURE; SIDE EFFECT; SKIN ALLERGY; TOPICAL ANESTHESIA; UVEITIS; ANIMAL;

ANESTHETICS, LOCAL; ANIMALS; HUMANS; LIDOCAINE; OPHTHALMOLOGIC SURGICAL PROCEDURES; TETRACAINE;

EID: 38449088947     PISSN: 14740338     EISSN: None     Source Type: Journal    
DOI: 10.1517/14740338.6.6.637     Document Type: Review

References (23)

1. CALATAYUD J, GONZALES A: History of the development and evolution of local anesthesia since the coca leaf. Anesthesiology (2003) 98:1503-1508.
2. ELLIS FD: Topical and local anesthetic agents. In: Textbook of Ocular Pbarmacology. Zimmerman TJ (Ed.), Lippincott-Raven, Philadelphia, USA (1997):791-793.
3. BARTFIELD JM, HOLMES TJ, RACCIO-ROBAK N: A comparison of proparacaine and tetracaine eye anesthetics. Acad. Emerg. Med. (1994) 1:364-367.
4. BURNS RP: Toxic effects of local anesthetics. JAMA (1978) 240:347.
5. RAPUANO CJ: Topical anesthetic abuse: a case report of bilateral corneal ring infiltrates. J. Qphthalmic Nurs. Technol. (1990) 9:94-95.
6. MEYERS-ELLIOTT RH, PETTIT TH, MAXWELL WA: Viral antigens in the immune ring of Herpes simplex stromal keratitis. Arch. Ophthalmol. (1980) 98:897-901.
7. ROSENWASSER GO, HOLLAND S, PFLUGFELDER SC et al.: Topical anesthetic abuse. Ophthalmology (1990) 97:967-972.
8. CHERN KC, MEISLER DM, WILHELMUS KR, JONES DB, STERN GA, LOWDER CY. Corneal anesthetic abuse and Candida keratitis. Ophthalmology (1996) 103:37-40.
9. KINTNER JC, GROSSNIKLAUS HE, LASS JH, JACOBS G: Infectious crystalline keratopathy associated with topical anesthetic abuse. Cornea (1990) 1:77-80.
10. MOREIRA LB, KASETSUWAN N, SANCHEZ D, SHAH SS, LABREE L, MCDONNELL PJ: Toxicity of topical anesthetic agents to human keratocytes in vivo. J. Cataract Refract. Surg. (1999) 25:975-980.
11. RISCO JM, MILLAR LC: Ultrastructural alterations in the endodielium in a patient with topical anesthetic abuse keratopathy. Ophthalmology (1992) 99:628-633.
12. CHEN HT, CHEN KH, HSU WM: Toxic keratopathy associated with abuse of low-dose anesthetic: a case report. Cornea (2004) 23:527-529.
13. JALLET G, CLEIRENS S, GIRARD E, BECHETOILLE A. Particularly rapid appearance of a severe toxic keratopathy caused by oxybupfocaine. [French]. Bull. Soc. Ophtalmol. France (1980) 80:385-387.
14. HADDAD R: Fibrinous iritis due to oxybuprocaine. Br. J. Ophthalmol. (1989) 73:76-77.
15. FRAUNFELDER FT. FRAUNFELDER FW. Topical local anesthetics. In: Drug-Induced Ocular Side Effects. (5th Edition). Fraunfelder FT, Fraunfelder FW (Eds), Butterworth Heinemann, Boston, USA (2000):615-619.
16. LIESEGANG TJ, PERNICIARO C: Fingertip dermatitis in an ophthalmologist caused by proparacaine. Am. J. Ophthalmol. (1999) 127:240-241.
17. DANNAKER CJ, MAIBACH HI, AUSTIN E: Allergic contact dermatitis to proparacaine with subsequent cross-sensitization to tetracaine from ophthalmic preparations. Am. J. Contact Dermat. (2001) 12:177-179.
18. MILLER JJ, SCOTT IU, FLYNN HW Jr, SMIDDY WE, NEWTON J, MILLER D: Acute-onset endophthalmitis after cataract surgery (2000-2004): incidence, clinical settings, and visual acuity outcomes after treatment. Am. J. Ophthalmol. (2005) 139:983-987.
19. KARP CL, COX TA, WAGONER MD, ARIYASU RG, JACOBS DS: Intracameral anesthesia: a report by the American academy of ophthalmology. Ophthalmology (2001) 108:1704-1710.
20. MCHENRY JG, ZEITER JH, MADISON MP, SPOOR TC: Ophthalmic complications of crack cocaine. Ophthalmology (1993) 100:1747.
21. MILLICHAMP NJ: Toxicity in specific ocular tissues: corneal epithelial defects and erosions. In: Ophthalmic Toxicology. Chiou GCY (Ed.), Taylor and Francis Publishing, Philadelphia, USA (1999):49.
22. ELEFTHERIADIS H, CHEONG M, SANDEMAN S et al.: Corneal toxicity secondary to inadvertent use of benzalkonium chloride preserved viscoelastic material in cataract surgery. Br. J. Ophthalmol. (2002) 86:299-305.
23. CHIOU GCY. Ophthalmic toxicity by local agents: preservatives. In: Ophthalmic Toxicology. Chiou GCY (Ed.), Taylor and Francis Publishing, Philadelphia, USA (1999):302.