MT2 melatonin receptor immunoreactivity in neurons is very high in the aged hippocampal formation in gerbils

Cellular and Molecular Neurobiology

Volumn 30, Issue 2, 2010, Pages 255-263

  Lee, Choong Hyun ^a   Choi, Jung Hoon ^a   Yoo, Ki Yeon ^a   Park, Ok Kyu ^a   Hwang, In Koo ^b   You, Sang Guan ^c   Lee, Boo Yong ^d   Kang, Il Jun ^a   Won, Moo Ho ^a  

^a Hallym University   (South Korea)

^b Seoul National University   (South Korea)

^c Gangneung Wonju National University   (South Korea)

^d CHA University   (South Korea)

Author keywords

Aging; Gerbil; Hippocampus; Melatonin receptor; MT2

Indexed keywords

MELATONIN 2 RECEPTOR; MELATONIN;

AGE; AGED; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN REGION; CONTROLLED STUDY; DENTATE GYRUS; HIGH RISK POPULATION; HIPPOCAMPUS; IMMUNOCOMPETENT CELL; IMMUNODETECTION; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; NONHUMAN; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PYRAMIDAL NERVE CELL; RAT; WESTERN BLOTTING; AGING; ANIMAL; CYTOLOGY; GERBIL; METABOLISM; NERVE CELL; PHYSIOLOGY;

AGING; ANIMALS; GERBILLINAE; HIPPOCAMPUS; MALE; MELATONIN; NEURONS; RECEPTOR, MELATONIN, MT2;

GERBILLINAE;

EID: 77952091231     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-009-9447-6     Document Type: Article

References (39)

1. BN Ames MK Shigenaga TM Hagen 1993 Oxidants, antioxidants, and the degenerative diseases of aging Proc Natl Acad Sci USA 90 7915 7922 10.1073/pnas.90.17.7915 1:CAS:528:DyaK3sXmtVSksL4%3D 8367443
2. J Arendt 1998 Melatonin and the pineal gland: influence on mammalian seasonal and circadian physiology Rev Reprod 3 13 22 10.1530/ror.0.0030013 1:CAS:528:DyaK1cXht1WrsLY%3D 9509985 (Pubitemid 28062305)
3. J Bustamante A Czerniczyniec C Cymeryng S Lores-Arzaiz 2008 Age related changes from youth to adulthood in rat brain cortex: nitric oxide synthase and mitochondrial respiratory function Neurochem Res 33 1216 1223 10.1007/s11064-007-9570-z 1:CAS:528:DC%2BD1cXmsVartrc%3D 18259860
4. P Carampin S Rosan D Dalzoppo G Zagotto P Zatta 2003 Some biochemical properties of melatonin and the characterization of a relevant metabolite arising from its interaction with H2O2 J Pineal Res 34 134 142 10.1034/j.1600-079X.2003.00020.x 1:CAS:528:DC%2BD3sXhvVOmt7s%3D 12562505 (Pubitemid 36255922)
5. D Dori G Casale SB Solerte M Fioravanti G Migliorati G Cuzzoni E Ferrari 1994 Chrono-neuroendocrinological aspects of physiological aging and senile dementia Chronobiologia 21 121 126 1:STN:280:DyaK2M%2FgvFWgtw%3D%3D 7924632
6. ML Dubocovich 1995 Melatonin receptors: are there multiple subtypes? Trends Pharmacol Sci 16 50 56 10.1016/S0165-6147(00)88978-6 1:CAS:528: DyaK2MXkvVejt78%3D 7762083
7. ML Dubocovich M Markowska 2005 Functional MT1 and MT2 melatonin receptors in mammals Endocrine 27 101 110 10.1385/ENDO:27:2:101 1:CAS:528: DC%2BD2MXhtFansLjE 16217123 (Pubitemid 41558442)
8. ML Dubocovich MI Masana S Benloucif 1999 Molecular pharmacology and function of melatonin receptor subtypes Adv Exp Med Biol 460 181 190 10.1007/0-306-46814-X-20 1:CAS:528:DC%2BD3cXltV2qtbg%3D 10810513
9. E Ferrari F Magri D Dori G Migliorati T Nescis G Molla M Fioravanti SB Solerte 1995 Neuroendocrine correlates of the aging brain in humans Neuroendocrinology 61 464 470 10.1159/000126869 1:CAS:528:DyaK2MXltF2qtr4%3D 7783860
10. E Ferrari A Arcaini R Gornati L Pelanconi L Cravello M Fioravanti SB Solerte F Magri 2000 Pineal and pituitary-adrenocortical function in physiological aging and in senile dementia Exp Gerontol 35 1239 1250 10.1016/S0531-5565(00)00160-1 1:CAS:528:DC%2BD3cXoslGgurk%3D 11113605
11. MJ Gerdin MI Masana MA Rivera-Bermúdez RL Hudson DJ Earnest MU Gillette ML Dubocovich 2004 Melatonin desensitizes endogenous MT2 melatonin receptors in the rat suprachiasmatic nucleus: relevance for defining the periods of sensitivity of the mammalian circadian clock to melatonin FASEB J 18 1646 1656 10.1096/fj.03-1339com 1:CAS:528:DC%2BD2cXpslGku74%3D 15522910 (Pubitemid 39463704)
12. MV Hogan Y El-Sherif A Wieraszko 2001 The modulation of neuronal activity by melatonin: in vitro studies on mouse hippocampal slices J Pineal Res 30 87 96 10.1034/j.1600-079X.2001.300204.x 1:CAS:528:DC%2BD3MXhs1Shtb8%3D 11270484 (Pubitemid 32176211)
13. CR Jack Jr RC Petersen Y Xu PC O'Brien GE Smith RJ Ivnik BF Boeve EG Tangalos E Kokmen 2000 Rates of hippocampal atrophy correlate with change in clinical status in aging and AD Neurology 55 484 489 10953178
14. M Karasek 2004 Melatonin, human aging, and age-related diseases Exp Gerontol 39 1723 1729 10.1016/j.exger.2004.04.012 1:CAS:528:DC%2BD2cXhtVCltLfP 15582288 (Pubitemid 39576142)
15. TS King BA Richardson RJ Reiter 1981 Age-associated changes in pineal serotonin N-acetyltransferase activity and melatonin content in the male gerbil Endocr Res Commun 8 253 262 10.3109/07435808109045744 1:CAS:528: DyaL38XhvFerur8%3D 7338213
16. MG Knuttinen AE Gamelli C Weiss JM Power JF Disterhoft 2001 Age-related effects on eyeblink conditioning in the F344 × BN F1 hybrid rat Neurobiol Aging 22 1 8 10.1016/S0197-4580(00)00194-9 1:STN:280:DC%2BD3MzgtVGgtQ%3D%3D 11164270 (Pubitemid 32332992)
17. M Kotler C Rodriguez RM Sáinz I Antolín A Menéndez-Peláez 1998 Melatonin increases gene expression for antioxidant enzymes in rat brain cortex J Pineal Res 24 83 89 10.1111/j.1600-079X.1998.tb00371.x 1:CAS:528:DyaK1cXptlOnsw%3D%3D 9510432 (Pubitemid 28168319)
18. CP LeBel SC Bondy 1992 Oxidative damage and cerebral aging Prog Neurobiol 38 601 609 10.1016/0301-0082(92)90043-E 1:CAS:528:DyaK38XktVCltbc%3D 1589582
19. D Leger M Laudon N Zisapel 2004 Nocturnal 6-sulfatoxymelatonin excretion in insomnia and its relation to the response to melatonin replacement therapy Am J Med 116 91 95 10.1016/j.amjmed.2003.07.017 1:CAS:528:DC%2BD2cXjtFektQ%3D%3D 14715322 (Pubitemid 38056661)
20. J Liu H Atamna H Kuratsune BN Ames 2002 Delaying brain mitochondrial decay and aging with mitochondrial antioxidants and metabolites Ann N Y Acad Sci 959 133 166 1:CAS:528:DC%2BD38XktFWqur4%3D 11976193
21. Loskota WA, Lomax P, Verity MA (1974) A stereotaxic atlas of the Mongolian Gerbil brain (Meriones unguiculatus). Ann Arbor Science Publishers Inc, Michigan, pp 70-79
22. F Magri M Locatelli G Balza G Molla G Cuzzoni M Fioravanti SB Solerte E Ferrari 1997 Changes in endocrine circadian rhythms as markers of physiological and pathological brain aging Chronobiol Int 14 385 396 10.3109/07420529709001459 1:CAS:528:DyaK2sXlvFelu70%3D 9262874
23. U Musshoff D Riewenherm E Berger JD Fauteck EJ Speckmann 2002 Melatonin receptors in rat hippocampus: molecular and functional investigations Hippocampus 12 165 173 10.1002/hipo.1105 1:CAS:528:DC%2BD38XjsVCks74%3D 12000116 (Pubitemid 34436701)
24. SL Payão CV de Carvalho ER da Silva C Lopes RP Markus LM Winter MA Smith 2001 Pinealectomy-associated decrease in ribosomal gene activity in rats Biogerontology 2 105 108 10.1023/A:1011541302289 11708375 (Pubitemid 32780860)
25. RC Petersen CR Jack Jr YC Xu SC Waring PC O'Brien GE Smith RJ Ivnik EG Tangalos BF Boeve E Kokmen 2000 Memory and MRI-based hippocampal volumes in aging and AD Neurology 54 581 587 1:STN:280:DC%2BD3c7kt12kuw%3D%3D 10680786
26. W Pierpaoli 1998 Neuroimmunomodulation of aging. A program in the pineal gland Ann N Y Acad Sci 840 491 497 10.1111/j.1749-6632.1998.tb09587.x 1:CAS:528:DyaK1cXktFSgs7o%3D 9629275 (Pubitemid 28302074)
27. RJ Reiter BA Richardson LY Johnson BN Ferguson DT Dinh 1980 Pineal melatonin rhythm: reduction in aging Syrian hamsters Science 210 1372 1373 10.1126/science.7434032 1:CAS:528:DyaL3MXksVOrsA%3D%3D 7434032
28. RJ Reiter D Tan SJ Kim LC Manchester W Qi JJ Garcia JC Cabrera G El-Sokkary V Rouvier-Garay 1999 Augmentation of indices of oxidative damage in life-long melatonin-deficient rats Mech Ageing Dev 110 157 173 10.1016/S0047-6374(99)00058-5 1:CAS:528:DyaK1MXmsFejsLg%3D 10576246 (Pubitemid 29486734)
29. RJ Reiter DX Tan C Osuna E Gitto 2000 Actions of melatonin in the reduction of oxidative stress. A review J Biomed Sci 7 444 458 10.1007/BF02253360 1:CAS:528:DC%2BD3cXos1yjtb0%3D 11060493
30. SM Reppert C Godson CD Mahle DR Weaver SA Slaugenhaupt JF Gusella 1995 Molecular characterization of a second melatonin receptor expressed in human retina and brain: the Mel1b melatonin receptor Proc Natl Acad Sci USA 92 8734 8738 10.1073/pnas.92.19.8734 1:CAS:528:DyaK2MXotVGqsrk%3D 7568007
31. M Sánchez-Hidalgo JM Guerrero Montávez P Carrascosa-Salmoral Mdel C Naranjo Gutierrez Mdel PJ Lardone CA a Romero 2009 Decreased MT1 and MT2 melatonin receptor expression in extrapineal tissues of the rat during physiological aging J Pineal Res 46 29 35 10.1111/j.1600-079X. 2008.00604.x 18513209
32. E Savaskan MA Ayoub R Ravid D Angeloni F Fraschini F Meier A Eckert F Müller-Spahn R Jockers 2005 Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease J Pineal Res 38 10 16 10.1111/j.1600-079X. 2004.00169.x 1:CAS:528:DC%2BD2MXpsFekuw%3D%3D 15617532 (Pubitemid 40139305)
33. I Schmerold H Niedermüller 2001 Levels of 8-hydroxy-2'- deoxyguanosine in cellular DNA from 12 tissues of young and old Sprague-Dawley rats Exp Gerontol 36 1375 1386 10.1016/S0531-5565(01)00103-6 1:CAS:528:DC%2BD3MXls1ehs7g%3D 11602211 (Pubitemid 32707874)
34. LR Squire 1992 Memory and the hippocampus: a synthesis from findings with rats, monkeys, and humans Psychol Rev 99 195 231 10.1037/0033-295X.99.2.195 1:STN:280:DyaK383nvFClsg%3D%3D 1594723
35. Y Touitou 2001 Human aging and melatonin. Clinical relevance Exp Gerontol 36 1083 1100 10.1016/S0531-5565(01)00120-6 1:CAS:528:DC%2BD3MXkt1yitL4%3D 11404053 (Pubitemid 32515222)
36. Y Touitou A Reinberg A Bogdan A Auzéby H Beck C Touitou 1986 Age-related changes in both circadian and seasonal rhythms of rectal temperature with special reference to senile dementia of Alzheimer type Gerontology 32 110 118 10.1159/000212774 1:STN:280:DyaL283itFOgsg%3D%3D 3710170
37. BR Troen 2003 The biology of aging Mt Sinai J Med 70 3 22 12516005
38. Q Wan HY Man F Liu J Braunton HB Niznik SF Pang GM Brown YT Wang 1999 Differential modulation of GABAA receptor function by Mel1a and Mel1b receptors Nat Neurosci 2 401 403 10.1038/8062 1:CAS:528:DyaK1MXivVyls78%3D 10321240 (Pubitemid 30491246)
39. YH Wei HC Lee 2002 Oxidative stress, mitochondrial DNA mutation, and impairment of antioxidant enzymes in aging Exp Biol Med 227 671 682 1:CAS:528:DC%2BD38XntlyqsLw%3D (Maywood)