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Volumn 29, Issue 1, 2010, Pages 50-58

Neuropathy in a rat model of mild diabetes induced by multiple low doses of streptozotocin: Effects of the antioxidant stobadine in comparison with a high-dose α-lipoic acid treatment

Author keywords

lipoic acid; Diabetes; Neuropathy; Oxidative stress; Stobadine

Indexed keywords

STOBADINE; STREPTOZOCIN; THIOCTIC ACID;

EID: 77952084858     PISSN: 02315882     EISSN: None     Source Type: Journal    
DOI: 10.4149/gpb_2010_01_50     Document Type: Article
Times cited : (18)

References (71)
  • 1
    • 0029915468 scopus 로고    scopus 로고
    • Contraction and relaxation of aortas from diabetic rats: Effects of chronic antioxidant and aminoguanidine treatments
    • doi:10.1007/BF00169180
    • Archibald V., Cotter M. A., Keegan A., Cameron N. E. (1996): Contraction and relaxation of aortas from diabetic rats: effects of chronic antioxidant and aminoguanidine treatments. Naunyn Schmiedebergs. Arch. Pharmacol. 353, 584-591; doi:10.1007/BF00169180
    • (1996) Naunyn Schmiedebergs. Arch. Pharmacol. , vol.353 , pp. 584-591
    • Archibald, V.1    Cotter, M.A.2    Keegan, A.3    Cameron, N.E.4
  • 2
    • 33644541155 scopus 로고    scopus 로고
    • Prolonged ischemic conduction failure after reperfusion in diabetic nerve
    • doi:10.1002/mus.20474
    • Baba M., Nukada H., McMorran D., Takahashi K., Wada R., Yagihashi S. (2006): Prolonged ischemic conduction failure after reperfusion in diabetic nerve. Muscle Nerve 33, 350-355; doi:10.1002/mus.20474
    • (2006) Muscle Nerve , vol.33 , pp. 350-355
    • Baba, M.1    Nukada, H.2    McMorran, D.3    Takahashi, K.4    Wada, R.5    Yagihashi, S.6
  • 3
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • doi:10.2337/diabetes.40.4.405
    • Baynes J. W. (1991): Role of oxidative stress in development of complications in diabetes. Diabetes 40, 405-412; doi:10.2337/diabetes.40.4.405
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 4
    • 0034659178 scopus 로고    scopus 로고
    • Glycoxidation and lipoxidation in atherogenesis
    • doi: 10.1016/S0891-5849(00)00228-8
    • Baynes J. W., Thorpe S. R. (2000): Glycoxidation and lipoxidation in atherogenesis. Free Radic. Biol. Med. 28, 1708-1716; doi: 10.1016/S0891-5849(00) 00228-8
    • (2000) Free Radic. Biol. Med. , vol.28 , pp. 1708-1716
    • Baynes, J.W.1    Thorpe, S.R.2
  • 5
    • 0025189864 scopus 로고
    • Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide
    • doi: 10.1073/pnas.87.4.1620
    • Beckman J. S., Beckman T. W., Chen J., Marshall P. A., Freeman B. A. (1990): Apparent hydroxyl radical production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc. Natl. Acad. Sci. U.S.A. 87, 1620-1624; doi: 10.1073/pnas.87.4.1620
    • (1990) Proc. Natl. Acad. Sci. U.S.A. , vol.87 , pp. 1620-1624
    • Beckman, J.S.1    Beckman, T.W.2    Chen, J.3    Marshall, P.A.4    Freeman, B.A.5
  • 6
    • 0030760940 scopus 로고    scopus 로고
    • Bimoclomol (BRLP-42) ameliorates peripheral neuropathy in streptozotocin-induced diabetic rats
    • doi: 10.1016/S0361-9230(97)00118-4
    • Bíró K., Jednákovits A., Kukorelli T., Hegedüs E., Korányi L. (1997): Bimoclomol (BRLP-42) ameliorates peripheral neuropathy in streptozotocin-induced diabetic rats. Brain Res. Bull. 44, 259-263; doi: 10.1016/S0361-9230(97)00118-4
    • (1997) Brain Res. Bull. , vol.44 , pp. 259-263
    • Bíró, K.1    Jednákovits, A.2    Kukorelli, T.3    Hegedüs, E.4    Korányi, L.5
  • 7
    • 40349087464 scopus 로고    scopus 로고
    • Diabetic microangiopathy: Physiopathological, clinical and therapeutic aspects
    • Camera A., Hopps.E., Caimi G. (2007): Diabetic microangiopathy: physiopathological, clinical and therapeutic aspects. Minerva Endocrinol. 32, 209-229
    • (2007) Minerva Endocrinol. , vol.32 , pp. 209-229
    • Camera, A.1    Hopps, E.2    Caimi, G.3
  • 8
    • 0025905236 scopus 로고
    • Essential fatty acid diet supplementation. Effects on peripheral nerve and skeletal muscle function and capillarization in streptozocin-induced diabetic rats
    • doi:10.2337/diabetes.40.5.532
    • Cameron N. E., Cotter M. A., Robertson S. (1991): Essential fatty acid diet supplementation. Effects on peripheral nerve and skeletal muscle function and capillarization in streptozocin-induced diabetic rats. Diabetes 40, 532-539; doi:10.2337/diabetes.40.5.532
    • (1991) Diabetes , vol.40 , pp. 532-539
    • Cameron, N.E.1    Cotter, M.A.2    Robertson, S.3
  • 9
    • 0026728117 scopus 로고
    • Effects of aminoguanidine on peripheral nerve function and polyol pathway metabolites in streptozotocin-diabetic rats
    • doi:10.1007/BF00401423
    • Cameron N. E., Cotter M. A., Dines K., Love A. (1992): Effects of aminoguanidine on peripheral nerve function and polyol pathway metabolites in streptozotocin-diabetic rats. Diabetologia 35, 946-950; doi:10.1007/BF00401423
    • (1992) Diabetologia , vol.35 , pp. 946-950
    • Cameron, N.E.1    Cotter, M.A.2    Dines, K.3    Love, A.4
  • 10
    • 0027193749 scopus 로고
    • Pharmacological manipulation of vascular endothelium in non-diabetic and streptozotocin-diabetic rats: Effects on nerve conduction, hypoxic resistance and endoneurial capillarization
    • doi:10.1007/BF02743267
    • Cameron N. E., Cotter M. A., Dines K. C., Maxfield E. K. (1993): Pharmacological manipulation of vascular endothelium in non-diabetic and streptozotocin-diabetic rats: effects on nerve conduction, hypoxic resistance and endoneurial capillarization. Diabetologia 36, 516-522; doi:10.1007/ BF02743267
    • (1993) Diabetologia , vol.36 , pp. 516-522
    • Cameron, N.E.1    Cotter, M.A.2    Dines, K.C.3    Maxfield, E.K.4
  • 11
    • 0028567531 scopus 로고
    • Effects of evening primrose oil treatment on sciatic nerve blood flow and endoneural oxygen tension in streptozotocin-diabetic rats
    • doi: 10.1007/BF00571955
    • Cameron N. E., Cotter M. A. (1994): Effects of evening primrose oil treatment on sciatic nerve blood flow and endoneural oxygen tension in streptozotocin-diabetic rats. Diabetologia 31, 220-225; doi: 10.1007/BF00571955
    • (1994) Diabetologia , vol.31 , pp. 220-225
    • Cameron, N.E.1    Cotter, M.A.2
  • 12
    • 0028207046 scopus 로고
    • Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats
    • Cameron N. E., Cotter M. A., Archibald V., Dines K. C., Maxfield E. K. (1994): Anti-oxidant and pro-oxidant effects on nerve conduction velocity, endoneurial blood flow and oxygen tension in non-diabetic and streptozotocin-diabetic rats. Diabetologia 37, 449-459; doi:10.1007/ s001250050131 (Pubitemid 24133646)
    • (1994) Diabetologia , vol.37 , Issue.5 , pp. 449-459
    • Cameron, N.E.1    Cotter, M.A.2    Archibald, V.3    Dines, K.C.4    Maxfield, E.K.5
  • 13
    • 0031944812 scopus 로고    scopus 로고
    • Effect of a-lipoic acid on neurovascular function in diabetic rats: Interaction with essential fatty acids
    • doi: 10.1007/s001250050921
    • Cameron N. E., Cotter M. A., Horrobin D. H., Tritschler H. J. (1998): Effect of a-lipoic acid on neurovascular function in diabetic rats: interaction with essential fatty acids. Diabetologia 4, 390-399; doi: 10.1007/s001250050921
    • (1998) Diabetologia , vol.4 , pp. 390-399
    • Cameron, N.E.1    Cotter, M.A.2    Horrobin, D.H.3    Tritschler, H.J.4
  • 14
    • 0032836681 scopus 로고    scopus 로고
    • Effects of antioxidants on nerve and vascular dysfunction in experimental diabetes
    • doi:10.1016/S0168-8227(99)00043-51
    • Cameron N. E., Cotter M. A. (1999): Effects of antioxidants on nerve and vascular dysfunction in experimental diabetes. Diabetes Res. Clin. Pract. 45, 137-146; doi:10.1016/S0168-8227(99)00043-51
    • (1999) Diabetes Res. Clin. Pract. , vol.45 , pp. 137-146
    • Cameron, N.E.1    Cotter, M.A.2
  • 15
    • 0029862720 scopus 로고    scopus 로고
    • Structure-function relationships within peripheral nerves in diabetic neuropathy: The hydration hypothesis
    • DOI 10.1007/s001250050463
    • Eaton R. P., Quails C., Bicknell J., Sibbitt W. L. Jr., King M. K., Griffey R. H. (1996): Structure-function relationships within peripheral nerves in diabetic neuropathy: the hydration hypothesis. Diabetologia 39, 439-446; doi:10.1007/BF00400675 (Pubitemid 26093872)
    • (1996) Diabetologia , vol.39 , Issue.4 , pp. 439-446
    • Eaton, R.P.1    Quails, C.2    Bicknell, J.3    Sibbitt Jr., W.L.4    King, M.K.5    Griffey, R.H.6
  • 16
    • 0033764060 scopus 로고    scopus 로고
    • Alpha-lipoic acid: A multifunctional antioxidant that improves insulin sensitivity in patients with type II diabetes
    • doi:10.1089/15209150050194279
    • Evans J. L., Goldfine I. D. (2000): Alpha-lipoic acid: a multifunctional antioxidant that improves insulin sensitivity in patients with type II diabetes. Review. Diabetes Technol. Ther. 2, 401-413.; doi:10.1089/15209150050194279
    • (2000) Review. Diabetes Technol. Ther. , vol.2 , pp. 401-413
    • Evans, J.L.1    Goldfine, I.D.2
  • 17
    • 0346724201 scopus 로고    scopus 로고
    • Mechanism of mitochondrial dysfunction in diabetic sensory neuropathy
    • doi: 10.1111/j.10859489.2003.03028.x
    • Fernyhough P., Huang T. J., Verkhratsky A. (2003): Mechanism of mitochondrial dysfunction in diabetic sensory neuropathy. J. Peripher. Nerv. Syst. 8, 227-235; doi: 10.1111/j.10859489.2003.03028.x
    • (2003) J. Peripher. Nerv. Syst. , vol.8 , pp. 227-235
    • Fernyhough, P.1    Huang, T.J.2    Verkhratsky, A.3
  • 18
    • 0033212853 scopus 로고    scopus 로고
    • Stobadine protects against ischemia-reperfusion induced morphological alterations of cerebral microcirculation in dogs
    • DOI 10.1016/S0024-3205(99)00456-7, PII S0024320599004567
    • Franko J., Pomfy M., Nováková B., Benes L. (1999): Stobadine protects against ischemia-reperfusion induced morphological alterations of cerebral microcirculation in dogs. Life Sci. 65, 1963-1967; doi:10.1016/S0024-3205(99)00456-7 (Pubitemid 29506937)
    • (1999) Life Sciences , vol.65 , Issue.18-19 , pp. 1963-1967
    • Franko, J.1    Pomfy, M.2    Novakova, B.3    Benes, L.4
  • 19
    • 0034871855 scopus 로고    scopus 로고
    • The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat
    • DOI 10.1053/meta.2001.24914
    • Ford I., Cotter M. A., Cameron N. E., Greaves M. (2001): The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat. Metabolism 50, 868-875; doi: 10.1053/meta.2001. 24914 (Pubitemid 32755001)
    • (2001) Metabolism: Clinical and Experimental , vol.50 , Issue.8 , pp. 868-875
    • Ford, I.1    Cotter, M.A.2    Cameron, N.E.3    Greaves, M.4
  • 20
    • 0242495285 scopus 로고    scopus 로고
    • Alpha-lipoic acid treatment prevents the diabetes-induced attenuation of the afferent limb of the baroreceptor reflex in rats
    • doi:10.1016/j.autneu.2003.08.004
    • Gouty S., Regalia J., Cai F., Heike C. J. (2003): Alpha-lipoic acid treatment prevents the diabetes-induced attenuation of the afferent limb of the baroreceptor reflex in rats. Auton. Neurosci. 108, 32-44; doi:10.1016/j.autneu. 2003.08.004
    • (2003) Auton. Neurosci. , vol.108 , pp. 32-44
    • Gouty, S.1    Regalia, J.2    Cai, F.3    Heike, C.J.4
  • 21
    • 13444270631 scopus 로고    scopus 로고
    • Reactive oxygen species mediate abnormal contractile response to sympathetic nerve stimulation and noradrenaline in the vas deferens of chronically diabetic rats: Effects of in vivo treatment with antioxidants
    • doi:10.1111/j. 14728206.2004.00312.x
    • Günes A., Ceylan A., Sarioglu Y., Štefek M., Bauer V., Karasu C. (2005): Reactive oxygen species mediate abnormal contractile response to sympathetic nerve stimulation and noradrenaline in the vas deferens of chronically diabetic rats: effects of in vivo treatment with antioxidants. Fundam. Clin. Pharmacol. 19, 73-79; doi:10.1111/j. 14728206.2004.00312.x
    • (2005) Fundam. Clin. Pharmacol. , vol.19 , pp. 73-79
    • Günes, A.1    Ceylan, A.2    Sarioglu, Y.3    Štefek, M.4    Bauer, V.5    Karasu, C.6
  • 22
    • 0028102993 scopus 로고
    • Effect of diabetes, insulin, and glucose load on lipid peroxidation in the rat
    • doi: 10.1016/00260495(94)90042-90046
    • Habib M.P., Dickerson F.D., Mooradian A.D. (1994): Effect of diabetes, insulin, and glucose load on lipid peroxidation in the rat. Metabolism 43, 1442-1445; doi: 10.1016/00260495(94)90042-90046
    • (1994) Metabolism , vol.43 , pp. 1442-1445
    • Habib, M.P.1    Dickerson, F.D.2    Mooradian, A.D.3
  • 23
    • 0345676510 scopus 로고    scopus 로고
    • Antioxidant and pharmacodynamic effects of pyridoindole stobadine
    • doi:10.1016/S0306-3623(97)00300-5
    • Horáková L'., Stolc S. (1998): Antioxidant and pharmacodynamic effects of pyridoindole stobadine. Review. Gen. Pharmacol. 30, 627-638; doi:10.1016/S0306-3623(97)00300-5
    • (1998) Review. Gen. Pharmacol. , vol.30 , pp. 627-638
    • Horáková, L'.1    Stolc, S.2
  • 25
    • 0142044013 scopus 로고    scopus 로고
    • Role of lipids in chemical modification of proteins and development of complications in diabetes
    • doi:10.1042/BST0311413
    • Januszewski A. S., Alderson N. L., Metz T. O., Thorpe S. R., Baynes J. W. (2003): Role of lipids in chemical modification of proteins and development of complications in diabetes. Biochem. Soc. Trans. 31, 1413-1416; doi:10.1042/BST0311413
    • (2003) Biochem. Soc. Trans. , vol.31 , pp. 1413-1416
    • Januszewski, A.S.1    Alderson, N.L.2    Metz, T.O.3    Thorpe, S.R.4    Baynes, J.W.5
  • 26
    • 20444442574 scopus 로고    scopus 로고
    • Effect of the pyridoindole antioxidant stobadine on development of experimental diabetic cataract and on lens protein oxidation in rats: Comparison with vitamin e and BHT
    • Kyselova Z., Gajdosik A., Gajdosikova A., Ulicna O., Mihalova D., Karasu C., Stefek M. (2005): Effect of the pyridoindole antioxidant stobadine on development of experimental diabetic cataract and on lens protein oxidation in rats: comparison with vitamin E and BHT. MoL Vis. 11, 56-65 (Pubitemid 41358308)
    • (2005) Molecular Vision , vol.11 , pp. 56-65
    • Kyselova, Z.1    Gajdosik, A.2    Gajdosikova, A.3    Ulicna, O.4    Mihalova, D.5    Karasu, C.6    Stefek, M.7
  • 28
    • 0024510189 scopus 로고
    • In vitro correction of impaired Na+, K+-ATPase in diabetic nerve by protein kinase C agonists
    • Lattimer S. A., Sima A. A., Greene D. A. (1989): In vitro correction of impaired Na+, K+-ATPase in diabetic nerve by protein kinase C agonists. Am. J. Physiol. 256, 264-269
    • (1989) Am. J. Physiol. , vol.256 , pp. 264-269
    • Lattimer, S.A.1    Sima, A.A.2    Greene, D.A.3
  • 29
    • 0017179001 scopus 로고
    • Streptozotocin-induced pancreatic insulitis: New model of diabetes mellitus
    • doi: 10.1126/science. 180605
    • Like A. A., Rossini A. A. (1976): Streptozotocin-induced pancreatic insulitis: new model of diabetes mellitus. Science 193, 415-417; doi: 10.1126/science. 180605
    • (1976) Science , vol.193 , pp. 415-417
    • Like, A.A.1    Rossini, A.A.2
  • 30
    • 0343742202 scopus 로고
    • Ischaemic conduction failure and energy metabolism in experimental diabetic neuropathy
    • Low P. A., Ward K., Schmelzer J. D., Brimijoin S. (1985): Ischaemic conduction failure and energy metabolism in experimental diabetic neuropathy. Am. J. Physiol. 248, 457-462
    • (1985) Am. J. Physiol. , vol.248 , pp. 457-462
    • Low, P.A.1    Ward, K.2    Schmelzer, J.D.3    Brimijoin, S.4
  • 31
    • 0024814465 scopus 로고
    • Nerve blood flow and oxygen delivery in normal, diabetic and ischemic neuropathy
    • doi:10.1016/S0074-7742(08)60283-4
    • Low P. A., Lagerlund T. D., McManis P. G. (1989): Nerve blood flow and oxygen delivery in normal, diabetic and ischemic neuropathy. Int. Rev. Neurobiol. 31, 355-438; doi:10.1016/S0074-7742(08)60283-4
    • (1989) Int. Rev. Neurobiol. , vol.31 , pp. 355-438
    • Low, P.A.1    Lagerlund, T.D.2    McManis, P.G.3
  • 32
    • 0030961020 scopus 로고    scopus 로고
    • The roles of oxidative stress and antioxidant treatment in experimental diabetic neuropathy
    • Low P. A., Nickander K. K., Tritschler H. J. ( 1997): The roles of oxidative stress and antioxidant treatment in experimental diabetic neuropathy. Diabetes 46, 38-42
    • (1997) Diabetes , vol.46 , pp. 38-42
    • Low, P.A.1    Nickander, K.K.2    Tritschler, H.J.3
  • 33
    • 6844230710 scopus 로고    scopus 로고
    • α-Lipoic acid prevents the deficit in glucose uptake in experimental diabetic neuropathy
    • Low P. A., Schmelzer J. D., Zollman P. J., Tritschler H. J. (1996): α-Lipoic acid prevents the deficit in glucose uptake in experimental diabetic neuropathy. Diabetologia 39, A34
    • (1996) Diabetologia , vol.39
    • Low, P.A.1    Schmelzer, J.D.2    Zollman, P.J.3    Tritschler, H.J.4
  • 34
    • 0142211275 scopus 로고    scopus 로고
    • Pyridoxamine traps intermediates in lipid peroxidation reactions in vivo: Evidence on the role of lipids in chemical modification of protein and development of diabetic complications
    • doi: 10.1074/jbc.M304292200
    • Metz T. O., Alderson N. L., Chachich M. E., Thorpe S. R., Baynes J. W. (2003): Pyridoxamine traps intermediates in lipid peroxidation reactions in vivo: evidence on the role of lipids in chemical modification of protein and development of diabetic complications. J. Biol. Chem. 278, 42012-42019; doi: 10.1074/jbc.M304292200
    • (2003) J. Biol. Chem. , vol.278 , pp. 42012-42019
    • Metz, T.O.1    Alderson, N.L.2    Chachich, M.E.3    Thorpe, S.R.4    Baynes, J.W.5
  • 35
    • 0029090976 scopus 로고
    • Lipoic acid improves nerve blood flow, reduces oxidative stress and improves distal nerve conduction in experimental diabetic neuropathy
    • doi: 10.2337/diacare. 18.8.1160
    • Nagamatsu M., Nickander K. K., Schmelzer J. D., Raya A., Wittrock D. A., Tritschler H., Low P. A. (1995): Lipoic acid improves nerve blood flow, reduces oxidative stress and improves distal nerve conduction in experimental diabetic neuropathy. Diabetes Care 18, 1160-1167; doi: 10.2337/diacare. 18.8.1160
    • (1995) Diabetes Care , vol.18 , pp. 1160-1167
    • Nagamatsu, M.1    Nickander, K.K.2    Schmelzer, J.D.3    Raya, A.4    Wittrock, D.A.5    Tritschler, H.6    Low, P.A.7
  • 36
    • 33744902108 scopus 로고    scopus 로고
    • Effects of eugenol on nerve and vascular dysfunction in streptozotocin-diabetic rats
    • doi: 10.1055/S-2005-916262
    • Nangle M. R., Gibson T. M., Cotter M. A., Cameron N. E. (2006): Effects of eugenol on nerve and vascular dysfunction in streptozotocin-diabetic rats. Planta Med. 72, 494-500; doi: 10.1055/S-2005-916262
    • (2006) Planta Med. , vol.72 , pp. 494-500
    • Nangle, M.R.1    Gibson, T.M.2    Cotter, M.A.3    Cameron, N.E.4
  • 37
    • 0029070687 scopus 로고
    • Alpha-lipoic acid as a biological antioxidant
    • Review doi: 10.1016/0891-5849(95)00017-R
    • Packer L., Witt E. H., Tritschler H. J. (1995): Alpha-lipoic acid as a biological antioxidant (Review). Free Rad. Biol. Med. 19, 227-250; doi: 10.1016/0891-5849(95)00017-R
    • (1995) Free Rad. Biol. Med. , vol.19 , pp. 227-250
    • Packer, L.1    Witt, E.H.2    Tritschler, H.J.3
  • 38
    • 0030340574 scopus 로고    scopus 로고
    • Alpha-lipoic acid: The metabolic antioxidant
    • doi:10.1016/0891-5849(95)02129-9
    • Packer L., Tritschler H. J. (1996): Alpha-lipoic acid: the metabolic antioxidant. Free Rad. Biol. Med. 20, 625-626; doi:10.1016/0891-5849(95)02129-9
    • (1996) Free Rad. Biol. Med. , vol.20 , pp. 625-626
    • Packer, L.1    Tritschler, H.J.2
  • 39
    • 0034773628 scopus 로고    scopus 로고
    • Molecular aspects of lipoic acid in the prevention of diabetes complications
    • DOI 10.1016/S0899-9007(01)00658-X, PII S089990070100658X
    • Packer L., Kraemer K., Rimbach G. (2001): Molecular aspects of lipoic acid in the prevention of diabetes complications. Review. Nutrition 17, 888-895; doi:10.1016/S08999007(01)00658-X (Pubitemid 33001657)
    • (2001) Nutrition , vol.17 , Issue.10 , pp. 888-895
    • Packer, L.1    Kraemer, K.2    Rimbach, G.3
  • 41
    • 0027328844 scopus 로고
    • Hydroxyl radicals mediate injury to endothelium-dependent relaxation in diabetic rats
    • doi:10.1007/BF01076098
    • Pieper G. M., Langenstroer P., Gross G. J. ( 1993): Hydroxyl radicals mediate injury to endothelium-dependent relaxation in diabetic rats. MoL Cell. Biochem. 122, 139-145; doi:10.1007/BF01076098
    • (1993) MoL Cell. Biochem. , vol.122 , pp. 139-145
    • Pieper, G.M.1    Langenstroer, P.2    Gross, G.J.3
  • 42
    • 33746086028 scopus 로고    scopus 로고
    • Diabetic neuropathy and oxidative stress
    • doi:10.1002/dmrr.625
    • Pop-Busui R., Sima A., Stevens M. (2006): Diabetic neuropathy and oxidative stress. Diabetes Metab. Res. Rev. 22, 257-273; doi:10.1002/dmrr.625
    • (2006) Diabetes Metab. Res. Rev. , vol.22 , pp. 257-273
    • Pop-Busui, R.1    Sima, A.2    Stevens, M.3
  • 43
    • 0035068448 scopus 로고    scopus 로고
    • Ventricular arrhythmias following coronary artery occlusion in rats: Is the diabetic heart less or more sensitive to ischaemia?
    • doi: 10.1007/s003950170066
    • Ravingerova T., Neckar J., Kolar F., Stetka R., Volkovova K., Ziegelhöffer A., Styk J. (2001): Ventricular arrhythmias following coronary artery occlusion in rats: is the diabetic heart less or more sensitive to ischaemia ? Basic Res. Cardiol. 96, 160-168; doi: 10.1007/s003950170066
    • (2001) Basic Res. Cardiol. , vol.96 , pp. 160-168
    • Ravingerova, T.1    Neckar, J.2    Kolar, F.3    Stetka, R.4    Volkovova, K.5    Ziegelhöffer, A.6    Styk, J.7
  • 44
    • 0029076701 scopus 로고
    • Diabetes impairs DRG neuronal attachment to extracellular matrix protein in vitro
    • doi:10.1016/0361-9230(95)00057-L
    • Sango K., Horie H., Okamura A., Inoue S., Takenaka T. (1995): Diabetes impairs DRG neuronal attachment to extracellular matrix protein in vitro. Brain Res. Bull. 37, 533-537; doi:10.1016/0361-9230(95)00057-L
    • (1995) Brain Res. Bull. , vol.37 , pp. 533-537
    • Sango, K.1    Horie, H.2    Okamura, A.3    Inoue, S.4    Takenaka, T.5
  • 45
    • 0343308394 scopus 로고
    • Ischemic and reperfusion injury of rat peripheral nerve
    • doi:10.1073/pnas.86.5.1639
    • Schmelzer J. D., Zochodne D. W., Low P. A. (1989): Ischemic and reperfusion injury of rat peripheral nerve. Proc. Natl. Acad. Sci. U.S.A. 86, 1639-1642; doi:10.1073/pnas.86.5.1639
    • (1989) Proc. Natl. Acad. Sci. U.S.A. , vol.86 , pp. 1639-1642
    • Schmelzer, J.D.1    Zochodne, D.W.2    Low, P.A.3
  • 46
    • 0027511472 scopus 로고
    • Overt diabetic neuropathy: Repair of axoglial dysjuntion and axonal atrophy by aldose reductase inhibition and its correlation to improvement in nerve conduction velocity
    • doi:10.1111/j. 1464-5491.1993.tb00027.x
    • Sima A. A., Prashar A., Nathaniel V., Bril V., Werb M. R., Greene D. A. (1993): Overt diabetic neuropathy: repair of axoglial dysjuntion and axonal atrophy by aldose reductase inhibition and its correlation to improvement in nerve conduction velocity. Diabet. Med. 10, 115-121; doi:10.1111/j. 1464-5491.1993.tb00027.x
    • (1993) Diabet. Med. , vol.10 , pp. 115-121
    • Sima, A.A.1    Prashar, A.2    Nathaniel, V.3    Bril, V.4    Werb, M.R.5    Greene, D.A.6
  • 47
    • 0032789870 scopus 로고    scopus 로고
    • Experimental diabetic neuropathy: An update
    • doi:10.1007/s001250051227
    • Sima A. A., Sugimoto K. (1999): Experimental diabetic neuropathy: an update. Diabetologia 42, 773-788; doi:10.1007/s001250051227
    • (1999) Diabetologia , vol.42 , pp. 773-788
    • Sima, A.A.1    Sugimoto, K.2
  • 48
    • 48749127716 scopus 로고    scopus 로고
    • Protective effect of stobadine on NCV in streptozotocin-induced diabetic rats: Augmentation by vitamin E
    • Skalska S., Kyselova Z., Gajdosikova A., Karasu C., Stefek M., Stole S. (2008): Protective effect of stobadine on NCV in streptozotocin-induced diabetic rats: augmentation by vitamin E. Gen. Physiol. Biophys. 27, 106-114
    • (2008) Gen. Physiol. Biophys. , vol.27 , pp. 106-114
    • Skalska, S.1    Kyselova, Z.2    Gajdosikova, A.3    Karasu, C.4    Stefek, M.5    Stole, S.6
  • 49
    • 0034894589 scopus 로고    scopus 로고
    • Dietary supplementation of the pyridoindole antioxidant stobadine reduces vascular impairment in streptozotocin-diabetic rats
    • doi:10.1358/mf.2001.23.3.627943
    • Sotnikova R., Stefek M., Okruhlicova L., Navarova J., Bauer V., Gajdosik A., Gajdosiková A. (2001): Dietary supplementation of the pyridoindole antioxidant stobadine reduces vascular impairment in streptozotocin-diabetic rats. Methods Find. Exp. Clin. Pharmacol. 23, 121-129; doi:10.1358/mf.2001.23.3. 627943
    • (2001) Methods Find. Exp. Clin. Pharmacol. , vol.23 , pp. 121-129
    • Sotnikova, R.1    Stefek, M.2    Okruhlicova, L.3    Navarova, J.4    Bauer, V.5    Gajdosik, A.6    Gajdosiková, A.7
  • 51
    • 0029928812 scopus 로고    scopus 로고
    • The pyridoindole antioxidant stobadine inhibited glycation induced absorbance and fluorescence changes in albumin
    • DOI 10.1007/BF00571938
    • Stefek M., Drozdikova I., Vajdova K (1996): The pyridoindole antioxidant stobadine inhibited glycation-induced absorbance and fluorescence changes in albumin. Acta Diabetol. 33, 35-40; doi:10.1007/BF00571938 (Pubitemid 26096154)
    • (1996) Acta Diabetologica , vol.33 , Issue.1 , pp. 35-40
    • Stefek, M.1    Drozdikova, I.2    Vajdova, K.3
  • 54
    • 0346667197 scopus 로고    scopus 로고
    • The pyridoindole antioxidant stobadine attenuates histochemical changes in kidney of streptozotocin-induced diabetic rats
    • DOI 10.1078/0065-1281-00681
    • Stefek M., Tribulova N., Gajdosik A., Gajdosikova A. (2002b): The pyridoindole antioxidant stobadine attenuates histochemical changes in kidney of streptozotocin-induced diabetic rats. Acta Histochem. 104, 413-417; doi: 10.1078/00651281-00681 (Pubitemid 36041809)
    • (2002) Acta Histochemica , vol.104 , Issue.4 , pp. 413-417
    • Stefek, M.1    Tribulova, N.2    Gajdosik, A.3    Gajdosikova, A.4
  • 55
    • 0025936799 scopus 로고
    • Glucose availability and sensitivity to anoxia of isolated rat peroneal nerve
    • Strupp M., Jund R., Schneider U., Grafe P. (1991): Glucose availability and sensitivity to anoxia of isolated rat peroneal nerve. Am. J. Physiol. 261, E389-394
    • (1991) Am. J. Physiol. , vol.261
    • Strupp, M.1    Jund, R.2    Schneider, U.3    Grafe, P.4
  • 56
    • 26244439141 scopus 로고    scopus 로고
    • Alpha-lipoic acid in the treatment of autonomic diabetic neuropathy (controlled, randomized, open-label study)
    • Tankova T., Koev D., Dakovska L. (2004): Alpha-lipoic acid in the treatment of autonomic diabetic neuropathy (controlled, randomized, open-label study). Rom. J. Intern. Med. 42, 457-464
    • (2004) Rom. J. Intern. Med. , vol.42 , pp. 457-464
    • Tankova, T.1    Koev, D.2    Dakovska, L.3
  • 57
    • 0028151070 scopus 로고
    • The effect of hyperglycaemia on function of rat isolated mesenteric resistance artery
    • Taylor P. D., Poston L. (1994): The effect of hyperglycaemia on function of rat isolated mesenteric resistance artery. Br. J. Pharmacol. 113, 801-808
    • (1994) Br. J. Pharmacol. , vol.113 , pp. 801-808
    • Taylor, P.D.1    Poston, L.2
  • 58
    • 0037409980 scopus 로고    scopus 로고
    • Pentose phosphate pathway, glutathione-dependent enzymes and antioxidant defense during oxidative stress in diabetic rodent brain and peripheral organs: Effects of stobadine and vitamin E
    • doi: 10.1023/A:1023202805255
    • Ulusu N. N., Sahilli M., Avci A., Canbolat O., Ozansoy G., Ari N., Bali M., Stefek M., Stolc S., Gajdosik A., Karasu C. (2003): Pentose phosphate pathway, glutathione-dependent enzymes and antioxidant defense during oxidative stress in diabetic rodent brain and peripheral organs: effects of stobadine and vitamin E. Neurochem. Res. 28, 815-823; doi: 10.1023/A:1023202805255
    • (2003) Neurochem. Res. , vol.28 , pp. 815-823
    • Ulusu, N.N.1    Sahilli, M.2    Avci, A.3    Canbolat, O.4    Ozansoy, G.5    Ari, N.6    Bali, M.7    Stefek, M.8    Stolc, S.9    Gajdosik, A.10    Karasu, C.11
  • 60
    • 0035000944 scopus 로고    scopus 로고
    • Glutathione and alpha-lipoate in diabetic rats: Nerve function, blood flow and oxidative state
    • doi:10.1046/j.1365-2362.2001.00832.x
    • Van Dam P. S., Van Asbeck B. S., Van Oirschot J. F., Biessels G. J., Hamers F. P, Marx J. J. (2001): Glutathione and alpha-lipoate in diabetic rats: nerve function, blood flow and oxidative state. Eur. J. Clin. Invest. 31, 417-424; doi:10.1046/j.1365-2362.2001.00832.x
    • (2001) Eur. J. Clin. Invest. , vol.31 , pp. 417-424
    • Van Dam, P.S.1    Van Asbeck, B.S.2    Van Oirschot, J.F.3    Biessels, G.J.4    Hamers, F.P.5    Marx, J.J.6
  • 61
    • 38049136702 scopus 로고    scopus 로고
    • Diabetic neuropathy: New strategies for treatment
    • Varkonyi T., Kempler P. (2008): Diabetic neuropathy: new strategies for treatment. Diabetes Obes. Metab. 10, 99-108
    • (2008) Diabetes Obes. Metab. , vol.10 , pp. 99-108
    • Varkonyi, T.1    Kempler, P.2
  • 62
    • 33748362172 scopus 로고    scopus 로고
    • Effect of the pyridoindole antioxidant stobadine on the cardiac Na(+),K(+)-ATPase in rats with streptozotocin-induced diabetes
    • Vlkovicová J., Javorková V., Stefek M., Kysel'ová Z., Gajdosíková A., Vrbjar N. (2006): Effect of the pyridoindole antioxidant stobadine on the cardiac Na(+),K(+)-ATPase in rats with streptozotocin-induced diabetes. Gen. Physiol. Biophys. 25, 111-124
    • (2006) Gen. Physiol. Biophys. , vol.25 , pp. 111-124
    • Vlkovicová, J.1    Javorková, V.2    Stefek, M.3    Kysel'Ová, Z.4    Gajdosíková, A.5    Vrbjar, N.6
  • 64
    • 8544220372 scopus 로고    scopus 로고
    • Ischemia-reperfusion injury of peripheral nerve in experimental diabetic neuropathy
    • doi:10.1016/j.jns.2004.09.020
    • Wang Y., Schmelzer J. D., Schmeichel A., Iida H., Low P. A. (2004): Ischemia-reperfusion injury of peripheral nerve in experimental diabetic neuropathy. J. Neurol. Sci. 227, 101-107; doi:10.1016/j.jns.2004.09.020
    • (2004) J. Neurol. Sci. , vol.227 , pp. 101-107
    • Wang, Y.1    Schmelzer, J.D.2    Schmeichel, A.3    Iida, H.4    Low, P.A.5
  • 66
    • 34249990014 scopus 로고    scopus 로고
    • Effects of stobadine and vitamin E in diabetes-induced retinal abnormalities: Involvement of oxidative stress
    • doi:10.1016/j.arcmed.2007.02.006
    • Yülek F., Or M., Ozoǵul C., Isik A. C., Ari N., Śtefek M., Bauer V., Karasu C. (2007): Effects of stobadine and vitamin E in diabetes-induced retinal abnormalities: involvement of oxidative stress. Arch. Med. Res. 38, 503-511; doi:10.1016/j.arcmed.2007.02.006
    • (2007) Arch. Med. Res. , vol.38 , pp. 503-511
    • Yülek, F.1    Or, M.2    Ozoǵul, C.3    Isik, A.C.4    Ari, N.5    Śtefek, M.6    Bauer, V.7    Karasu, C.8
  • 67
    • 0033212923 scopus 로고    scopus 로고
    • Prevention of processes coupled with free radical formation prevents also the development of calcium-resistance in the diabetic heart
    • doi:10.1016/S0024-3205(99)00464-6
    • Ziegelhöffer A., Styk J., Ravingerová T., Seboková J., Volkovová K., Waczulíková I., Cársky J., Dzurba A., Docolomanský P. (1999): Prevention of processes coupled with free radical formation prevents also the development of calcium-resistance in the diabetic heart. Life Sci. 65, 1999-2001; doi:10.1016/S0024-3205(99)00464-6
    • (1999) Life Sci. , vol.65 , pp. 1999-2001
    • Ziegelhöffer, A.1    Styk, J.2    Ravingerová, T.3    Seboková, J.4    Volkovová, K.5    Waczulíková, I.6    Cársky, J.7    Dzurba, A.8    Docolomanský, P.9
  • 68
    • 0030884244 scopus 로고    scopus 로고
    • Alpha-lipoic acid in the treatment of diabetic peripheral and cardiac autonomic neuropathy
    • Ziegler D., Gries F. A. (1997): Alpha-lipoic acid in the treatment of diabetic peripheral and cardiac autonomic neuropathy. Diabetes 46, S62-66 (Pubitemid 27377401)
    • (1997) Diabetes , vol.46 , Issue.SUPPL. 2
    • Ziegler, D.1    Gries, F.A.2
  • 69
    • 0032702870 scopus 로고    scopus 로고
    • Alpha-lipoic acid in the treatment of diabetic polyneuropathy in Germany: Current evidence from clinical trials
    • doi:10.1055/s-0029-1212132
    • Ziegler D., Reljnovic M., Mehnert H., Gries F. A. (1999): Alpha-lipoic acid in the treatment of diabetic polyneuropathy in Germany: Current evidence from clinical trials. Exp. Clin. Endocrinol. Diabetes 107, 421-430; doi:10.1055/s-0029-1212132
    • (1999) Exp. Clin. Endocrinol. Diabetes , vol.107 , pp. 421-430
    • Ziegler, D.1    Reljnovic, M.2    Mehnert, H.3    Gries, F.A.4
  • 70
    • 2642548826 scopus 로고    scopus 로고
    • Thioctic acid for patients with symptomatic diabetic polyneuropathy: A critical review
    • doi: 10.2165/00024677-200403030-00005
    • Ziegler D. (2004): Thioctic acid for patients with symptomatic diabetic polyneuropathy: a critical review. Treat. Endocrinol. 3, 173-189; doi: 10.2165/00024677-200403030-00005
    • (2004) Treat. Endocrinol. , vol.3 , pp. 173-189
    • Ziegler, D.1
  • 71
    • 41149095006 scopus 로고    scopus 로고
    • Treatment of diabetic neuropathy and neuropathic pain: How far have we come?
    • doi:10.2337/dc08-s263
    • Ziegler D. (2008): Treatment of diabetic neuropathy and neuropathic pain: how far have we come? Diabetes Care 31, S255-261; doi:10.2337/dc08-s263
    • (2008) Diabetes Care , vol.31
    • Ziegler, D.1


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