Communication between tandem cAMP binding domains in the regulatory subunit of protein kinase A-Iα as revealed by domain-silencing mutations

Journal of Biological Chemistry

Volumn 285, Issue 20, 2010, Pages 15523-15537

  McNicholl, E Tyler ^a   Das, Rahul ^a   SilDas, Soumita ^a   Taylor, Susan S ^b   Melacini, Giuseppe ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING DOMAIN; HOT SPOT; INTER-DOMAIN; LEVEL OF DETAIL; NMR STUDIES; PROTEIN KINASE A; REGULATORY SUBUNITS; SECOND MESSENGER; STRUCTURAL INVESTIGATION; TETRAMERS; TWO DOMAINS; WILD TYPES;

CROSSTALK; PROTEINS;

FETAL MONITORING;

CYCLIC AMP DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT IALPHA;

ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GENE CASSETTE; GENE MAPPING; GENE MUTATION; GENE OVEREXPRESSION; GENE SILENCING; HYDROGEN BOND; HYDROPHOBICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

AMINO ACID SEQUENCE; BINDING SITES; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASE TYPE I; GENE SILENCING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 77952068200     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.105783     Document Type: Article

References (38)

1. Berman, H. M., Ten Eyck, L. F., Goodsell, D. S., Haste, N. M., Kornev, A., and Taylor, S. S. (2005) Proc. Natl. Acad. Sci. U.S.A. 102, 45-50
2. Shabb, J. B. (2001) Chem. Rev. 101, 2381-2411
3. Dodge, K. L., Khouangsathiene, S., Kapiloff, M. S., Mouton, R., Hill, E. V., Houslay, M. D., Langeberg, L. K., and Scott, J. D. (2001) EMBO J. 20, 1921-1930
4. Kopperud, R., Krakstad, C., Selheim, F., and Døskeland, S. O. (2003) FEBS Lett. 546, 121-126
5. Taylor, S. S., Kim, C., Vigil, D., Haste, N. M., Yang, J., Wu, J., and Anand, G. S. (2005) Biochim. Biophys. Acta 1754, 25-37
6. Scott, J. D. (2006) Biochem. Soc. Trans. 34, 465-467
7. Kim, C., Cheng, C. Y., Saldanha, S. A., and Taylor, S. S. (2007) Cell 130, 1032-1043
8. Su, Y., Dostmann, W. R., Herberg, F. W., Durick, K., Xuong, N. H., Ten Eyck, L., Taylor, S. S., and Varughese, K. I. (1995) Science 269, 807-813
9. Wu, J., Jones, J. M., Nguyen-Huu, X., Ten Eyck, L. F., and Taylor, S. S. (2004) Biochemistry 43, 6620-6629
10. Wu, J., Brown, S., Xuong, N. H., and Taylor, S. S. (2004) Structure 12, 1057-1065
11. Kim, C., Xuong, N. H., and Taylor, S. S. (2005) Science 307, 690-696
12. Rehmann, H., Prakash, B., Wolf, E., Rueppel, A., de Rooij, J., Bos, J. L., and Wittinghofer, A. (2003) Nat. Struct. Biol. 10, 26-32
13. Kornev, A. P., Taylor, S. S., and Ten Eyck, L. F. (2008) PLoS Comput. Biol. 4, 1-9
14. Das, R., and Melacini, G. (2007) J. Biol. Chem. 282, 581-593
15. Das, R., Esposito, V., Abu-Abed, M., Anand, G. S., Taylor, S. S., and Melacini, G. (2007) Proc. Natl. Acad. Sci. U.S.A. 104, 93-98
16. Abu-Abed, M., Das, R., Wang, L., and Melacini, G. (2007) Proteins 69, 112-124
17. Mazhab-Jafari, M. T., Das, R., Fotheringham, S. A., SilDas, S., Chowdhury, S., and Melacini, G. (2007) J. Am. Chem. Soc. 129, 14482-14492
18. Das, R., Mazhab-Jafari, M. T., Chowdhury, S., SilDas, S., Selvaratnam, R., and Melacini, G. (2008) J. Biol. Chem. 283, 19691-19703
19. Das, R., Chowdhury, S., Mazhab-Jafari, M. T., Sildas, S., Selvaratnam, R., and Melacini, G. (2009) J. Biol. Chem. 284, 23682-23696
20. Kannan, N., Wu, J., Anand, G. S., Yooseph, S., Neuwald, A. F., Venter, J. C., and Taylor, S. S. (2007) Genome Biology 8, R264.1-R264.13
21. Herberg, F. W., Taylor, S. S., and Dostmann, W. R. G. (1996) Biochemistry 35, 2934-2942
22. Englander, J., Cohen, L., Arshava, B., Estephan, R., Becker, J. M., and Naider, F. (2006) Biopolymers 84, 508-518
23. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
24. Delaglio, F., Grzesiek, S., Vuister, G. W., Zhu, G., Pfeifer, J., and Bax, A. (1995) J. Biomol. NMR 6, 277-293
25. Goddard, T. D., and Kneller, D. G. (2006) SPARKY 3, University of California, San Francisco, CA
26. Neal, S., Nip, A. M., Zhang, H., and Wishart, D. S. (2003) J. Biomol. NMR 26, 215-240
27. Eghbalnia, H. R., Wang, L., Bahrami, A., Assadi, A., and Markley, J. L. (2005) J. Biomol. NMR 32, 71-81
28. Das, R., Abu-Abed, M., and Melacini, G. (2006) J. Am. Chem. Soc. 128, 8406-8407
29. Tollinger, M., Skrynnikov, N. R., Mulder, F. A., Forman-Kay, J. D., and Kay, L. E. (2001) J. Am. Chem. Soc. 123, 11341-11352
30. Herberg, F. W., Dostmann, W. R., Zorn, M., Davis, S. J., and Taylor, S. S. (1994) Biochemistry 33, 7485-7494
31. Rehmann, H., Wittinghofer, A., and Bos, J. L. (2007) Nat. Rev. Mol. Cell Biol. 8, 63-73
32. Esposito, V., Sjoberg, T., Das, R., Brown, S., Taylor, S. S., and Melacini, G. (2006) J. Biomol. NMR 36, 64
33. Cànaves, J. M., Leon, D. A., and Taylor, S. S. (2000) Biochemistry 39, 15022-15031
34. Seguí-Lines, G., Gavina, J. M., D'Amaral, J. C., and Britz-McKibbin, P. (2007) Analyst 132, 741-744
35. Luque, I., Leavitt, S. A., and Freire, E. (2002) Annu. Rev. Biophys. Biomol. Struct. 31, 235-256
36. Cheng, C. Y., Yang, J., Taylor, S. S., and Blumenthal, D. K. (2009) J. Biol. Chem. 284, 35916-35925
37. Anand, G., Taylor, S. S., and Johnson, D. A. (2007) Biochemistry 46, 9283-9291
38. Vigil, D., Blumenthal, D. K., Taylor, S. S., and Trewhella, J. (2005) J. Biol. Chem. 280, 35521-35527