An improved ivermectin-activated chloride channel receptor for inhibiting electrical activity in defined neuronal populations

Journal of Biological Chemistry

Volumn 285, Issue 20, 2010, Pages 14890-14897

  Lynagh, Timothy ^a   Lynch, Joseph W ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN FUNCTIONS; CHLORIDE CHANNELS; DELIVERY METHODS; DELIVERY PROBLEMS; ELECTRICAL ACTIVITIES; FUNCTIONAL EXPRESSION; G PROTEIN COUPLED RECEPTORS; GLYCINE RECEPTOR; GLYCINE RESIDUES; HALORHODOPSIN; IN-VIVO; IVERMECTIN; NEURONAL ACTIVITIES; NEURONAL POPULATIONS; SYSTEMIC ADMINISTRATION;

CHLORINE COMPOUNDS; NEUROPHYSIOLOGY;

BRAIN;

ALPHA 1 GLYCINE RECEPTOR; AMINO ACID RECEPTOR; CHLORIDE CHANNEL; GLUTAMATE GATED CHLORIDE CHANNEL RECEPTOR; GLYCINE RECEPTOR; IVERMECTIN; UNCLASSIFIED DRUG;

ARTICLE; CHANNEL GATING; CONTROLLED STUDY; ELECTRIC CONDUCTIVITY; GENE ACTIVATION; GENE EXPRESSION; GENE IDENTIFICATION; GENE LOCATION; GENE MUTATION; GENE SILENCING; HUMAN; HUMAN CELL; NERVE CELL; NERVE CELL MEMBRANE CONDUCTANCE; NERVOUS SYSTEM ELECTROPHYSIOLOGY; PRIORITY JOURNAL; SENSITIVITY ANALYSIS;

ANIMALS; CELL LINE; CHLORIDE CHANNELS; HUMANS; IVERMECTIN; MALE; MUTATION; NEURONS; RATS; RATS, WISTAR; RECEPTORS, GLYCINE;

BACTERIA (MICROORGANISMS); INVERTEBRATA;

EID: 77952066919     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.107789     Document Type: Article

References (47)

1. Kramer, R. H., Fortin, D. L., and Trauner, D. (2009) Curr. Opin. Neurobiol. 19, 544-552
2. Luo, L., Callaway, E. M., and Svoboda, K. (2008) Neuron 57, 634-660
3. Zhang, F., Wang, L. P., Brauner, M., Liewald, J. F., Kay, K., Watzke, N., Wood, P. G., Bamberg, E., Nagel, G., Gottschalk, A., and Deisseroth, K. (2007) Nature 446, 633-639
4. Arrenberg, A. B., Del Bene, F., and Baier, H. (2009) Proc. Natl. Acad. Sci. U.S.A. 106, 17968-17973
5. Chow, B. Y., Han, X., Dobry, A. S., Qian, X., Chuong, A. S., Li, M., Henninger, M. A., Belfort, G. M., Lin, Y., Monahan, P. E., and Boyden, E. S. (2010) Nature 463, 98-102
6. Lechner, H. A., Lein, E. S., and Callaway, E. M. (2002) J. Neurosci. 22, 5287-5290
7. Tan, E. M., Yamaguchi, Y., Horwitz, G. D., Gosgnach, S., Lein, E. S., Goulding, M., Albright, T. D., and Callaway, E. M. (2006) Neuron 51, 157-170
8. Tan, W., Janczewski, W. A., Yang, P., Shao, X. M., Callaway, E. M., and Feldman, J. L. (2008) Nat. Neurosci. 11, 538-540
9. Wehr, M., Hostick, U., Kyweriga, M., Tan, A., Weible, A. P., Wu, H., Wu, W., Callaway, E. M., and Kentros, C. (2009) J. Neurophysiol. 102, 2554-2562
10. Zhang, Y., Narayan, S., Geiman, E., Lanuza, G. M., Velasquez, T., Shanks, B., Akay, T., Dyck, J., Pearson, K., Gosgnach, S., Fan, C. M., and Goulding, M. (2008) Neuron 60, 84-96
11. Zhou, Y., Won, J., Karlsson, M. G., Zhou, M., Rogerson, T., Balaji, J., Neve, R., Poirazi, P., and Silva, A. J. (2009) Nat. Neurosci. 12, 1438-1443
12. Li, P., Slimko, E. M., and Lester, H. A. (2002) FEBS Lett. 528, 77-82
13. Slimko, E. M., McKinney, S., Anderson, D. J., Davidson, N., and Lester, H. A. (2002) J Neurosci 22, 7373-7379
14. Omura, S. (2008) Int. J. Antimicrob. Agents 31, 91-98
15. Lerchner, W., Xiao, C., Nashmi, R., Slimko, E. M., van Trigt, L., Lester, H. A., and Anderson, D. J. (2007) Neuron 54, 35-49
16. Adelsberger, H., Lepier, A., and Dudel, J. (2000) Eur. J. Pharmacol. 394, 163-170
17. Dawson, G. R., Wafford, K. A., Smith, A., Marshall, G. R., Bayley, P. J., Schaeffer, J. M., Meinke, P. T., and McKernan, R. M. (2000) J. Pharmacol. Exp. Ther. 295, 1051-1060
18. Shan, Q., Haddrill, J. L., and Lynch, J. W. (2001) J. Biol. Chem. 276, 12556-12564
19. Cully, D. F., Vassilatis, D. K., Liu, K. K., Paress, P. S., Van der Ploeg, L. H., Schaeffer, J. M., and Arena, J. P. (1994) Nature 371, 707-711
20. McCavera, S., Rogers, A. T., Yates, D. M., Woods, D. J., and Wolstenholme, A. J. (2009) Mol. Pharmacol. 75, 1347-1355
21. Wolstenholme, A. J., and Rogers, A. T. (2005) Parasitology 131, S85-95
22. Bormann, J., Rundström, N., Betz, H., and Langosch, D. (1993) EMBO J. 12, 3729-3737
23. Franke, C., Hatt, H., and Dudel, J. (1986) Journal of Comparative Physiology A: Neuroethology, Sensory, Neural, and Behavioral Physiology 159, 591-609
24. Macdonald, R. L., and Olsen, R. W. (1994) Annu. Rev. Neurosci. 17, 569-602
25. Gilbert, D. F., Islam, R., Lynagh, T., Lynch, J. W., and Webb, T. I. (2009) Front Mol. Neurosci. 2, 17
26. Unwin, N. (2005) J. Mol. Biol. 346, 967-989
27. Chen, X., Cromer, B., Webb, T. I., Yang, Z., Hantke, J., Harvey, R. J., Parker, M. W., and Lynch, J. W. (2009) Neuropharmacology 56, 318-327
28. Hawthorne, R., Cromer, B. A., Ng, H. L., Parker, M. W., and Lynch, J. W. (2006) J. Neurochem. 98, 395-407
29. Heads, J. A., Hawthorne, R. L., Lynagh, T., and Lynch, J. W. (2008) J. Neurochem. 105, 1418-1427
30. Yang, Z., Cromer, B. A., Harvey, R. J., Parker, M. W., and Lynch, J. W. (2007) J. Neurochem. 103, 580-589
31. Grudzinska, J., Schemm, R., Haeger, S., Nicke, A., Schmalzing, G., Betz, H., and Laube, B. (2005) Neuron 45, 727-739
32. Gleitsman, K. R., Shanata, J. A., Frazier, S. J., Lester, H. A., and Dougherty, D. A. (2009) Biophys. J. 96, 3168-3178
33. Yamakura, T., Mihic, S. J., and Harris, R. A. (1999) J. Biol. Chem. 274, 23006-23012
34. Beato, M. (2008) J. Neurosci. 28, 7412-7425
35. Rajendra, S., Vandenberg, R. J., Pierce, K. D., Cunningham, A. M., French, P. W., Barry, P. H., and Schofield, P. R. (1995) EMBO J. 14, 2987-2998
36. Vafa, B., Lewis, T. M., Cunningham, A. M., Jacques, P., Lynch, J. W., and Schofield, P. R. (1999) J. Neurochem. 73, 2158-2166
37. Malosio, M. L., Marquèze-Pouey, B., Kuhse, J., and Betz, H. (1991) EMBO J. 10, 2401-2409
38. Pribilla, I., Takagi, T., Langosch, D., Bormann, J., and Betz, H. (1992) EMBO J. 11, 4305-4311
39. Keck, T., and White, J. A. (2009) Rev. Neurosci. 20, 13-22
40. McKellar, Q. A., and Benchaoui, H. A. (1996) J. Vet. Pharmacol. Therapy 19, 331-351
41. Siva, N. (2009) BMJ 339, b2755
42. Cotreau, M. M., Warren, S., Ryan, J. L., Fleckenstein, L., Vanapalli, S. R., Brown, K. R., Rock, D., Chen, C. Y., and Schwertschlag, U. S. (2003) J. Clin. Pharmacol. 43, 1108-1115
43. Griffith, J., Fletcher, N., Clemence, R., Blanchflower, S., and Brayden, D. J. (2005) J. Vet Pharmacol. Therapy 28, 257-265
44. Lespine, A., Martin, S., Dupuy, J., Roulet, A., Pineau, T., Orlowski, S., and Alvinerie, M. (2007) Eur. J. Pharm. Sci. 30, 84-94
45. Lee, V. K., Tiwary, A. K., Sharma-Reddy, P., Lieber, K. A., Taylor, D. K., and Mook, D. M. (2009) Comp. Med. 59, 227-233
46. Bali, M., Jansen, M., and Akabas, M. H. (2009) J. Neurosci. 29, 3083-3092
47. Lobo, I. A., and Harris, R. A. (2005) Int. Rev. Neurobiol. 65, 53-87