Antimalarial activities of aminooxy compounds

Antimicrobial Agents and Chemotherapy

Volumn 44, Issue 9, 2000, Pages 2540-2542

  Berger, B J ^a  

^a Defence Rsch Establishment Suffield   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOOXY DERIVATIVE; ANTIMALARIAL AGENT; CANALINE; CGP 48393A; CGP 50206A; CGP 51905A; CGP 52430A; CGP 54328A; CGP 55573A; CPG 54381A; EFLORNITHINE; ORNITHINE DECARBOXYLASE INHIBITOR; UNCLASSIFIED DRUG;

ANTIMALARIAL ACTIVITY; ARTICLE; DRUG POTENTIATION; MALARIA; NONHUMAN; PARASITOSIS; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

AMINOBUTYRIC ACIDS; ANIMALS; ANTIMALARIALS; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; EFLORNITHINE; ENZYME INHIBITORS; HUMANS; HYDROXYLAMINES; ORNITHINE DECARBOXYLASE; PLASMODIUM FALCIPARUM;

EID: 0033836277     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.44.9.2540-2542.2000     Document Type: Article

References (19)

1. Mode of interaction of aminooxy compounds with sheep liver serine hydroxymethyltransferase
2. Reactivity of the phosphopyridoxal groups of cystathionase
3. Methionine formation from α-ketomethiobutyrate in the trypanosomatid Crithidia fasciculata
4. DL-Canaline and 5-fluoromethylornithine. Comparison of two inactivators of ornithine amino-transferase
5. Polyamines and regulation of ornithine biosynthesis in Escherichia coli
6. Oxime formation between alpha-keto acids and L-canaline
7. Tyrosine aminotransferase catalyzes the final step of methionine recycling in Klebsiella pneumoniae
8. Polyamines as targets for therapeutic intervention
9. Analogs of 5-methylthioribose, a novel class of antiprotozoal agents
10. L-Canaline: A potent antimetabolite and anti-cancer agent from leguminous plants
11. A mechanism of L-canaline toxicity
12. Interaction of L-canaline with ornithine aminotransferase of the tobacco hornworm, Manduca sexta (Sphingidae)
13. L-Canavanine, a dietary nitrogen source for the seed predator Caryedes brasiliensis (Bruchidae)
14. Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine
15. Methionine recycling pathways and antimalarial drug design
16. Human malaria parasites in continuous culture
17. Treatment of gambiense sleeping sickness in the Sudan with oral DFMO (DL-alpha-difluoromethylornithine), an inhibitor of ornithine decarboxylase; First field trial
18. Structure-activity studies of L-canaline-mediated inhibition of porcine alanine aminotransferase