-
1
-
-
34547661571
-
Peroxisome proliferator-activated receptor structures: Ligand specificity, molecular switch and interactions with regulators
-
Zoete V, Grosdidier A, Michielin O. Peroxisome proliferator-activated receptor structures: Ligand specificity, molecular switch and interactions with regulators. Biochim Biophys Acta. 2007;1771:915-925.
-
(2007)
Biochim Biophys Acta
, vol.1771
, pp. 915-925
-
-
Zoete, V.1
Grosdidier, A.2
Michielin, O.3
-
2
-
-
0036043445
-
Role of the peroxisome proliferator-activated receptors (PPARS) in the regulation of lipids and inflammation control
-
Bocher V, Chinetti G, Fruchart JC. Role of the peroxisome proliferator-activated receptors (PPARS) in the regulation of lipids and inflammation control. J Soc Biol. 2002;196:47-52.
-
(2002)
J Soc Biol
, vol.196
, pp. 47-52
-
-
Bocher, V.1
Chinetti, G.2
Fruchart, J.C.3
-
3
-
-
0025132245
-
Activation of a member of the steroid hormone receptor superfamily by peroxisome proliferators
-
DOI 10.1038/347645a0
-
Issemann I, Green S. Activation of a member of the steriodhormone receptor superfamily by peroxisome proliferators. Nature. 1990;3:645-650. (Pubitemid 20356241)
-
(1990)
Nature
, vol.347
, Issue.6294
, pp. 645-650
-
-
Issemann, I.1
Green, S.2
-
4
-
-
1942518840
-
PPARs and the complex journey to obesity
-
Evans RM, Barish GD. PPARs and the complex journey to obesity. Nat Med. 2004;10:355-361.
-
(2004)
Nat Med
, vol.10
, pp. 355-361
-
-
Evans, R.M.1
Barish, G.D.2
-
5
-
-
33644954823
-
Peroxisome proliferator-activated receptor γ in malignant diseases
-
Wang T, Xu J, Yu X, et al. Peroxisome proliferator-activated receptor γ in malignant diseases. Crit Rev Oncol Hematol. 2006;58:1-14.
-
(2006)
Crit Rev Oncol Hematol
, vol.58
, pp. 1-14
-
-
Wang, T.1
Xu, J.2
Yu, X.3
-
6
-
-
35048833701
-
The potential of peroxisome proliferator-activated receptor gamma (PPARgamma) ligands in the treatment of hematological malignancies
-
DOI 10.2174/138955707781662618
-
Ulivieri C, Baldari CT. The potential of peroxisome proliferator- activated receptor gamma (PPAR gamma) ligands in the treatment of hematological malignancies. Mini Rev Med Chem. 2007;7:877-887. (Pubitemid 47554778)
-
(2007)
Mini-Reviews in Medicinal Chemistry
, vol.7
, Issue.9
, pp. 877-887
-
-
Ulivieri, C.1
Baldari, C.T.2
-
7
-
-
22144474079
-
Pivotal role of peroxisome proliferator-activated receptor gamma (PPARgamm) in regulation of erythroid progenitor cell proliferation and differentiation
-
DOI 10.1016/j.exphem.2005.05.003, PII S0301472X05002122
-
Nagasawa E, Abe Y, Nishimura J, et al. Pivotal role of peroxisome proliferator-activated receptor gamma (PPARgamma) in regulation of erythroid progenitor cell proliferation and differentiation. Exp Hematol. 2005;33:857-864 (Pubitemid 40982651)
-
(2005)
Experimental Hematology
, vol.33
, Issue.8
, pp. 857-864
-
-
Nagasawa, E.1
Abe, Y.2
Nishimura, J.3
Yanase, T.4
Nawata, H.5
Muta, K.6
-
8
-
-
38349166623
-
Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles
-
Ray DM, Spinelli SL, Pollock SJ, et al. Peroxisome proliferator-activated receptor gamma and retinoid X receptor transcription factors are released from activated human platelets and shed in microparticles. Thromb Haemost. 2008;99:86-95.
-
(2008)
Thromb Haemost
, vol.99
, pp. 86-95
-
-
Ray, D.M.1
Spinelli, S.L.2
Pollock, S.J.3
-
9
-
-
42949097448
-
A novel activity for substance P: Stimulation of peroxisome proliferator-activated receptor-gamma protein expression in human monocytes and macrophages
-
DOI 10.1038/bjp.2008.50, PII BJP200850
-
Amoruso A, Bardelli C, Gunella G, et al. A novel activity for substance P: Stimulation of peroxisome proliferator-activated receptor-gamma protein expression in human monocytes and macrophages. Br J Pharmacol. 2008;154:144-152. (Pubitemid 351620392)
-
(2008)
British Journal of Pharmacology
, vol.154
, Issue.1
, pp. 144-152
-
-
Amoruso, A.1
Bardelli, C.2
Gunella, G.3
Ribichini, F.4
Brunelleschi, S.5
-
10
-
-
23244448038
-
Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells
-
DOI 10.1007/s00280-005-1029-9
-
Liu J, Lu H, Huang R, et al. Peroxisome proliferator activated receptor-gamma ligands induced cell growth inhibition and its influence on matrix metalloproteinase activity in human myeloid leukemia cells. Cancer Chemother Pharmacol. 2005;56:400-408. (Pubitemid 41095403)
-
(2005)
Cancer Chemotherapy and Pharmacology
, vol.56
, Issue.4
, pp. 400-408
-
-
Liu, J.1
Lu, H.2
Huang, R.3
Lin, D.4
Wu, X.5
Lin, Q.6
Wu, X.7
Zheng, J.8
Pan, X.9
Peng, J.10
Song, Y.11
Zhang, M.12
Hou, M.13
Chen, F.14
-
11
-
-
2342465492
-
CDDO induces apoptosis via the intrinsic pathway in lymphoid cells
-
DOI 10.1038/sj.leu.2403328
-
Inoue S, Snowden RT, Dyer MJ, et al. CDDO induces apoptosis via the intrinsic pathway in lymphoid cells. Leukemia. 2004;18:948-952. (Pubitemid 38714619)
-
(2004)
Leukemia
, vol.18
, Issue.5
, pp. 948-952
-
-
Inoue, S.1
Snowden, R.T.2
Dyer, M.J.S.3
Cohen, G.M.4
-
12
-
-
25444498564
-
15-deoxy Delta12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor gamma in human erythroleukemia cells
-
Coyle AT, O'Keeffe MB, Kinsella BT. 15-deoxy Delta12,14-prostaglandin J2 suppresses transcription by promoter 3 of the human thromboxane A2 receptor gene through peroxisome proliferator-activated receptor gamma in human erythroleukemia cells. FEBS J. 2005;272:4754-4773.
-
(2005)
FEBS J
, vol.272
, pp. 4754-4773
-
-
Coyle, A.T.1
O'Keeffe, M.B.2
Kinsella, B.T.3
-
13
-
-
33645128230
-
Synthetic peroxisome proliferator-activated receptor gamma agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells
-
Coyle AT, Kinsella BT. Synthetic peroxisome proliferator-activated receptor gamma agonists rosiglitazone and troglitazone suppress transcription by promoter 3 of the human thromboxane A2 receptor gene in human erythroleukemia cells. Biochem Pharmacol. 2006;71:1308-1323.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 1308-1323
-
-
Coyle, A.T.1
Kinsella, B.T.2
-
14
-
-
33646430295
-
Growth inhibition and apoptosis in human Philadelphia chromosome-positive lymphoblastic leukemia cell lines by treatment with the dual PPARalpha/gamma ligand TZD18
-
Liu H, Zang C, Fenner MH. Growth inhibition and apoptosis in human Philadelphia chromosome-positive lymphoblastic leukemia cell lines by treatment with the dual PPARalpha/gamma ligand TZD18. Blood. 2006;107:3683-3692.
-
(2006)
Blood
, vol.107
, pp. 3683-3692
-
-
Liu, H.1
Zang, C.2
Fenner, M.H.3
-
15
-
-
13544263219
-
2 induces apoptosis in human malignant B cells: An effect associated with inhibition of NF-kappaB activity and down-regulation of antiapoptotic proteins
-
DOI 10.1182/blood-2004-04-1360
-
Piva R, Gianferretti P, Ciucci A. 15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis in human malignant B cells: An effect associated with inhibition of NF-kappa B activity and down-regulation of antiapoptotic proteins. Blood. 2005;105:1750-1758. (Pubitemid 40223699)
-
(2005)
Blood
, vol.105
, Issue.4
, pp. 1750-1758
-
-
Piva, R.1
Gianferretti, P.2
Ciucci, A.3
Taulli, R.4
Belardo, G.5
Santoro, M.G.6
-
16
-
-
33750720307
-
Induction of apoptosis in lymphoid and myeloid leukemia
-
DOI 10.1007/s11912-006-0071-z
-
Schimmer AD. Induction of apoptosis in lymphoid and myeloid leukemia. Curr Oncol Rep. 2006;8:430-436. (Pubitemid 44697772)
-
(2006)
Current Oncology Reports
, vol.8
, Issue.6
, pp. 430-436
-
-
Schimmer, A.D.1
-
17
-
-
0037790592
-
Apoptosis and interferons: Role of interferon-stimulated genes as mediators of apoptosis
-
DOI 10.1023/A:1023668705040
-
Chawla-Sarkar M, Lindner DJ, Liu YF. Apoptosis and interferons: Role of interferon-stimulated genes as mediators of apoptosis. Apoptosis. 2003;8:237-249. (Pubitemid 36749609)
-
(2003)
Apoptosis
, vol.8
, Issue.3
, pp. 237-249
-
-
Chawla-Sarkar, M.1
Lindner, D.J.2
Liu, Y.-F.3
Williams, B.R.4
Sen, G.C.5
Silverman, R.H.6
Borden, E.C.7
-
18
-
-
43449108570
-
Deregulation of the mitochondrial apoptotic machinery and development of molecular targeted drugs in acute myeloid leukemia
-
DOI 10.2174/156800908784293640
-
Del Poeta G, Bruno A, Del Principe MI, et al. Deregulation of the mitochondrial apoptotic machinery and development of molecular targeted drugs in acute myeloid leukemia. Curr Cancer Drug Targets. 2008;8:207-222. (Pubitemid 351666857)
-
(2008)
Current Cancer Drug Targets
, vol.8
, Issue.3
, pp. 207-222
-
-
Del Poeta, G.1
Bruno, A.2
Del Principe, M.I.3
Venditti, A.4
Maurillo, L.5
Buccisano, F.6
Stasi, R.7
Neri, B.8
Luciano, F.9
Siniscalchi, A.10
De Fabritiis, P.11
Amadori, S.12
-
19
-
-
0030464816
-
Flow cytometry study of cell cycle, apoptosis and drug resistance in acute leukemia
-
Lacombe F, Belloc F. Flow cytometry study of cell cycle, apoptosis and drug resistance in acute leukemia. Hematol Cell Ther. 1996;38:495-504. (Pubitemid 27022461)
-
(1996)
Hematology and Cell Therapy
, vol.38
, Issue.6
, pp. 495-504
-
-
Lacombe, F.1
Belloc, F.2
-
20
-
-
1542357606
-
Apoptosis pathways in cancer and cancer therapy
-
Debatin KM. Apoptosis pathways in cancer and cancer therapy. Cancer Immunol Immunother. 2004;53:153-197.
-
(2004)
Cancer Immunol Immunother
, vol.53
, pp. 153-197
-
-
Debatin, K.M.1
-
21
-
-
48249092267
-
Bcl-2 family members: Dual regulators of apoptosis and autophagy
-
Levine B, Sinha S, Kroemer G. Bcl-2 family members: Dual regulators of apoptosis and autophagy. Autophagy. 2008;4:600-606.
-
(2008)
Autophagy
, vol.4
, pp. 600-606
-
-
Levine, B.1
Sinha, S.2
Kroemer, G.3
-
22
-
-
0142117313
-
The Bcl-2 family: Roles in cell survival and oncogenesis
-
DOI 10.1038/sj.onc.1207102
-
Cory S, Huang DC, Adams JM. The Bcl-2 family: Roles in cell survival and oncogenesis. Oncogene. 2003;22:8590-8607 (Pubitemid 38028528)
-
(2003)
Oncogene
, vol.22
, Issue.53 REV. ISS. 7
, pp. 8590-8607
-
-
Cory, S.1
Huang, D.C.S.2
Adams, J.M.3
-
24
-
-
1442286330
-
The role of Bcl-2 family members in tumorigenesis
-
Kirkin V, Joos S, Zornig M. The role of Bcl-2 family members in tumorigenesis. Biochim Biophys Acta. 2004; 644:229-249.
-
(2004)
Biochim Biophys Acta
, vol.644
, pp. 229-249
-
-
Kirkin, V.1
Joos, S.2
Zornig, M.3
-
25
-
-
1542436707
-
Targeting Bcl-2-related proteins in cancer therapy
-
Manion MK, Hockenbery DM. Targeting Bcl-2-related proteins in cancer therapy. Cancer Biol Ther. 2003; 2:S105-114.
-
(2003)
Cancer Biol Ther
, vol.2
-
-
Manion, M.K.1
Hockenbery, D.M.2
-
26
-
-
0038324375
-
Caspase-mediated cell death in hematological malignancies: Theoretical considerations, methods of assessment, and clinical implications
-
Smolewski P, Darzynkiewicz Z, Robak T. Caspase-mediated cell death in hematological malignancies: Theoretical considerations, methods of assessment, and clinical implications. Leuk Lymphoma. 2003;44:1089-1104.
-
(2003)
Leuk Lymphoma
, vol.44
, pp. 1089-1104
-
-
Smolewski, P.1
Darzynkiewicz, Z.2
Robak, T.3
-
27
-
-
0036931366
-
Caspases: Keys in the ignition of cell death
-
Denault JB, Salvesen GS. Caspases: Keys in the ignition of cell death. Chem Rev. 2002;102:4489-4500.
-
(2002)
Chem Rev
, vol.102
, pp. 4489-4500
-
-
Denault, J.B.1
Salvesen, G.S.2
-
28
-
-
0037982618
-
Caspases as regulators of apoptosis and other cell functions
-
Philchenkov AA. Caspases as regulators of apoptosis and other cell functions. Biochemistry. 2003;68:365-376.
-
(2003)
Biochemistry
, vol.68
, pp. 365-376
-
-
Philchenkov, A.A.1
-
29
-
-
0043130473
-
Activation of caspases-3/7 is dispensable for idarubicin-induced apoptotic DNA fragmentation in human leukemia cells
-
Qi SN, Yoshida A, Ueda T. Activation of caspases-3/7 is dispensable for idarubicin-induced apoptotic DNA fragmentation in human leukemia cells. Int J Oncol. 2003;22:1123-1128.
-
(2003)
Int J Oncol
, vol.22
, pp. 1123-1128
-
-
Qi, S.N.1
Yoshida, A.2
Ueda, T.3
-
31
-
-
0037058964
-
Structure and zymogen activation of caspases
-
Donepudi M, Grutter MG. Structure and zymogen activation of caspases. Biophys Chem. 2002;101:145-153.
-
(2002)
Biophys Chem
, vol.101
, pp. 145-153
-
-
Donepudi, M.1
Grutter, M.G.2
-
32
-
-
37849035223
-
Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis
-
Mazumder S, Plesca D, Almasan A. Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis. Methods Mol Biol. 2008;414:13-21.
-
(2008)
Methods Mol Biol
, vol.414
, pp. 13-21
-
-
Mazumder, S.1
Plesca, D.2
Almasan, A.3
-
33
-
-
52649172153
-
Survivin: Key regulator of mitosis and apoptosis and novel target for cancer therapeutics
-
Mita AC, Mita MM, Nawrocki ST, et al. Survivin: Key regulator of mitosis and apoptosis and novel target for cancer therapeutics. Clin Cancer Res. 2008;14:5000-5005.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 5000-5005
-
-
Mita, A.C.1
Mita, M.M.2
Nawrocki, S.T.3
-
34
-
-
37549036729
-
Survivin, cancer networks and pathway-directed drug discovery
-
Altieri DC. Survivin, cancer networks and pathway-directed drug discovery. Nat Rev Cancer. 2008;8:61-70.
-
(2008)
Nat Rev Cancer
, vol.8
, pp. 61-70
-
-
Altieri, D.C.1
-
35
-
-
34447120194
-
Nuclear and cytoplasmic survivin: Molecular mechanism, prognostic, and therapeutic potential
-
DOI 10.1158/0008-5472.CAN-07-0494
-
Stauber RH, Mann W, Knauer SK. Nuclear and cytoplasmic survivin: Molecular mechanism, prognostic, and therapeutic potential. Cancer Res. 2007;67:5999-6002. (Pubitemid 47037475)
-
(2007)
Cancer Research
, vol.67
, Issue.13
, pp. 5999-6002
-
-
Stauber, R.H.1
Mann, W.2
Knauer, S.K.3
-
36
-
-
36448944759
-
Alternative splice variants of survivin as potential targets in cancer
-
DOI 10.2174/157016307782109652
-
Sampath J, Pelus LM. Alternative splice variants of survivin as potential targets in cancer. Curr Drug Discov Technol. 2007;4:174-191. (Pubitemid 350171819)
-
(2007)
Current Drug Discovery Technologies
, vol.4
, Issue.3
, pp. 174-191
-
-
Sampath, J.1
Pelus, L.M.2
|