The novel ketoprofen amides - Synthesis and biological evaluation as antioxidants, lipoxygenase inhibitors and cytostatic agents

Chemical Biology and Drug Design

Volumn 75, Issue 6, 2010, Pages 641-652

  Rajić, Zrinka ^a   Hadjipavlou Litina, Dimitra ^b   Pontiki, Eleni ^b   Kralj, Marijeta ^c   Šuman, Lidija ^c   Zorc, Branka ^a  

^a UNIVERSITY OF ZAGREB   (Croatia)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^c RUDER BO KOVI INSTITUTE   (Croatia)

Author keywords

Amide; Antioxidant activity; Cytostatic activity; Ketoprofen derivatives; Soybean lipoxygenase

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2 (3 BENZOYLPHENYL) N (CYCLOHEXANEMETHYL)PROPANAMIDE; 2 (3 BENZOYLPHENYL) N CYCLOPENTYLPROPANAMIDE; 2 (3 BENZOYLPHENYL) N PHENETHYLPROPANAMIDE; 2 (3 BENZYLPHENYL) N (2 HYDROXYETHYL)PROPANAMIDE; 2 (3 BENZYLPHENYL) N (3 HYDROXYPROPYL)PROPANAMIDE; 2 (3 BENZYLPHENYL) N (CYCLOHEXANEMETHYL)PROPANAMIDE; 2 (3 BENZYLPHENYL) N CYCLOHEXYLPROPANAMIDE; 2 (3 BENZYLPHENYL) N CYCLOPENTYLPROPANAMIDE; 2 (3 BENZYLPHENYL) N ETHOXYPROPANAMIDE; 2 (3 BENZYLPHENYL) N METHOXYPROPANAMIDE; 2 (3 BENZYLPHENYL) N PHENETHYLPROPANAMIDE; 2 (3 BENZYLPHENYL) N,N BIS(3 HYDROXYETHYL)PROPANAMIDE; 2 (3 BENZYLPHENYL)PROPANAMIDE; 2 [3 [HYDROXY(PHENYL)METHYL]PHENYL] N PHENETHYL PROPANAMIDE; ANTIOXIDANT; KETOPROFEN DERIVATIVE; LIPOXYGENASE; N BENZHYDRYL 2 (3 BENZOYLPHENYL)PROPANAMIDE; N BENZHYDRYL 2 (3 BENZYLPHENYL)PROPANAMIDE; N BENZHYDRYL 2 [3 [HYDROXY(PHENYL)METHYL]PHENYL]PROPANAMIDE; N BENZYL 2 (3 BENZOYLPHENYL)PROPANAMIDE; N BENZYL 2 (3 BENZYLPHENYL)PROPANAMIDE; N BENZYL 2 [3 [HYDROXY(PHENYL)METHYL]PHENYL]PROPANAMIDE; N BENZYLOXY 2 (3 BENZYLPHENYL)PROPANAMIDE; N CYCLOHEXANEMETHYL 2 [3 [HYDROXY(PHENYL)METHYL]PHENYL]PROPANAMIDE; N CYCLOHEXYL 2 [3 [HYDROXY(PHENYL)METHYL]PHENYL]PROPANAMIDE; N CYCLOPENTYL 2 [3 [HYDROXY(PHENYL)METHYL]PHENYL]PROPANAMIDE; N HYDROXY 2 [3 [HYDROXY(PHENYL)METHYL]PHENYL]PROPANAMIDE; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANTIOXIDANT ACTIVITY; ARTICLE; CLONOGENIC ASSAY; CONTROLLED STUDY; CYTOSTASIS; DRUG MECHANISM; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INHIBITION; IC 50; LIPID PEROXIDATION; LIPOPHILICITY; PRIORITY JOURNAL;

ANTIOXIDANTS; CELL LINE, TUMOR; CYTOSTATIC AGENTS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; KETOPROFEN; LIPOXYGENASE; LIPOXYGENASE INHIBITORS; STRUCTURE-ACTIVITY RELATIONSHIP;

GLYCINE MAX;

EID: 77951959254     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.00963.x     Document Type: Article

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