Multidimensional drug design: Simultaneous analysis of binding and relative efficacy profiles of n6-substituted-4′-thioadenosines A 3 adenosine receptor agonists

Chemical Biology and Drug Design

Volumn 75, Issue 6, 2010, Pages 607-618

  Cruz Monteagudo, Maykel ^a,b   Cordeiro, M Natália D S ^a   Teijeira, Marta ^c   González, Maykel P ^b   Borges, Fernanda ^a  

^a UNIVERSITY OF PORTO   (Portugal)

^b CENTRAL UNIVERSITY OF LAS VILLAS   (Cuba)

^c UNIVERSITY OF VIGO   (Spain)

Author keywords

A3 adenosine receptor agonists; Belief theory; Chemoinformatics; Desirability theory; Drug discovery; Ligand based virtual screening; Simultaneous analysis

Indexed keywords

ADENOSINE A3 RECEPTOR AGONIST;

ARTICLE; BINDING AFFINITY; COMBINATORIAL LIBRARY; CONTROLLED STUDY; DECISION THEORY; DRUG DESIGN; DRUG EFFICACY; DRUG RECEPTOR BINDING; HYDROPHOBICITY; MOLECULAR INTERACTION; PREDICTION; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; RELIABILITY; STATISTICAL MODEL; STATISTICAL SIGNIFICANCE;

ADENOSINE; ADENOSINE A3 RECEPTOR AGONISTS; ALGORITHMS; DRUG DESIGN; LIGANDS; PROTEIN BINDING; RECEPTOR, ADENOSINE A3; THIONUCLEOSIDES;

EID: 77951958514     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2010.00971.x     Document Type: Article

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