-
1
-
-
12444347534
-
A protein's final ESCRT
-
Babst M. A protein's final ESCRT. Traffic 2005;6:2-9.
-
(2005)
Traffic
, vol.6
, pp. 2-9
-
-
Babst, M.1
-
2
-
-
17844372539
-
Critical update and emerging trends in epidermal growth factor receptor targeting in cancer
-
Baselga J, Arteaga CL. Critical update and emerging trends in epidermal growth factor receptor targeting in cancer. J Clin Oncol 2005;23:2445-59.
-
(2005)
J Clin Oncol
, vol.23
, pp. 2445-2459
-
-
Baselga, J.1
Arteaga, C.L.2
-
3
-
-
0028865896
-
The protein product of the c-cbl oncogene rapidly complexes with the EGF receptor and is tyrosine phosphorylated following EGF stimulation
-
Bowtell DD, Langdon WY. The protein product of the c-cbl oncogene rapidly complexes with the EGF receptor and is tyrosine phosphorylated following EGF stimulation. Oncogene 1995;11:1561-7.
-
(1995)
Oncogene
, vol.11
, pp. 1561-1567
-
-
Bowtell, D.D.1
Langdon, W.Y.2
-
4
-
-
11344268358
-
Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor
-
Camp ER, Summy J, Bauer TW, Liu W, Gallick GE, Ellis LM. Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor. Clin Cancer Res 2005;11:397-405.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 397-405
-
-
Camp, E.R.1
Summy, J.2
Bauer, T.W.3
Liu, W.4
Gallick, G.E.5
Ellis, L.M.6
-
5
-
-
0023082137
-
Receptors for epidermal growth factor and other polypeptide mitogens
-
Carpenter G. Receptors for epidermal growth factor and other polypeptide mitogens. Annu Rev Biochem 1987;56:881-914.
-
(1987)
Annu Rev Biochem
, vol.56
, pp. 881-914
-
-
Carpenter, G.1
-
6
-
-
0022398187
-
Internalization of functional epidermal growth factor: receptor/kinase complexes in A-431 cells
-
Cohen S, Fava RA. Internalization of functional epidermal growth factor: receptor/kinase complexes in A-431 cells. J Biol Chem 1985;260:12351-8.
-
(1985)
J Biol Chem
, vol.260
, pp. 12351-12358
-
-
Cohen, S.1
Fava, R.A.2
-
7
-
-
0021204118
-
Autophosphorylation sites on the epidermal growth factor receptor
-
Downward J, Parker P, Waterfield MD. Autophosphorylation sites on the epidermal growth factor receptor. Nature 1984;311:483-5.
-
(1984)
Nature
, vol.311
, pp. 483-485
-
-
Downward, J.1
Parker, P.2
Waterfield, M.D.3
-
8
-
-
0035871936
-
High-performance liquid chromatographic analysis of the tyrphostin AG1478, a specific inhibitor of the epidermal growth factor receptor tyrosine kinase, in mouse plasma
-
Ellis AG, Nice EC, Weinstock J, Levitzki A, Burgess AW, Webster LK. High-performance liquid chromatographic analysis of the tyrphostin AG1478, a specific inhibitor of the epidermal growth factor receptor tyrosine kinase, in mouse plasma. J Chromatogr B Biomed Sci Appl. 2001;754:193-9.
-
(2001)
J Chromatogr B Biomed Sci Appl
, vol.754
, pp. 193-199
-
-
Ellis, A.G.1
Nice, E.C.2
Weinstock, J.3
Levitzki, A.4
Burgess, A.W.5
Webster, L.K.6
-
9
-
-
33646044696
-
Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase
-
Ellis AG, Doherty MM, Walker F, Weinstock J, Nerrie M, Vitali A et al. Preclinical analysis of the analinoquinazoline AG1478, a specific small molecule inhibitor of EGF receptor tyrosine kinase. Biochem Pharmacol 2006;71:1422-34.
-
(2006)
Biochem Pharmacol
, vol.71
, pp. 1422-1434
-
-
Ellis, A.G.1
Doherty, M.M.2
Walker, F.3
Weinstock, J.4
Nerrie, M.5
Vitali, A.6
-
10
-
-
34047273010
-
The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers, Implications for combination therapy with monoclonal antibody 806
-
Gan HK, Walker F, Burgess AW, Rigopoulos A, Scott AM, Johns TG. The epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG1478 increases the formation of inactive untethered EGFR dimers. Implications for combination therapy with monoclonal antibody 806. J Biol Chem 2007;282:2840-50.
-
(2007)
J Biol Chem
, vol.282
, pp. 2840-2850
-
-
Gan, H.K.1
Walker, F.2
Burgess, A.W.3
Rigopoulos, A.4
Scott, A.M.5
Johns, T.G.6
-
11
-
-
0035428019
-
Rational design of potent and selective EGFR tyrosine kinase inhibitors as anticancer agents
-
Gosh S, Liu XP, Zheng Y, Uckun FM. Rational design of potent and selective EGFR tyrosine kinase inhibitors as anticancer agents. Curr Cancer Drug Targets 2001;1:129-40.
-
(2001)
Curr Cancer Drug Targets
, vol.1
, pp. 129-140
-
-
Gosh, S.1
Liu, X.P.2
Zheng, Y.3
Uckun, F.M.4
-
12
-
-
4744342856
-
Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation
-
Grøvdal LM, Stang E, Sorkin A, Madshus IH. Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation. Exp Cell Res 2004;300:388-95.
-
(2004)
Exp Cell Res
, vol.300
, pp. 388-395
-
-
Grøvdal, L.M.1
Stang, E.2
Sorkin, A.3
Madshus, I.H.4
-
13
-
-
0041384025
-
Studies of ligand-induced site-specific phosphorylation of epidermal growth factor receptor
-
Guo L, Kozlosky CJ, Ericsson LH, Daniel TO, Cerretti DP, Johnson RS. Studies of ligand-induced site-specific phosphorylation of epidermal growth factor receptor. J Am Soc Mass Spectrom 2003;14:1022-31.
-
(2003)
J Am Soc Mass Spectrom
, vol.14
, pp. 1022-1031
-
-
Guo, L.1
Kozlosky, C.J.2
Ericsson, L.H.3
Daniel, T.O.4
Cerretti, D.P.5
Johnson, R.S.6
-
14
-
-
0029837306
-
Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors
-
Han Y, Caday CG, Nanda A, Cavenee WK, Huang HJ. Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors. Cancer Res 1996;56:3859-61.
-
(1996)
Cancer Res
, vol.56
, pp. 3859-3861
-
-
Han, Y.1
Caday, C.G.2
Nanda, A.3
Cavenee, W.K.4
Huang, H.J.5
-
15
-
-
0023461796
-
A mutant epidermal growth factor receptor with defective protein tyrosine kinase is unable to stimulate proto-oncogene expression and DNA synthesis
-
Honegger AM, Szapary D, Schmidt A, Lyall R, Van Obberghen E, Dull TJ et al. A mutant epidermal growth factor receptor with defective protein tyrosine kinase is unable to stimulate proto-oncogene expression and DNA synthesis. Mol Cell Biol 1987;7:4568-71.
-
(1987)
Mol Cell Biol
, vol.7
, pp. 4568-4571
-
-
Honegger, A.M.1
Szapary, D.2
Schmidt, A.3
Lyall, R.4
Van Obberghen, E.5
Dull, T.J.6
-
16
-
-
33747350713
-
Effect of the anti-receptor ligand-blocking 225 monoclonal antibody on EGF receptor endocytosis and sorting
-
Jaramillo ML, Leon Z, Grothe S, Paul-Roc B, Abulrob A, O'Connor McCourt M. Effect of the anti-receptor ligand-blocking 225 monoclonal antibody on EGF receptor endocytosis and sorting. Exp Cell Res 2006;312:2778-90.
-
(2006)
Exp Cell Res
, vol.312
, pp. 2778-2790
-
-
Jaramillo, M.L.1
Leon, Z.2
Grothe, S.3
Paul-Roc, B.4
Abulrob, A.5
O'Connor McCourt, M.6
-
17
-
-
0037229076
-
Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage
-
Kari C, Chan TO, Rocha de Quadros M, Rodeck U. Targeting the epidermal growth factor receptor in cancer: apoptosis takes center stage. Cancer Res 2003;63:1-5.
-
(2003)
Cancer Res
, vol.63
, pp. 1-5
-
-
Kari, C.1
Chan, T.O.2
Rocha de Quadros, M.3
Rodeck, U.4
-
18
-
-
0029807139
-
Lysosomal targeting of epidermal growth factor receptors via a kinase-dependent pathway is mediated by the receptor carboxyl-terminal residues
-
Kornilova E, Sorkina T, Beguinot L, Sorkin A. Lysosomal targeting of epidermal growth factor receptors via a kinase-dependent pathway is mediated by the receptor carboxyl-terminal residues. J Biol Chem 1996;271:30340-6.
-
(1996)
J Biol Chem
, vol.271
, pp. 30340-30346
-
-
Kornilova, E.1
Sorkina, T.2
Beguinot, L.3
Sorkin, A.4
-
19
-
-
0023618472
-
Compartmentalization dynamics of the epidermal growth factor in A431 cells
-
Kornilova ES, Sorkin AD, Nikolskiy NN. Compartmentalization dynamics of the epidermal growth factor in A431 cells. Tsitologiia 1987;29:904-10.
-
(1987)
Tsitologiia
, vol.29
, pp. 904-910
-
-
Kornilova, E.S.1
Sorkin, A.D.2
Nikolskiy, N.N.3
-
20
-
-
26444523524
-
Enhanced efficacy of radioimmunotherapy with 90Y-CHX-A99-DTPA-hu3S193 by inhibition of epidermal growth factor receptor (EGFR) signaling with EGFR tyrosine kinase inhibitor AG1478
-
Lee FT, Mountain AJ, Kelly MP, Hall C, Rigopoulos A, Johns TG et al. Enhanced efficacy of radioimmunotherapy with 90Y-CHX-A99-DTPA-hu3S193 by inhibition of epidermal growth factor receptor (EGFR) signaling with EGFR tyrosine kinase inhibitor AG1478. Clin Cancer Res 2005;11:7080s-6s.
-
(2005)
Clin Cancer Res
, vol.11
-
-
Lee, F.T.1
Mountain, A.J.2
Kelly, M.P.3
Hall, C.4
Rigopoulos, A.5
Johns, T.G.6
-
21
-
-
0028968949
-
Tyrosine kinase inhibition: an approach to drug development
-
Levitzki A, Gazit A. Tyrosine kinase inhibition: an approach to drug development. Science 1995;267:1782-8.
-
(1995)
Science
, vol.267
, pp. 1782-1788
-
-
Levitzki, A.1
Gazit, A.2
-
22
-
-
0033392493
-
Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1
-
Levkowitz G, Waterman H, Ettenberg SA, Katz M, Tsygankov AY, Alroy I et al. Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1. Mol Cell 1999;4:1029-40.
-
(1999)
Mol Cell
, vol.4
, pp. 1029-1040
-
-
Levkowitz, G.1
Waterman, H.2
Ettenberg, S.A.3
Katz, M.4
Tsygankov, A.Y.5
Alroy, I.6
-
23
-
-
0037018146
-
Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies
-
Longva KE, Blystad FD, Stang E, Larsen AM, Johannessen LE, Madshus IH. Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies. J Cell Biol 2002;156:843-54.
-
(2002)
J Cell Biol
, vol.156
, pp. 843-854
-
-
Longva, K.E.1
Blystad, F.D.2
Stang, E.3
Larsen, A.M.4
Johannessen, L.E.5
Madshus, I.H.6
-
24
-
-
0020628344
-
The role of intermediate vesicles in the adsorptive endocytosis and transport of ligand to lysosomes by human fibroblasts
-
Merion M, Sly WS. The role of intermediate vesicles in the adsorptive endocytosis and transport of ligand to lysosomes by human fibroblasts. J Cell Biol 1983;96:644-50.
-
(1983)
J Cell Biol
, vol.96
, pp. 644-650
-
-
Merion, M.1
Sly, W.S.2
-
25
-
-
0028021551
-
Phosphorylation of the epidermal growth factor receptor during internalization in A-431 cells
-
Nesterov A, Lysan S, Vdovina I, Nikolsky N, Fujita DJ. Phosphorylation of the epidermal growth factor receptor during internalization in A-431 cells. Arch Biochem Biophys 1994;313:351-9.
-
(1994)
Arch Biochem Biophys
, vol.313
, pp. 351-359
-
-
Nesterov, A.1
Lysan, S.2
Vdovina, I.3
Nikolsky, N.4
Fujita, D.J.5
-
26
-
-
52949113842
-
Breast cancer cells with acquired resistance to the EGFR tyrosine kinase inhibitor gefitinib show persistent activation of MAPK signaling
-
Normanno N, Campiglio M, Maiello MR, De Luca, Mancino M, Gallo M et al. Breast cancer cells with acquired resistance to the EGFR tyrosine kinase inhibitor gefitinib show persistent activation of MAPK signaling. Breast Cancer Res Treat 2008;112:25-33
-
(2008)
Breast Cancer Res Treat
, vol.112
, pp. 25-33
-
-
Normanno, N.1
Campiglio, M.2
Maiello, M.R.3
Luca, D.4
Mancino, M.5
Gallo, M.6
-
27
-
-
0028332830
-
Tyrosines 1148 and 1173 of activated human epidermal growth factor receptors are binding sites of Shc in intact cells
-
Okabayashi Y, Kido Y, Okutani T, Sugimoto Y, Sakaguchi K, Kasuga M. Tyrosines 1148 and 1173 of activated human epidermal growth factor receptors are binding sites of Shc in intact cells. J Biol Chem 1994;269:18674-8.
-
(1994)
J Biol Chem
, vol.269
, pp. 18674-18678
-
-
Okabayashi, Y.1
Kido, Y.2
Okutani, T.3
Sugimoto, Y.4
Sakaguchi, K.5
Kasuga, M.6
-
28
-
-
0026793456
-
Growth factor signaling by receptor tyrosine kinases
-
Schlessinger J, Ullrich A. Growth factor signaling by receptor tyrosine kinases. Neuron 1992;9:383-91.
-
(1992)
Neuron
, vol.9
, pp. 383-391
-
-
Schlessinger, J.1
Ullrich, A.2
-
29
-
-
59949101954
-
Inhibiting the function of ABCB1 and ABCG2 by the EGFR tyrosine kinase inhibitor AG1478
-
Shi Z, Tiwari AK, Shukla S, Robey RW, Kim IW, Parmar S et al. Inhibiting the function of ABCB1 and ABCG2 by the EGFR tyrosine kinase inhibitor AG1478. Biochem Pharmacol 2009;77(5):781-93.
-
(2009)
Biochem Pharmacol
, vol.77
, Issue.5
, pp. 781-793
-
-
Shi, Z.1
Tiwari, A.K.2
Shukla, S.3
Robey, R.W.4
Kim, I.W.5
Parmar, S.6
-
30
-
-
0024581749
-
Recycling of epidermal growth factor-receptor complexes in A431 cells
-
Sorkin A, Kornilova E, Teslenko L, Sorokin A, Nikolsky N. Recycling of epidermal growth factor-receptor complexes in A431 cells. Biochim Biophys Acta 1989;1011:88-96.
-
(1989)
Biochim Biophys Acta
, vol.1011
, pp. 88-96
-
-
Sorkin, A.1
Kornilova, E.2
Teslenko, L.3
Sorokin, A.4
Nikolsky, N.5
-
31
-
-
34447283545
-
Effect of combining epidermal growth factor receptor inhibitors and cisplatin on proliferation and apoptosis of oral squamous cell carcinoma cells
-
Takaoka S, Iwase M, Uchida M, Yoshiba S, Kondo G, Watanabe H et al. Effect of combining epidermal growth factor receptor inhibitors and cisplatin on proliferation and apoptosis of oral squamous cell carcinoma cells. Int J Oncol 2007;30:1469-76.
-
(2007)
Int J Oncol
, vol.30
, pp. 1469-1476
-
-
Takaoka, S.1
Iwase, M.2
Uchida, M.3
Yoshiba, S.4
Kondo, G.5
Watanabe, H.6
-
32
-
-
0036787904
-
Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival
-
Wang Y, Pennock S, Chen X, Wang Z. Endosomal signaling of epidermal growth factor receptor stimulates signal transduction pathways leading to cell survival. Mol Cell Biol 2002;22:7279-90.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7279-7290
-
-
Wang, Y.1
Pennock, S.2
Chen, X.3
Wang, Z.4
|