Activation-induced cytidine deaminase splice variants are defective because of the lack of structural support for the catalytic site

Journal of Immunology

Volumn 184, Issue 5, 2010, Pages 2487-2491

  Van Maldegem, Febe ^a   Jibodh, R Aarti ^a   Van Dijk, Remco ^a   Bende, Richard J ^a   Van Noesel, Carel J M ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION INDUCED CYTIDINE DEAMINASE; AMINO ACID; APOLIPOPROTEIN B MESSENGER RNA EDITING ENZYME CATALYTIC POLYPEPTIDE 3G; AICDA (ACTIVATION INDUCED CYTIDINE DEAMINASE); AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); CYTIDINE DEAMINASE; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN;

AMINO ACID SUBSTITUTION; ANALYSIS; ANIMAL CELL; ARTICLE; CATALYSIS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; ENZYME ACTIVE SITE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; STRUCTURE ACTIVITY RELATION; ALTERNATIVE RNA SPLICING; ANIMAL; B LYMPHOCYTE; CELL CULTURE; CELL LINE; CYTOLOGY; FLUORESCENCE MICROSCOPY; GENE REARRANGEMENT; GENETIC RECOMBINATION; GENETICS; IMMUNOLOGY; METABOLISM; MISSENSE MUTATION; MOUSE MUTANT; TUMOR CELL LINE;

ALTERNATIVE SPLICING; ANIMALS; B-LYMPHOCYTES; CATALYTIC DOMAIN; CELL LINE; CELL LINE, TUMOR; CELLS, CULTURED; CYTIDINE DEAMINASE; GREEN FLUORESCENT PROTEINS; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; MICE; MICE, KNOCKOUT; MICROSCOPY, FLUORESCENCE; MUTATION, MISSENSE; RECOMBINANT FUSION PROTEINS; RECOMBINATION, GENETIC;

EID: 77951914086     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0903102     Document Type: Article

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