Homing of mucosal leukocytes to joints: Distinct endothelial ligands in synovium mediate leukocyte-subtype specific adhesion

Journal of Clinical Investigation

Volumn 99, Issue 9, 1997, Pages 2165-2172

  Salmi, Marko ^a,c   Rajala, Pertti ^b   Jalkanen, Sirpa ^a  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b TURKU UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF TURKU   (Finland)

Author keywords

arthritis; inflammation; recirculation; vascular addressins; vascular adhesion protein 1

Indexed keywords

ADDRESSIN; INTERCELLULAR ADHESION MOLECULE 1; PADGEM PROTEIN; VASCULAR CELL ADHESION MOLECULE 1;

ANTIGEN EXPRESSION; ARTHRITIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOTHELIUM; HUMAN; HUMAN CELL; HUMAN TISSUE; LEUKOCYTE ADHERENCE; LIGAND BINDING; LYMPHOCYTE HOMING; MUCOSA; PRIORITY JOURNAL; SYNOVITIS; SYNOVIUM;

EID: 0030922748     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119389     Document Type: Article

References (42)

1. McCarty, D.J., W.J. Koopman, and J.L. Hollander. 1993. Arthritis and allied conditions. A Textbook of Rheumatology. Lea & Febiger, Philadelphia.
2. Butcher, E.C., and L.J. Picker. 1996. Lymphocyte homing and homeostasis. Science (Wash. DC). 272:60-66.
3. Springer, T.A. 1994. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell. 76:301-314.
4. Salmi, M., and S. Jalkanen. 1997. How do lymphocytes know where to go: current concepts and enigmas of lymphocyte homing. Adv. Immunol. 64: In Press.
5. Carlos, T.M., and J.M. Harlan. 1994. Leukocyte-endothelial adhesion molecules. Blood. 84:2068-2101.
6. Jalkanen, S., A.C. Steere, R.I. Fox, and E.C. Butcher. 1986. A distinct endothelial cell recognition system that controls lymphocyte traffic into inflamed synovium. Science (Wash. DC). 233:556-558.
7. Salmi, M., K. Granfors, M. Leirisalo-Repo, M. Hämäläinen, R. MacDermott, R. Leino, T. Havia, and S. Jalkanen. 1992. Selective endothelial binding of interleukin-2-dependent human T-cell lines derived from different tissues. Proc. Natl. Acad. Sci. USA. 89:11436-11440.
8. Salmi, M., D.P. Andrew, E.C. Butcher, and S. Jalkanen. 1995. Dual binding capacity of mucosal immunoblasts to mucosal and synovial endothelium in humans: dissection of the molecular mechanisms. J. Exp. Med. 181:137-149.
9. MacDermott, R.P., M.J. Bragdon, M.K. Jenkins, G.O. Franklin, S. Shedlofsky, and I.J. Kodner. 1981. Human intestinal mononuclear cells. II. Demonstration of naturally occurring subclass of T cells which respond in the allogeneic mixed leukocyte reaction but do not effect cell-mediated lympholysis. Gastroenterology. 80:748-757.
10. Salmi, M., and S. Jalkanen. 1992. A 90-kilodalton endothelial cell molecule mediating lymphocyte binding in humans. Science (Wash. DC). 257:1407-1409.
11. Jalkanen, S., and E.C. Butcher. 1985. In vitro analysis of the homing properties of human lymphocytes: developmental regulation of functional receptors for high endothelial venules. Blood. 66:577-582.
12. Aruffo, A., I. Stamenkovic, M. Melnick, C.B. Underhill, and B. Seed. 1990. CD44 is the principal cell surface receptor for hyaluronate. Cell. 61:1303-1313.
13. Aho, R., S. Jalkanen, and H. Kalimo. 1994. CD44-hyaluronate interaction mediates in vitro lymphocyte binding to the white matter of the central nervous system. J. Neuropathol. Exp. Neurol. 53:295-302.
14. Wells, A.F., E. Larsson, A. Tengblad, B. Fellström, G. Tufveson, L. Klaereskog, and T.C. Laurent. 1990. The localization of hyaluronan in normal and rejected human kidneys. Transplantation (Baltimore). 50:240-243.
15. Picker, L.J., and E.G. Butcher. 1992. Physiological and molecular mechanisms of lymphocyte homing. Annu. Rev. Immunol. 10:561-591.
16. van Dinther-Janssen, A.C.H.M., E. Horst, G. Koopman, W. Newmann, R.J. Scheper, C.J.L.M. Meijer, and S.T. Pals. 1991. The VLA-4/VCAM-1 pathway is involved in lymphocyte adhesion to endothelium in rheumatoid synovium. J. Immunol. 147:4207-4210.
17. Grober, J.S., B.L. Brown, H. Ebling, B. Athey, C.B. Thompson, D.A. Fox, and L.M. Stoolman. 1993. Monocyte-endothelial adhesion in chronic rheumatoid arthritis. In situ detection of selectin and integrin-dependent interactions. J. Clin. Invest. 91:2609-2619.
18. Fischer, C., H.-G. Thiele, and A. Hamann. 1993. Lymphocyte-endothelial interactions in inflamed synovia: involvement of several adhesion molecules and integrin epitopes. Scand. J. Immunol. 38:158-166.
19. Michie, S.A., P.R. Streeter, P.A. Bolt, E.C. Butcher, and L.J. Picker. 1993. The human peripheral lymph node vascular addressin. An inducible endothelial antigen involved in lymphocyte homing. Am. J. Pathol. 143:1688-1698.
20. El-Gabalawy, H., M. Gallatin, R. Vazeux, G. Peterman, and J . Wilkins. 1994. Expression of ICAM-R (ICAM-3), a novel counter-receptor for LFA-1, in rheumatoid and nonrheumatoid synovium. Comparison with other adhesion molecules. Arthritis Rheum. 37:846-854.
21. Koch, A.E., J.C. Burrows, G.K. Haines, T.M. Carlos, J.M. Harlan, and S.J. Leibovich. 1991. Immunolocalization of endothelial and leukocyte adhesion molecules in human rheumatoid and osteoarthritic synovial tissues. Lab. Invest. 64:313-320.
22. 1 integrin (VLA-4) ligands in arthritis. Vascular cell adhesion molecule-1 expression in synovium and on fibroblast-like synoviocytes. J. Immunol. 149:1424-1431.
23. 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences. J. Immunol. 156:2851-2857.
24. McEver, R.E., K.L. Moore, and R.D. Cummings. 1995. Leukocyte trafficking mediated by selectin-carbohydrate interactions. J. Biol. Chem. 270: 11025-11028.
25. Steere, A.C., P.H. Duray, and E.C. Butcher. 1988. Spirochetal antigens and lymphoid cell surface markers in Lyme synovitis. Comparison with rheumatoid synovium and tonsillar lymphoid tissue. Arthritis Rheum. 31:487-495.
26. Leirisalo-Repo, M., and H. Suoranta. 1988. Ten-year follow-up study of patients with Yersinia arthritis. Arthritis Rheum. 31:533-537.
27. Mielants, H., and E.M. Veys. 1990. The gut in the spondyloarthropathies. J. Rheumatol. 17:7-10.
28. Mielants, H., E.M. Veys, C. Cuvelier, M. De Vos, S. Goemaere, M. Maertens, and R. Joos. 1993. Gut inflammation in children with late onset pauciarticular juvenile chronic arthritis and evolution to adult spondyloarthropathy - a prospective study. J. Rheumatol. 20:1567-1572.
29. Leirisalo-Repo, M., U. Turunen, S. Stenman, P. Helenius, and K. Seppälä. 1994. High frequency of silent inflammatory bowel disease in spondylar-thropathy. Arthritis Rheum. 37:23-31.
30. Starzl, T.E., R. Weil III, L.J. Koep, R.T. McCalmon, P.I. Terasaki, Y. Iwaki, G.P.J. Schröter, J.J. Franks, V. Subryan, and C.G. Halgrimson. 1979. Thoracic duct fistula and renal transplantation. Ann. Surg. 190:74-486.
31. Randolph, G.W., and M.B. Furie. 1996. Mononuclear phagocytes egress from an in vitro model of the vascular wall by migrating across endothelium in the basal to apical direction: role of intercellular adhesion molecule 1 and the CD11/CD18 integrins. J. Exp. Med. 183:451-462.
32. Weller, A., S. Isenmann, and D. Vestweber. 1992. Cloning of the mouse endothelial selectins. Expression of both E-and P-selectin is inducible by tumor necrosis factor α. J. Biol. Chem. 267:15176-15183.
33. + T lymphocytes on tumor necrosis factor α-activated vascular endothelium under flow. J. Exp. Med. 181:1179-1186.
34. Kavanaugh, A.F., L.S. Davis, L.A. Nichols, S.H. Norris, R. Rothlein, L.A. Scharschmidt, and P.E. Lipsky. 1994. Treatment of refractory rheumatoid arthritis with a monoclonal antibody to intercellular adhesion molecule 1. Arthritis Rheum. 37:992-999.
35. Mikecz, K., F.R. Brennan, J.H. Kim, and T.T. Glant. 1995. Anti-CD44 treatment abrogates tissue oedema and leukocyte infiltration in murine arthritis. Nat. Med. 1:558-563.
36. Issekutz, T.B. 1995. Leukocyte adhesion and the anti-inflammatory effects of leukocyte integrin blockade. Agents Actions Suppl. 46:85-96.
37. Wellicome, S.M., M.H. Thornhill, C. Pitzalis, D.S. Thomas, J.S.S. Lanchbury, G.S. Panayi, and D.O. Haskard. 1990. A monoclonal antibody that detects a novel antigen on endothelial cells that is induced by tumor necrosis factor, IL-1, or lipopolysaccharide. J. Immunol. 144:2558-2565.
38. Streeter, P.R., B.T.N. Rouse, and E.C. Butcher. 1988. Immunohistologic and functional characterization of a vascular addressin involved in lymphocyte homing into peripheral lymph nodes. J. Cell Biol. 107:1853-1862.
39. Airas, L., M. Salmi, and S. Jalkanen. 1993. Lymphocyte-vascular adhesion protein-2 is a novel 70-kDa molecule involved in lymphocyte adhesion to vascular endothelium. J. Immunol. 151:4228-4238.
40. de Fougerolles, A.R., S.A. Stacker, R. Schwarting, and T.A. Springer. 1991. Characterization of ICAM-2 and evidence for a third counter-receptor for LFA-1. J. Exp. Med. 174:253-267.
41. Parham, P. 1981. Monoclonal antibodies against two separate alloantigenic sites of HLA-B40. Immunogenetics. 13:509-527.
42. Coffman, R.L., and I.L. Weissman. 1981. B220: a B cell specific number of the T200 glycoprotein family. Nature (Lond.). 289:681-683.