Anti-inflammatory effects of LJP 1586 [Z-3-fluoro-2-(4-methoxybenzyl) allylamine hydrochloride], an amine-based inhibitor of semicarbazide-sensitive amine oxidase activity

Journal of Pharmacology and Experimental Therapeutics

Volumn 324, Issue 2, 2008, Pages 867-875

  O'Rourke, Anne M ^a   Wang, Eric Y ^a   Miller, Andrew ^a   Podar, Erika M ^a   Scheyhing, Kelly ^a   Huang, Li ^a   Kessler, Christina ^a   Gao, Hongfeng ^a   Ton Nu, Huong Thu ^a   MacDonald, Mary T ^a   Jones, David S ^a   Linnik, Matthew D ^a  

^a La Jolla Pharmaceutical Company   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 FLUORO 2 (4 METHOXYBENZYL)ALLYLAMINE; AMINE OXIDASE (COPPER CONTAINING); AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; ANTIINFLAMMATORY AGENT; LIPOPOLYSACCHARIDE; LJP 1586; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG HALF LIFE; DRUG MECHANISM; DRUG POTENCY; DRUG SPECIFICITY; DRUG STRUCTURE; ENZYME ACTIVITY; FEMALE; LUNG LAVAGE; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; RAT;

ALLYLAMINE; AMINE OXIDASE (COPPER-CONTAINING); AMINES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHO CELLS; CRICETINAE; CRICETULUS; ENZYME INHIBITORS; FEMALE; HUMANS; INFLAMMATION; LUNG; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; RATS; RATS, SPRAGUE-DAWLEY;

EID: 38749108448     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.107.131672     Document Type: Article

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