Backbone resonance assignments of a promiscuous aminoglycoside antibiotic resistance enzyme; The aminoglycoside phosphotransferase(3′)-IIIa

Biomolecular NMR Assignments

Volumn 4, Issue 1, 2010, Pages 9-12

  Serpersu, Engin H ^a   Özen, Can ^b   Norris, Adrianne L ^a   Steren, Carlos ^a   Whittemore, Neil ^a  

^a UNIVERSITY OF TENNESSEE   (United States)

^b MIDDLE EAST TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Aminoglycoside; Antibiotic resistance; Assignments; Backbone resonance; Phosphotransferase; Promiscuous enzyme

Indexed keywords

BACTERIAL PROTEIN; KANAMYCIN KINASE;

ARTICLE; CHEMISTRY; HUMAN; NUCLEAR MAGNETIC RESONANCE;

BACTERIAL PROTEINS; HUMANS; KANAMYCIN KINASE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR;

BACTERIA (MICROORGANISMS);

EID: 77951879659     PISSN: 18742718     EISSN: 1874270X     Source Type: Journal    
DOI: 10.1007/s12104-009-9195-z     Document Type: Article

References (10)

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7. C Özen EH Serpersu 2004 Thermodynamics of aminoglycoside binding to aminoglycoside-3′-phosphotransferase IIIa studied by isothermal titration calorimetry Biochemistry 43 14667 14675 10.1021/bi0487286 (Pubitemid 39524941)
8. C Özen JM Malek EH Serpersu 2006 Dissection of aminoglycoside-enzyme interactions: a calorimetric and NMR study of neomycin B binding to the aminoglycoside phosphotransferase(3′)-IIIa J Am Chem Soc 128 15248 15254 10.1021/ja0643220 (Pubitemid 44853536)
9. C Özen AL Norris M Land E Tjioe EH Serpersu 2008 Detection of specific solvent rearrangement regions of an enzyme: NMR, ITC studies with aminoglycoside phosphotransferase(3′)-IIIa Biochemistry 47 40 49 10.1021/bi701711j
10. Y Shen A Bax 2007 Protein backbone chemical shifts predicted from searching a database for torsion angle and sequence homology J Biomol NMR 38 289 302 10.1007/s10858-007-9166-6 (Pubitemid 47108511)