Impact of culture media glucose levels on the intestinal uptake of organic cations

Cytotechnology

Volumn 62, Issue 1, 2010, Pages 23-29

  Faria, Ana ^a,b   Monteiro, Rosário ^a   Pestana, Diogo ^a   Martel, Fátima ^a   De Freitas, Victor ^b   Mateus, Nuno ^b   Calhau, Conceição ^a  

^a University of Porto   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

Author keywords

Absorption; Caco 2 cells; Glucose; Intestinal epithelium; Organic cations; Transport

Indexed keywords

GLUCOSE; ORGANIC CATION TRANSPORTER 1; ORGANIC CATION TRANSPORTER 3;

ARTICLE; BINDING AFFINITY; CELL CULTURE; CELL STRAIN CACO 2; CONTROLLED STUDY; CULTURE MEDIUM; GENE EXPRESSION; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; INTESTINE ABSORPTION;

EID: 77951877830     PISSN: 09209069     EISSN: 15730778     Source Type: Journal    
DOI: 10.1007/s10616-010-9257-1     Document Type: Article

References (34)

1. SA Adibi 2003 Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease Am J Physiol Gastrointest Liver Physiol 285 G779 G788 1:CAS:528:DC%2BD3sXpt1Kju7k%3D
2. P Artursson 1991 Cell cultures as models for drug absorption across the intestinal mucosa Crit Rev Ther Drug Carrier Syst 8 305 330 1:CAS:528: DyaK38XnsFGmtQ%3D%3D
3. P Artursson J Karlsson 1991 Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells Biochem Biophys Res Commun 175 880 885 10.1016/0006-291X(91)91647-U 1:CAS:528:DyaK3MXhslOrt7c%3D
4. TK Basu C Basualdo 1997 Vitamin A homeostasis and diabetes mellitus Nutrition 13 804 806 10.1016/S0899-9007(97)00192-5 1:CAS:528:DyaK2sXmt1SrsLc%3D (Pubitemid 27382450)
5. MM Bradford 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248 254 10.1016/0003-2697(76)90527-3 1:CAS:528: DyaE28XksVehtrY%3D
6. JR Burgoyne M Madhani F Cuello RL Charles JP Brennan E Schroder DD Browning P Eaton 2007 Cysteine redox sensor in PKGIa enables oxidant-induced activation Science 317 1393 1397 10.1126/science.1144318 1:CAS:528: DC%2BD2sXpvFWmu7s%3D (Pubitemid 47417480)
7. R Carratu M Secondulfo L de Magistris D Iafusco A Urio MG Carbone G Pontoni M Carteni F Prisco 1999 Altered intestinal permeability to mannitol in diabetes mellitus type I J Pediatr Gastroenterol Nutr 28 264 269 10.1097/00005176-199903000-00010 1:CAS:528:DyaK1MXotVShurg%3D (Pubitemid 29293647)
8. DM Casirola RR Vinnakota RP Ferraris 1994 Intestinal amino acid transport in mice is modulated by diabetes and diet J Nutr 124 842 852 1:CAS:528:DyaK2cXktleqt7o%3D
9. R Contreras O Fuentes GE Mann L Sobrevia 1997 Diabetes and insulin-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glands J Physiol 498 Pt 3 787 796 1:CAS:528:DyaK2sXhsFeiu78%3D
10. EM Cornford S Hyman ME Cornford M Clare-Salzler 1995 Down-regulation of blood-brain glucose transport in the hyperglycemic nonobese diabetic mouse Neurochem Res 20 869 873 10.1007/BF00969700 1:CAS:528:DyaK2MXns1Smtbs%3D
11. VM D'Souza DJ Buckley AR Buckley GM Pauletti 2003 Extracellular glucose concentration alters functional activity of the intestinal oligopeptide transporter (PepT-1) in Caco-2 cells J Pharm Sci 92 594 603 10.1002/jps.10325 (Pubitemid 36258974)
12. F Delie W Rubas 1997 A human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: advantages and limitations of the Caco-2 model Crit Rev Ther Drug Carrier Syst 14 221 286 1:CAS:528:DyaK2sXlvFeru7c%3D
13. A Faria N Mateus V de Freitas C Calhau 2006 Modulation of MPP + uptake by procyanidins in Caco-2 cells: involvement of oxidation/reduction reactions FEBS Lett 580 155 160 10.1016/j.febslet.2005.11.068 1:CAS:528:DC%2BD28XkslKm (Pubitemid 43005329)
14. G Giannico P Cortes MH Baccora C Hassett DW Taube J Yee 2007 Glibenclamide prevents increased extracellular matrix formation induced by high glucose concentration in mesangial cells Am J Physiol Renal Physiol Physiol 292 F57 F65 10.1152/ajprenal.00210.2006 1:CAS:528:DC%2BD2sXisFGhsbc%3D (Pubitemid 46105243)
15. P Goncalves JR Araujo F Martel 2008 The effect of high glucose on SERT, the human plasmalemmal serotonin transporter Nutr Neurosci 11 244 250 10.1179/147683008X344156 1:CAS:528:DC%2BD1MXlsFyiurs%3D
16. D Grundemann B Schechinger GA Rappold E Schomig 1998 Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter Nat Neurosci 1 349 351 10.1038/1557 1:CAS:528:DyaK1MXitVCgt7Y%3D
17. H Ha HB Lee 2000 Reactive oxygen species as glucose signaling molecules in mesangial cells cultured under high glucose Kidney Int Suppl 77 S19 S25 10.1046/j.1523-1755.2000.07704.x 1:CAS:528:DC%2BD3cXms1Oiurs%3D
18. T Hahn S Barth U Weiss W Mosgoeller G Desoye 1998 Sustained hyperglycemia in vitro down-regulates the GLUT1 glucose transport system of cultured human term placental trophoblast: a mechanism to protect fetal development? Faseb J 12 1221 1231 1:CAS:528:DyaK1cXlvFWku7g%3D
19. Hardman J, Limbird L, Molinoff P, Ruddon R, Gilman A (2002) Goodman and Gilman's, The pharmacological basis of therapeutics. McGraw-Hill, New York
20. M Hayer H Bonisch M Bruss 1999 Molecular cloning, functional characterization and genomic organization of four alternatively spliced isoforms of the human organic cation transporter 1 (hOCT1/SLC22A1) Ann Hum Genet 63 473 482 10.1046/j.1469-1809.2000.6430267.x 1:STN:280:DC%2BD3Mzhs1Wltw%3D%3D
21. M Hayer-Zillgen M Bruss H Bonisch 2002 Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3 Br J Pharmacol 136 829 836 10.1038/sj.bjp.0704785 1:CAS:528:DC%2BD38XlvV2rurk%3D (Pubitemid 34836857)
22. IJ Hidalgo TJ Raub RT Borchardt 1989 Characterization of the human colon carcinoma cell line (Caco-2) as a model system for intestinal epithelial permeability Gastroenterology 96 736 749 1:STN:280:DyaL1M7itFeqsg%3D%3D
23. N Kimura S Masuda T Katsura K Inui 2009 Transport of guanidine compounds by human organic cation transporters, hOCT1 and hOCT2 Biochem Pharmacol 77 1429 1436 10.1016/j.bcp.2009.01.010 1:CAS:528:DC%2BD1MXjsFSgs78%3D
24. H Lennernas 1997 Human jejunal effective permeability and its correlation with preclinical drug absorption models J Pharm Pharmacol 49 627 638 1:STN:280:DyaK2szpvFKjsQ%3D%3D
25. F Martel C Calhau I Azevedo 2000 Characterization of the transport of the organic cation [3H]MPP + in human intestinal epithelial (Caco-2) cells Naunyn Schmiedebergs Arch Pharmacol 361 505 513 10.1007/s002100000223 1:CAS:528:DC%2BD3cXivFGjur8%3D (Pubitemid 30262599)
26. F Martel D Grundemann C Calhau E Schomig 2001 Apical uptake of organic cations by human intestinal Caco-2 cells: putative involvement of ASF transporters Naunyn Schmiedebergs Arch Pharmacol 363 40 49 10.1007/s002100000335 1:CAS:528:DC%2BD3MXitVyisQ%3D%3D (Pubitemid 32060085)
27. J Muller KS Lips L Metzner RH Neubert H Koepsell M Brandsch 2005 Drug specificity and intestinal membrane localization of human organic cation transporters (OCT) Biochem Pharmacol 70 1851 1860 10.1016/j.bcp.2005.09.011 (Pubitemid 41612016)
28. H Naggar MS Ola P Moore W Huang CC Bridges V Ganapathy SB Smith 2002 Downregulation of reduced-folate transporter by glucose in cultured RPE cells and in RPE of diabetic mice Invest Ophthalmol Vis Sci 43 556 563
29. I Noyman M Marikovsky S Sasson AH Stark K Bernath R Seger Z Madar 2002 Hyperglycemia reduces nitric oxide synthase and glycogen synthase activity in endothelial cells Nitric Oxide 7 187 193 10.1016/S1089-8603(02)00106-4 1:CAS:528:DC%2BD38Xns12gsbk%3D (Pubitemid 35346223)
30. Y Sambuy I De Angelis G Ranaldi ML Scarino A Stammati F Zucco 2005 The Caco-2 cell line as a model of the intestinal barrier: influence of cell and culture-related factors on Caco-2 cell functional characteristics Cell Biol Toxicol 21 1 26 10.1007/s10565-005-0085-6 1:STN:280:DC%2BD2M3jtFGmtw%3D%3D (Pubitemid 40767684)
31. HP Schedl KK Christensen WC Ronnenberg 1995 Effects of diabetes on calcium uptake by rat brush border membrane vesicles Clin Exp Pharmacol Physiol 22 272 276 10.1111/j.1440-1681.1995.tb01993.x 1:CAS:528:DyaK2MXlslGmu7k%3D
32. MJ Stevens Y Hosaka JA Masterson SM Jones TP Thomas DD Larkin 1999 Downregulation of the human taurine transporter by glucose in cultured retinal pigment epithelial cells Am J Physiol 277 E760 E771 1:CAS:528:DyaK1MXntFCjtLg%3D
33. AB Thomson G Wild 1997 Adaptation of intestinal nutrient transport in health and disease. Part II Dig Dis Sci 42 470 488 10.1023/A:1018874404762 1:STN:280:DyaK2s3isFymtQ%3D%3D (Pubitemid 27148330)
34. S Yee 1997 In vitro permeability across Caco-2 cells (colonic) can predict in vivo (small intestinal) absorption in man-fact or myth Pharm Res 14 763 766 10.1023/A:1012102522787 1:CAS:528:DyaK2sXkt1yit7c%3D (Pubitemid 27281671)