Relationship of strain-dependent susceptibility to experimentally induced acute pancreatitis with regulation of Prss1 and Spink3 expression

Laboratory Investigation

Volumn 90, Issue 5, 2010, Pages 654-664

  Wang, Jun ^a   Ohmuraya, Masaki ^a   Suyama, Koichi ^a   Hirota, Masahiko ^a   Ozaki, Nobuyuki ^a   Baba, Hideo ^a   Nakagata, Naomi ^a   Araki, Kimi ^a   Yamamura, Ken Ichi ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

1 (Prss1); Kazal type 3 (Spink3); Proteinase; Serine; Serine protease inhibitor; Single nucleotide polymorphisms (SNPs)

Indexed keywords

CERULETIDE; CHOLINE; ETHIONINE; PROTEIN; PROTEIN PRSS1; PROTEIN SPINK3; UNCLASSIFIED DRUG;

ACUTE PANCREATITIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; GENETIC SUSCEPTIBILITY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; STRAIN DIFFERENCE;

ACUTE DISEASE; ANIMALS; BASE SEQUENCE; BLOTTING, NORTHERN; BLOTTING, WESTERN; CAERULEIN; DIET; GENE EXPRESSION; GENETIC PREDISPOSITION TO DISEASE; GLYCOPROTEINS; MICE; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, INBRED CBA; MOLECULAR SEQUENCE DATA; PANCREATITIS; PROSTATIC SECRETORY PROTEINS; SEQUENCE HOMOLOGY, NUCLEIC ACID; SEVERITY OF ILLNESS INDEX; SPECIES SPECIFICITY; TRYPSIN;

EID: 77951785123     PISSN: 00236837     EISSN: 15300307     Source Type: Journal    
DOI: 10.1038/labinvest.2010.44     Document Type: Article

References (44)

1. Beck JA, Lloyd S, Hafezparast M, et al. Genealogies of mouse inbred strains. Nat Genet 2000;24:23-25.
2. Moore KJ. Utilization of mouse models in the discovery of human disease genes. Drug Discov Today 1999;4:123-128.
3. Yonekawa H, Moriwaki K, Gotoh O, et al. Hybrid origin of Japanese mice 'Mus musculus molossinus': evidence from restriction analysis of mitochondrial DNA. Mol Biol Evol 1988;5:63-78.
4. Prager EM, Orrego C, Sage RD. Genetic variation and phylogeography of central Asian and other house mice, including a major new mitochondrial lineage in Yemen. Genetics 1998;150:835-861.
5. Wade CM, Kulbokas III EJ, Kirby AW, et al. The mosaic structure of variation in the laboratory mouse genome. Nature 2002;420:574-578.
6. Sakai T, Miura I, Yamada-Ishibashi S, et al. Update of mouse microsatellite database of Japan (MMDBJ). Exp Anim 2004;53:151-154.
7. Abe K, Noguchi H, Tagawa K, et al. Contribution of Asian mouse subspecies Mus musculus molossinus to genomic constitution of strain C57BL/6J, as defined by BAC-end sequence-SNP analysis. Genome Res 2004;14:2439-2447.
8. Jansa P, Divina P, Forejt J. Construction and characterization of a genomic BAC library for the Mus m. musculus mouse subspecies (PWD/Ph inbred strain). BMC Genomics 2005;6:161.
9. Moriwaki K. Wild mouse from geneticist's viewpoint. In: Moriwaki K, Shiroishi T, Yonekawa H (eds). Genetics in Wild Mice: Its Application to Biomedical Research. Japan Scientific Press/Karger: Tokyo, 1994, pp xiii-xxiv.
10. Koide T, Moriwaki K, Uchida K, et al. A new inbred strain JF1 established from Japanese fancy mouse carrying the classic piebald allele. Mamm Genome 1998;9:15-19.
11. Surwit RS, Kuhn CM, Cochrane C, et al. Diet-induced type II diabetes in C57BL/6J mice. Diabetes 1988;37:1163-1167.
12. Kobayashi M, Ohno T, Tsuchiya T, et al. Characterization of diabetes-related traits in MSM and JF1 mice on high-fat diet. J Nutr Biochem 2004;15:614-621.
13. Gukovskaya AS, Hosseini S, Satoh A, et al. Ethanol differentially regulates NF-kappaB activation in pancreatic acinar cells through calcium and protein kinase C pathways. Am J Physiol Gastrointest Liver Physiol 2004;286:G204-G213.
14. Pandol SJ. Acute pancreatitis. Curr Opin Gastroenterol 2005;21: 538-543.
15. Satoh A, Gukovskaya AS, Reeve Jr JR, et al. Ethanol sensitizes NF-kappaB activation in pancreatic acinar cells through effects on protein kinase C-epsilon. Am J Physiol Gastrointest Liver Physiol 2006;291:G432-G438.
16. Schenker S, Montalvo R. Alcohol and the pancreas. Recent Dev Alcohol 1998;14:41-65.
17. Acosta JM, Ledesma CL. Gallstone migration as a cause of acute pancreatitis. N Engl J Med 1974;290:484-487.
18. Lerch MM, Hernandez CA, Adler G. Gallstones and acute pancreatitis-mechanisms and mechanics. Dig Dis 1994;12:242-247.
19. Rosendahl J, Bodeker H, Mossner J, et al. Hereditary chronic pancreatitis. Orphanet J Rare Dis 2007;2:1.
20. Hirota M, Ohmuraya M, Baba H. Genetic background of pancreatitis. Postgrad Med J 2006;82:775-778.
21. Whitcomb DC, Gorry MC, Preston RA, et al. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet 1996;14:141-145.
22. Varallyay E, Pal G, Patthy A, et al. Two mutations in rat trypsin confer resistance against autolysis. Biochem Biophys Res Commun 1998;243:56-60.
23. Witt H, Luck W, Hennies HC, et al. Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet 2000;25:213-216.
24. Ohmuraya M, Hirota M, Araki K, et al. Enhanced trypsin activity in pancreatic acinar cells deficient for serine protease inhibitor kazal type 3. Pancreas 2006;33:104-106.
25. Hashimoto D, Ohmuraya M, Hirota M, et al. Involvement of autophagy in trypsinogen activation within the pancreatic acinar cells. J Cell Biol 2008;181:1065-1072.
26. Ohmuraya M, Yamamura K. Autophagy and acute pancreatitis: a novel autophagy theory for trypsinogen activation. Autophagy 2008;4: 1060-1062.
27. Rosendahl J, Witt H, Szmola R, et al. Chymotrypsin C (CTRC) variants that diminish activity or secretion are associated with chronic pancreatitis. Nat Genet 2008;40:78-82.
28. Lombardi B, Estes LW, Longnecker DS. Acute hemorrhagic pancreatitis (massive necrosis) with fat necrosis induced in mice by DL-ethionine fed with a choline-deficient diet. Am J Pathol 1975;79:465-480.
29. Schmidt J, Lewandrowski K, Fernandez-del Castillo C, et al. Histopathologic correlates of serum amylase activity in acute experimental pancreatitis. Dig Dis Sci 1992;37:1426-1433.
30. Nishimori I, Kamakura M, Fujikawa-Adachi K, et al. Mutations in exons 2 and 3 of the cationic trypsinogen gene in Japanese families with hereditary pancreatitis. Gut 1999;44:259-263.
31. Boulet AM, Erwin CR, Rutter WJ. Cell-specific enhancers in the rat exocrine pancreas. Proc Natl Acad Sci USA 1986;83:3599-3603.
32. Cockell M, Stevenson BJ, Strubin M, et al. Identification of a cell-specific DNA-binding activity that interacts with a transcriptional activator of genes expressed in the acinar pancreas. Mol Cell Biol 1989;9: 2464-2476.
33. Roux E, Strubin M, Hagenbuchle O, et al. The cell-specific transcription factor PTF1 contains two different subunits that interact with the DNA. Genes Dev 1989;3:1613-1624.
34. Stevenson BJ, Hagenbuchle O, Wellauer PK. Sequence organisation and transcriptional regulation of the mouse elastase II and trypsin genes. Nucleic Acids Res 1986;14:8307-8330.
35. Swift GH, Hammer RE, MacDonald RJ, et al. Tissue-specific expression of the rat pancreatic elastase I gene in transgenic mice. Cell 1984;38:639-646.
36. Yasuda T, Ohmachi Y, Katsuki M, et al. Identification of novel pancreas-specific regulatory sequences in the promoter region of human pancreatic secretory trypsin inhibitor gene. J Biol Chem 1998;273:34413-34421.
37. Howard G, Keller PR, Johnson TM, et al. Binding of a pancreatic nuclear protein is correlated with amylase enhancer activity. Nucleic Acids Res 1989;17:8185-8195.
38. Chen SH, Estes LW, Lombardi B. Lecithin depletion in hepatic microsomal membranes of rats fed on a choline-deficient diet. Exp Mol Pathol 1972;17:176-186.
39. Leelavathi DE, Katyal SL, Lombardi B. Lecithin depletion in liver mitochondria of rats fed a choline-deficient diet. Effect on beta-hydroxybutyrate dehydrogenase. Life Sci 1974;14:1203-1210.
40. Lombardi B. Effects of choline deficiency on rat hepatocytes. Fed Proc 1971;30:139-142.
41. Howes N, Greenhalf W, Stocken DD, et al. Cationic trypsinogen mutations and pancreatitis. Clin Lab Med 2005;25:39-59.
42. O'Reilly DA, Kingsnorth AN. Hereditary pancreatitis and mutations of the cationic trypsinogen gene. Br J Surg 2000;87:708-717.
43. Guerassimov A, Hoshino Y, Takubo Y, et al. The development of emphysema in cigarette smoke-exposed mice is strain dependent. Am J Respir Crit Care Med 2004;170:974-980.
44. Shapiro SD. Animal models for chronic obstructive pulmonary disease: age of klotho and marlboro mice. Am J Respir Cell Mol Biol 2000; 22:4-7.