메뉴 건너뛰기




Volumn 74, Issue 5, 2010, Pages 916-924

Myocardial transfection of hypoxia inducible factor-1α via an adenoviral vector during coronary artery bypass grafting - A multicenter phase I and safety study

Author keywords

Aortocoronary bypass; Coronary angiogenesis; HIF 1 ; Viral transfection

Indexed keywords

ADENOVIRUS VECTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PLACEBO; SODIUM CHLORIDE;

EID: 77951738011     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-09-0594     Document Type: Article
Times cited : (37)

References (26)
  • 1
    • 0030807192 scopus 로고    scopus 로고
    • The burden of cardiovascular diseases mortality in Europe: Task force of the European Society of Cardiology on cardiovascular mortality and morbidity statistics in Europe
    • Sans S, Kesteloot H, Kromhout D. The burden of cardiovascular diseases mortality in Europe: Task force of the European Society of Cardiology on cardiovascular mortality and morbidity statistics in Europe. Eur Heart J 1997; 18: 1231-1248.
    • (1997) Eur Heart J , vol.18 , pp. 1231-1248
    • Sans, S.1    Kesteloot, H.2    Kromhout, D.3
  • 2
    • 0029784101 scopus 로고    scopus 로고
    • The importance of completeness of revascularization during long-term follow-up after coronary artery operations
    • Jones EL, Weintraub WS. The importance of completeness of revascularization during long-term follow-up after coronary artery operations. J Thorac Cardiovasc Surg 1996; 112: 227-237.
    • (1996) J Thorac Cardiovasc Surg , vol.112 , pp. 227-237
    • Jones, E.L.1    Weintraub, W.S.2
  • 3
    • 0020068764 scopus 로고
    • Incomplete myocardial reperfusion despite a patent coronary bypass: A generally unrecognized shortcoming of the surgical approach to coronary artery disease
    • Levin DC, Beckmann CF, Sos TA, Sniderman K. Incomplete myocardial reperfusion despite a patent coronary bypass: A generally unrecognized shortcoming of the surgical approach to coronary artery disease. Radiology 1982; 142: 317-321.
    • (1982) Radiology , vol.142 , pp. 317-321
    • Levin, D.C.1    Beckmann, C.F.2    Sos, T.A.3    Sniderman, K.4
  • 4
    • 0033619428 scopus 로고    scopus 로고
    • Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: The PREVENT single-centre, randomised, controlled trial
    • Mann MJ, Whittemore AD, Donaldson MC, Belkin M, Conte MS, Polak JF, et al. Ex-vivo gene therapy of human vascular bypass grafts with E2F decoy: The PREVENT single-centre, randomised, controlled trial. Lancet 1999; 354: 1493-1498.
    • (1999) Lancet , vol.354 , pp. 1493-1498
    • Mann, M.J.1    Whittemore, A.D.2    Donaldson, M.C.3    Belkin, M.4    Conte, M.S.5    Polak, J.F.6
  • 5
    • 0028116874 scopus 로고
    • Intramuscular administration of vascular endothelial growth factor induces dose-dependent collateral artery augmentation in a rabbit model of chronic limb ischemia
    • II-228-II-234
    • Takeshita S, Pu LQ, Stein LA, Sniderman AD, Bunting S, Ferrara N, et al. Intramuscular administration of vascular endothelial growth factor induces dose-dependent collateral artery augmentation in a rabbit model of chronic limb ischemia. Circulation 1994; 90: II-228-II-234.
    • (1994) Circulation , vol.90
    • Takeshita, S.1    Pu, L.Q.2    Stein, L.A.3    Sniderman, A.D.4    Bunting, S.5    Ferrara, N.6
  • 6
    • 0028098738 scopus 로고
    • Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts
    • Harada K, Grossman W, Friedman M, Edelman ER, Prasad PV, Keighley CS, et al. Basic fibroblast growth factor improves myocardial function in chronically ischemic porcine hearts. J Clin Invest 1994; 94: 623-630.
    • (1994) J Clin Invest , vol.94 , pp. 623-630
    • Harada, K.1    Grossman, W.2    Friedman, M.3    Edelman, E.R.4    Prasad, P.V.5    Keighley, C.S.6
  • 7
    • 69549116027 scopus 로고    scopus 로고
    • Treatment with recombinant placental growth factor (PIGF) enhances both angiogenesis and arteriogenesis and improves survival after myocardial infarction
    • Takeda Y, Uemura S, Iwama H, Imagawa K, Nishida T, Onoue K, et al. Treatment with recombinant placental growth factor (PIGF) enhances both angiogenesis and arteriogenesis and improves survival after myocardial infarction. Circ J 2009; 73: 1674-1682.
    • (2009) Circ J , vol.73 , pp. 1674-1682
    • Takeda, Y.1    Uemura, S.2    Iwama, H.3    Imagawa, K.4    Nishida, T.5    Onoue, K.6
  • 8
    • 0029958320 scopus 로고    scopus 로고
    • Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo
    • Takeshita S, Tsurumi Y, Couffinahl T, Asahara T, Bauters C, Symes J, et al. Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo. Lab Invest 1996; 75: 487-501.
    • (1996) Lab Invest , vol.75 , pp. 487-501
    • Takeshita, S.1    Tsurumi, Y.2    Couffinahl, T.3    Asahara, T.4    Bauters, C.5    Symes, J.6
  • 9
    • 0031940012 scopus 로고    scopus 로고
    • Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart
    • Mack CA, Patel SR, Schwarz EA, Zanzonico P, Hahn RT, Ilercil A, et al. Biologic bypass with the use of adenovirus-mediated gene transfer of the complementary deoxyribonucleic acid for vascular endothelial growth factor 121 improves myocardial perfusion and function in the ischemic porcine heart. J Thorac Cardiovasc Surg 1998; 115: 168-176.
    • (1998) J Thorac Cardiovasc Surg , vol.115 , pp. 168-176
    • Mack, C.A.1    Patel, S.R.2    Schwarz, E.A.3    Zanzonico, P.4    Hahn, R.T.5    Ilercil, A.6
  • 11
    • 0036147182 scopus 로고    scopus 로고
    • Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions
    • Crystal RG, Harvey BG, Wisnivesky JP, O'Donoghue KA, Chu KW, Maroni J, et al. Analysis of risk factors for local delivery of low- and intermediate-dose adenovirus gene transfer vectors to individuals with a spectrum of comorbid conditions. Hum Gene Ther 2002; 13: 65-100.
    • (2002) Hum Gene Ther , vol.13 , pp. 65-100
    • Crystal, R.G.1    Harvey, B.G.2    Wisnivesky, J.P.3    O'Donoghue, K.A.4    Chu, K.W.5    Maroni, J.6
  • 12
    • 0031809572 scopus 로고    scopus 로고
    • Therapeutic angiogenesis with basic fibroblast growth factor: Technique and early results
    • Sellke FW, Laham RJ, Edelman ER, Pearlman JD, Simons M. Therapeutic angiogenesis with basic fibroblast growth factor: Technique and early results. Ann Thorac Surg 1998; 65: 1540-1544.
    • (1998) Ann Thorac Surg , vol.65 , pp. 1540-1544
    • Sellke, F.W.1    Laham, R.J.2    Edelman, E.R.3    Pearlman, J.D.4    Simons, M.5
  • 13
    • 0033517733 scopus 로고    scopus 로고
    • Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: Results of a phase I randomized, double-blind, placebo-controlled trial
    • Laham RJ, Sellke FW, Edelman ER, Pearlman JD, Ware A, Brown DL. Local perivascular delivery of basic fibroblast growth factor in patients undergoing coronary bypass surgery: Results of a phase I randomized, double-blind, placebo-controlled trial. Circulation 1999; 100: 1865-1871.
    • (1999) Circulation , vol.100 , pp. 1865-1871
    • Laham, R.J.1    Sellke, F.W.2    Edelman, E.R.3    Pearlman, J.D.4    Ware, A.5    Brown, D.L.6
  • 14
    • 0037453099 scopus 로고    scopus 로고
    • VIVA Investigators. The VIVA trial: Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis
    • Henry TD, Annex BH, McKendall GR, Azrin MA, Lopez JJ, Giordano FJ, et al; VIVA Investigators. The VIVA trial: Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis. Circulation 2003; 107: 1359-1365.
    • (2003) Circulation , vol.107 , pp. 1359-1365
    • Henry, T.D.1    Annex, B.H.2    McKendall, G.R.3    Azrin, M.A.4    Lopez, J.J.5    Giordano, F.J.6
  • 15
  • 16
    • 33748155036 scopus 로고    scopus 로고
    • Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: A phase 2 randomized, controlled trial of AdVEGF(121) (AdVEGF121) versus maximum medical treatment
    • Stewart DJ, Hilton JD, Arnold JM, Gregoire J, Rivard A, Archer SL, et al. Angiogenic gene therapy in patients with nonrevascularizable ischemic heart disease: A phase 2 randomized, controlled trial of AdVEGF(121) (AdVEGF121) versus maximum medical treatment. Gene Ther 2006; 13: 1503-1511.
    • (2006) Gene Ther , vol.13 , pp. 1503-1511
    • Stewart, D.J.1    Hilton, J.D.2    Arnold, J.M.3    Gregoire, J.4    Rivard, A.5    Archer, S.L.6
  • 17
    • 0028827625 scopus 로고
    • II-365-II-371
    • Asahara T, Bauters C, Zheng LP, Takeshita S, Bunting S, Ferrara N, et al. title typecontributorSynergistic effect of vascular endothelial growth factor and basic fibroblast growth factor on angiogenesis in vivo/title. Circulation 1995; 92(Suppl): II-365-II-371.
    • (1995) Circulation , vol.92 , Issue.SUPPL.
    • Asahara, T.1    Bauters, C.2    Zheng, L.P.3    Takeshita, S.4    Bunting, S.5    Ferrara, N.6
  • 19
    • 0030756325 scopus 로고    scopus 로고
    • Pericyte loss and microaneurysm formation in PgDF-B-deficient mice
    • Lindahl P, Johansson BR, Levéen P, Betsholtz C. Pericyte loss and microaneurysm formation in PgDF-B-deficient mice. Science 1997; 277: 242-245.
    • (1997) Science , vol.277 , pp. 242-245
    • Lindahl, P.1    Johansson, B.R.2    Levéen, P.3    Betsholtz, C.4
  • 20
    • 1842416574 scopus 로고    scopus 로고
    • Oxygen(es) and the hypoxia-inducible factor-1
    • Wenger RH, Gassmann M. Oxygen(es) and the hypoxia-inducible factor-1. Biol Chem 1997; 378: 609-616.
    • (1997) Biol Chem , vol.378 , pp. 609-616
    • Wenger, R.H.1    Gassmann, M.2
  • 21
    • 26444585064 scopus 로고    scopus 로고
    • The efficacy of a 'master switch gene' HIF-1alpha in a porcine model of chronic myocardial ischaemia
    • Heinl-Green A, Radke PW, Munkonge FM, Frass O, Zhu J, Vincent K, et al. The efficacy of a 'master switch gene' HIF-1alpha in a porcine model of chronic myocardial ischaemia. Eur Heart J 2005; 26: 1327-1332.
    • (2005) Eur Heart J , vol.26 , pp. 1327-1332
    • Heinl-Green, A.1    Radke, P.W.2    Munkonge, F.M.3    Frass, O.4    Zhu, J.5    Vincent, K.6
  • 22
    • 33947727879 scopus 로고    scopus 로고
    • Use of a constitutively active hypoxia-inducible factor1alpha transgene as a therapeutic strategy in no-option critical limb ischemia patients: Phase I dose-escalation experience
    • Rajagopalan S, Olin J, Deitcher S, Pieczek A, Laird J, Grossman PM, et al. Use of a constitutively active hypoxia-inducible factor1alpha transgene as a therapeutic strategy in no-option critical limb ischemia patients: Phase I dose-escalation experience. Circulation 2007; 115: 1234-1243.
    • (2007) Circulation , vol.115 , pp. 1234-1243
    • Rajagopalan, S.1    Olin, J.2    Deitcher, S.3    Pieczek, A.4    Laird, J.5    Grossman, P.M.6
  • 23
    • 0024723470 scopus 로고
    • Recommendations for quantitation of the left ventricle by two-dimensional echocardiography: American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms
    • Schiller NB, Shah PM, Crawford M, DeMaria A, Devereux R, Feigenbaum H, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography: American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of Two-Dimensional Echocardiograms. J Am Soc Echocardiogr 1989; 2: 358-367.
    • (1989) J Am Soc Echocardiogr , vol.2 , pp. 358-367
    • Schiller, N.B.1    Shah, P.M.2    Crawford, M.3    Demaria, A.4    Devereux, R.5    Feigenbaum, H.6
  • 24
    • 0038481155 scopus 로고    scopus 로고
    • Adenoviral-mediated gene transfer of vascular endothelial growth factor in critical limb ischemia: Safety results from a phase I trial
    • Mohler ER 3rd, Rajagopalan S, Olin JW, Trachtenberg JD, Rasmussen H, Pak R, et al. Adenoviral-mediated gene transfer of vascular endothelial growth factor in critical limb ischemia: Safety results from a phase I trial. Vasc Med 2003; 8: 9-13.
    • (2003) Vasc Med , vol.8 , pp. 9-13
    • Mohler 3rd., E.R.1    Rajagopalan, S.2    Olin, J.W.3    Trachtenberg, J.D.4    Rasmussen, H.5    Pak, R.6
  • 25
    • 42549140599 scopus 로고    scopus 로고
    • TALISMAN 201 investigators. Therapeutic angiogenesis with intramuscular NV1FGF improves amputationfree survival in patients with critical limb ischemia
    • Nikol S, Baumgartner I, Van Belle E, Diehm C, Visoná A, Capogrossi MC, et al; TALISMAN 201 investigators. Therapeutic angiogenesis with intramuscular NV1FGF improves amputationfree survival in patients with critical limb ischemia. Mol Ther 2008; 16: 972.
    • (2008) Mol Ther , vol.16 , pp. 972
    • Nikol, S.1    Baumgartner, I.2    van Belle, E.3    Diehm, C.4    Visoná, A.5    Capogrossi, M.C.6
  • 26
    • 40949152736 scopus 로고    scopus 로고
    • Concomitant treatment with oral L-arginine improves the efficacy of surgical angiogenesis in patients with severe diffuse coronary artery disease: The Endothelial Modulation in Angiogenic Therapy randomized controlled trial
    • Ruel M, Beanlands RS, Lortie M, Chan V, Camac K N, de Kemp RA, et al. Concomitant treatment with oral L-arginine improves the efficacy of surgical angiogenesis in patients with severe diffuse coronary artery disease: The Endothelial Modulation in Angiogenic Therapy randomized controlled trial. J Thorac Cardiovasc Surg 2008; 135: 762-770.
    • (2008) J Thorac Cardiovasc Surg , vol.135 , pp. 762-770
    • Ruel, M.1    Beanlands, R.S.2    Lortie, M.3    Chan, V.4    Camac, K.N.5    de Kemp, R.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.