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Volumn 110, Issue 1, 2010, Pages 112-117

CDK5 phosphorylates eNOS at Ser-113 and regulates NO production

Author keywords

Alzheimer's diseases; Cdk5; eNOS; NO; Parkinson's diseases

Indexed keywords

CYCLIN DEPENDENT KINASE 5; ENDOTHELIAL NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRITE; PROTEIN P35; SERINE;

EID: 77951721375     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22515     Document Type: Article
Times cited : (10)

References (31)
  • 2
    • 0035425503 scopus 로고    scopus 로고
    • Nitric oxide synthases: Structure, function and inhibition
    • DOI 10.1042/0264-6021:3570593
    • Alderton WK, Cooper CE, Knowles RG. 2001. Nitric oxide synthases: Structure, function and inhibition. Biochem J 357:593-615. (Pubitemid 32735142)
    • (2001) Biochemical Journal , vol.357 , Issue.3 , pp. 593-615
    • Alderton, W.K.1    Cooper, C.E.2    Knowles, R.G.3
  • 6
    • 33846394480 scopus 로고    scopus 로고
    • Regional expression of NO synthase, NAD(P)H oxidase and superoxide dismutase in the rat brain
    • DOI 10.1016/j.brainres.2006.11.067, PII S0006899306034779
    • Campese VM, Sindhu RK, Ye S, Bai Y, Vaziri ND, Jabbari B. 2007. Regional expression of NO synthase, NAD(P)H oxidase and superoxide dismutase in the rat brain. Brain Res 1134:27-32. (Pubitemid 46135539)
    • (2007) Brain Research , vol.1134 , Issue.1 , pp. 27-32
    • Campese, V.M.1    Sindhu, R.K.2    Ye, S.3    Bai, Y.4    Vaziri, N.D.5    Jabbari, B.6
  • 8
    • 0028848093 scopus 로고
    • Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity
    • Chen PF, Tsai AL, Wu KK. 1995. Cysteine 99 of endothelial nitric oxide synthase (NOS-III) is critical for tetrahydrobiopterin-dependent NOS-III stability and activity. Biochem Biophys Res Commun 215:1119-1129.
    • (1995) Biochem Biophys Res Commun , vol.215 , pp. 1119-1129
    • Chen, P.F.1    Tsai, A.L.2    Wu, K.K.3
  • 10
    • 0034603525 scopus 로고    scopus 로고
    • Aberrant expression of nitric oxide synthase III in Alzheimer's disease: Relevance to cerebral vasculopathy and neurodegeneration
    • DOI 10.1016/S0197-4580(99)00108-6, PII S0197458099001086
    • de la Monte SM, Lu BX, Sohn YK, Etienne D, Kraft J, Ganju N, Wands JR. 2000. Aberrant expression of nitric oxide synthase III in Alzheimer's disease: Relevance to cerebral vasculopathy and neurodegeneration. Neurobiol Aging 21:309-319. (Pubitemid 30387090)
    • (2000) Neurobiology of Aging , vol.21 , Issue.2 , pp. 309-319
    • De La Monte, S.M.1    Lu, B.-X.2    Sohn, Y.-K.3    Etienne, D.4    Kraft, J.5    Ganju, N.6    Wands, J.R.7
  • 11
    • 45249095327 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase overexpression by neuronal cells in neurodegeneration: A link between inflammation and neuroprotection
    • DOI 10.1111/j.1471-4159.2008.05351.x
    • De Palma C, Falcone S, Panzeri C, Radice S, Bassi MT, Clementi E. 2008. Endothelial nitric oxide synthase overexpression by neuronal cells in neurodegeneration: A link between inflammation and neuroprotection. J Neurochem 106:193-204. (Pubitemid 351840202)
    • (2008) Journal of Neurochemistry , vol.106 , Issue.1 , pp. 193-204
    • De Palma, C.1    Falcone, S.2    Panzeri, C.3    Radice, S.4    Bassi, M.T.5    Clementi, E.6
  • 13
    • 33750928824 scopus 로고    scopus 로고
    • Protecting the brain with eNOS: Run for your life
    • Faraci FM. 2006. Protecting the brain with eNOS: Run for your life. Circ Res 99:1029-1030.
    • (2006) Circ Res , vol.99 , pp. 1029-1030
    • Faraci, F.M.1
  • 14
    • 0031893415 scopus 로고    scopus 로고
    • Regulation of the cerebral circulation: Role of endothelium and potassium channels
    • Faraci FM, Heistad DD. 1998. Regulation of the cerebral circulation: Role of endothelium and potassium channels. Physiol Rev 78:53-97. (Pubitemid 28070975)
    • (1998) Physiological Reviews , vol.78 , Issue.1 , pp. 53-97
    • Faraci, F.M.1    Heistad, D.D.2
  • 16
    • 0020448709 scopus 로고
    • 15N]nitrate in biological fluids
    • DOI 10.1016/0003-2697(82)90118-X
    • Green LC, Wagner DA, Glogowski J, Skipper PL, Wishnok JS, Tannenbaum SR. 1982. Analysis of nitrate, nitrite, and [15N]nitrate in biological fluids. Anal Biochem 126:131-138. (Pubitemid 13203451)
    • (1982) Analytical Biochemistry , vol.126 , Issue.1 , pp. 131-138
    • Green, L.C.1    Wagner, D.A.2    Glogowski, J.3
  • 17
    • 24144494527 scopus 로고    scopus 로고
    • The physiology and pathophysiology of nitric oxide in the brain
    • DOI 10.1016/j.pneurobio.2005.06.001, PII S030100820500064X
    • Guix FX, Uribesalgo I, Coma M, Munoz FJ. 2005. The physiology and pathophysiology of nitric oxide in the brain. Prog Neurobiol 76:126-152. (Pubitemid 41242885)
    • (2005) Progress in Neurobiology , vol.76 , Issue.2 , pp. 126-152
    • Guix, F.X.1    Uribesalgo, I.2    Coma, M.3    Munoz, F.J.4
  • 18
    • 64949131878 scopus 로고    scopus 로고
    • Hypothermia attenuates oxidative/nitrosative stress, encephalopathy and brain edema in acute (ischemic) liver failure
    • Jiang W, Desjardins P, Butterworth RF. 2009. Hypothermia attenuates oxidative/nitrosative stress, encephalopathy and brain edema in acute (ischemic) liver failure. Neurochem Int 55:124-128.
    • (2009) Neurochem Int , vol.55 , pp. 124-128
    • Jiang, W.1    Desjardins, P.2    Butterworth, R.F.3
  • 20
    • 22344439156 scopus 로고    scopus 로고
    • Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: Implications for mutant huntingtin toxicity
    • DOI 10.1083/jcb.200412071
    • Luo S, Vacher C, Davies JE, Rubinsztein DC. 2005. Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: Implications for mutant huntingtin toxicity. J Cell Biol 169:647-656. (Pubitemid 41002857)
    • (2005) Journal of Cell Biology , vol.169 , Issue.4 , pp. 647-656
    • Luo, S.1    Vacher, C.2    Davies, J.E.3    Rubinsztein, D.C.4
  • 21
    • 0034831233 scopus 로고    scopus 로고
    • The protein kinase cdk5: Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology
    • DOI 10.1046/j.1432-1327.2001.02024.x
    • Maccioni RB, Otth C, Concha II, Munoz JP. 2001. The protein kinase Cdk5. Structural aspects, roles in neurogenesis and involvement in Alzheimer's pathology. Eur J Biochem 268:1518-1527. (Pubitemid 32862683)
    • (2001) European Journal of Biochemistry , vol.268 , Issue.6 , pp. 1518-1527
    • Maccioni, R.B.1    Otth, C.2    Concha, I.I.3    Munoz, J.P.4
  • 24
    • 0037444453 scopus 로고    scopus 로고
    • Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1
    • Nguyen MD, Boudreau M, Kriz J, Couillard-Despres S, Kaplan DR, Julien JP. 2003. Cell cycle regulators in the neuronal death pathway of amyotrophic lateral sclerosis caused by mutant superoxide dismutase 1. J Neurosci 23: 2131-2140. (Pubitemid 36368901)
    • (2003) Journal of Neuroscience , vol.23 , Issue.6 , pp. 2131-2140
    • Nguyen, M.D.1    Boudreau, M.2    Kriz, J.3    Couillard-Despres, S.4    Kaplan, D.R.5    Julien, J.-P.6
  • 25
    • 67649861869 scopus 로고    scopus 로고
    • Combination treatment with normobaric hyperoxia and cilostazol protects mice against focal cerebral ischemia-induced neuronal damage better than each treatment alone
    • Nonaka Y, Koumura A, Hyakkoku K, Shimazawa M, Yoshimura S, Iwama T, Hara H. 2009. Combination treatment with normobaric hyperoxia and cilostazol protects mice against focal cerebral ischemia-induced neuronal damage better than each treatment alone. J Pharmacol Exp Ther 330:13-22.
    • (2009) J Pharmacol Exp Ther , vol.330 , pp. 13-22
    • Nonaka, Y.1    Koumura, A.2    Hyakkoku, K.3    Shimazawa, M.4    Yoshimura, S.5    Iwama, T.6    Hara, H.7
  • 26
    • 0037095763 scopus 로고    scopus 로고
    • Cyclin-Dependent Kinase 5/p35 Contributes Synergistically with Reelin/Dab1 to the Positioning of Facial Branchiomotor and Inferior Olive Neurons in the Developing Mouse Hindbrain
    • Ohshima T, Ogawa M, Takeuchi K, Takahashi S, Kulkarni AB, Mikoshiba K. 2002. Cyclin-dependent kinase 5/p35 contributes synergistically with Reelin/Dab1 to the positioning of facial branchiomotor and inferior olive neurons in the developing mouse hindbrain. J Neurosci 22: 4036-4044. (Pubitemid 37465712)
    • (2002) Journal of Neuroscience , vol.22 , Issue.10 , pp. 4036-4044
    • Ohshima, T.1    Ogawa, M.2    Takeuchi, K.3    Takahashi, S.4    Kulkarni, A.B.5    Mikoshiba, K.6
  • 29
    • 0033556652 scopus 로고    scopus 로고
    • Neuritic sprouting with aberrant expression of the nitric oxide synthase III gene in neurodegenerative diseases
    • DOI 10.1016/S0022-510X(98)00297-4, PII S0022510X98002974
    • Sohn YK, Ganju N, Bloch KD, Wands JR, de la Monte SM. 1999. Neuritic sprouting with aberrant expression of the nitric oxide synthase III gene in neurodegenerative diseases. J Neurol Sci 162:133-151. (Pubitemid 29125245)
    • (1999) Journal of the Neurological Sciences , vol.162 , Issue.2 , pp. 133-151
    • Sohn, Y.K.1    Ganju, N.2    Bloch, K.D.3    Wands, J.R.4    De La Monte, S.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.