Circulating phytosterols: biomarkers of the absorption of sterols in the normal diet and of adherence to vegetable sterol supplemented foods;Fitoesteroles circulantes: biomarcadores de la absorción de los esteroles de la dieta habitual y de adherencia a alimentos suplementados con esteroles vegetales

Actividad Dietetica

Volumn 14, Issue 1, 2010, Pages 3-9

  Escurriol, Verónica ^a,b   Cofán, Montserrat ^a,b   Ros, Emili ^a,b  

^a INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^b Instituto de Salud Carlos III   (Spain)

Author keywords

Cholesterol; Diet; Lathosterol; Phytosterols; Sitosterol

Indexed keywords

BIOLOGICAL MARKER; LATHOSTEROL; PHYTOSTEROL; PLACEBO; SITOSTEROL; VEGETABLE OIL;

ADULT; AGED; ARTICLE; CIRCULATION; CLINICAL TRIAL; CONCENTRATION (PARAMETERS); CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DIETARY INTAKE; FAT INTAKE; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; INTERVENTION STUDY; LIPID ABSORPTION; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MEDITERRANEAN DIET; MILK; MULTICENTER STUDY; OBSERVATIONAL STUDY; RANDOMIZED CONTROLLED TRIAL; VEGETABLE;

EID: 77951672444     PISSN: 11380322     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1138-0322(10)70002-X     Document Type: Article

References (28)

1. Moreau R.A., Whitaker B.D., and Hicks K.B. Phytosterols, phytostanols, and their conjugates in foods: structural diversity, quantitative analysis, and health-promoting uses. Prog Lipid Res 41 (2002) 457-500
2. Ros E. Intestinal absorption of triglyceride and cholesterol. Dietary and pharmacological inhibition to reduce cardiovascular risk. Atherosclerosis 151 (2000) 357-379
3. Ostlund Jr. R.E. Phytosterols in human nutrition. Annu Rev Nutr 22 (2002) 533-549
4. Plat J., and Mensink R.P. Plant stanol and sterol esters in the control of blood cholesterol levels: mechanism and safety aspects. Am J Cardiol 96 (2005) 15D-22D
5. Katan M.B., Grundy S.M., Jones P., Law M., Miettinen T., Paoletti R., and For the Stressa Workshop Participant. Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels. Mayo Clin Proc 78 (2003) 965-978
6. Demonty I., Ras R.T., Van der Knaap H.CM., Duchateau G.S.M.J.E., Meijer L., Zock P.L., et al. Continuous dose-response relationship of the LDL-cholesterol-lowering effect of phytosterol intake. J Nutr 139 (2009) 271-284
7. Ostlund Jr. R.E., Racette S.B., Okeke A., and Stenson W.F. Phytosterols that are naturally present in commercial corn oil significantly reduce cholesterol absorption in humans. Am J Clin Nutr 75 (2002) 1000-1004
8. Ostlund Jr. R.E., Racette S.B., and Stenson W.F. Inhibition of cholesterol absorption by phytosterol-replete wheat germ compared with phytosterol-depleted wheat germ. Am J Clin Nutr 77 (2003) 1385-1389
9. Andersson S.W., Skinner J., Ellegard L., Welch A.A., Bingham S., Mulligan A., et al. Intake of dietary plant sterols is inversely related to serum cholesterol concentration in men and women in the EPIC Norfolk population: a crosssectional study. Eur J Clin Nutr 58 (2004) 1378-1385
10. Klingberg S., Ellegard L., Johansson I., Hallmans G., Weinehall L., Andersson H., et al. Inverse relation between dietary intake of naturally occurring plant sterols and serum colesterol in northern Sweden. Am J Clin Nutr 87 (2008) 993-1001
11. Von Bergmann K., Sudhop T., and Lutjohann D. Cholesterol and plant sterol absorption: recent insights. Am J Cardiol 96 Suppl (2005) 10D-4
12. Berge K.E., Tian H., Graf G.A., Yu L., Grishin N.V., Schultz J., et al. Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters. Science 290 (2000) 1771-1775
13. Patel M.D., and Thompson P.D. Phytosterols and vascular disease. Atherosclerosis 186 (2006) 12-19
14. Chan Y.M., Varady K.A., Lin Y., Trautwein E., Mensink R.P., Plat J., et al. Plasma concentrations of plant sterols: physiology and relationship with coronary heart disease. Nutr Rev 64 (2006) 385-402
15. Miettinen T.A., Tilvis R.S., and Kesaniemi Y.A. Serum plant sterols and cholesterol precursors reflect cholesterol absorption and synthesis in volunteers of a randomly selected male population. Am J Epidemiol 131 (1990) 20-31
16. Gylling H., and Miettinen T.A. Cholesterol absorption: influence of body weight and the role of plant sterols. Curr Atheroscler Rep 7 (2005) 466-471
17. Santosa S., Varady K.A., AbuMweis S., and Jones P.J. Physiological and therapeutic factors affecting cholesterol metabolism: does a reciprocal relationship between cholesterol absorption and synthesis really exist?. Life Sci 80 (2007) 505-514
18. Estruch R., Martinez-Gonzalez M.A., Corella D., Salas-Salvado J., Ruiz-Gutierrez V., Covas M.I., et al., For the PREDIMED study investigators. Effects of a Mediterraneanstyle diet on cardiovascular risk factors: a randomized trial. Ann Intern Med 145 (2006) 1-11
19. Escurriol V., Cofán M., Serra M., Bulló M., Basora J., Salas-Salvadó J., et al. Serum sterol responses to increasing plant sterol intake from natural foods in the Mediterranean diet. Eur J Nutr 48 (2009) 373-382
20. Gonzalez C.A., Navarro C., Martinez C., Quiros J.R., Dorronsoro M., Barricarte A., et al. Grupo EPIC de España. El estudio prospectivo europeo sobre dieta, cáncer y salud (EPIC) en España. Med Clin (Barc) 102 (1994) 781-785
21. Escurriol V., Cofan M., Moreno-Iribas C., Larranaga N., Martinez C., Navarro C., et al. Phytosterol plasma concentrations and coronary heart disease in the prospective Spanish EPIC cohort. J Lipid Res. (2009) [Epub ahead of print].
22. Jimenez-Escrig A., Santos-Hidalgo A.B., and Saura-Calixto F. Common sources and estimated intake of plant sterols in the Spanish diet. J Agric Food Chem 54 (2006) 3462-3471
23. Martin-Moreno J.M., Boyle P., Gorgojo L., Maisonneuve P., Fernandez-Rodriguez J.C., Salvini S., et al. Development and validation of a food frequency questionnaire in Spain. Int J Epidemiol 22 (1993) 512-519
24. EPIC Group of Spain. Relative validity and reproducibility of a diet history questionnaire in Spain. I. Foods. Int J Epidemiol 26 Suppl 1 (1997) S91-S99
25. EPIC Group of Spain. Relative validity and reproducibility of a diet history questionnaire in Spain. II. Nutrients. Int J Epidemiol 26 Suppl 1 (1997) S100-S109
26. Friedewald W.T., Levy R.I., and Fredrickson D.S. Estimation of the concentration of lowdensity lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18 (1972) 499-502
27. Heinemann T., Axtmann G., and Von Bergmann K. Comparison of intestinal absorption of cholesterol with different plant sterols in man. Eur J Clin Invest 23 (1993) 827-831
28. Sarkkinen E.S., Uusitupa M.I., Gylling H., and Miettinen T.A. Fat-modified diets influence serum concentrations of cholesterol precursors and plant sterols in hypercholesterolemic subjects. Metabolism 47 (1998) 744-750