The influence of heterogeneous nucleation on the surface crystallization of guaifenesin from melt extrudates containing Eudragit® L10055 or Acryl-EZE®

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 75, Issue 1, 2010, Pages 71-78

  Bruce, Caroline D ^a   Fegely, Kurt A ^a   Rajabi Siahboomi, Ali R ^a   McGinity, James W ^a  

^a The University of Texas at Austin ^*  (United States)

Author keywords

Acryl EZE ; Eudragit L10055; Guaifenesin; Hot melt extrusion; Matrix tablets; Physical stability; Recrystallization; Relative humidity; Storage; Talc

Indexed keywords

ACRYL EZE; EUDAGRIT; EUDRAGIT; GUAIFENESIN; TALC; UNCLASSIFIED DRUG;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYSTALLIZATION; DRUG SOLUBILITY; DRUG STORAGE; HUMIDITY; QUANTITATIVE ASSAY; STORAGE TEMPERATURE; SURFACE PROPERTY; WATER TRANSPORT;

ACRYLAMIDES; ACRYLIC RESINS; CRYSTALLIZATION; EXCIPIENTS; GUAIFENESIN; HOT TEMPERATURE; POLYVINYLS; SURFACE PROPERTIES;

EID: 77951652381     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2009.12.001     Document Type: Article

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