Antihyperlipidemic activity of Helicteres isora fruit extract on streptozotocin induced diabetic male wistar rats

European Review for Medical and Pharmacological Sciences

Volumn 14, Issue 3, 2010, Pages 191-196

  Boopathy Raja, A ^a   Elanchezhiyan, C ^a   Sethupathy, S ^a  

^a ANNAMALAI UNIVERSITY   (India)

Author keywords

Antihyperlipidemic activity; Diabetes mellitus; Helicteres isora; Streptozotocin

Indexed keywords

CHOLESTEROL; GLIBENCLAMIDE; HELICTERES ISORA FRUIT EXTRACT; HERBACEOUS AGENT; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PHOSPHOLIPID; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN; ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; LIPID; PLANT EXTRACT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; FRUIT; HELICTERES ISORA; HYPERLIPIDEMIA; LIPID BLOOD LEVEL; LIPID LIVER LEVEL; MALE; NONHUMAN; RAT; STREPTOZOCIN DIABETES; ANIMAL; BLOOD; COMPARATIVE STUDY; EXPERIMENTAL DIABETES MELLITUS; LIVER; METABOLISM; STERCULIACEAE; TIME; WISTAR RAT;

ANIMALS; ANTILIPEMIC AGENTS; DIABETES MELLITUS, EXPERIMENTAL; FRUIT; GLYBURIDE; HYPERLIPIDEMIAS; HYPOGLYCEMIC AGENTS; LIPIDS; LIVER; MALE; PLANT EXTRACTS; RATS; RATS, WISTAR; STERCULIACEAE; TIME FACTORS;

EID: 77951650073     PISSN: 11283602     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (40)

1. WHO STUDY GROUP REPORT. Diabetes mellitus. WHO Tech Rep Ser 1985; 727: 1-113.
2. RAMESH B, VISWANATHAN P, PUGALENDI KV. Protective effect of Umbelliferone on membranous fatty acid composition in streptozotocin-induced diabetic rats. Eur J Pharmacol 2007; 566: 231-239. (Pubitemid 46782809)
3. NAGAPPA AN, THAKURDESAI PA, VENKAT RAO N, JIWAN SINGH. Antidiabetic activity of Terminalia catappa Linn fruits. J Ethnopharmacol 2003; 88: 45-50.
4. SHASTRI K. Comments on Charaka Samhita. Varanasi: Chanukah Bharati, 1980.
5. LI WL, ZHENG HC, BUKURU J, DE KIMPE N. Natural medicines used in the traditional Chinese medical system for therapy of diabetes mellitus. J Ethnopharmacol 2004; 92: 1-21.
6. KAMESWARA RAO B, KESAVULU MM, GIRI R, APPA RAO CH. Antidiabetic and hypolipidemic effects of Momordica cymbalaria Hook, fruit powder in alloxan diabetic rats. J Ethnopharmacol 1999; 67: 103-109.
7. BHATTARAM VA, CERAEFE M, KOHLEST C, VEST M, DEUNDORF H. Pharmacokinetics and bioavailability of herbal medicinal products. Phytomed 2002; 9: 1-36.
8. NEVEEN HELMY ABOU EL-SOUD MY, KHALIL JS, HUSSEIN FS, ORABY H, HUSSEIN FARRAG AR. Antidiabetic effects of fenugreek alkaloid extract in streptozotocin induced hyperglycemic rats. J Applied Sci Res 2007; 3: 1073-1083.
9. LOEW D, KASZKIN M. Approaching the problem of bioequivalence of herbal medicinal products. Phytother Res 2002; 16: 705-711.
10. WORLD HEALTH ORGANISATION. The WHO Expert Committee on Diabetes Mellitus. Technical Report Series 646: Geneva and World Health Organization, 1980.
11. MITRA SK, GOPUMADHAVAN S, MURALIDHAR TS, ANTURLIKAR SD, SUJATHA MB. Effect of a herbomineral preparation D-400 in streptozotocin induced diabetic rats. J Ethnopharmacol 1996; 54: 41-46.
12. HALBERSTEIN RA. Medicinal plants: historical and cross-cultural usage patterns. Ann Epidemiol 2005; 15: 686-899.
13. CHAKRABARTI R, REEBA K, VIKRAMADITHYAN, RAMESH MULLANGI, SHARMA VM, JAGADHESHAN H, RAO YN, SAIRAM P, RAJAGOPALAN R. Antidiabetic and hypolipidemic activity of Helicteres isora in animal models. J Ethnopharmacol 2002; 81: 343-349.
14. KUMAR G, MURUGESAN AG, RAJASEKAR PANDIAN M. Hypolipidaemic activity of Helicteres isora L. bark extracts in streptozotocin induced diabetic rats. J Ethnopharmacol 2008; 116: 161-166.
15. SATAKE T, KAMIYA K, SAIKI Y, HAMA T, FUJIMOTO Y, KITANAKA S, KIMURA Y, UZAWA J, ENDANG H, UMAR M. Studies on the constituents of fruits of Helicteres isora L. Chem Pharm Bull 1999; 47: 1444-1447.
16. BOOPATHY RAJA A, ELANCHEZHIYAN C, MANOHARAN S, SURESH K, BALAKRISHNAN S, SETHUPATHY S. Evaluation of antihyperglycemic potential of Helicteres isora in streptozotocin induced diabetic wistar rats. J Cell Tissue Res 2009; 9: 1925-1928.
17. HOSSAIN MZ, SHIBIB BA, RAHMAN R. Hypoglycemic effects of Coccirda indica: inhibition of key gluconeogenic enzyme, glucose-6- phosphatase. Indian J Experimental Biol 1992; 10: 418-420.
18. SASAKI T, MATSY S, SONAE A. Effect of acetic acid concentration on the colour reaction in the O-toluidine boric acid method for blood glucose estimation. Rinsho Kagaku 1972; 1: 346-353.
19. PAREKH AC, JUNG DH. Cholesterol determination with ferric acetate uranyl acetate and sulphuric acid-ferrous sulphate reagents. Analytical Chemistry 1970; 42: 1423-1427.
20. ZILVERSMIT DB, DAVIS AK, MEMPHIS B, TENN N. Estimation of phospholipids in biological fluids. J Lab Clin Med 1950; 35: 155-160.
21. FOSTER CS, DUNN O. Stable reagents for determination of serum triglycerides by a colorimetric hantzsch condensation method. Clin Chem 1973; 19: 338-340.
22. GIDEZ WM, WEBB M. Revision of cholesterol determination. J Biochem 1950; 187: 97-106.
23. FRIEDEWALD WT, LEVY RI, FREDERICKSON DS. Estimation of the concentration of low density lipoprotein cholesterol in plasma, without use of preparative ultracentrifuge. Clin Chem 1972; 18: 499-502.
24. ABBOTT RD, WILSON PW, KANNEL WB, CASTELLI WP. High density lipoprotein-cholesterol, total cholesterol screening and myocardial infarction. The Framingham Study. Arterosclerosis 1988; 8: 207-211.
25. ALLADI S, SHANMUGASUNDARAM KR. Induction of hypercholesterolemia by supplementing soy protein with acetate generating amino-acids. Nutr Rep Int 1989; 40: 893-899.
26. SATYANARAYANA U, CHAKRAPANI U. Biochemistry. 3rd ed. Kolkatta (India): Books and Allied (P) Ltd; 2007.
27. MANIMEGALAI A, GEETHA H, RAJALAKSHMI K. Effect of vitamin E on high fat diet induced hyperlipidemia in rats. Indian J Exp Biol 1993; 31: 704-707. (Pubitemid 23302387)
28. MURALI B, UPADHYAYA UM, GOYAL RK. Effect of chronic treatment with Enicostemma littorale in non-insulin dependent diabetic (NIDDM) rats. J Ethnopharmacol 2002; 81: 199-204.
29. SHIRWAIKAR A, RAJENDRAN K, KUMAR CD, BODLA R. Antidiabetic activity of aqueous leaf extract of Annona squamosa in streptozotocin-nicotinamide type 2 diabetic rats. J Ethnopharmacol 2004; 91: 171-175.
30. PUSHPARAJ PN, LOW HK, MANIKANDAN J, TAN BK, TAN CH. Anti-diabetic effects of Cichorium intybus in streptozotocin-induced diabetic rats. J Ethnopharmacol 2007; 111: 430-434.
31. SHARMA SB, NASIR A, PRABHU KM, MURTHY PS, DEV G. Hypoglycaemic and hypolipidemic effect of ethanolic extract of seeds of Eugenia jambolana in alloxan-induced diabetic rabbits. J Ethnopharmacol 2003; 85: 201-206.
32. AL-SHAMAONY L, AL-KHAZNAJI SM, TWAY HAA. Hypoglycaemic effect of Artemisia herba alba II. Effect of valuable extract on some blood parameters, in diabetic animals. J Ethnopharmacol 1994; 43: 167-171.
33. JAIN SK, MCVIE R, MEACHUAN ZD, SMITH T. Effect of LDL and VLDL oxidizability and hyperglycemia on blood cholesterol, phospholipid and triglyceride levels in type I diabetic patients. Atherosclerosis 2000; 149: 69-73.
34. BOPANNA KN, KANNAN J, SUSMA G, BALARAMAN R, RATHOD SP. Antidiabetic and Antihyperlipidemic effect of neem seed kernel powder on alloxan induced diabetic rats. Indian J Pharmacol 1997; 29: 162-167.
35. BALAMURUGAN K, INDRA N, VANITHAKUMARI G. Effect of rifampicin on certain lipid profiles in the liver of albino rats. Indian J Environ Ecoplan 2009; 16: 25-28.
36. LEMHADRI A, HAJJI L, MICHEL JB, EDDOUKS M. Cholesterol and triglycerides lowering activities of car-away fruits in normal and streptozotocin diabetic rats. J Ethnopharmacol 2006; 106: 321-326. (Pubitemid 43914300)
37. MAYNE PD. Clinical chemistry in diagnosis and treatment. Edward Arnold (A division of Hodder Headline Plc), London, pp. 224-241: 1996.
38. SINGH SK, KESARI AN, GUPTA RK, JAISWAL D, WATAL G. Assessment of antidiabetic potential of Cynodon dactylon extract in streptozotocin diabetic rats. J Ethnopharmacol 2007; 114: 174-179.
39. TEMME EH, VAN HPG, SCHOUTEN EG, KESTELOOT H. Effect of a plant sterol-enriched spread on serum lipids and lipoprotein in mildly hypercholesterolaemic subjects. Acta Cardiol 2002; 57: 111-115.
40. DAVIDSON MB. Diabetes mellitus diagnosis and treatment. Wiley, New York, pp. 27, 48, 109, 157: 1981.