Alpha-lipoic acid regulates heme oxygenase gene expression and nuclear Nrf2 activation as a mechanism of protection against arsenic exposure in HepG2 cells

Environmental Toxicology and Pharmacology

Volumn 29, Issue 2, 2010, Pages 144-149

  Huerta Olvera, Selene G ^a,c   Macías Barragán, José ^d   Ramos Márquez, Martha E ^d   Armendáriz Borunda, Juan ^c,d   Díaz Barriga, Fernando ^b   Siller López, Fernando ^d  

^a UNIVERSIDAD AUTÓNOMA DE SAN LUIS POTOSÍ   (Mexico)

^b UNIVERSIDAD AUTÓNOMA DE SAN LUIS POTOSÍ   (Mexico)

^c HOSPITAL CIVIL DE GUADALAJARA FRAY ANTONIO ALCALDE   (Mexico)

^d UNIVERSITY OF GUADALAJARA   (Mexico)

Author keywords

Alpha lipoic acid; Antioxidant gene expression; Arsenic; Heme oxygenase; HepG2; Nrf2

Indexed keywords

ARSENIC; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE; METALLOTHIONEIN; THIOCTIC ACID; TRANSCRIPTION FACTOR NRF2;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL PROTECTION; CELL STRAIN HEPG2; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; ENZYME ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

EID: 77951622584     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2009.12.004     Document Type: Article

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