HO-1 expression in type II pneumocytes after transpulmonary gene delivery

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 278, Issue 6 22-6, 2000, Pages

  Weng, Yi Hao ^a   Tatarov, Arthur ^a   Bartos, Blythe P ^a   Contag, Christopher H ^a   Dennery, Phyllis A ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bioluminescence; Doxycycline; Heme oxygenase 1; Oxidative stress

Indexed keywords

HEME OXYGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOLUMINESCENCE; ENZYME ACTIVITY; GENE EXPRESSION; GENE TARGETING; IMMUNOCYTOCHEMISTRY; LUMINESCENCE; LUNG ALVEOLUS CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL;

EID: 0033921474     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.2000.278.6.l1273     Document Type: Article

References (30)

1. Abraham NG, Lavrovsky Y, Schwartzman ML, Stoltz RA, Levere RD, Gerritsen ME, Shibahara S, and Kappas A. Transfection of the human heme oxygenase gene into rabbit coronary microvessel endothelial cells: protective effect against heme and hemoglobin toxicity. Proc Natl Acad Sci USA 92: 6798-6802, 1995.
2. Adamson IY and Bowden DH. The type 2 cell as progenitor of alveolar epithelial regeneration. A cytodynamic study in mice after exposure to oxygen. Lab Invest 30: 35-42, 1974.
3. Baron U, Freundlieb S, Gossen M, and Bujard H. Co-regulation of two gene activities by tetracycline via a bidirectional promoter. Nucleic Acids Res 23: 3605-3606, 1995.
4. Bruening W, Giasson B, Mushynski W, and Durham HD. Activation of stress-activated MAP protein kinases up-regulates expression of transgenes driven by the cytomegalovirus immediate/early promoter. Nucleic Acids Res 26: 486-489, 1998.
5. Contag CH, Spilman SD, Contag PR, Oshiro M, Eames B, Dennery P, Stevenson DK, and Benaron DA. Visualizing gene expression in living mammals using a bioluminescent reporter. Photochem Photobiol 66: 523-531, 1997.
6. Curiel DT, Pilewski JM, and Albelda SM. Gene therapy approaches for inherited and acquired lung diseases. Am J Respir Cell Mol Biol 14: 1-18, 1996.
7. Danel C, Erzurum SC, Prayssac P, Eissa NT, Crystal RG, Herve P, Baudet B, Mazmanian M, and Lemarchand P. Gene therapy for oxidant injury-related diseases: adenovirus-mediated transfer of superoxide dismutase and catalase cDNAs protects against hyperoxia but not against ischemia-reperfusion lung injury. Hum Gene Ther 9: 1487-1496, 1998.
8. Dennery PA, Rodgers PA, Lum MA, Jennings BC, and Shokoohi V. Hyperoxic regulation of lung heme oxygenase in neonatal rats. Pediatr Res 40: 815-821, 1996.
9. Dennery PA, Spitz DR, Yang G, Tatarov A, Lee CS, Shegog ML, and Poss KD. Oxygen toxicity and iron accumulation in the lungs of mice lacking heme oxygenase-2. J Clin Invest 101: 1001-1011, 1998.
10. Dennery PA, Sridhar KJ, Lee CS, Wong HE, Shokoohi V, Rodgers PA, and Spitz DR. Heme oxygenase-mediated resistance to oxygen toxicity in hamster fibroblasts. J Biol Chem 272: 14937-14942, 1997.
11. Freeman BA, Panus PC, Matalon S, Buckley BJ, and Baker RR. Oxidant injury to the alveolar epithelium: biochemical and pharmacologic studies. Res Rep Health Eff Inst 54: 1-30, 1993.
12. Fujita M, Kuwano K, Kunitake R, Hagimoto N, Miyazaki H, Kaneko Y, Kawasaki M, Maeyama T, and Hara N. Endothelial cell apoptosis in lipopolysaccharide-induced lung injury in mice. Int Arch Allergy Immunol 117: 202-208, 1998.
13. Lee PJ, Alam J, Sylvester SL, Inamdar N, Otterbein L, and Choi AM. Regulation of heme oxygenase-1 expression in vivo and in vitro in hyperoxic lung injury. Am J Respir Cell Mol Biol 14: 556-568, 1996.
14. Lee PJ, Alam J, Wiegand GW, and Choi AM. Overexpression of heme oxygenase-1 in human pulmonary epithelial cells results in cell growth arrest and increased resistance to hyperoxia. Proc Natl Acad Sci USA 93: 10393-10398, 1996.
15. Li S and Huang L. In vivo gene transfer via intravenous administration of cationic lipid-protamine-DNA (LPD) complexes. Gene Ther 4: 891-900, 1997.
16. Li Y, Zhang W, Mantell LL, Kazzaz JA, Fein AM, and Horowitz S. Nuclear factor-kappaB is activated by hyperoxia but does not protect from cell death. J Biol Chem 272: 20646-20649, 1997.
17. Liu TZ, Stern A, and Morrow JD. The isoprostanes: unique bioactive products of lipid peroxidation. An overview. J Biomed Sci 5: 415-420, 1998.
18. Otterbein LE, Kolls JK, Mantell LL, Cook JL, Alam J, and Choi AM. Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. J Clin Invest 103: 1047-1054, 1999.
19. Putman E, van Golde LM, and Haagsman HP. Toxic oxidant species and their impact on the pulmonary surfactant system. Lung 175: 75-103, 1997.
20. Sambucetti LC, Cherrington JM, Wilkinson GW, and Mocarski ES. NF-kappa B activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation. EMBO J 8: 4251-4258, 1989.
21. Sheard MA, Vbjtesek B, Janakova L, Kovarik J, and Zaloudik J. Up-regulation of Fas (CD95) in human p53 wild-type cancer cells treated with ionizing radiation. Int J Cancer 73: 757-762, 1997.
22. Stadtman ER and Berlett BS. Reactive oxygen-mediated protein oxidation in aging and disease. Chem Res Toxicol 10: 485-494, 1997.
23. Suttner DM and Dennery PA. Reversal of HO-1 related cytoprotection with increased expression is due to reactive iron. FASEB J 13: 1800-1809, 1999.
24. Suttner DM, Sridhar K, Lee CS, Tomura T, Hansen TN, and Dennery PA. Protective effects of transient HO-1 overexpression on susceptibility to oxygen toxicity in lung cells. Am J Physiol Lung Cell Mol Physiol 276: L443-L451, 1999.
25. Taylor JL, Carraway MS, and Piantadosi CA. Lung-specific induction of heme oxygenase-1 and hyperoxic lung injury. Am J Physiol Lung Cell Mol Physiol 274: L582-L590, 1998.
26. Tom DJ, Rogers LK, McNaughton KM, Geske RS, DeMayo FJ, Welty SE, and Smith CV. Mice expressing a heme oxygenase-1 (HO-1) trangene driven by a surfactant protein C (SPC) promoter are more susceptible to hyperoxic lung injury (Abstract). Pediatr Res 45: 71A, 1999.
27. Vreman HJ and Stevenson DK. Heme oxygenase activity as measured by carbon monoxide production. Anal Biochem 168: 31-38, 1988.
28. Wilks A and Ortiz de Montellano PR. Rat liver heme oxygenase. High level expression of a truncated soluble form and nature of the meso-hydroxylating species. J Biol Chem 268: 22357-22362, 1993.
29. Witschi H. Role of the epithelium in lung repair. Chest 99: 22S-25S, 1991.
30. Zager RA, Burkhart KM, Conrad DS, and Gmur DJ. Iron heme oxygenase, and glutathione: effects on myohemoglobinuric proximal tubular injury. Kidney Int 48: 1624-1634, 1995.