Expression of the reverse tetracycline-transactivator gene causes emphysema-like changes in mice

American Journal of Respiratory Cell and Molecular Biology

Volumn 34, Issue 5, 2006, Pages 552-560

  Sisson, Thomas H ^a   Hansen, Jean M ^b   Shah, Mitali ^b   Hanson, Kerstin E ^b   Du, Ming ^b   Ling, Tony ^b   Simon, Richard H ^b   Christensen, Paul J ^b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b NONE

Author keywords

Alveolar enlargement; Human surfactant protein C promoter; Rat Clara cell secretory protein promoter; Reverse tetracycline transactivator; Urokinase

Indexed keywords

DOXYCYCLINE; GAMMA INTERFERON; INTERLEUKIN 11; INTERLEUKIN 13; INTERLEUKIN 1BETA; REVERSE TETRACYCLINE TRANSACTIVATOR PROTEIN; SURFACTANT PROTEIN C; TRANSACTIVATOR PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; UROKINASE;

ACCURACY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLARA CELL; CONTROLLED STUDY; EMPHYSEMA; GENE; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENOTYPE; LUNG ALVEOLUS EPITHELIUM; LUNG ALVEOLUS WALL; LUNG COMPLIANCE; MOUSE; NONHUMAN; PATHOGENESIS; PHENOTYPE; PROMOTER REGION; REVERSE TETRACYCLINE TRANSACTIVATOR GENE; TETRACYCLINE OPERATOR GENE; TISSUE SPECIFICITY; TOTAL LUNG CAPACITY; TRANSGENIC MOUSE;

ANIMALS; BODY WEIGHT; DOXYCYCLINE; EMPHYSEMA; GENE EXPRESSION; GENOTYPE; KINETICS; LUNG COMPLIANCE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PROMOTER REGIONS (GENETICS); PULMONARY ALVEOLI; PULMONARY SURFACTANT-ASSOCIATED PROTEIN C; TETRACYCLINE; TOTAL LUNG CAPACITY; TRANS-ACTIVATORS; URINARY PLASMINOGEN ACTIVATOR; UTEROGLOBIN;

ANIMALIA; MURINAE; MUS MUSCULUS;

EID: 33646460899     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2005-0378OC     Document Type: Article

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