Effects of estrogen deficiency and low bone mineral density on healthy knee cartilage in rabbits

Journal of Orthopaedic Research

Volumn 28, Issue 6, 2010, Pages 812-818

  Castañeda, Santos ^a,b   Largo, Raquel ^a   Calvo, Emilio ^a   Bellido, Miriam ^a   Gómez Vaquero, Carmen ^c   Herrero Beaumont, Gabriel ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

^c HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

Author keywords

Animal models; Cartilage; Estrogens; Osteoporosis; Ovariectomy

Indexed keywords

GLUCOCORTICOID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE DENSITY; CARTILAGE; CONTROLLED STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; ESTROGEN DEFICIENCY; FEMALE; HISTOPATHOLOGY; KNEE; NONHUMAN; OSTEOPOROSIS; PRIORITY JOURNAL; RABBIT;

ABSORPTIOMETRY, PHOTON; ANIMALS; BONE DENSITY; CARTILAGE, ARTICULAR; ESTROGENS; FEMALE; KNEE JOINT; MAGNETIC RESONANCE IMAGING; OVARIECTOMY; RABBITS;

EID: 77951471164     PISSN: 07360266     EISSN: 1554527X     Source Type: Journal    
DOI: 10.1002/jor.21054     Document Type: Article

References (43)

1. Robin Poole A, Guilak F, Abramson SB. 2007. Etiopathogenesis of osteoarthritis. In: Moskowitz RW, Altman RD, Hochberg MC, et al. editors. Osteoarthritis, 4th ed. Philadelphia: Lippincott; p 27-49.
2. Herrero-Beaumont G, Roman-Blas JA, Castañ eda S, et al. 2009. Primary osteoarthritis no longer primary: three subsets with distinct etiological, clinical, and therapeutic characteristics. Semin Arthritis Rheum 39:71-80.
3. Felson DT, Lawrence RC, Dieppe PA, et al. 2000. Osteoarthritis: new insights. Part 1: the disease and its risk factors. Ann Intern Med 133:635-646.
4. Wluka AE, Cicuttini FM, Spector TD. 2000. Menopause, oestrogens and arthritis. Maturitas 35:183-199.
5. Gokhale JA, Frenkel SR, DiCesare PE. 2004. Estrogen and osteoarthritis. Am J Orthop 33:71-80.
6. Sniekers YH, Weinans H, Bierma-Zeinstra SM, et al. 2008. Animal models for osteoarthritis: the effect of ovariectomy and estrogen treatment - a systematic approach. Osteoarthritis Cartilage 16:533-541.
7. Roman-Blas JA, Castañ eda S, Largo R, et al. 2009. Osteoarthritis associated with estrogen deficiency. Arthritis Res Ther 11:241.
8. Hart DJ, Mootoosamy I, Doyle DV, et al. 1994. The relationship between osteoarthritis and osteoporosis in general population: the Chingford Study. Ann Rheum Dis 53:158-162. (Pubitemid 24123867)
9. Sambrook P, Naganathan V. 1997. What is the relationship between osteoarthritis and osteoporosis? Baillieres Clin Rheumatol 11:695-710.
10. Dequeker J, Aerssens J, Luyten FP. 2003. Osteoarthritis and osteoporosis: clinical and research evidence of inverse relationship. Aging Clin Exp Res 15:426-439. (Pubitemid 37509168)
11. Ng MC, Revell PA, Beer M, et al. 1984. Incidence of metabolic bone disease in rheumatoid arthritis and osteoarthritis. Ann Rheum Dis 43:370-377. (Pubitemid 14117904)
12. Hochberg MC, Lethbridge-Cejku M, Scott WW, et al. 1995. Upper extremity bone mass and osteoarthritis of the knees: data from the Baltimore Longitudinal Study of Aging. J Bone Miner Res 10:432-438. (Pubitemid 24261542)
13. Calvo E, Castañ eda S, Largo R, et al. 2007. Osteoporosis increases the severity of cartilage damage in an experimental model of osteoarthritis in rabbits. Osteoarthritis Cartilage 15:69-77.
14. Brandt KD. 2002. Animal models of osteoarthritis. Biorheology 39:221-235.
15. Turner AS. 2001. Animal models of osteoporosis - necessity and limitations. Eur Cell Mater 1:66-81.
16. Castañ eda S, Calvo E, Largo R, et al. 2008. Characterization of a new experimental model of osteoporosis in rabbits. J Bone Miner Metab 26:53-59.
17. Mori H, Manabe M, Kurachi Y, et al. 1997. Osteointegration of dental implants in rabbit bone with low mineral density. J Oral Maxillofac Surg 55:351-361. (Pubitemid 27167268)
18. Castañ eda S, Largo R, Calvo E, et al. 2006. Bone mineral measurements of subchondral and trabecular bone in healthy and osteoporotic rabbits. Skeletal Radiol 35:34-41.
19. Calvo E, Palacios I, Delgado E, et al. 2001. High resolution MRI detects cartilage swelling at early stages of experimental osteoarthritis. Osteoarthritis Cartilage 9:463-472. (Pubitemid 32734349)
20. Calvo E, Palacios I, Delgado E, et al. 2004. Cartilage swelling detected by MRI in early experimental OA represents proteoglycan depletion. Osteoarthritis Cartilage 12:878-886.
21. Mankin HJ, Dorfman H, Lippiello L, et al. 1971. Biochemical and metabolic abnormalities in articular cartilage from osteoarthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J Bone Joint Surg [Am] 53: 523-537.
22. Pelletier JP, Martel Pelletier J, Cloutier JM, et al. 1987. Proteoglycan-degrading acid metalloprotease activity in human osteoarthritic cartilage, and the effect of intraarticular steroid injections. Arthritis Rheum 30:541-548.
23. Ehrlich MG, Armstrong AL, Treadwell BV, et al. 1986. Degradative enzyme systems in cartilage. Clin Orthop 213: 62-68.
24. Delise AM, Fisher L, Tuan R. 2000. Cellular interactions and signaling in cartilage development. Osteoarthritis Cartilage 8:309-334.
25. Pacifici M, Koyama E, Iwamoto M, et al. 2000. Development of articular cartilage: what do we know about it and how may it occur? Connect Tissue Res 41:175-184.
26. Hoegh-Andersen P, Tankó LB, Andersen TL, et al. 2004. Ovariectomized rats as a model postmenopausal osteoarthritis: validation and application. Arthritis Res Ther 6:R169-R180.
27. Cake MA, Appleyard RC, Read RA, et al. 2005. Ovariectomy alters the structural and biomechanical properties of ovine femoro-tibial articular cartilage and increases cartilage iNOS. Osteoarthritis Cartilage 13:1066-1075.
28. Richette P, Dumontier MF, François M, et al. 2004. Dual effects of 17beta-oestradiol on IL 1beta-induced proteoglycan degradation in chondrocytes. Ann Rheum Dis 63:191-199. (Pubitemid 38122140)
29. Richette P, Dumontier MF, Tahiri K, et al. 2007. Oestrogens inhibit interleukin 1beta-mediated nitric oxide synthase expression in articular chondrocytes through nuclear factor-kappa B impairment. Ann Rheum Dis 66:345-350. (Pubitemid 46579636)
30. Silberberg M, Silberberg R. 1969. Effect of castration and intermittent administration of estrogen on knee joints and femoral shafts of mice. Pathol Microbiol (Basel) 33:274-286.
31. Ham KD, Loeser RF, Lindgren BR, et al. 2002. Effects of longterm estrogen replacement therapy on osteoarthritis severity in cynomolgus monkeys. Arthritis Rheum 46:1956-1964. (Pubitemid 34774529)
32. Rosner IA, Goldberg VM, Moskowitz RW. 1986. Estrogens and osteoarthritis. Clin Orthop 213:77-83.
33. Ostergaard K, Andersen CB, Petersen J, et al. 1999. Validity of histopathological grading of articular cartilage from osteoarthritic knee joints. Ann Rheum Dis 58:208-213. (Pubitemid 29191650)
34. Haara MM, Arokoski JPA, Kröger H, et al. 2005. Association of radiological hand osteoarthritis with bone mineral mass: a population study. Rheumatology (Oxford) 44:1549-1554. (Pubitemid 41742474)
35. Sandini L, Arokoski JPA, Jurvelin JS, et al. 2005. Increased bone mineral content but not bone mineral density in the hip in surgically treated knee and hip osteoarthritis. J Rheumatol 32:1951-1957. (Pubitemid 41429026)
36. Sornay-Rendu E, Allard C, Munoz F, et al. 2006. Disc space narrowing as a new risk factor for vertebral fracture. Arthritis Rheum 54:1262-1269. (Pubitemid 43672938)
37. Roux C, Fechtenbaum J, Briot K, et al. 2008. Inverse relationship between vertebral fractures and spine osteoarthritis in postmenopausal women with osteoporosis. Ann Rheum Dis 67:22-28. (Pubitemid 351183312)
38. Muraoka T, Hagino H, Okano T, et al. 2007. Role of subchondral bone in osteoarthritis development: a comparative study of two strains of guinea pigs with and without spontaneously occurring osteoarthritis. Arthritis Rheum 56: 3366-3374. (Pubitemid 47585431)
39. Karsdal MA, Leeming DJ, Dam EB, et al. 2008. Should subchondral bone turnover be targeted when treating osteoarthritis? Osteoarthritis Cartilage 16:638-646.
40. Quasnichka HL, Anderson-MacKenzie JM, Bailey AJ. 2006. Subchondral bone and ligament changes precede cartilage degradation in guinea pig osteoarthritis. Biorheology 43:389-397.
41. Nevitt MC, Lane NE, Scott JC, et al. 1995. Radiographic osteoarthritis of the hip and bone mineral density. The Study of Osteoporotic Fractures Research Group. Arthritis Rheum 38:907-916.
42. Burger H, van Daele PL, Odding E, et al. 1996. Association of radiographically evident osteoarthritis with higher bone mineral density and increased bone loss with age. The Rotterdam Study. Arthritis Rheum 39:81-86. (Pubitemid 26036381)
43. Ayral X. 2001. Injections in the treatment of osteoarthritis. Best Pract Res Clin Rheumatol 15:609-626.