Ischemic preconditioning-induced hyperperfusion correlates with hepatoprotection after liver resection

World Journal of Gastroenterology

Volumn 16, Issue 15, 2010, Pages 1871-1878

  Heizmann, Oleg ^a,b   Meimarakis, Georgios ^b   Volk, Andreas ^b,c   Matz, Daniel ^a   Oertli, Daniel ^a   Schauer, Rolf J ^b  

^a UNIVERSITY HOSPITAL BASEL   (Switzerland)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

Author keywords

Ischemic preconditioning; Liver; Liver blood flow; Reperfusion injury; Surgery

Indexed keywords

ALANINE AMINOTRANSFERASE;

ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTERY PERFUSION; ARTICLE; BILE DUCT BYPASS; BILE LEAKAGE; BLOOD FLOWMETRY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOPPLER FLOWMETER; FATTY LIVER; FEMALE; HEPATIC ARTERY; HUMAN; HUMAN TISSUE; INTRAOPERATIVE PERIOD; ISCHEMIC PRECONDITIONING; LIVER CELL DAMAGE; LIVER DYSFUNCTION; LIVER FIBROSIS; LIVER PERFUSION; LIVER PROTECTION; LIVER RESECTION; LIVER TUMOR; MAJOR CLINICAL STUDY; MALE; PORTAL VEIN BLOOD FLOW; POSTOPERATIVE COMPLICATION; PREDICTION; PRINGLE MANEUVER; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; REPERFUSION; SURGICAL TECHNIQUE; TREATMENT OUTCOME;

EID: 77951469785     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v16.i15.1871     Document Type: Article

References (41)

1. Pringle JH. V. Notes on the Arrest of Hepatic Hemorrhage Due to Trauma. Ann Surg 1908; 48: 541-549
2. Tanabe G, Sakamoto M, Akazawa K, Kurita K, Hamanoue M, Ueno S, Kobayashi Y, Mitue S, Ogura Y, Yoshidome N. Intraoperative risk factors associated with hepatic resection. Br J Surg 1995; 82: 1262-1265
3. Matsumata T, Ikeda Y, Hayashi H, Kamakura T, Taketomi A, Sugimachi K. The association between transfusion and cancer-free survival after curative resection for hepatocellular carcinoma. Cancer 1993; 72: 1866-1871
4. Bilzer M, Gerbes AL. Preservation injury of the liver: mechanisms and novel therapeutic strategies. J Hepatol 2000; 32: 508-515
5. Hannoun L, Borie D, Delva E, Jones D, Vaillant JC, Nordlinger B, Parc R. Liver resection with normothermic ischaemia exceeding 1 h. Br J Surg 1993; 80: 1161-1165
6. Jaeschke H, Farhood A. Neutrophil and Kupffer cell-induced oxidant stress and ischemia-reperfusion injury in rat liver. Am J Physiol 1991; 260: G355-G362
7. Belghiti J, Noun R, Malafosse R, Jagot P, Sauvanet A, Pierangeli F, Marty J, Farges O. Continuous versus intermittent portal triad clamping for liver resection: a controlled study. Ann Surg 1999; 229: 369-375
8. Nuzzo G, Giuliante F, Giovannini I, Tebala GD, de Cosmo G. Hepatic resections in normothermic ischemia. Surgery 1996; 120: 852-858
9. Schauer RJ, Gerbes AL, Vonier D, Meissner H, Michl P, Leiderer R, Schildberg FW, Messmer K, Bilzer M. Glutathi-one protects the rat liver against reperfusion injury after prolonged warm ischemia. Ann Surg 2004; 239: 220-231
10. Glantzounis GK, Yang W, Koti RS, Mikhailidis DP, Seifalian AM, Davidson BR. Continuous infusion of N-acetylcysteine reduces liver warm ischaemia-reperfusion injury. Br J Surg 2004; 91: 1330-1339
11. Wang M, Sakon M, Umeshita K, Okuyama M, Shiozaki K, Nagano H, Dohno K, Nakamori S, Monden M. Prednisolone suppresses ischemia-reperfusion injury of the rat liver by reducing cytokine production and calpain mu activation. J Hepatol 2001; 34: 278-283
12. Murry CE, Jennings RB, Reimer KA. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 1986; 74: 1124-1136
13. Yadav SS, Sindram D, Perry DK, Clavien PA. Ischemic preconditioning protects the mouse liver by inhibition of apoptosis through a caspase-dependent pathway. Hepatology 1999; 30: 1223-1231
14. Clavien PA, Yadav S, Sindram D, Bentley RC. Protective effects of ischemic preconditioning for liver resection performed under inflow occlusion in humans. Ann Surg 2000; 232: 155-162
15. Schauer RJ, Gerbes AL, Vonier D, op den Winkel M, Fraunberger P, Bilzer M. Induction of cellular resistance against Kupffer cell-derived oxidant stress: a novel concept of hepatoprotection by ischemic preconditioning. Hepatology 2003; 37: 286-295
16. Clavien PA, Selzner M, Rüdiger HA, Graf R, Kadry Z, Rousson V, Jochum W. A prospective randomized study in 100 consecutive patients undergoing major liver resection with versus without ischemic preconditioning. Ann Surg 2003; 238: 843-850; discussion 851-852
17. Choukèr A, Schachtner T, Schauer R, Dugas M, Löhe F, Martignoni A, Pollwein B, Niklas M, Rau HG, Jauch KW, Peter K, Thiel M. Effects of Pringle manoeuvre and ischaemic preconditioning on haemodynamic stability in patients undergoing elective hepatectomy: a randomized trial. Br J Anaesth 2004; 93: 204-211
18. Lentsch AB, Kato A, Yoshidome H, McMasters KM, Edwards MJ. Inflammatory mechanisms and therapeutic strategies for warm hepatic ischemia/reperfusion injury. Hepatology 2000; 32: 169-173
19. Jaeschke H. Mechanisms of reperfusion injury after warm ischemia of the liver. J Hepatobiliary Pancreat Surg 1998; 5: 402-408
20. Glanemann M, Vollmar B, Nussler AK, Schaefer T, Neuhaus P, Menger MD. Ischemic preconditioning protects from hepatic ischemia/reperfusion-injury by preservation of microcirculation and mitochondrial redox-state. J Hepatol 2003; 38: 59-66
21. Schauer RJ, Bilzer M, Kalmuk S, Gerbes AL, Leiderer R, Schildberg FW, Messmer K. Microcirculatory failure after rat liver transplantation is related to Kupffer cell-derived oxidant stress but not involved in early graft dysfunction. Transplantation 2001; 72: 1692-1699
22. Klar E, Bredt M, Kraus T, Angelescu M, Mehrabi A, Senninger N, Otto G, Herfarth C. Early assessment of reperfu-sion injury by intraoperative quantification of hepatic micro-circulation in patients. Transplant Proc 1997; 29: 362-363
23. Pannen BH. New insights into the regulation of hepatic blood flow after ischemia and reperfusion. Anesth Analg 2002; 94: 1448-1457
24. Lautt WW. Mechanism and role of intrinsic regulation of hepatic arterial blood flow: hepatic arterial buffer response. Am J Physiol 1985; 249: G549-G556
25. Moher D, Schulz KF, Altman DG. The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials. Ann Intern Med 2001; 134: 657-662
26. Puhl G, Schaser KD, Pust D, Köhler K, Vollmar B, Menger MD, Neuhaus P, Settmacher U. Initial hepatic microcirculation correlates with early graft function in human orthotopic liver transplantation. Liver Transpl 2005; 11: 555-563
27. Suc B, Panis Y, Belghiti J, Fékété F. 'Natural history' of hepatectomy. Br J Surg 1992; 79: 39-42
28. Ploeg RJ, D'Alessandro AM, Knechtle SJ, Stegall MD, Pirsch JD, Hoffmann RM, Sasaki T, Sollinger HW, Belzer FO, Ka-layoglu M. Risk factors for primary dysfunction after liver transplantation--a multivariate analysis. Transplantation 1993; 55: 807-813
29. van Wagensveld BA, van Gulik TM, Gelderblom HC, Scheepers JJ, Bosma A, Endert E, Gouma DJ. Prolonged continuous or intermittent vascular inflow occlusion during hemihepatectomy in pigs. Ann Surg 1999; 229: 376-384
30. Petrowsky H, McCormack L, Trujillo M, Selzner M, Jochum W, Clavien PA. A prospective, randomized, controlled trial comparing intermittent portal triad clamping versus ischemic preconditioning with continuous clamping for major liver resection. Ann Surg 2006; 244: 921-928; discussion 928-930
31. Smyrniotis V, Theodoraki K, Arkadopoulos N, Fragulidis G, Condi-Pafiti A, Plemenou-Fragou M, Voros D, Vassiliou J, Dimakakos P. Ischemic preconditioning versus intermittent vascular occlusion in liver resections performed under selective vascular exclusion: a prospective randomized study. Am J Surg 2006; 192: 669-674
32. Heizmann O, Loehe F, Volk A, Schauer RJ. Ischemic preconditioning improves postoperative outcome after liver resections: a randomized controlled study. Eur J Med Res 2008; 13: 79-86
33. Vollmar B, Glasz J, Leiderer R, Post S, Menger MD. Hepatic microcirculatory perfusion failure is a determinant of liver dysfunction in warm ischemia-reperfusion. Am J Pathol 1994; 145: 1421-1431
34. Chun K, Zhang J, Biewer J, Ferguson D, Clemens MG. Microcirculatory failure determines lethal hepatocyte injury in ischemic/reperfused rat livers. Shock 1994; 1: 3-9
35. Takala J. Determinants of splanchnic blood flow. Br J Anaesth 1996; 77: 50-58
36. Clemens MG, Zhang JX. Regulation of sinusoidal perfusion: in vivo methodology and control by endothelins. Semin Liver Dis 1999; 19: 383-396
37. Edouard AR, Degrémont AC, Duranteau J, Pussard E, Berdeaux A, Samii K. Heterogeneous regional vascular responses to simulated transient hypovolemia in man. Intensive Care Med 1994; 20: 414-420
38. Ezzat WR, Lautt WW. Hepatic arterial pressure-flow auto-regulation is adenosine mediated. Am J Physiol 1987; 252: H836-H845
39. Choukèr A, Martignoni A, Schauer RJ, Rau HG, Volk A, Heizmann O, Dugas M, Messmer K, Peter K, Thiel M. Ischemic preconditioning attenuates portal venous plasma concentrations of purines following warm liver ischemia in man. Eur Surg Res 2005; 37: 144-152
40. Demetris AJ, Kelly DM, Eghtesad B, Fontes P, Wallis Marsh J, Tom K, Tan HP, Shaw-Stiffel T, Boig L, Novelli P, Planinsic R, Fung JJ, Marcos A. Pathophysiologic observations and histopathologic recognition of the portal hyperperfusion or small- for-size syndrome. Am J Surg Pathol 2006; 30: 986-993
41. Rosen HR, Martin P, Goss J, Donovan J, Melinek J, Rudich S, Imagawa DK, Kinkhabwala M, Seu P, Busuttil RW, Shackleton CR. Significance of early aminotransferase elevation after liver transplantation. Transplantation 1998; 65: 68-72