INOS-targeted 10-23 dnazyme reduces lps-induced systemic inflammation and mortality in mice

Shock

Volumn 33, Issue 5, 2010, Pages 493-499

  Verma, Nandini ^a   Tripathi, Subhash K ^a   Chaudhury, Indrajit ^a   Das, Hasi R ^a   Das, Rakha H ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

Author keywords

BALB c mouse; DNAzyme; Leukocytic infiltration; NO; Peritoneal macrophage; Proinflammatory cytokines

Indexed keywords

CYTOKINE; DEOXYRIBOZYME; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA; AUTACOID; NOS2 PROTEIN, MOUSE; RNA-CLEAVING DNA 10-23; SINGLE STRANDED DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL COUNT; CELL CULTURE; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; EDEMA; FEMALE; GENE REPRESSION; HISTOPATHOLOGY; INJECTION; LEUKOCYTE; MORTALITY; MOUSE; NONHUMAN; PERITONEUM LAVAGE; PERITONEUM MACROPHAGE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RISK REDUCTION; SEPSIS; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; ANIMAL; ANTAGONISTS AND INHIBITORS; BAGG ALBINO MOUSE; BIOSYNTHESIS; BLOOD; CHEMICALLY INDUCED; GENE SILENCING; GENETICS; INFLAMMATION; METABOLISM; PATHOLOGY; TOXICITY;

ANIMALS; CELLS, CULTURED; DNA, CATALYTIC; DNA, SINGLE-STRANDED; FEMALE; GENE KNOCKDOWN TECHNIQUES; INFLAMMATION; INFLAMMATION MEDIATORS; INTERLEUKIN-12; LIPOPOLYSACCHARIDES; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II;

EID: 77951432651     PISSN: 10732322     EISSN: None     Source Type: Journal    
DOI: 10.1097/SHK.0b013e3181c4ecbb     Document Type: Article

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