Inhibition of lipopolysaccharide-inducible nitric oxide synthase and IL-1β through suppression of NF-κB activation by 3-(1′-1′-dimethyl-allyl)-6-hydroxy-7-methoxy-coumarin isolated from Ruta graveolens L.

European Journal of Pharmacology

Volumn 560, Issue 1, 2007, Pages 69-80

  Raghav, Sunil Kumar ^a   Gupta, Bhawna ^a   Shrivastava, Anju ^b   Das, Hasi Rani ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b UNIVERSITY OF DELHI   (India)

Author keywords

Anti inflammatory effect; IkB; IL 1 ; iNOS; NF B; Ruta graveolens

Indexed keywords

6 HYDROXY 7 METHOXY 3 (2 METHYLBUT 3 EN 2YL) 2H CHROMEN 2 ONE; COMPLEMENTARY DNA; COUMARIN DERIVATIVE; ETHER; FAS ASSOCIATED DEATH DOMAIN PROTEIN; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; INTERLEUKIN 1BETA; ISOSCOPOLETIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRITE; QUERCETIN; RG 001; RUTA GRAVEOLENS EXTRACT; RUTOSIDE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CELL CULTURE; CONTROLLED STUDY; ELECTROSPRAY MASS SPECTROMETRY; ENDOTOXEMIA; ENZYME LINKED IMMUNOSORBENT ASSAY; FOURIER TRANSFORMATION; HERBAL MEDICINE; INDIA; INFRARED SPECTROSCOPY; MACROPHAGE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MEDICINAL PLANT; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEOTIDE SEQUENCE; PHYTOTHERAPY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RUTACEAE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; BLOTTING, WESTERN; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARINS; CYTOKINES; DISEASE MODELS, ANIMAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; GENE EXPRESSION; I-KAPPA B PROTEINS; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, INBRED BALB C; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PHYTOTHERAPY; PLANT EXTRACTS; RUTA;

EID: 33847329639     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2007.01.002     Document Type: Article

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