Mechanism underlying hypokalemia induced by trimethyltin chloride: Inhibition of H+/K+-ATPase in renal intercalated cells

Toxicology

Volumn 271, Issue 1-2, 2010, Pages 45-50

  Tang, Xiaojiang ^a   Yang, Xiaojun ^a   Lai, Guanchao ^a   Guo, Jinhui ^b   Xia, Lihua ^a   Wu, Banghua ^a   Xie, Yuxuan ^a   Huang, Ming ^a   Chen, Jiabin ^a   Ruan, Xiaolin ^a   Sui, Gang ^a   Ge, Yichen ^a   Zuo, Wulin ^b   Zhao, Na ^a   Zhu, Guanghua ^a   Zhang, Jinxin ^b   Li, Laiyu ^a   Zhou, Wenliang ^b  

^a Guangdong Poison Control Center   (China)

^b SUN YAT SEN UNIVERSITY   (China)

Author keywords

H+ K+ ATPase; Hypokalemia; Renal intercalated cells; Trimethyltin chloride (TMT)

Indexed keywords

HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; MESSENGER RNA; POTASSIUM CHANNEL; TRIMETHYLTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PH; CELL PH; CHANNEL GATING; CONTROLLED STUDY; CREATININE URINE LEVEL; GENE EXPRESSION; HYPOKALEMIA; KIDNEY CELL; KIDNEY TUBULE ABSORPTION; NONHUMAN; POTASSIUM BLOOD LEVEL; POTASSIUM CONDUCTANCE; POTASSIUM TRANSPORT; POTASSIUM URINE LEVEL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; URINE PH;

ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; H(+)-K(+)-EXCHANGING ATPASE; HYDROGEN-ION CONCENTRATION; HYPOKALEMIA; KIDNEY DISEASES; KIDNEY TUBULES, COLLECTING; POTASSIUM; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRIMETHYLTIN COMPOUNDS;

ANIMALIA; RATTUS;

EID: 77951298164     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2010.02.013     Document Type: Article

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