A microtubule associated protein (hNUDC) binds to the extracellular domain of thrombopoietin receptor (Mpl)

Journal of Cellular Biochemistry

Volumn 96, Issue 4, 2005, Pages 741-750

  Pan, Rui Min ^a   Yang, Yan ^a   Wei, Ming Xu ^a   Yu, Xiao Bin ^a   Ge, Yi Chen ^a   Xu, Peilin ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Dynein; hNUDC; Megakaryocyte; Microtubules; TPO

Indexed keywords

FUNGAL PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; THROMBOPOIETIN RECEPTOR;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; ASPERGILLUS NIDULANS; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MEGAKARYOCYTE; MICROTUBULE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN LOCALIZATION; TWO HYBRID SYSTEM;

BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELLS, CULTURED; HUMANS; IMMUNOPRECIPITATION; MEGAKARYOCYTES; NUCLEAR PROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; RECEPTORS, CYTOKINE; RECEPTORS, THROMBOPOIETIN; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION; TUBULIN; TWO-HYBRID SYSTEM TECHNIQUES;

ANIMALIA; EMERICELLA NIDULANS;

EID: 27644589258     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20573     Document Type: Article

References (32)

1. Alexander WS, Metcalf D, Dunn AR. 1995. Point mutations within a dimer interface homology domain of c-Mpl induce constitutive receptor activity and tumorigenicity. EMBO J 14:5569-5578.
2. Alexander WS. 1999. Thrombopoietin and the c-Mpl receptor: Insights from gene targeting. Int J Biochem Cell Biol 31:1027-1035.
3. Aumais JP, Tunstead JR, McNeil RS, Schaar BT, McConnell SK, Lin SH, Clark GD, Yu-Lee LY. 2001. NudC associates with Lis1 and the dynein motor at the leading pole of neurons. J Neurosci 21:1-7.
4. Aumais JP, Williams SN, Luo W, Nishino M, Caldwell KA, Caldwell GA, Lin SH, Yu-Lee LY. 2003. Role for NudC, a dynein-associated nuclear movement protein, in mitosis and cytokinesis. J Cell Sci 116:1991-2003.
5. Bartley TD, Bogenberger J, Hunt P, Li Y, Lu HS, Martin F, Chang M, Samal B, Nichol JL, Swift S, Johnson MJ, Hsu R, Parker VP, Suggs S, Skrine JD, Merewether LA, Clogston C, Hsu E, Hokom MM, Hornkohl A, Choi E, Pangelinan M, Sun Y, Mar V, McNinch J, Simonet L, Jacobsen F, Xie C, Shutter J, Chute H, Basu R, Selander L, Trollinger D, Sieu L, Padilla D, Trail G, Elliott G, Izumi R, Covey T, Crouse J, Garcia A, Xu W, Del Castillo J, Biron J, Cole S, Hu MC, Pacifici R, Ponting I, Saris C, Wen D, Yung YP, Lin H, Bosselman RA. 1994. Identification and cloning of a megakaryocyte growth and development factor that is a ligand for the cytokine receptor Mpl-Cell 77:1117-1124.
6. Brandt JE, Bhalla K, Hoffman R. 1994. Effects of interleukin-3 and c-kit ligand on the survival of various classes of human hematopoietic progenitor cells. Blood 15:1507-1514.
7. Broudy VC, Lin NL, Sabath DF, Papayannopoulou T, Kaushansky K. 1997. Human platelets isplay high-affinity receptors for thrombopoietin. Blood 89:1896-1904.
8. Bunting S, Widmer R, Lipari T, Rangell L, Steinmetz H, Carver-Moore K, Moore MW, Keller GA, de Sauvage FJ. 1997. Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin. Blood 90:3423-3429.
9. Burstein SA, Mei RL, Henthorn J, Friese P, Turner K. 1992. Leukemia inhibitory factor and interleukin-11 promote maturation of murine and human megakaryocytes-in vitro. J Cell Physiol 153:305-312.
10. de Sauvage FJ, Hass PE, Spencer SD, Malloy BE, Gurney AL, Spencer SA, Darbonne WC, Henzel WJ, Wong SC, Kuang W, Oles KJ, Hultgren B, Solberg LAJ, Goeddel DV, Eaton DL. 1994. Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand. Nature 369:533-538.
11. de Sauvage FJ, Carver-Moore K, Luoh SM, Ryan A, Dowd M, Eaton DL, Moore MW. 1996. Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin. J Exp Med 183:651-656.
12. Espanol I, Hernandez A, Cortes M, Mateo J, Pujol-Moix-N. 1999. Patients with thrombocytosis have normal or slightly elevated thrombopoietin levels. Haematologica 84:312-316.
13. Feese MD, Tamada T, Kato Y, Maeda Y, Hirose M, Matsukura Y, Shigematsu H, Muto T, Matsumoto A, Watarai H, Ogami K, Tahara T, Kato T, Miyazaki H, Kuroki R. 2004. Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment. Proc Nat Acad Sci USA 101:1816-1821.
14. Goode BL, Drubin DG, Barnes G. 2000. Functional cooperation between the microtubule and actin cytoskeletons. Curr Opinion Cell Biol 12:63-71.
15. Hartwig J, Italiano J, Jr. 2003. The birth of the platelet. J Thromb Haemost 1:1580-1586.
16. Ishibashi T, Kimura H, Uchida T, Kariyone S, Friese P, Burstein SA. 1989. Human interleukin 6 is a direct promoter of maturation of megakaryocytes in vitro. Proc Natl Acad Sci USA 86:5953-5957.
17. Kaushansky K, O'Hara PJ, Berkner K, Segal GM, Hagen FS, Adamson JW. 1986. Genomic cloning, characterization, and multilineage growth-promoting activity of human granulocyte-macrophage colony-stimulating factor. Proc Natl Acad Sci USA 83:3101-3105.
18. Lok S, Kaushansky K, Holly RD, Kuijper JL, Lofton-Day CE, Oort PJ, Grant FJ, Heipel MD, Burkhead SK, Kramer JM, Bell LA, Sprecher CA, Blumberg H, Johnson R, Prunkard D, Ching AFT, Mattewes SL, Bailey MC, Forstrom JW, Buddle MM, Osborn SG, Evans SJ, Sheppard PO, Presnell SR, O'Hara PJ, Hagen FS, Roth GJ, Foster DC. 1994. Cloning and expression of murine thrombopoietin cDNA and stimulation of platelet production in vivo. Nature 369:565-568.
19. Matsumoto N, Ledbetter DH. 1999. Molecular cloning and characterization of the human HUDC gene. Hum Genet 104:498-504.
20. Miller BA, Zhang MY, Gocke CD, De Souza C, Osmani AH, Lynch C, Davies J, Bell L, Osmani SA. 1999. A homolog of the fungal nuclear migration gene nudC is involved in normal and malignant human hematopoiesis. Exp Hematol 27:742-750.
21. Nagahisa H, Nagata Y, Ohnuki T, Osada M, Nagasawa T, Abe T, Todokoro K. 1996. Bone marrow stromal cells produce thrombopoietin and stimulate megakaryocyte growth and maturation but suppress proplatelet formation. Blood 87:1309-1316.
22. Nagata Y, Muro Y, Todokoro K. 1998. Thrombopoietin-induced polyploidization of bone marrow megakaryocytes is due to a unique regulatory mechanism in late mitosis. J Cell Biol 139:449-457.
23. Osmani AH, Osmani SA, Morris NR. 1990. The molecular cloning and identification of a gene-product specifically required for nuclear movement in Aspergillus nidulans. J Cell Biol 111:543-551.
24. Paul SR, Bennett F, Calvetti JA, Kelleher K, Wood CR, O'Hara RM, Jr., Cleary AC, Sibley B, Clark SC, Williams DA, Yang Y. 1990. Molecular cloning of a cDNA encoding interleukin 11, a stromal cell-derived lymphopoietic and hematopoietic cytokine. Proc Natl Acad Sci USA 87:7512-7516.
25. Rothwell SW, Calvert VS. 1997. Activation of human platelets causes post-translational modifications to cytoplasmic dynein. Thromb Haemost 78:910-918.
26. Sabath DF, Kaushansky K, Broudy VC. 1999. Deletion of the extracellular membrane-distal cytokine receptor homology module of Mpl results in constitutive cell growth and loss of thrombopoietin binding. Blood 94:365-367.
27. Tanaka R, Koike K, Imai T, Shiohara M, Kubo T, Amano Y, Komiyama A, Nakahata T. 1992. Stem-cell factor enhances proliferation, but not maturation, of murine megakaryotic progenitor in serum-free culture. Blood 80:1743-1749.
28. Welte MA. 2004. Bidirectional transport along microtubules. Curr Biol 14:525-537.
29. Wendling F, Maraskovsky E, Debili N, Florindo C, Teepe M, Titeux M, Methia N, Breton-Gorius J, Cosman D, Vainchenker W. 1994. cMpl ligand is a humoral regulator of megakaryocytopoiesis. Nature 369:571-574.
30. Xiang X, Beckwith SM, Morris NR. 1994. Cytoplasmic dynein is involved in nuclear migration in Aspergillus nidulans. Proc Natl Acad Sci USA 91:2100-2104.
31. Zhang MY, Huang NN, Clawson GA, Osmani SA, Pan W, Xin P, Razzaque MS, Miller BA. 2002. Involvement of the fungal nuclear migration gene nudC human homolog in cell proliferation and mitotic spindle formation. Exp Cell Res 273:73-84.
32. Zhang Q, Pan RM, Ge YC, Xu P. 2004. Expression of the soluble extracellular domain of human thrombopoietin receptor (Mpl) using a maltose-binding protein-affinity fusion system. Biol Pharm Bull 27:219-221.