H+ -K+ -ATPases: Regulation and role in pathophysiological states

American Journal of Physiology - Renal Physiology

Volumn 276, Issue 6 45-6, 1996, Pages

  Silver, Randi B ^b   Soleimani, Manoocher ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b NONE

Author keywords

Acid base homeostasis; Kidney; Potassium depletion; Proton potassium adenosinetriphosphatase; Sodium depletion

Indexed keywords

BICARBONATE; CHLORIDE ION; HYDROGEN POTASSIUM ADENOSINE TRIPHOSPHATASE; POTASSIUM ION; PROTON; SODIUM ION;

ACID BASE BALANCE; COLON MUCOSA; HUMAN; KIDNEY COLLECTING TUBULE; NONHUMAN; PATHOPHYSIOLOGY; POTASSIUM BALANCE; PRIORITY JOURNAL; PROTON SODIUM EXCHANGE; PROTON TRANSPORT; REVIEW; SODIUM ABSORPTION; SODIUM BALANCE; STOMACH EPITHELIUM;

EID: 0033000386     PISSN: 03636127     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (86)

1. +-ATPase α-subunit in rat kidney. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F99-F109, 1995.
2. +-ATPase alpha 2-subunit gene in renal medulla. Am. J. Physiol. 271 (Renal Fluid Electrolyte Physiol. 40): F314-F321, 1996.
3. +-depletion (Abstract). J. Am. Soc. Nephrol. In press.
4. Amlal, H., Z. Wang, and M. Soleimani. Potassium depletion downregulates chloride-absorbing transporters in rat kidney. J. Clin. Invest. 101: 1045-1054, 1998.
5. i: contributions of H-KATPase and bafilomycin-A1-sensitive H-ATPase. Am. J. Physiol. 267 (Renal Fluid Electrolyte Physiol. 36): F450-F458, 1994.
6. Baird, N. R., H. Zaun, Z. Wang, and M. Soleimani. The effect of DOCAand potassium depletion on mRNA expression of ROMK isoforms (Abstract). J. Am. Soc. Nephrol. 8: 28, 1997.
7. Bastani, B. Colocalization of H-ATPase and H-K ATPase immunoreactivity in the rat kidney. J. Am. Soc. Nephrol. 5: 1476-1482, 1995.
8. Bengele, H, E. R. McNamara, J. H. Schwartz, and E. A. Alexander. Acidification adaptation along the inner medullary collecting duct. Am. J. Physiol. 255 (Renal Fluid Electrolyte Physiol. 24): F1155-F1159, 1988.
9. Buffin-Meyer, B., M. Younes-Ibrahim, C. Barlet-Bas, L. Chevel, S. Marsy, and A. Doucet. K depletion modifies properties of SCH-28080-sensitive K-ATPase in rat collecting duct. Am. J. Physiol. 272 (Renal Physiol. 41): F124-F131, 1997.
10. Campbell-Thompson, M. L., J. W. Verlander, K. A. Curran, W. G. Campbell, B. D. Cain, C. S. Wingo, and J. E. McGuigan. In situ hybridization of H-K- ATPase β-subunit mRNA in rat and rabbit kidney. Am. J. Physiol. 269 (Renal Fluid Electrolyte Physiol. 38): F345-F354, 1995.
11. Capasso, G., P. Jaeger, G. Giebisch, V. Guckian, and G. Malnic. Renal bicarbonate reabsorption. II. Distal tubule load dependence and effect of hypokalemia. J. Clin. Invest. 80: 409-414, 1987.
12. Constantinescu, A., R. B. Silver, and L. M. Satlin. H-K-ATPase activity in PNA-binding intercalated cells of newborn rabbit cortical collecting duct. Am. J. Physiol. 272 (Renal Physiol. 41): F167-F177, 1997.
13. Cougnon, M., P. Bouyer., and F. Jaisser. Does the colonic H,K-ATPase also act as an Na,K-ATPase. Proc. Natl. Acad. Sci. USA. In press.
14. +-ATPase. J. Biol. Chem. 267: 13740-13748, 1996.
15. +-ATPase and messenger RNA expression in distal colon, kidney and uterus. J. Biol. Chem. 267: 13740-13748, 1992.
16. + deprivation. Am. J. Physiol. 260 (Renal Fluid Electrolyte Physiol. 29): F800-F805, 1991.
17. + activated ATPase activities in rat distal colon. Am. J. Physiol. 261 (Gastrointest. Liver Physiol. 24): G1005-G1011, 1991.
18. Doucet, A., and S. Marsy. Characterization of K-ATPase in ion transport in the kidney. Am. J. Physiol. 252 (Renal Fluid Electrolyte Physiol. 21): F418-F423, 1987.
19. +- ATPase expression in kidney. Am. J. Physiol. 269 (Renal Fluid Electrolyte Physiol. 38): F500-F507, 1995.
20. Eiam-Ong, S., N. A. Kurtzman, and S. Sabatini. Regulation of collecting tubule adenosine triphosphates by aldosterone and potassium. J. Clin. Invest. 91: 2385-2392, 1992.
21. Eiam-Ong, S., M. E. Laski, N. A. Kurtzman, and S. Sabatini. Effect of respiratory acidosis and respiratory alkalosis on renal transport enzymes. Am. J. Physiol. 267 (Renal Fluid Electrolyte Physiol. 36): F390-F399, 1994.
22. Fernandez, R., M. J. Lopes, R. F. de Lira, W. F. Dantas, E. J. Cragoe, Jr., and G. Malnic. Mechanism of acidification along cortical distal tubule of the rat. Am. J. Physiol. 266 (Renal Fluid Electrolyte Physiol. 35): F218-F226, 1994.
23. Galla, J. H., D. N. Bonduris, K. A. Kirk, and R. G. Luke. Effect of dietary NaCl on chloride uptake in rat collecting duct. Am. J. Physiol. 251 (Renal Fluid Electrolyte Physiol. 20): F454-F459, 1986.
24. + transport. J. Exp. Biol. 172: 205-218, 1992.
25. Garg, L. C., and N. Narang. Ouabain-insensitive K-ATPase in distal nephron segments of the rabbit. J. Clin. Invest. 81: 1204-1208, 1988.
26. Garty, H., and L. G. Palmer. Epithelial sodium channels: function, structure, and regulation. Physiol. Rev. 77: 359-396, 1997.
27. +-ATPase activity in rat collecting duct segments. Am. J. Physiol. 262 (Renal Fluid Electrolyte Physiol. 31): F692-F695, 1992.
28. Gifford, J. D., M. W. Ware, S. Crowson, and G. E. Shull. Expression of a putative rat distal colonic H,K ATPase mRNA in rat kidney: effect of respiratory acidosis (Abstract). J. Am. Soc. Nephrol. 2: 700, 1991.
29. 4 by rat medullary thick ascending limb: inhibition by potassium. Am. J. Physiol. 255 (Renal Fluid Electrolyte Physiol. 24): F78-F87, 1988.
30. Gopal Krishna, G., and P. Chusid, and R. Hoeldtke. Mild potassium depletion provokes renal sodium retention. J. Lab. Clin. Med. 109: 724-730, 1987.
31. Gopal Krishna, G., and S. C. Kapoor. Potassium supplementation ameliorates mineralocorticoid-induced sodium retention. Kidney Int. 43: 1097-1103, 1993.
32. i cells. Am. J. Physiol. 273 (Cell Physiol. 42): C558-C571, 1997.
33. +-ATPases: molecular and functional properties. Am. J. Physiol. 276 (Renal Physiol. 45): F812-F824, 1999.
34. + diet and corticosteroids in rat distal colon and kidney. Am. J. Physiol. 270 (Cell Physiol. 39): C679-C687, 1996.
35. Jaisser, F., J. D. Horisberger, K. Geering, and B. C. Rossier. Mechanism of urinary K and H excretion: primary structure and functional expression of a novel H,K-ATPase. J. Cell Biol. 6: 1421-1431, 1993.
36. +-ATPase of rat inner medullary collecting duct in primary culture. Am. J. Physiol. 265 (Renal Fluid Electrolyte Physiol. 34): F698-F704, 1993.
37. Kone, B. C. Renal H,K-ATPase: structure, function, and regulation. Miner. Electrolyte Metab. 22: 349-365, 1996.
38. +-ATPase α2 subunit. J. Biol. Chem. 273: 2543-2552, 1998
39. Kraut, J. A., J. Hiura, M. Besancon, A. Smolka, G. Sachs, and D. Scott. Effect of hypokalemia on the abundance of HKα1 and HKα2 protein in the rat kidney. Am. J. Physiol. 272 (Renal Physiol. 41): F744-F750, 1997.
40. + depletion. Am. J. Physiol. 270 (Renal Fluid Electrolyte Physiol. 39): F116-F122, 1996.
41. Lee, J., V. M. Rajendran, A. S. Mann, M. Kashgarian, and H. J. Binder. Functional expression and segmental localization of rat colonic K-ATPase. J. Clin. Invest. 96: 2002-2008, 1995.
42. Long, J. F., P. J. Chiu, M. J. Derelanko, and M. Steinberg. Gastric antisecretory and cytoprotective activities of SCH 28080. J. Pharmacol. Exp. Ther. 226: 114-120, 1983.
43. Luke, R. G., and H. Levtin. Impaired renal conservation of chloride and the acid base changes associated with potassium depletion in the rat. Clin. Sci. (Colch.) 32: 511-526, 1967.
44. Luke, R. G., F. S. Wright, N. Fowler, M. Kashgarian, and G. H. Giebisch. Effect of potassium depletion on renal tubular chloride transport in the rat. Kidney Int. 14: 414-427, 1978.
45. Mannitius, A., H. Levitin, D. Beck, and F. H. Epstein. On the mechanism of impairment of renal concentrating ability in potassium deficiency. J. Clin. Invest. 39: 684-692, 1960.
46. + depletion. Pflügers Arch. 432: 494-500, 1996.
47. + deprivation in colonic H,K-ATPase-deficient mice. J. Clin. Invest. 101: 536-542, 1998.
48. Muto, S., K. Yasoshima, K. Yoshitomi, and Y. Asano. Electrophysiological identification of a- and b- intercalated cells and their distribution along the rabbit distal nephron segments. J. Clin. Invest. 86: 1829-1839, 1990.
49. t (Abstract). J. Am. Soc. Nephrol. 8: 8, 1997.
50. 3 reabsorption in IMCDt in potassium depletion. Kidney Int. 54: 1233-1239, 1998
51. 3 reabsorption in outer medullary collecting duct by activation of colonic H-K-ATPase. Am. J. Physiol. 274 (Renal Physiol. 43): F687-F692, 1998.
52. Okusa, M. D., R. J. Unwin, H. Velazquez, and G. Giebisch. Active potassium absorption by the renal distal tubule. Am. J. Physiol. 262 (Renal Fluid Electrolyte Physiol. 31): F488-F493, 1992.
53. i regulation in inner medullary collecting duct cells in culture. Am. J. Physiol. 270 (Renal Fluid Electrolyte Physiol. 39): F852-F861, 1996.
54. Palmer, L. G., and G. Frindt. Regulation of apical membrane Na and K channels in rat renal collecting tubules by aldosterone. Semin. Nephrol. 12: 37-43, 1992.
55. Rector, F. C., Jr., H. A. Bloomer, and D. W. Seldin. Effect of potassium deficiency on the reabsorption of bicarbonate in the proximal tubule of the rat kidney. J. Clin. Invest. 43: 1976-1982.
56. Rosenbaum, B., M. J. Kinney, F. C. Scudder, V. A. DiScala, and R. M. Stein. Effect of potassium depletion on renal tubular sodium and water reabsorption in the dog. Am. J. Physiol. 222: 928-937, 1972.
57. Sangan, P., V. M. Rajendran, A. S. Mann, M. Kashgarian, and H. J. Binder. Regulation of colonic H-K ATPase in large intestine and kidney by dietary Na depletion and dietary K depletion. Am. J. Physiol. 272 (Cell Physiol. 41): C685-C696, 1997.
58. Schwartz, G. J., and M. B. Burg. Mineralocorticoid effects on cation transport by cortical collecting tubules in vitro. Am. J. Physiol. 235 (Renal Fluid Electrolyte Physiol. 4): F576-F585, 1978.
59. Seldin, D. W., and F. C. Rector. The generation and maintenance of metabolic alkalosis. Kidney Int. 1: 306-321, 1972.
60. +)-ATPase. J. Biol. Chem. 261: 16788-16791, 1986.
61. Silver, R. B., H. Choe, and G. Frindt. Low NaCl diet increases H-K ATPase in intercalated cells from rat cortical collecting duct. Am. J. Physiol. 275 (Renal Physiol. 44): F94-F102, 1998.
62. Silver, R. B., and G. Frindt. Functional identification of H-K-ATPase in intercalated cells of cortical collecting tubule. Am. J. Physiol. 264 (Renal Fluid Electrolyte Physiol. 33): F259-F266, 1993.
63. Silver, R. B., G. Frindt, P. Mennitt, and L. Satlin. Characterization and regulation of H-K ATPase in intercalated cells of rabbit cortical collecting duct. J. Exp. Zool. 279: 443-455, 1997.
64. Silver, R. B., P. A. Mennitt, and L. M. Satlin. Stimulation of apical H-K-ATPase in intercalated cells of cortical collecting duct with chronic metabolic acidosis. Am. J. Physiol. 270 (Renal Fluid Electrolyte Physiol. 39): F539-F547, 1996.
65. 3 cotransport in rat renal cortex. J. Clin. Invest. 86: 1076-1083, 1990.
66. + exchangers in health and disease processes. J. Investig. Med. 43: 419-430, 1995.
67. Stokes, J. B. Potassium secretion by cortical collecting tubule: relation to sodium reabsorption, luminal sodium concentration and transepithelial voltage. Am. J. Physiol. 241 (Renal Fluid Electrolyte Physiol. 10): F395-F402, 1981.
68. Swarts, H. G. P., C. H. Klaassen, F. M. Schuurmans Stekhoven, and J. H. H. De Pont. Sodium acts as a potassium analog on gastric H,K-ATPase. J. Biol. Chem. 270: 7890-7895, 1995.
69. Tannen, R. L. Relationship of renal ammonia production and potassium homeostasis. Kidney Int. 11: 453-456, 1977.
70. Tomita, K., J. J. Pisano, and M. A. Knepper. Control of sodium and potassium transport in the cortical collecting tubule of the rat. Effects of bradykinin, vasopressin and deoxycorticosterone. J. Clin. Invest. 76: 132-136, 1985.
71. Tsuchiya, K., G. Giebisch, and P. A. Welling. Molecular characterization and distribution of H/K-ATPase catalytic subunit gene products in the kidney (Abstract). J. Am. Soc. Nephrol. 4: 881, 1993.
72. t (Abstract). J. Am. Soc. Nephrol. 8: 12, 1997.
73. +-ATPase mediates net acid secretion in rat terminal inner medullary collecting duct. Am. J. Physiol. 271 (Renal Fluid Electrolyte Physiol. 40): F1037-F1044, 1996.
74. +-ATPase and acid secretion by SCH 28080, a substituted pyridyl(1,2a)imidazole. J. Biol. Chem. 262: 2077-2084, 1987.
75. Wang, T., G. Malnic, G. Giebisch, and Y. L. Chan. Renal bicarbonate reabsorption in thg rat. IV. Bicarbonate transport mechanisms in the early and late distal tubule. J. Clin. Invest. 91: 2776-2784, 1993.
76. Wang, Z., N. Baird, H. Shumaker, and M. Soleimani. Potassium depletion and acid-base transporters in rat kidney: differential effect of hypophysectomy. Am. J. Physiol. 272 (Renal Physiol. 41): F736-F743, 1997.
77. Wang, Z., H. Rabb, T. Craig, C. Burnham, G. Shull, and M. Soleimani. Ischemic-reperfusion injury in the kidney: overexpression of colonic H-K-ATPase and suppression of NHE-3. Kidney Int. 51: 1106-1115, 1997.
78. +-ATPase (cHKA) upregulation in Na depletion hypotonicity: possible roles in acid-base homeostasis (Abstract). J. Am. Soc. Nephrol. 8: 13, 1997.
79. +-ATPase in rabbit cortical collecting duct β-type intercalated cell. Am. J. Physiol. 270 (Renal Fluid Electrolyte Physiol. 39): F518-F530, 1996.
80. Wingo, C. S. Active proton secretion and potassium absorption in the rabbit outer medullary collecting duct. J. Clin. Invest. 84: 361-365, 1989.
81. Wingo, C. S., and F. Armitage. Rubidium absorption and proton secretion by rabbit outer medullary collecting duct via H-K-ATPase. Am. J. Physiol. 263 (Renal Fluid Electrolyte Physiol. 32): F849-F857, 1992.
82. Wingo, C. S., K. M. Madsen, A. Smolka, and C. C. Tisher. H-K-ATPase immunoreactivity in cortical and outer medullary collecting duct. Kidney Int. 38: 985-990, 1990.
83. Wingo, C. S. and. A. J. Smolka. Function and structure of H-K-ATPase in the kidney. Am. J. Physiol. 269 (Renal Fluid Electrolyte Physiol. 38): F1-F16, 1995.
84. Younes-Ibraham, M., C. Barlet-Bas, B. Buffin-Meyer, L. Cheval, R. Rajerison, and A. Doucet. Ouabain-sensitive and ouabain-insensitive K-ATPases in rat nephron: effect of K depletion. Am. J. Physiol. 268 (Renal Fluid Electrolyte Physiol. 37): F1140-F1147, 1995.
85. Zhou, X., and C. S. Wingo. Mechanisms of rubidium permeation by rabbit cortical collecting duct during potassium restriction. Am. J. Physiol. 263 (Renal Fluid Electrolyte Physiol. 32): F1134-F1141, 1992.
86. 2 in rabbit CCD: role of an apical SCH-28080 and Ba-sensitive mechanism. Am. J. Physiol. 267 (Renal Fluid Electrolyte Physiol. 36): F114-F120, 1994.