Application of red laser video-rate scanning confocal microscopy to in vivo assessment of tubular function in the rat: Selective action of diuretics on tubular diameter

Experimental Physiology

Volumn 89, Issue 2, 2004, Pages 181-185

  Simeoni, M ^a,b,c   Boyde, A ^a   Shirley, David G ^b,d   Capasso, G ^c   Unwin, R J ^b  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c SECOND UNIVERSITY OF NAPLES   (Italy)

^d MIDDLESEX HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIURETIC AGENT; FUROSEMIDE; HYDROCHLOROTHIAZIDE; MANNITOL;

ARTICLE; CELL STRUCTURE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; IMAGE ANALYSIS; IMAGING SYSTEM; IN VIVO STUDY; KIDNEY DISTAL TUBULE; KIDNEY PROXIMAL TUBULE; LASER MICROSCOPY; MALE; NEPHRON; NONHUMAN; RAT; SCANNING ELECTRON MICROSCOPY;

EID: 1642334204     PISSN: 09580670     EISSN: None     Source Type: Journal    
DOI: 10.1113/expphysiol.2003.002643     Document Type: Article

References (16)

1. Andrews PM (1994). The histopathology of kidney uriniferous tubules as revealed by non-invasive confocal vital microscopy. Scanning 16, 174-181.
2. Blatter LA & Niggli E (1998). Confocal near-membrane detection of calcium in cardiac myocytes. Cell Calcium 23, 269-279.
3. Boyde A, Capasso G & Unwin RJ (1998). Conventional and confocal epi-reflection and fluorescence microscopy of the rat kidney in vivo. Exp Nephrol 6, 398-408.
4. Buerkert J, Martin D, Prasad J & Trigg D (1981). Role of deep nephrons and the terminal collecting duct in a mannitol-induced diuresis. Am J Physiol 240, F411-F422.
5. Dunn KW, Sandoval RM, Kelly KJ, Dagher PC, Tanner GA, Atkinson SJ, Bacallao RL & Molitoris BA (2002). Functional studies of the kidney of living animals using multicolor two-photon microscopy. Am J Physiol Cell Physiol 283, C905-C916.
6. Dunn KW, Sandoval RM & Molitoris BA (2003). Intravital imaging of the kidney using multiparameter multiphoton microscopy. Nephron Exp Nephrol 94, E7-E11.
7. Greenwood SL, White SJ & Green R (1990). The effect of loop diuretics on fluid reabsorption from the rat proximal convoluted tubule. Exp Physiol 75, 375-382.
8. Lang F (1987). Osmotic diuresis. Renal Physiol 10, 160-173.
9. Leyssac PP, Holstein-Rathlou N-H & Skøtt O (2000). Renal blood flow, early distal sodium, and plasma rennin concentrations during osmotic diuresis. Am J Physiol 279, R1268-R1276.
10. Okusa MD & Ellison DH (2000). Physiology and pathophysiology of diuretic action. In The Kidney. Physiology and Pathophysiology, ed. Seldin DW and Giebisch G, pp. 2877-2922. Lippincott Williams & Wilkins, Philadelphia.
11. Petroll WM, Jester JV & Cavanagh HD (1994). In vivo confocal imaging: General principles and applications. Scanning 16, 131-149.
12. Shirley DG, Walter SJ & Sampson B (1992). A micropuncture study of renal lithium reabsorption: Effects of amiloride and furosemide. Am J Physiol 263, F1128-F1133.
13. Velázquez H (1987). Thiazide diuretics. Renal Physiol 10, 184-197.
14. Verhulst A, Persy VP, van Rompay AR, Verstrepen WA, Helbert MF & de Broe ME (2002). Osteopontin synthesis and localization along the human nephron. J Am Soc Nephrol 13, 1210-1218.
15. Walter SJ & Shirley DG (1991). Effect of frusemide on lithium clearance and proximal tubular reabsorption in anaesthetised rats. J Physiol 437, 85-93.
16. Weinlich M, Capasso G & Kinne RKH (1993). Intracellular pH in renal tubules in situ: Single-cell measurements by confocal laserscan microscopy. Pflügers Arch 422, 523-529.