Falcarinol is a covalent cannabinoid CB1 receptor antagonist and induces pro-allergic effects in skin

Biochemical Pharmacology

Volumn 79, Issue 12, 2010, Pages 1815-1826

  Leonti, Marco ^a   Casu, Laura ^a   Raduner, Stefan ^b   Cottiglia, Filippo ^a   Floris, Costantino ^a   Altmann, Karl Heinz ^b   Gertsch, Jürg ^b  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b ETH ZURICH   (Switzerland)

Author keywords

Anandamide; CB1 cannabinoid receptor; Endocannabinoid system; Falcarinol; Skin irritation

Indexed keywords

ANANDAMIDE; CANNABINOID 1 RECEPTOR; CANNABINOID 1 RECEPTOR ANTAGONIST; CANNABINOID 2 RECEPTOR; HISTAMINE; INTERLEUKIN 8; MONOCYTE CHEMOTACTIC PROTEIN 1; PANAXYNOL; RIMONABANT; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CHO CELL; CONTROLLED STUDY; DRUG EFFECT; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VIVO STUDY; KERATINOCYTE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRICK TEST; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKIN ALLERGY; SKIN EDEMA; SKIN INFLAMMATION;

ALLERGENS; ANIMALS; CELL LINE; CHEMOKINES; DERMATITIS, CONTACT; DIYNES; FATTY ALCOHOLS; HISTAMINE; HUMANS; KERATINOCYTES; RADIOLIGAND ASSAY; RECEPTOR, CANNABINOID, CB1;

EID: 77951297510     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.02.015     Document Type: Article

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