Identification of serotonin 5-HT1A receptor partial agonists in ginger

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 9, 2010, Pages 3345-3351

  Nievergelt, Andreas ^a   Huonker, Peter ^a   Schoop, Roland ^b   Altmann, Karl Heinz ^a   Gertsch, Jürg ^a  

^a ETH ZURICH   (Switzerland)

^b Bioforce AG   (Switzerland)

Author keywords

5 HT1A receptor; Anxiety; Caco 2; Ginger; Gingerol; Intestinal absorption; P glycoprotein; Serotonin; Shogaol

Indexed keywords

(10) GINGEROL; (6) GINGEROL; 1 DEHYDRO 6 GINGERDIONE; GINGER EXTRACT; GINGEROL; GLYCOPROTEIN P; GUANOSINE 5' O (3 THIOTRIPHOSPHATE); SEROTONIN 1A RECEPTOR; SHOGAOL; UNCLASSIFIED DRUG; VANILLOID RECEPTOR 1; VERAPAMIL; VINBLASTINE;

ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GINGER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; INTESTINE ABSORPTION; LIPOPHILICITY; PROTEIN TARGETING;

ANTI-ANXIETY AGENTS; CACO-2 CELLS; CATECHOLS; CELL LINE; FATTY ALCOHOLS; GINGER; HUMANS; MOLECULAR STRUCTURE; RECEPTOR, SEROTONIN, 5-HT1A;

ANIMALIA; ZINGIBER OFFICINALE;

EID: 77951294587     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.02.062     Document Type: Article

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