Turning the growth hormone receptor on: Evidence that hormone binding induces subunit rotation

Proteins: Structure, Function and Bioinformatics

Volumn 78, Issue 5, 2010, Pages 1163-1174

  Poger, David ^a   Mark, Alan E ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Cytokine receptor; Growth hormone; Molecular dynamics simulation; Receptor activation; Signal transduction

Indexed keywords

CYTOKINE; GROWTH HORMONE RECEPTOR; HUMAN GROWTH HORMONE; PROTEIN SUBUNIT;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; EXTRACELLULAR MATRIX; HORMONE BINDING; MUTAGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MOLECULAR DYNAMICS; MOLECULAR GENETICS; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CRYSTALLOGRAPHY, X-RAY; HUMAN GROWTH HORMONE; HUMANS; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; PROTEIN SUBUNITS; RECEPTORS, SOMATOTROPIN;

EID: 77951251864     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.22636     Document Type: Article

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