Inhibition of aldose reductase attenuates endotoxin signals in human non-pigmented ciliary epithelial cells

Experimental Eye Research

Volumn 90, Issue 5, 2010, Pages 555-563

  Yadav, Umesh C S ^a   Srivastava, Satish K ^a   Ramana, Kota V ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

Author keywords

Aldose reductase; HNPECs; Inflammation; LPS; Oxidative stress

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALDEHYDE REDUCTASE; CYCLOOXYGENASE 2; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRIC OXIDE; PROSTAGLANDIN E2; SORBINIL; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; ZOPOLRESTAT; ALKALINE PHOSPHATASE; BENZOTHIAZOLE DERIVATIVE; ENZYME INHIBITOR; IMIDAZOLIDINE DERIVATIVE; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE; NOS2A PROTEIN, HUMAN; PHTHALAZINE DERIVATIVE; PTGS2 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AQUEOUS HUMOR; ARTICLE; CELL STIMULATION; CILIARY BODY EPITHELIUM; CONTROLLED STUDY; CULTURE MEDIUM; DRUG MECHANISM; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; EYE INFLAMMATION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROSTAGLANDIN RELEASE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN INDUCTION; RAT; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CILIARY BODY; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; EPITHELIUM CELL; FLUORESCENT ANTIBODY TECHNIQUE; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; LEWIS RAT; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; WESTERN BLOTTING;

ALDEHYDE REDUCTASE; ALKALINE PHOSPHATASE; ANIMALS; BENZOTHIAZOLES; BLOTTING, WESTERN; CELLS, CULTURED; CILIARY BODY; CYCLOOXYGENASE 2; DINOPROSTONE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME INHIBITORS; EPITHELIAL CELLS; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HUMANS; IMIDAZOLIDINES; LIPOPOLYSACCHARIDES; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; OXIDATIVE STRESS; PHOSPHORYLATION; PHTHALAZINES; RATS; RATS, INBRED LEW; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSFECTION;

EID: 77951244866     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2010.01.012     Document Type: Article

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