SCOPUS 정보 검색 플랫폼

Volumn 21, Issue 6, 2010, Pages 661-663

Synthesis and antitumor evaluation of C3/C3 fluoroquinolone dimers (I): Tethered with a fused heterocyclic s-triazolo[2,1-b][1,3,4]thiadiazole

Author keywords

Antitumor evaluation; Dimer; Fluoroquinolone

Indexed keywords

EID: 77951216698 PISSN: 10018417 EISSN: None Source Type: Journal
DOI: 10.1016/j.cclet.2010.01.037 Document Type: Article

Times cited : (14)

References (8)

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8
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- 1a: yield 36, mp 245-247 °C. IR (KBr, υ, 3428, 3254, 2876, 1627, 1576, 1457, 1254 cm-1; 1H NMR (DMSO-d6, δ 10.64, 10.52 (brs, 2H, 2× HCl, 8.86-8.84 (br, 2H, 2× H-2, 7.62-7.57 (br, 2H, 2× H-8, 7.54-7.50 (br, 2H, 2× H-5, 3.82-3.72 (br, 2H, 2× CH-cyclopropyl, 3.36-2.68 (m, 16H, 2× piperazine-H, 2.42 (q, 2H, J, 7.2 Hz, N-CH2, 1.36-1.21 (m, 19H, CH3 and 4× CH2CH2-cyclopropyl, MS m/z: Found 725 (M++H, Calcd. 724.84 (M, Anal. Calcd. for C37H38F2N10O2S·2HCl: C 55.71, H 5.05, N 17.56; Found C 55.86, H 4.88, N 17.78. 1b: yield 42, mp 236-238 °C. IR (KBr, υ, 3445, 3227, 2926, 1624, 1566, 1455, 1278 cm-1; 1H NMR (DMSO-d6, δ 10.68, 10.57 (brs, 2H, 2× HCl, 8.86-8.82 (br, 2H, 2× H-2, 7.66-7.53 br, 2H, 2
- 2S ·2HCl: C 55.57, H 5.29, N 17.51; Found C 55.84, H 5.12, N 17.74.

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.