Effects of hyaluronan and iodine on wound contraction and granulation tissue formation in rat skin wounds: Clinical dermatology • Original article

Clinical and Experimental Dermatology

Volumn 35, Issue 4, 2010, Pages 373-379

  Slavkovsky, R ^a   Kohlerova, R ^b   Jiroutova, A ^b   Hajzlerova, M ^b   Sobotka, L ^c   Cermakova, E ^b   Kanta, J ^b  

^a CPN   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c Faculty Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYALURONIC ACID; HYIODINE; IODINE; UNCLASSIFIED DRUG; WOUND HEALING PROMOTING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DIABETES MELLITUS; DIGITAL IMAGING; DRUG MIXTURE; EPIDERMIS; EXCISION; GENE EXPRESSION; GRANULATION TISSUE; HISTOLOGY; MALE; MEDICAL PHOTOGRAPHY; MOLECULAR WEIGHT; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RAT; SKIN INJURY; WOUND CONTRACTION; WOUND FLUID; WOUND HEALING;

ANIMALS; CONTRACTURE; DRUG EVALUATION, PRECLINICAL; EPIDERMIS; EXUDATES AND TRANSUDATES; GENE EXPRESSION; GRANULATION TISSUE; HYALURONIC ACID; IODINE; MALE; PROTEINS; RATS; SKIN; URONIC ACIDS; WOUND HEALING;

EID: 77951214881     PISSN: 03076938     EISSN: 13652230     Source Type: Journal    
DOI: 10.1111/j.1365-2230.2009.03559.x     Document Type: Article

References (25)

1. Tammi MI, Day AJ, Turley EA. Hyaluronan and homeostasis: a balancing act. J Biol Chem 2002 277 : 4581 4584.
2. Chen WYJ, Abatangelo G. Functions of hyaluronan in wound repair. Wound Rep Reg 1999 7 : 79 89. (Pubitemid 29200045)
3. Balazs EA, Larsen NE. Hyaluronan: aiming for perfect skin regeneration. In : Scarless Wound Healing (Garg HG, Longaker MT, eds).
4. Karvinen S, Pasonen-Seppänen S, Hyttinen JMT et al. Keratinocyte growth factor stimulates migration and hyaluronan synthesis in the epidermis by activation of keratinocyte hyaluronan synthases 2 ad 3. J Biol Chem 2003 278 : 49495 49504.
5. Longaker MT, Chiu ES, Adzick NS et al. Studies in wound healing V. A prolonged presence of hyaluronic acid characterizes fetal wound fluid. Ann Surg 1991 213 : 292 296.
6. Noble PW. Hyaluronan and its catabolic products in tissue injury and repair. Matrix Biol 2002 21 : 25 9.
7. Richter AW, Ryde EM, Zetterstrom EO. Non-immunogenicity of a purified sodium hyaluronate preparation in man. Int Arch Allergy Appl Immunol 1979 59 : 45 8.
8. Arnold F, Jia C, He C et al. Hyaluronan, heterogeneity, and healing: the effects of ultrapure hyaluronan of defined molecular size on the repair of full-thickness pig skin wounds. Wound Rep Reg 1995 3 : 299 310.
9. Hu M, Sabelman EE, Cao Y et al. Three-dimensional hyaluronic acid grafts promote healing and reduce scar formation in skin incision wounds. J Biomed Mater Res Part B Appl Biomater 2003 67B : 586 592. (Pubitemid 37517111)
10. Abatangelo G, Martelli M, Vecchia P. Healing of hyaluronic acid-enriched wounds: histological observations. J Surg Res 1983 35 : 410 416. (Pubitemid 14234317)
11. Mack JA, Abramson SR, Ben Y et al. Hoxb13 knockout adult skin exhibits high levels of hyaluronan and enhanced wound healing. FASEB J 2003 17 : 1352 1354.
12. Selvaggi G, Monstrey S, Van Landuyt K et al. The role of iodine in antisepsis and wound management: a reappraisal. Acta Chir Belg 2003 103 : 241 247. (Pubitemid 38373205)
13. Vogt PM, Reimer K, Hauser J et al. PVP-iodine in hydrosomes and hydrogel - a novel concept in wound therapy leads to enhaced epithelialization and reduced loss of skin grafts. Burns 2006 32 : 698 705. (Pubitemid 44293057)
14. Ormiston MC, Seymour MTJ, Venn GE et al. Controlled trial of Iodosorb in chronic venous ulcers. Br Med J 1985 291 : 308 310. (Pubitemid 15045111)
15. Hunt T, Middelkoop E, eds. Iodine and Wound Physiology. A Symposium.
16. Sobotka L, Smahelova A, Pastorova J et al. A case report of the treatment of diabetic foot ulcers using a sodium hyaluronate and iodine complex. Int J Lower Extrem Wounds 2007 6 : 143 147. (Pubitemid 47301111)
17. Ajemian MS, Macaron S, Brenes R. Hyaluronate-iodine (hyiodine) complex in the treatment of non-healing wounds. J Am Coll Surg 2007 3 : S55.
18. Rudas B. Zur quantitativen Bestimmung von Granulationsgewebe in experimentell erzeugten Wunden. Arzneimittelforsch 1960 10 : 226 229.
19. Stegemann H. Mikrobestimmung von Hydroxyprolin mit Chloramin-T und p-dimethylaminobenzaldehyd. Hoppe-Seyler's Z Physiol Chem 1958 311 : 41 5.
20. Hurych J, Chvapil M. Methods of hydroxyproline determination (in Czech). Kozarstvi 1962 12 : 317 323.
21. 2+. J Invest Dermatol 2000 115 : 962 968. (Pubitemid 32037436)
22. Bitter T, Muir HM. A modified uronic acid carbazole reaction. Anal Biochem 1962 4 : 330 334.
23. Jiroutova A, Slavkovsky R, Cermakova M et al. Expression of mRNAs related to connective tissue metabolism in rat hepatic stellate cells and myofibroblasts. Exp Toxicol Pathol 2007 58 : 263 273. (Pubitemid 44873075)
24. Tammi R, Pasonen-Seppänen S, Kolehmainen E et al. Hyaluronan synthase induction and hyaluronan accumulation in mouse epidermis following skin injury. J Invest Dermatol 2005 124 : 898 905. (Pubitemid 40629088)
25. Vogt PM, Hauser J, Rossbach O et al. Polyvinylpyrrolidone-iodine liposome hydrogel improves epithelialization by combining moisture and antisepsis. A new concept in wound therapy. Wound Rep Reg 2001 9 : 116 122. (Pubitemid 32458318)