Overlapping in short motif sequences for binding to human REV7 and MAD2 proteins

Genes to Cells

Volumn 15, Issue 3, 2010, Pages 281-296

  Hanafusa, Tomo ^a   Habu, Toshiyuki ^a   Tomida, Junya ^a   Ohashi, Eiji ^a,c   Murakumo, Yoshiki ^b   Ohmori, Haruo ^a  

^a KYOTO UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

A DISINTEGRIN AND METALLOPROTEASE 9; CELL CYCLE PROTEIN 20; DNA POLYMERASE; PROTEIN MAD1; PROTEIN MAD2; PROTEIN REV7; TRANSCRIPTION FACTOR ELK 1; UNCLASSIFIED DRUG; ADAM PROTEIN; ADAM9 PROTEIN, HUMAN; DNA BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE; MAD2L2 PROTEIN, HUMAN; MEMBRANE PROTEIN; PROTEIN BINDING; REV3L PROTEIN, HUMAN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN ISOLATION; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; M PHASE CELL CYCLE CHECKPOINT; METABOLISM; PROTEIN DOMAIN;

ADAM PROTEINS; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; ETS-DOMAIN PROTEIN ELK-1; HUMANS; M PHASE CELL CYCLE CHECKPOINTS; MAD2 PROTEINS; MEMBRANE PROTEINS; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS;

EID: 77951175992     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2009.01380.x     Document Type: Article

References (39)

1. Cahill DP, da Costa LT, Carson-Walter EB, Kinzler KW, Vogelstein B, Lengauer C. Characterization of MAD2B and other mitotic spindle checkpoint genes. Genomics 1999, 58:181-187.
2. Chen J, Fang G. MAD2B is an inhibitor of the anaphase-promoting complex. Genes Dev. 2001, 15:1765-1770.
3. Cheung HW, Chun ACS, Wang Q, Deng W, Hu L, Guan X-Y, Nicholls JM, Ling M-T, Wong YC, Tsao SW, Jin D-Y, Wang X. Inactivation of human MAD2B in nasopharyngeal carcinoma cells leads to chemosensitization to DNA-damaging agents. Cancer Res. 2006, 66:4357-4367.
4. Choi JY, Guengerich FP. Kinetic analysis of translesion synthesis opposite bulky N2- and O6-alkylguanine DNA adducts by human DNA polymerase REV1. J. Biol. Chem. 2008, 283:23645-23655.
5. De Antoni A, Pearson CG, Cimini D, Canman JC, Sala V, Nezi L, Mapelli M, Sironi L, Faretta M, Salmon ED, Musacchio A. The Mad1/Mad2 complex as a template for Mad2 activation in the spindle assembly checkpoint. Curr. Biol. 2005, 15:214-225.
6. Gan GN, Wittschieben JP, Wittschieben Bthomampersand, Wood RD. DNA polymerase zeta (pol ζ) in higher eukaryotes. Cell Res. 2008, 18:174-183.
7. Gerlach VL, Feaver WJ, Fischhaber PL, Friedberg EC. Purification and characterization of pol κ, a DNA polymerase encoded by the human DINB1 gene. J. Biol. Chem. 2001, 276:92-98.
8. Iwai H, Kim M, Yoshikawa Y, Ashida H, Ogawa M, Fujita Y, Muller D, Kirikae T, Jackson PK, Kotani S, Sasakawa C. A bacterial effector targets Mad2L2, an APC inhibitor, to modulate host cell cycling. Cell 2007, 130:611-623.
9. Johnson RE, Prakash S, Prakash L. Efficient bypass of a thymine-thymine dimer by yeast DNA polymerase, Polη. Science 1999, 283:1001-1004.
10. Johnson RE, Prakash S, Prakash L. The human DINB1 gene encodes the DNA polymerase Pol θ. Proc. Natl Acad. Sci. USA 2000b, 97:3838-3843.
11. Johnson RE, Washington MT, Haracska L, Prakash S, Prakash L. Eukaryotic polymerases ι and ζ act sequentially to bypass DNA lesions. Nature 2000a, 406:1015-1019.
12. Lin W, Xin H, Zhang Y, Wu X, Yuan F, Wang Z. The human REV1 gene codes for a DNA template-dependent dCMP transferase. Nucleic Acids Res. 1999, 27:4468-4475.
13. Luo X, Tang Z, Rizo J, Yu H. The Mad2 spindle checkpoint protein undergoes similar major conformational changes upon binding to either Mad1 or Cdc20. Mol. Cell 2002, 9:59-71.
14. Mapelli M, Massimiliano L, Santaguida S, Musacchio A. The Mad2 conformational dimer: structure and implications for the spindle assembly checkpoint. Cell 2007, 131:730-743.
15. Mapelli M, Musacchio A. MAD contortions: conformational dimerization boosts spindle checkpoint signaling. Cur. Opin. Struct. Biol. 2007, 17:716-725.
16. Masutani C, Araki M, Yamada A, Kusumoto R, Nogimori T, Maekawa T, Iwai S, Hanaoka F. Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity. EMBO J. 1999a, 18:3491-3501.
17. Masutani C, Kusumoto R, Iwai S, Hanaoka F. Mechanisms of accurate translesion synthesis by human DNA polymerase η. EMBO J. 2000, 19:3100-3109.
18. Masutani C, Kusumoto R, Yamada A, Dohmae N, Yokoi M, Yuasa M, Araki M, Iwai S, Takio K, Hanaoka F. The XPV (Xeroderma pigmentosum variant) gene encodes human DNA polymerase η. Nature 1999b, 399:700-704.
19. Murakumo Y, Ogura Y, Ishii H, Numata S, Ichihara M, Croce CM, Fishel R, Takahashi M. Interactions in the error-prone postreplication repair proteins hREV1, hREV3, and hREV7. J. Biol. Chem. 2001, 276:35644-35651.
20. Murakumo Y, Roth T, Ishii H, Rasio D, Numata S, Croce CM, Fishel R. A human REV7 homolog that interacts with the polymerase ζ catalytic subunit hREV3 and the spindle assembly checkpoint protein hMAD2. J. Biol. Chem. 2000, 275:4391-4397.
21. Nelson JR, Gibbs PE, Nowicka AM, Hinkle DC, Lawrence CW. Evidence for a second function for Saccharomyces cerevisiae Rev1p. Mol. Microbiol. 2000, 37:549-554.
22. Nelson JR, Lawrence CW, Hinkle DC. Thymine-thymine dimer bypass by yeast DNA Polymerase ζ. Science 1996a, 272:1646-1649.
23. Nelson JR, Lawrence CW, Hinkle DC. Deoxycytidyl transferase activity of yeast REV1 protein. Nature 1996b, 382:729-731.
24. Nelson KK, Schlondorff J, Blobel CP. Evidence for an interaction of the metalloprotease-disintegrin tumor necrosis factor α convertase (TACE) with mitotic arrest deficient 2 (MAD2) and of the metalloprotease-disintegrin MDC9 with a novel MAD-related protein, MAD2β. Biochem. J. 1999, 343:673-680.
25. Ohashi E, Hanafusa T, Kamei K, Song I, Tomida J, Hashimoto H, Vaziri C, Ohmori H. Identification of a novel REV1-interacting motif necessary for DNA polymerase κ function. Genes Cells 2009, 14:101-111.
26. Ohashi E, Ogi T, Kusumoto R, Iwai S, Masutani C, Hanaoka F, Ohmori H. Error-prone bypass of certain DNA lesions by the human DNA polymerase κ. Genes Dev. 2000, 14:1589-1594.
27. Okada T, Sonoda E, Yoshimura M, Kawano Y, Saya H, Kohzaki M, Takeda S. Multiple roles of vertebrate REV genes in DNA repair and recombination. Mol. Cell. Biol. 2005, 25:6103-6111.
28. Pfleger CM, Salic A, Lee E, Kirschner MW. Inhibition of Cdh1-APC by the MAD2-related protein MAD2L2: a novel mechanism for regulating Cdh1. Genes Dev. 2001, 15:1759-1764.
29. Prakash S, Johnson RE, Prakash L. Eukaryotic translesion synthesis DNA polymerases: specificity of structure and function. Annu. Rev. Biochem. 2005, 74:317-353.
30. Rechkoblit O, Zhang Y, Guo D, Wang Z, Amin S, Krzeminsky J, Louneva N, Geacintov NE. Translesion synthesis past bulky benzo[a]pyrene diol epoxide N2-dG and N6-dA lesions catalyzed by DNA bypass polymerases. J. Biol. Chem. 2002, 277:30488-30494.
31. Sironi L, Mapelli M, Knapp S, De Antoni A, Jeang KT, Musacchio A. Crystal structure of the tetrameric Mad1-Mad2 core complex: implications of a 'safety belt' binding mechanism for the spindle checkpoint. EMBO J. 2002, 21:2496-2506.
32. Suzuki N, Ohashi E, Kolbanovskiy A, Geacintov NE, Grollman AP, Ohmori H, Shibutani S. Translesion synthesis by human DNA polymerase κ on a DNA template containing a single stereoisomer of dG-(+)- or dG-(-)-anti-N2-BPDE (7,8-dihydroxy-anti-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene). Biochemistry 2002, 41:6100-6106.
33. Tissier A, Frank EG, McDonald JP, Iwai S, Hanaoka F, Woodgate R. Misinsertion and bypass of thymine-thymine dimers by human DNA polymerase ι. EMBO J. 2000, 19:5259-5266.
34. Weterman MA, van Groningen JJM, Tertoolen L, van Kessel AG. Impairment of MAD2B-PRCC interaction in mitotic checkpoint defective t(X;1) positive renal cell carcinoma. Proc. Natl Acad. Sci. USA 2001, 98:13808-13813.
35. Yang M, Li B, Tomchick DR, Machius M, Rizo J, Yu H, Luo X. p31comet blocks Mad2 activation through structural mimicry. Cell 2007, 131:744-755.
36. Yang W, Woodgate R. What a difference a decade makes: insights into translesion DNA synthesis. Proc. Natl Acad. Sci. USA 2007, 104:15591-15598.
37. Yu H. Structural activation of Mad2 in the mitotic spindle checkpoint: the two-state Mad2 model versus the Mad2 template model. J. Cell Biol. 2006, 173:153-157.
38. Zhang L, Yang S-H, Sharrocks AD. Rev7/MAD2B links c-Jun N-terminal protein kinase pathway signaling to activation of the transcription factor Elk-1. Mol. Cell. Biol. 2007, 27:2861-2869.
39. Zhang Y, Yuan F, Wu X, Wang M, Rechkoblit O, Taylor JS, Geacintov NE, Wang Z. Error-free and error-prone lesion bypass by human DNA polymerase κ in vitro. Nucleic Acids Res. 2000, 28:4138-4146.