Establishing a model spinal cord injury in the African green monkey for the preclinical evaluation of biodegradable polymer scaffolds seeded with human neural stem cells

Journal of Neuroscience Methods

Volumn 188, Issue 2, 2010, Pages 258-269

  Pritchard, Christopher D ^a,c   Slotkin, Jonathan R ^b   Yu, Dou ^c   Dai, Haining ^d   Lawrence, Matthew S ^e   Bronson, Roderick T ^f   Reynolds, Francis M ^g   Teng, Yang D ^c   Woodard, Eric J ^h   Langer, Robert S ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

^b Washington Brain and Spine Institute   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

^e RxGen Inc   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

^g InVivo Therapeutics Corporation   (United States)

^h NEW ENGLAND BAPTIST HOSPITAL   (United States)

Author keywords

African green monkey; Behavioral scoring; Biomaterials; Injury model; Non human primate; Spinal cord injury; Stem cells

Indexed keywords

POLYGLACTIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADABLE IMPLANT; BLADDER FUNCTION; BROWN SEQUARD SYNDROME; CERCOPITHECIDAE; CLINICAL EVALUATION; COGNITION; CONTROLLED STUDY; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HYPESTHESIA; IMMUNOHISTOCHEMISTRY; INJURY SEVERITY; INTESTINE FUNCTION; LIMB DISEASE; MACROPHAGE ACTIVATION; MALE; MICROGLIA; NEURAL STEM CELL; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; OUTCOME ASSESSMENT; PARALYSIS; PRIORITY JOURNAL; SPINAL CORD HEMISECTION; SPINAL CORD INJURY; THORACIC SPINE; TREATMENT RESPONSE;

ABSORBABLE IMPLANTS; ANIMALS; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; DISEASE MODELS, ANIMAL; GRAFT SURVIVAL; HUMANS; MALE; NEUROGENESIS; NEURONS; NEUROSURGICAL PROCEDURES; PROSTHESIS IMPLANTATION; RECOVERY OF FUNCTION; SPINAL CORD INJURIES; STEM CELL TRANSPLANTATION; STEM CELLS; TISSUE SCAFFOLDS; TREATMENT OUTCOME;

EID: 77951175537     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2010.02.019     Document Type: Article

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