Poly(vinyl alcohol) films for topical delivery of S-nitrosoglutathione: Effect of freezing-thawing on the diffusion properties

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 93, Issue 2, 2010, Pages 416-424

  De Souza Godoy Simões, Maíra Martins ^a   De Oliveira, Marcelo Ganzarolli ^a  

^a UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Diffusion; Freezing thawing; Nitric oxide; Poly(vinyl alcohol); S nitrosoglutathione; Vasodilation

Indexed keywords

BASAL LEVELS; BIOCOMPATIBLE POLYMER; BLOOD FLOW; CRYSTALLINITIES; DIFFUSION COEFFICIENTS; DIFFUSION PROPERTIES; FREEZING THAWING CYCLES; FREEZING-THAWING; IN-VITRO; ISCHEMIC TISSUES; LASER DOPPLER FLOWMETRY; MACROPORES; PHARMACEUTICAL PRODUCTS; PVA FILMS; RADIUS OF GYRATION; S-NITROSOGLUTATHIONE; TISSUE PERFUSION; TOPICAL DELIVERY; WOUND DRESSINGS;

BLOOD; DIFFUSION; FREEZING; HEMODYNAMICS; NITRIC OXIDE; RESPIRATORY MECHANICS; THAWING;

FILMS;

POLYVINYL ALCOHOL; S NITROSOGLUTATHIONE;

ADULT; ARTICLE; BLOOD FLOW; CONTROLLED STUDY; CRYSTALLIZATION; DERMIS; DIFFUSION COEFFICIENT; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; FEMALE; FILM; FREEZE THAWING; HUMAN; IN VITRO STUDY; ISCHEMIA; LASER DOPPLER FLOWMETRY; MALE; NORMAL HUMAN; SKIN; TISSUE PERFUSION; VASODILATATION; WOUND DRESSING;

ADMINISTRATION, TOPICAL; ADULT; BIOCOMPATIBLE MATERIALS; BLOOD FLOW VELOCITY; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; ISCHEMIA; MALE; MEMBRANES, ARTIFICIAL; POLYVINYL ALCOHOL; POROSITY; S-NITROSOGLUTATHIONE; SKIN; VASODILATION; VASODILATOR AGENTS;

EID: 77951174873     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.31598     Document Type: Article

References (42)

1. Veves A, Akbari CM, Primavera J, Donaghue VM, Zacharoulis D, Chrzan JS, DeGirolami U, LoGerfo FW, Freeman R. Endothelial dysfunction and the expression of endothelial nitric oxide synthetase in diabetic neuropathy, vascular disease, and foot ulceration. Diabetes 1998;47:457-463. (Pubitemid 28104210)
2. Dinh T, Veves A. Microcirculation of the diabetic foot. Curr Pharm Des 2005;11:2301-2309.
3. Herrick AL. Pathogenesis of Raynaud's phenomenon. Rheumatology 2005;44:587-596.
4. Greenman RL, Panasyuk S, Wang X, Lyons TE, Dinh T, Longoria L, Giurini JM, Freeman J, Khaodhiar L, Veves A. Early changes in the skin microcirculation and muscle metabolism of the diabetic foot. Lancet 2005;366:1711-1717. (Pubitemid 41587450)
5. Higashi Y, Noma K, Yoshizumi M, Kihara Y. Endothelial function and oxidative stress in cardiovascular diseases. Circ J 2009;73:411-418.
6. Schafer A, Bauersachs J. Endothelial dysfunction, impaired endogenous platelet inhibition and platelet activation in diabetes and atherosclerosis. Curr Vasc Pharmacol 2008;6:52-60.
7. Ignarro LJ, Napoli C, Loscalzo J. Nitric oxide donors and cardiovascular agents modulating the bioactivity of nitric oxide - An overview. Circ Res 2002;90:21-28. (Pubitemid 34074604)
8. Gerova M, Kristek F. Efficiency of NO donors in substituting impaired endogenous NO production: A functional and morphological study. Physiol Res 2001;50:165-173. (Pubitemid 32523438)
9. Seabra AB, Fitzpatrick A, Paul J, De Oliveira MG, Weller R. Topically applied S-nitrosothiol-containing hydrogels as experimental and pharmacological nitric oxide donors in human skin. Br J Dermatol 2004;151:977-983. (Pubitemid 39573885)
10. Seabra AB, Pankotai E, Feher M, Somlai A, Kiss L, Biro L, Szabo C, Kollai M, de Oliveira MG, Lacza Z. S-nitrosoglutathione-containing hydrogel increases dermal blood flow in streptozotocininduced diabetic rats. Br J Dermatol 2007;156:814-818. (Pubitemid 46642806)
11. Kabanov AV, Batrakova EV, Alakhov VY Pluronic (R) block copolymers as novel polymer therapeutics for drug and gene delivery. J Control Release 2002;82:189-212. (Pubitemid 34880178)
12. Lozinsky VI, Plieva FM Poly(vinyl alcohol) cryogels employed as matrices for cell immobilization. Overview of recent research developments. Enzyme Microb Technol 1998;23:227-243.
13. El-Hameed MD, Kellaway IW. Preparation and in vitro carachterization of mucoadhesive polymeric microspheres as intra-nasal delivery systems. Eur J Pharm Biopharm 1997;44:53-60.
14. Winterton LC, Lally JM, Sentell KB, Chapoy LL. The elution of Poly(vinyl alcohol) from contact lens: The realization of a time moisturizing agent/artificial tear. J Biomed Mater Res B Appl Biomater 2007;80(B):424-432. (Pubitemid 46245594)
15. Hyon SH, Cha WI, Ikada Y, Kita M, Ogura Y, Honda Y. Poly(vinyl alcohol) hydrogels as soft contact-lens material. J Biomater Sci Polym Ed 1994;5:397-406. (Pubitemid 20214017)
16. Lee SG, Kim JP, Lyoo WS, Kwak JW, Noh SK, Park CS, Kim JH. Preparation of novel syndiotatic poly(vinyl alcohol) microspheres through the low-temperature suspension copolymerization of vinyl pivalate and vinyl acetate and heterogeneous saponification. J Appl Polym Sci 2005;95:1539-1548.
17. Tamura K, Nakamura T, Ike O, Hitomi S, Shimizu Y, Mambu M, Teramatsu T. New hydrogel from PVA and its fundamental study for medical application - Changes of properties after implantation and application as non-adhesive membrane for intestines. Artif Organs 1988;12:462. (Pubitemid 16165012)
18. Masters KSB, Leibovich SJ, Belem P, West JL, Poole-Warren LA. Effects of nitric oxide releasing poly(vinyl alcohol) hydrogel dressings on dermal wound healing in diabetic mice. Wound Repair Regen 2002;10:286-294. (Pubitemid 35315676)
19. Young TH, Chuang WY, Yao NK, Chen LW. Use of a diffusion model for assessing the performance of poly(vinyl alcohol) bioartificial pancreases. J Biomed Mater Res A 1998;40:385-392.
20. Wan WK, G C, Zhang ZF, Hui AJ, Boughner DR. Optimizing the tensile properties of poly(vinyl alcohol) hydrogel for the construction of a bioprosthetic heart valve stent. J Biomed Mater Res A 2002;63:854-861.
21. Cascone MG, Sim B, Downes S. Blends of synthetic and natural polymers as drug delivery systems for growth hormone. Biomaterials 1995;16:569-574.
22. Brieger D, Topol E. Local drug delivery systems and prevention of restenosis. Cardiovasc Res 1997;35:405-413. (Pubitemid 27469401)
23. Peppas NA, editor. Polymer, Vol. 2. Boca Raton: CRC; 1987. 1-48 p.
24. Horiike S, Matsuzawa S, Yamaura K. Preparation of chemically crosslinked gels with maleate-denatured poly(vinyl alcohol) and its application to drug release. J Appl Polym Sci 2002;84:1178-1184. (Pubitemid 34239574)
25. Peppas NA, Bures P, Leobandung W, Ichikawa H. Hydrogels in pharmaceutical formulations. Eur J Pharm Biopharm 2000;50:37-56.
26. Seabra AB, de Oliveira MG. Poly(vinyl alcohol) and poly(vinyl pyrrolidone) blended films for local nitric oxide release. Biomaterials 2004;25:3773-3782.
27. Stauffer SR, Peppas NA. Poly(vinyl alcohol) hydrogels prepared by freezing and thawing cyclic processing. Polymer 1992;33:3932-3936.
28. Hassan CM, Peppas NA. Structure and applications of poly(vinyl alcohol) hydrogels produced by conventional crosslinking or by freezing/thawing methods. Adv Polym Sci 2000;153:37-65.
29. Hassan CM, Peppas NA. Structure and morphology of freeze/thawed PVA hydrogels. Macromolecules 2000;33:2472-2479.
30. El Fray M, Pilaszkiewicsz A, Swieszkowiski W, Kurzydlowiski KJ. Morphology assessment f chemically modified and cryostructured poly(vinyl alcohol) hydrogel. Eur Polym J 2007;43:2035-2040. (Pubitemid 46660864)
31. Gutierrez MC, Garcia-Carvajal ZY, Jobbagy M, Rubio T, Yuste L, Rojo F, Ferrer ML, del Monte F. Poly(vinyl alcohol) scaffolds with tailored morphologies for drug delivery and controlled release. Adv Funct Mater 2007;17:3505-3513. (Pubitemid 350221703)
32. Hickey AS, Peppas NA. Mesh size and diffusive characteristics of semicrystalline poly (vinyl alcohol) membranes prepared by freezing-thawing techniques. J Memb Sci 1995;107:229-237.
33. Ricciardi R, Auriemma F, Gaillet C, De Rosa C, Laupretre F. Investigation of the crystallinity of freeze/thaw poly(vinyl alcohol) hydrogels by different techniques. Macromolecules 2004;37:9510-9516. (Pubitemid 40002678)
34. Mandelkern L, Alamo R. Physical Properties of Polymers Handbook. New York: Springer Science + Business Media; 2007. 165-169 p.
35. Willcox PJ, Howie DW, Schmidt-Rohr K, Hoagland DA, Gido SP, Pudjijanto S, Kleiner LW, Venkatraman S. Microstructure of poly (vinyl alcohol) hydrogels produced by freeze/thaw cycling. J Polym Sci B Polym Phys 1999;37:3438-3454. (Pubitemid 32261987)
36. Franz TJ. Percutaneous absorption - Relevance of in vitro data. J Invest Dermatol 1975;64:190-195.
37. Wagner JG. Interpretation of percent dissolved-time plots derived from in vitro testing of conventional tablets and capsules. J Pharm Sci 1969;58:1253.
38. Miyazaki T, Hoshiko A, Akasaka M, Shintani T, Sakurai S. SAXS studies on structural changes in a poly(vinyl alcohol) film during uniaxial stretching in water. Macromolecules 2006;39:2921-2929.
39. Hatakeyema T, Uno J, Yamada C, Kishi A, Hatakeyama H. Gel-sol transition of poly(vinyl alcohol) hydrogels formed by freezing and thawing. Thermochim Acta 2005;431:144-148. (Pubitemid 40773905)
40. Ricciardi R, Mangiapia G, Lo Celso F, Paduano L, Triolo R, Auriemma F, De Rosa C, Laupretre F. Structural organization of poly(vinyl alcohol) hydrogels obtained by freezing and thawing techniques: A SANS study. Chem Mater 2005;17:1183-1189. (Pubitemid 40344043)
41. Amadeu TP, Seabra AB, de Oliveira MG, Costa AMA. S-nitrosoglutathione- containing hydrogel accelerates rat cutaneous wound repair. J Eur Acad Dermatol Venereol 2007;21:629-637.
42. Amadeu TP, Seabra AB, de Oliveira MG, Monte-Alto-Costa A. Nitric oxide donor improves healing if applied on inflammatory and proliferative phase. J Surg Res 2008;149:84-93.