Bone repair by cell-seeded 3D-bioplotted composite scaffolds made of collagen treated tricalciumphosphate or tricalciumphosphate-chitosan-collagen hydrogel or PLGA in ovine critical-sized calvarial defects

Journal of Biomedical Materials Research - Part B Applied Biomaterials

Volumn 93, Issue 2, 2010, Pages 520-530

  Haberstroh, Kathrin ^a   Ritter, Kathrin ^b   Kuschnierz, Jens ^b   Bormann, Kai Hendrik ^c   Kaps, Christian ^a   Carvalho, Carlos ^d   Mülhaupt, Rolf ^d   Sittinger, Michael ^a   Gellrich, Nils Claudius ^c  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b UNIVERSITY OF FREIBURG   (Germany)

^c LEIBNIZ UNIVERSITY HANNOVER   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BONE REPAIR; CALVARIAL DEFECTS; CELL-FREE; COMPLEX STRUCTURE; COMPOSITE SCAFFOLDS; DEFECT HEALING; DEFECT MODEL; GLYCOLIDE; L-LACTIDE; MANUFACTURING PROCESS; MATERIAL COMPOSITIONS; OSTEOBLAST-LIKE CELLS; OSTEOGENIC EFFECTS; OSTEOINDUCTIVE PROPERTIES; PERIOST; RANDOMIZED DESIGN; RELATIVE DENSITY;

ANIMALS; BIODEGRADATION; BIOMATERIALS; BONE; CHITIN; CHITOSAN; COLLAGEN; DEFECTS; DEGRADATION; HYDROGELS; MICROBIOLOGY; ORGANIC POLYMERS; STIFFNESS; SURGERY; THREE DIMENSIONAL;

SCAFFOLDS;

CALCIUM PHOSPHATE; CHITOSAN; COLLAGEN; POLYGLACTIN; TISSUE SCAFFOLD;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIODEGRADATION; BONE REMODELING; CALVARIA; CONTROLLED STUDY; CRANIOFACIAL SURGERY; DENSITY; EUTHANASIA; FEMALE; FRACTURE HEALING; HYDROGEL; MORPHOMETRICS; NONHUMAN; OSSIFICATION; OSTEOBLAST; OSTEOTOMY; PERIOSTEUM; PROSPECTIVE STUDY; RIGIDITY; SHEEP; SKULL DEFECT;

ABSORBABLE IMPLANTS; ANIMALS; BONE REGENERATION; CALCIUM PHOSPHATES; CHITOSAN; COLLAGEN; DISEASE MODELS, ANIMAL; FEMALE; GLYCOLATES; HYDROGELS; SHEEP; SKULL; TIME FACTORS; TISSUE SCAFFOLDS;

EID: 77951170997     PISSN: 15524973     EISSN: 15524981     Source Type: Journal    
DOI: 10.1002/jbm.b.31611     Document Type: Article

References (39)

1. Itthichaisri C, Wiedmann-Al-Ahmad M, Huebner U, Al-Ahmad A, Schoen R, Schmelzeisen R. Comparative in vitro study of the proliferation and growth of human osteoblast-like cells on various biomaterials. J Biomed Mater Res A 2007;82:777-787. (Pubitemid 47312893)
2. Vacanti JP. Beyond transplantation. Third annual Samuel Jason Mixter lecture. Arch Surg 1988;123:545-549.
3. Quarto R, Mastrogiacomo M, Cancedda R, Kutepov SM, Mukhachev V, Lavroukov A. Repair of large bone defects with the use of autologous bone marrow stromal cells. N Engl J Med 2001;344:385-386. (Pubitemid 32107654)
4. Hutmacher D, Cool S. Concepts of scaffold-based tissue engineering: The rationale to use solid free-form fabrication techniques. J Cell Mol Med 2007;11:654-669. (Pubitemid 47315712)
5. Govender S, Csimma C, Genant HK, Valentin-Opran A, Amit Y, Arbel R, Aro H, Atar D, Bishay M, Börner MG, Chiron P, Choong P, Cinats J, Courtenay B, Feibel R, Geulette B, Gravel C, Haas N, Raschke M, Hammacher E, van der Velde D, Hardy P, Holt M, Josten C, Ketterl RL, Lindeque B, Lob G, Mathevon H, McCoy G, Marsh D, Miller R, Munting E, Oevre S, Nordsletten L, Patel A, Pohl A, Rennie W, Reynders P, Rommens PM, Rondia J, Rossouw WC, Daneel PJ, Ruff S, Rüter A, Santavirta S, Schildhauer TA, Gekle C, Schnettler R, Segal D, Seiler H, Snowdowne RB, Stapert J, Taglang C, Verdonk R, Vogels L, Weckbach A, Wentzensen A, Wisniewski T. Recombinant human bone morphogenetic protein-2 for treatment of open tibial fractures: A prospective, controlled, randomized study of four hundred and fifty patients. J Bone Joint Surg Am 2002;84A:2123-2134. (Pubitemid 35417689)
6. Liebermann I, Togawa D, Kayanja M. Vertebroplasty and kyphoplasty: Filler materials. Spine J 2005;5:305S-316S.
7. Karageorgiou V, Kaplan D. Porosity of 3D biomaterial scaffolds and osteogenesis. Biomaterials 2005;26:5474-5491.
8. Landers R, Mülhaupt R. Desktop manufacturing of complex objects, prototypes and biomedical scaffolds by means of computer-assisted design combined with computer-guided 3D plotting of polymers and reactive oligomers. Macromol Mater Eng 2000;282:17-21.
9. Lu L, Mikos A. The importance of new processing techniques in tissue engineering. MRS Bull 1996;21:28-32. (Pubitemid 126562406)
10. Hutmacher D. Scaffolds in tissue engineering bone and cartilage. Biomaterials 2000;21:2529-2543.
11. Leong K, Cheah C, Chua C. Solid freeform fabrication of three-dimensional scaffolds for engineering replacement tissues and organs. Biomaterials 2003;24:2363-2378. (Pubitemid 36434056)
12. O'Brian FJ, Harley BA, Waller MA, Yannas IV, Gibson LJ, Prendergast PJ. The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering. Technol Health Care 2007;15:3-17.
13. Landers R, Hübner U, Schmelzeisen R, Mülhaupt R. Rapid prototyping of scaffolds derived from thermoreversible hydrogels and tailored for applications in tissue engineering. Biomaterials 2002;23:437-4447. (Pubitemid 36151595)
14. Jansen EJ, Sladek RE, Bahar H, Yaffe A, Gijbels MJ, Kuijer R, Bulstra SK, Guldemond NA, Binderman I, Koole LH. Hydrophobicity as a design criterion for polymer scaffolds in bone tissue engineering. Biomaterials 2005;26:4423-4431. (Pubitemid 40208603)
15. Zheng YX, Ringe J, Liang Z, Loch A, Chen L, Sittinger M. Osteogenic potential of human periosteum-derived progenitor cells in PLGA scaffold using allogeneic serum. J Zhejiang Univ Sci B 2006;7:817-824.
16. Arnsdorf EJ, Jones LM, Carter DR, Jacobs CR. The periosteum as a cellular source for functional tissue engineering. Tissue Eng Part A 2009;15:2637-2642.
17. Hutmacher DW, Sittinger M. Periosteal cells in bone tissue engineering. Tissue Eng 2003;9:45-64.
18. Wiedmann-Al-Ahmad M, Gutwald R, Lauer G, Hübner U, Schmelzeisen R. How to optimize seeding and culturing of human osteoblast-like cells on various biomaterials. Biomaterials 2002;23:3319-3328. (Pubitemid 34615639)
19. Wissing H, Stürmer K, Breidenstein G. Die Wertigkeit verschiedener Versuchsspezies für experimentelle Untersuchungen am Knochen. Hefte Unfallheilkd 1990;212:479-488.
20. Rehmann I, Smith R, Hench L, Bonfield W. Structural evaluation of human and sheep bone and comparison with synthetic hydroxyapatite by FT-Raman spectroscopy. J Biomed Mater Res 1995;29:1287-1294.
21. Schenk RK, Olah AJ, Herrmann P. Preparation of calcified tissues for light microscopy. In: Dickson GR, editor. Methods of Calcified Tissue Preparation. Amsterdam: Elsevier; 1984. pp 1-56.
22. Richardson KC, Jarrett L, Finke EH. Embedding in epoxy resins for ultrathin sectioning in electron microscopy. Stain Technology 1960;35:313.
23. Laczko J, Levai G. A simple differential staining method for semithin sections of ossifying cartilage and bone tissues embedded in epoxy resin. Mikroskopie 1975;31:1-4.
24. Göpferich A. Mechanisms of polymer degradation and erosion. Biomaterials 1996;17:103-114.
25. Sung HJ, Meredith C, Johnson C, Galis ZS. The effect of scaffold degradation rate on three-dimensional cell growth and angiogenesis. Biomaterials 2004;25:5735-5742. (Pubitemid 38624453)
26. Agrawal CM, Ray RB. Biodegradable polymeric scaffolds for musculoskeletal tissue engineering. J Biomed Mater Res 2001;55:141-150. (Pubitemid 32198496)
27. Rücker M, Laschke M, Junker D, Carvalho C, Schramm A, Mülhaupt R, Gellrich NC, Menger MD. Angiogenic and inflammatory response to biodegradable scaffolds in dorsal skinfold chambers of mice. Biomaterials 2006;27:5027-5038. (Pubitemid 43949420)
28. Munar ML, Udoh K, Ishikawa K, Matsuya S, Nakagawa M. Effects of sintering temperature over 1,300 degrees C on physical and compositional properties of porous hydroxyapatite foam. Dent Mater J 2006;25:51-58. (Pubitemid 44228797)
29. Lin JH, Kuo KH, Ding SJ, Ju CP. Surface reaction of stoichiometric and calcium-deficient hydroxyapatite in simulated body fluid. J Sci Mater Med 2001;12:731-741. (Pubitemid 32826385)
30. Lahiji A, Schrabi A, Hungerford DS, Frondoza CG. Chitosan supports the expression of extracellular matrix proteins in human osteoblasts and chondrocates. J Biomed Mater Res 2005;51:586-595. (Pubitemid 30450717)
31. Di Martino A, Sittinger M, Risbud MV. Chitosan: A versatile biopolymer for orthopedic tissue-engineering. Biomaterials 2005;26:5983-5990. (Pubitemid 40805604)
32. Zhao F, Grayson WL, Ma T, Bunnell B, Lu WW. Effects of hydroxyapatite in 3D chitosan-gelatin polymer network on human mesenchymal stem cell construct development. Biomaterials 2006;27:1859-1867. (Pubitemid 41759480)
33. Sivakumar M, Manjubala I, Rao K. Preparation, characterization and in vitro release of gentamicin from corraline hydroxyapatite-chitosan composite microspheres. Carbohydr Polym 2002;49:281-288. (Pubitemid 34466724)
34. Suh JK, Matthew HU. Application of chitosan based polysaccharide biomaterials in cartilage tissue engineering: A review. Biomaterials 2000;21:2589-2598.
35. Manjubala I, Woesz A, Pilz C, Rumpler M, Fratzl-Zelman N, Roschger P, Stampfl J, Fratzl P. Biomimetic mineral-organic composite scaffolds with controlled internal architecture. J Mater Sci Mater Med 2005;16:1111-1119. (Pubitemid 41803735)
36. Lee YM, Park YJ, Lee SJ, Ku Y, Han SB, Choi SM, Klokkevold PR, Chung CP. Tissue engineered bone formation using chitosan/tricalcium phosphate sponges. J Periodontal 2000;71:410-417.
37. Giunchedi P, Genta I, Conti B, Muzzarelli R, Conti U. Preparation and characterization of ampicillin loaded methylpyrrolidie chitosan and chitosan microspheres. Biomaterials 1998;19:157-161. (Pubitemid 28239479)
38. Bumgardner JD, Wiser R, Gerard PD, Bergin P, Chestnutt B, Marin M, Ramsey V, Elder SH, Gilbert JA. Chitosan: Potential use as a bioactive coating for orthopedic and craniofacial/dental implants. J Biomater Sci Polym Ed 2003;14:423-438. (Pubitemid 36681493)
39. Qu X, Cui W, Yang F, Min C, Shen H, Bei J, Wang S. The effect of oxygen plasma pretreatment and incubation in modified simulated body fluids on the formation of bone-like apatite on poly(-lactide-co-glycolide)(70/30). Biomaterials 2007;28:9-18. (Pubitemid 44427900)