Direct, one-pot sequential reductive alkylation of lactams/amides with grignard and Organolithium reagents through lactam/amide activation

Angewandte Chemie - International Edition

Volumn 49, Issue 17, 2010, Pages 3037-3040

  Xiao, Kai Jiong ^a   Luo, Jie Min ^a   Ye, Ke Yin ^a   Wang, Yu ^a   Huang, Pei Qiang ^a  

^a XIAMEN UNIVERSITY   (China)

Author keywords

Amides; Multicomponent reactions; Sequential reductive alkylation; Synthetic methods; Teri alkylamines

Indexed keywords

ALKYL AMINES; MULTI-COMPONENT REACTIONS; REDUCTIVE ALKYLATION; SYNTHETIC METHODS; TERI-ALKYLAMINES;

ALKYLATION; HYDROCARBONS;

AMIDES;

AMIDE; AMINE; LACTAM; LITHIUM DERIVATIVE;

ALKYLATION; ARTICLE; CHEMISTRY; COMBINATORIAL CHEMISTRY; METHODOLOGY; OXIDATION REDUCTION REACTION; SYNTHESIS;

ALKYLATION; AMIDES; AMINES; COMBINATORIAL CHEMISTRY TECHNIQUES; LACTAMS; LITHIUM COMPOUNDS; OXIDATION-REDUCTION;

EID: 77951147307     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201000652     Document Type: Article

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