Focus on Molecules: Platelet-derived growth factor C, PDGF-C

Experimental Eye Research

Volumn 86, Issue 5, 2008, Pages 711-712

  Lei, Hetian ^a   Kazlauskas, Andrius ^a  

^a SCHEPENS EYE RESEARCH INSTITUTE   (United States)

Author keywords

angiogenesis; fibrosis; PDGF C; plasmin; proliferative vitreoretinopathy; tPA

Indexed keywords

PLASMIN; PLATELET DERIVED GROWTH FACTOR C; PLATELET DERIVED GROWTH FACTOR RECEPTOR; TISSUE PLASMINOGEN ACTIVATOR;

ANGIOGENESIS; CARCINOGENESIS; DIABETIC RETINOPATHY; FIBROSIS; MOLECULE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; RETROLENTAL FIBROPLASIA; SHORT SURVEY;

ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; EYE DISEASES; HUMANS; LYMPHOKINES; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; PLATELET-DERIVED GROWTH FACTOR;

EID: 42949130075     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.exer.2007.08.007     Document Type: Short Survey

References (4)

1. Fredriksson L., Li H., and Eriksson U. The PDGF family: four gene products form five dimeric isoforms. Cytokine Growth Factor Rev. 15 (2004) 197-204
2. Lei, H., Velez, G., Hovland, P., Hirose, T., Kazlauskas, A., 2007a. Plasmin is the major protease responsible for processing PDGF-C in the vitreous of patients with proliferative vitreoretinopathy, submitted for publication.
3. Lei H., Hovland P., Velez G., Haran A., Gilbertson D., Hirose T., and Kazlauskas A. A potential role for PDGF-C in experimental and clinical proliferative vitreoretinopathy. Investig. Ophthalmol. Vis. Sci. 48 (2007) 2335-2342
4. Reigstad L.J., Varhaug J.E., and Lillehaug J.R. Structural and functional specificities of PDGF-C and PDGF-D, the novel members of the platelet-derived growth factors family. FEBS J. 272 (2005) 5723-5741