Imatinib buys time for brain after stroke

Nature Medicine

Volumn 14, Issue 7, 2008, Pages 712-713

  Rieckmann, Peter ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

IMATINIB; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR C; TISSUE PLASMINOGEN ACTIVATOR;

ASTROCYTE; BLOOD BRAIN BARRIER; BLOOD CLOT LYSIS; BRAIN HEMORRHAGE; CEREBROVASCULAR ACCIDENT; DRUG MEGADOSE; HUMAN; MEMBRANE PERMEABILITY; MIDDLE CEREBRAL ARTERY OCCLUSION; NERVE DEGENERATION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SEIZURE; SHORT SURVEY; SINGLE DRUG DOSE; STROKE;

ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; BRAIN ISCHEMIA; CEREBRAL ARTERIES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LYMPHOKINES; MICE; MODELS, BIOLOGICAL; PIPERAZINES; PLATELET-DERIVED GROWTH FACTOR; PYRIMIDINES; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; SIGNAL TRANSDUCTION; STROKE; TIME FACTORS;

EID: 46749142936     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm0708-712     Document Type: Short Survey

References (13)

1. de la Ossa, N.P. et al. Neurology 70, 1238-1243 (2008).
2. Kulkens, S. & Hacke, W. Expert Rev. Neurother. 7, 783-788 (2007).
3. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N. Engl. J. Med. 333, 1581-1587 (1995).
4. Tsirka, S.E. et al. J. Neurosci. 17, 543-552 (1997).
5. Wang, Y.F. et al. Nat. Med. 4, 228-231 (1998).
6. Zhuo, M. et al. J. Neurosci. 20, 542-549 (2000).
7. Su, E.J. et al. Nat. Med. 14, 731-737 (2008).
8. Fredriksson, L., Li, H., Fieber, C., Li, X. & Eriksson, U. EMBO J. 23, 3793-3802 (2004).
9. Yepes, M. et al. J. Clin. Invest. 112, 1533-1540 (2003).
10. Nicole, O. et al. Nat. Med. 7, 59-64 (2001).
11. Breedveld, P., Beijnen, J.H. & Schellens, J.H. Trends Pharmacol. Sci. 27, 17-24 (2006).
12. Krupinski, J. et al. Stroke 28, 564-573 (1997).
13. Endres, M. et al. Cerebrovasc. Dis. 25, 268-278 (2008).