Cerebral Salt Wasting: Pathophysiology, Diagnosis, and Treatment

Neurosurgery Clinics of North America

Volumn 21, Issue 2, 2010, Pages 339-352

  Yee, Alan H ^a   Burns, Joseph D ^b   Wijdicks, Eelco F M ^a  

^a MAYO CLINIC   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Hyponatremia; Natriuresis; Natriuretic factors; SIADH

Indexed keywords

CONIVAPTAN; ELECTROLYTE; FLUDROCORTISONE; MINERALOCORTICOID; NATRIURETIC FACTOR; SODIUM CHLORIDE;

BLOOD VOLUME; CEREBRAL SALT WASTING; DIURESIS; ELECTROLYTE BLOOD LEVEL; ELECTROLYTE URINE LEVEL; HUMAN; HYPONATREMIA; INAPPROPRIATE VASOPRESSIN SECRETION; NATRIURESIS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SERUM OSMOLALITY; SYNDROME; URINE OSMOLALITY;

BRAIN DISEASES; CRITICAL ILLNESS; DIAGNOSIS, DIFFERENTIAL; HUMANS; HYPONATREMIA; HYPOVOLEMIA; KIDNEY; NATRIURETIC AGENTS; NATRIURETIC PEPTIDES; RENIN-ANGIOTENSIN SYSTEM; SODIUM; SYMPATHETIC NERVOUS SYSTEM; WATER-ELECTROLYTE BALANCE;

EID: 77951043679     PISSN: 10423680     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nec.2009.10.011     Document Type: Review

References (135)

1. Schwartz W.B., Bennett W., Curelop S., et al. A syndrome of renal sodium loss and hyponatremia probably resulting from inappropriate secretion of antidiuretic hormone. Am J Med 1957, 23(4):529-542.
2. Doczi T., Bende J., Huszka E., et al. Syndrome of inappropriate secretion of antidiuretic hormone after subarachnoid hemorrhage. Neurosurgery 1981, 9(4):394-397.
3. Doczi T., Tarjanyi J., Huszka E., et al. Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) after head injury. Neurosurgery 1982, 10(6 Pt 1):685-688.
4. Wise B.L. Syndrome of inappropriate antidiuretic hormone secretion after spontaneous subarachnoid hemorrhage: a reversible cause of clinical deterioration. Neurosurgery 1978, 3(3):412-414.
5. Afifi A., Joynt R., Harbison J. Inappropriate antidiuretic hormone secretion in subarachnoid hemorrhage. Trans Am Neurol Assoc 1965, 90:217-218.
6. Joynt R.J., Afifi A., Harrison J. Hyponatremia in subarachnoid hemorrhage. Arch Neurol 1965, 13(6):633-638.
7. Wijdicks E.F., Vermeulen M., ten Haaf J.A., et al. Volume depletion and natriuresis in patients with a ruptured intracranial aneurysm. Ann Neurol 1985, 18(2):211-216.
8. Nelson P.B., Seif S.M., Maroon J.C., et al. Hyponatremia in intracranial disease: perhaps not the syndrome of inappropriate secretion of antidiuretic hormone (SIADH). J Neurosurg 1981, 55(6):938-941.
9. Nelson P.B., Seif S., Gutai J., et al. Hyponatremia and natriuresis following subarachnoid hemorrhage in a monkey model. J Neurosurg 1984, 60(2):233-237.
10. Sherlock M., O'Sullivan E., Agha A., et al. The incidence and pathophysiology of hyponatraemia after subarachnoid haemorrhage. Clin Endocrinol (Oxf) 2006, 64(3):250-254.
11. Wijdicks E.F., Vermeulen M., Hijdra A., et al. Hyponatremia and cerebral infarction in patients with ruptured intracranial aneurysms: is fluid restriction harmful?. Ann Neurol 1985, 17(2):137-140.
12. Hasan D., Wijdicks E.F., Vermeulen M. Hyponatremia is associated with cerebral ischemia in patients with aneurysmal subarachnoid hemorrhage. Ann Neurol 1990, 27(1):106-108.
13. Fox J.L., Falik J.L., Shalhoub R.J. Neurosurgical hyponatremia: the role of inappropriate antidiuresis. J Neurosurg 1971, 34(4):506-514.
14. Peters J.P., Welt L.G., Sims E.A., et al. A salt-wasting syndrome associated with cerebral disease. Trans Assoc Am Physicians 1950, 63:57-64.
15. Palmer B.F. Hyponatraemia in a neurosurgical patient: syndrome of inappropriate antidiuretic hormone secretion versus cerebral salt wasting. Nephrol Dial Transplant 2000, 15(2):262-268.
16. Isotani E., Suzuki R., Tomita K., et al. Alterations in plasma concentrations of natriuretic peptides and antidiuretic hormone after subarachnoid hemorrhage. Stroke 1994, 25(11):2198-2203.
17. Wijdicks E.F., Ropper A.H., Hunnicutt E.J., et al. Atrial natriuretic factor and salt wasting after aneurysmal subarachnoid hemorrhage. Stroke 1991, 22(12):1519-1524.
18. Igarashi T., Moro N., Katayama Y., et al. Prediction of symptomatic cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage: relationship to cerebral salt wasting syndrome. Neurol Res 2007, 29(8):835-841.
19. McGirt M.J., Blessing R., Nimjee S.M., et al. Correlation of serum brain natriuretic peptide with hyponatremia and delayed ischemic neurological deficits after subarachnoid hemorrhage. Neurosurgery 2004, 54(6):1369-1373.
20. Sviri G.E., Feinsod M., Soustiel J.F. Brain natriuretic peptide and cerebral vasospasm in subarachnoid hemorrhage: clinical and TCD correlations. Stroke 2000, 31(1):118-122.
21. Berendes E., Walter M., Cullen P., et al. Secretion of brain natriuretic peptide in patients with aneurysmal subarachnoid haemorrhage. Lancet 1997, 349(9047):245-249.
22. Ganong C.A., Kappy M.S. Cerebral salt wasting in children: the need for recognition and treatment. Am J Dis Child 1993, 147(2):167-169.
23. Inoha S., Inamura T., Nakamizo A., et al. Fluid loading in rats increases serum brain natriuretic peptide concentration. Neurol Res 2001, 23(1):93-95.
24. Khurana V.G., Wijdicks E.F., Heublein D.M., et al. A pilot study of dendroaspis natriuretic peptide in aneurysmal subarachnoid hemorrhage. Neurosurgery 2004, 55(1):69-75.
25. Kikumoto K., Kubo A., Hayashi Y., et al. Increased plasma concentration of adrenomedullin in patients with subarachnoid hemorrhage. Anesth Analg 1998, 87(4):859-863.
26. Kojima J., Katayama Y., Moro N., et al. Cerebral salt wasting in subarachnoid hemorrhage rats: model, mechanism, and tool. Life Sci 2005, 76(20):2361-2370.
27. Kubo Y., Ogasawara K., Kakino S., et al. Cerebrospinal fluid adrenomedullin concentration correlates with hyponatremia and delayed ischemic neurological deficits after subarachnoid hemorrhage. Cerebrovasc Dis 2008, 25(1-2):164-169.
28. Kurokawa Y., Uede T., Ishiguro M., et al. Pathogenesis of hyponatremia following subarachnoid hemorrhage due to ruptured cerebral aneurysm. Surg Neurol 1996, 46(5):500-507. [discussion: 507-8].
29. Shimoda M., Yamada S., Yamamoto I., et al. Atrial natriuretic polypeptide in patients with subarachnoid haemorrhage due to aneurysmal rupture: correlation to hyponatremia. Acta Neurochir (Wien) 1989, 97(1-2):53-61.
30. Wijdicks E.F., Heublein D.M., Burnett J.C. Increase and uncoupling of adrenomedullin from the natriuretic peptide system in aneurysmal subarachnoid hemorrhage. J Neurosurg 2001, 94(2):252-256.
31. Vogel J.H. Aldosterone in cerebral salt wasting. Circulation 1963, 27:44-50.
32. Lu D.C., Binder D.K., Chien B., et al. Cerebral salt wasting and elevated brain natriuretic peptide levels after traumatic brain injury: 2 case reports. Surg Neurol 2008, 69(3):226-229.
33. Chang C.H., Liao J.J., Chuang C.H., et al. Recurrent hyponatremia after traumatic brain injury. Am J Med Sci 2008, 335(5):390-393.
34. Moro N., Katayama Y., Igarashi T., et al. Hyponatremia in patients with traumatic brain injury: incidence, mechanism, and response to sodium supplementation or retention therapy with hydrocortisone. Surg Neurol 2007, 68(4):387-393.
35. Vespa P. Cerebral salt wasting after traumatic brain injury: an important critical care treatment issue. Surg Neurol 2008, 69(3):230-232.
36. Lee P., Jones G.R., Center J.R. Successful treatment of adult cerebral salt wasting with fludrocortisone. Arch Intern Med 2008, 168(3):325-326.
37. Jimenez R., Casado-Flores J., Nieto M., et al. Cerebral salt wasting syndrome in children with acute central nervous system injury. Pediatr Neurol 2006, 35(4):261-263.
38. Steelman R., Corbitt B., Pate M.F. Early onset of cerebral salt wasting in a patient with head and facial injuries. J Oral Maxillofac Surg 2006, 64(4):746-747.
39. Berkenbosch J.W., Lentz C.W., Jimenez D.F., et al. Cerebral salt wasting syndrome following brain injury in three pediatric patients: suggestions for rapid diagnosis and therapy. Pediatr Neurosurg 2002, 36(2):75-79.
40. Powner D.J., Boccalandro C. Adrenal insufficiency following traumatic brain injury in adults. Curr Opin Crit Care 2008, 14(2):163-166.
41. Brimioulle S., Orellana-Jimenez C., Aminian A., et al. Hyponatremia in neurological patients: cerebral salt wasting versus inappropriate antidiuretic hormone secretion. Intensive Care Med 2008, 34(1):125-131.
42. Powner D.J., Boccalandro C., Alp M.S., et al. Endocrine failure after traumatic brain injury in adults. Neurocrit Care 2006, 5(1):61-70.
43. Penney M.D., Walters G., Wilkins D.G. Hyponatraemia in patients with head injury. Intensive Care Med 1979, 5(1):23-26.
44. Roca-Ribas F., Ninno J.E., Gasperin A., et al. Cerebral salt wasting syndrome as a postoperative complication after surgical resection of acoustic neuroma. Otol Neurotol 2002, 23(6):992-995.
45. Poon W.S., Lolin Y.I., Yeung T.F., et al. Water and sodium disorders following surgical excision of pituitary region tumours. Acta Neurochir (Wien) 1996, 138(8):921-927.
46. Oster J.R., Perez G.O., Larios O., et al. Cerebral salt wasting in a man with carcinomatous meningitis. Arch Intern Med 1983, 143(11):2187-2188.
47. Oruckaptan H.H., Ozisik P., Akalan N. Prolonged cerebral salt wasting syndrome associated with the intraventricular dissemination of brain tumors: report of two cases and review of the literature. Pediatr Neurosurg 2000, 33(1):16-20.
48. Kim J.H., Kang J.K., Lee S.A. Hydrocephalus and hyponatremia as the presenting manifestations of primary CNS lymphoma. Eur Neurol 2006, 55(1):39-41.
49. Diringer M., Ladenson P.W., Borel C., et al. Sodium and water regulation in a patient with cerebral salt wasting. Arch Neurol 1989, 46(8):928-930.
50. Atkin S.L., Coady A.M., White M.C., et al. Hyponatraemia secondary to cerebral salt wasting syndrome following routine pituitary surgery. Eur J Endocrinol 1996, 135(2):245-247.
51. Cort J.H. Cerebral salt wasting. Lancet 1954, 266(6815):752-754.
52. Moller K., Larsen F.S., Bie P., et al. The syndrome of inappropriate secretion of antidiuretic hormone and fluid restriction in meningitis: how strong is the evidence?. Scand J Infect Dis 2001, 33(1):13-26.
53. Narotam P.K., Kemp M., Buck R., et al. Hyponatremic natriuretic syndrome in tuberculous meningitis: the probable role of atrial natriuretic peptide. Neurosurgery 1994, 34(6):982-988. [discussion: 988].
54. Huang S.M., Chen C.C., Chiu P.C., et al. Tuberculous meningitis complicated with hydrocephalus and cerebral salt wasting syndrome in a three-year-old boy. Pediatr Infect Dis J 2004, 23(9):884-886.
55. Brookes M.J., Gould T.H. Cerebral salt wasting syndrome in meningoencephalitis: a case report. J Neurol Neurosurg Psychiatr 2003, 74(2):277.
56. Ti L.K., Kang S.C., Cheong K.F. Acute hyponatraemia secondary to cerebral salt wasting syndrome in a patient with tuberculous meningitis. Anaesth Intensive Care 1998, 26(4):420-423.
57. Erduran E., Mocan H., Aslan Y. Another cause of hyponatraemia in patients with bacterial meningitis: cerebral salt wasting. Acta Paediatr 1997, 86(10):1150-1151.
58. Celik U.S., Alabaz D., Yildizdas D., et al. Cerebral salt wasting in tuberculous meningitis: treatment with fludrocortisone. Ann Trop Paediatr 2005, 25(4):297-302.
59. Singhi S.C., Singhi P.D., Srinivas B., et al. Fluid restriction does not improve the outcome of acute meningitis. Pediatr Infect Dis J 1995, 14(6):495-503.
60. Chao Y.N., Chiu N.C., Huang F.Y. Clinical features and prognostic factors in childhood pneumococcal meningitis. J Microbiol Immunol Infect 2008, 41(1):48-53.
61. Olson B.R., Gumowski J., Rubino D., et al. Pathophysiology of hyponatremia after transsphenoidal pituitary surgery. J Neurosurg 1997, 87(4):499-507.
62. Papadimitriou D.T., Spiteri A., Pagnier A., et al. Mineralocorticoid deficiency in post-operative cerebral salt wasting. J Pediatr Endocrinol Metab 2007, 20(10):1145-1150.
63. Hensen J., Henig A., Fahlbusch R., et al. Prevalence, predictors and patterns of postoperative polyuria and hyponatraemia in the immediate course after transsphenoidal surgery for pituitary adenomas. Clin Endocrinol (Oxf) 1999, 50(4):431-439.
64. Arieff A.I. Hyponatremia, convulsions, respiratory arrest, and permanent brain damage after elective surgery in healthy women. N Engl J Med 1986, 314(24):1529-1535.
65. Wijdicks E.F., Vermeulen M., van Brummelen P., et al. The effect of fludrocortisone acetate on plasma volume and natriuresis in patients with aneurysmal subarachnoid hemorrhage. Clin Neurol Neurosurg 1988, 90(3):209-214.
66. Carlotti A.P., Bohn D., Rutka J.T., et al. A method to estimate urinary electrolyte excretion in patients at risk for developing cerebral salt wasting. J Neurosurg 2001, 95(3):420-424.
67. Ishikawa S.E., Saito T., Kaneko K., et al. Hyponatremia responsive to fludrocortisone acetate in elderly patients after head injury. Ann Intern Med 1987, 106(2):187-191.
68. Donati-Genet P.C., Dubuis J.M., Girardin E., et al. Acute symptomatic hyponatremia and cerebral salt wasting after head injury: an important clinical entity. J Pediatr Surg 2001, 36(7):1094-1097.
69. Kanakriyeh M., Carvajal H.F., Vallone A.M. Initial fluid therapy for children with meningitis with consideration of the syndrome of inappropriate anti-diuretic hormone. Clin Pediatr (Phila) 1987, 26(3):126-130.
70. Maconochie I., Baumer H., Stewart M.E. Fluid therapy for acute bacterial meningitis. Cochrane Database Syst Rev 2008, (1). CD004786.
71. Lavoie J.L., Sigmund C.D. Minireview: overview of the renin-angiotensin system-an endocrine and paracrine system. Endocrinology 2003, 144(6):2179-2183.
72. Williams G.H., Dluhy R.G. Disorders of the adrenal cortex. Harrison's principles of internal medicine 2001, 2087-2089. McGraw-Hill Medical Publishing Division, New York. 15th edition. E. Braunwald, A.S. Fauci, D.L. Kasper (Eds.).
73. Paul M., Poyan Mehr A., Kreutz R. Physiology of local renin-angiotensin systems. Physiol Rev 2006, 86(3):747-803.
74. Bader M., Peters J., Baltatu O., et al. Tissue renin-angiotensin systems: new insights from experimental animal models in hypertension research. J Mol Med 2001, 79(2-3):76-102.
75. Morimoto S., Sigmund C.D. Angiotensin mutant mice: a focus on the brain renin-angiotensin system. Neuropeptides 2002, 36(2-3):194-200.
76. Steckelings U.M., Obermuller N., Bottari S.P., et al. Brain angiotensin: receptors, actions and possible role in hypertension. Pharmacol Toxicol 1992, 70(6 Pt 2):S23-S27.
77. Steckelings U., Lebrun C., Qadri F., et al. Role of brain angiotensin in cardiovascular regulation. J Cardiovasc Pharmacol 1992, 19(Suppl 6):S72-S79.
78. DiBona G.F. Nervous kidney: interaction between renal sympathetic nerves and the renin-angiotensin system in the control of renal function. Hypertension 2000, 36(6):1083-1088.
79. Muller J., Barajas L. Electron microscopic and histochemical evidence for a tubular innervation in the renal cortex of the monkey. J Ultrastruct Res 1972, 41(5):533-549.
80. DiBona G.F. Physiology in perspective: the wisdom of the body. Neural control of the kidney. Am J Physiol Regul Integr Comp Physiol 2005, 289(3):R633-R641.
81. DiBona G.F. Central sympathoexcitatory actions of angiotensin II: role of type 1 angiotensin II receptors. J Am Soc Nephrol 1999, 10(Suppl 11):S90-S94.
82. Reid I.A. Interactions between ANG II, sympathetic nervous system, and baroreceptor reflexes in regulation of blood pressure. Am J Physiol 1992, 262(6 Pt 1):E763-E778.
83. Benarroch E., Westmoreland B., Daube J., et al. The internal regulation system. Medical neurosciences: an approach to anatomy, pathology, and physiology by systems and levels 1998, Lippincott Williams & Wilkins, Hagerstown (MD), 264-9. 4th edition.
84. DiBona G.F. Neural control of renal function in health and disease. Clin Auton Res 1994, 4(1-2):69-74.
85. Samuels M.A. The brain-heart connection. Circulation 2007, 116(1):77-84.
86. de Bold A.J., Borenstein H.B., Veress A.T., et al. A rapid and potent natriuretic response to intravenous injection of atrial myocardial extract in rats. Life Sci 1981, 28(1):89-94.
87. Levin E.R., Gardner D.G., Samson W.K. Natriuretic peptides. N Engl J Med 1998, 339(5):321-328.
88. Lisy O., Lainchbury J.G., Leskinen H., et al. Therapeutic actions of a new synthetic vasoactive and natriuretic peptide, dendroaspis natriuretic peptide, in experimental severe congestive heart failure. Hypertension 2001, 37(4):1089-1094.
89. Lisy O., Jougasaki M., Heublein D.M., et al. Renal actions of synthetic dendroaspis natriuretic peptide. Kidney Int 1999, 56(2):502-508.
90. Del Ry S., Cabiati M., Lionetti V., et al. Expression of C-type natriuretic peptide and of its receptor NPR-B in normal and failing heart. Peptides 2008, 29(12):2208-2215.
91. Sudoh T., Minamino N., Kangawa K., et al. C-type natriuretic peptide (CNP): a new member of natriuretic peptide family identified in porcine brain. Biochem Biophys Res Commun 1990, 168(2):863-870.
92. Suga S., Nakao K., Hosoda K., et al. Receptor selectivity of natriuretic peptide family, atrial natriuretic peptide, brain natriuretic peptide, and C-type natriuretic peptide. Endocrinology 1992, 130(1):229-239.
93. Cao L.H., Yang X.L. Natriuretic peptides and their receptors in the central nervous system. Prog Neurobiol 2008, 84(3):234-248.
94. Schultz H.D., Gardner D.G., Deschepper C.F., et al. Vagal C-fiber blockade abolishes sympathetic inhibition by atrial natriuretic factor. Am J Physiol 1988, 255(1 Pt 2):R6-13.
95. Schultz H.D., Steele M.K., Gardner D.G. Central administration of atrial peptide decreases sympathetic outflow in rats. Am J Physiol 1990, 258(5 Pt 2):R1250-R1256.
96. Steele M.K., Gardner D.G., Xie P.L., et al. Interactions between ANP and ANG II in regulating blood pressure and sympathetic outflow. Am J Physiol 1991, 260(6 Pt 2):R1145-R1151.
97. Harris P.J., Thomas D., Morgan T.O. Atrial natriuretic peptide inhibits angiotensin-stimulated proximal tubular sodium and water reabsorption. Nature 1987, 326(6114):697-698.
98. Dillingham M.A., Anderson R.J. Inhibition of vasopressin action by atrial natriuretic factor. Science 1986, 231(4745):1572-1573.
99. Saper C.B., Hurley K.M., Moga M.M., et al. Brain natriuretic peptides: differential localization of a new family of neuropeptides. Neurosci Lett 1989, 96(1):29-34.
100. Lee Y.J., Lin S.R., Shin S.J., et al. Brain natriuretic peptide is synthesized in the human adrenal medulla and its messenger ribonucleic acid expression along with that of atrial natriuretic peptide are enhanced in patients with primary aldosteronism. J Clin Endocrinol Metab 1994, 79(5):1476-1482.
101. Maack T., Suzuki M., Almeida F.A., et al. Physiological role of silent receptors of atrial natriuretic factor. Science 1987, 238(4827):675-678.
102. Johns D.G., Ao Z., Heidrich B.J., et al. Dendroaspis natriuretic peptide binds to the natriuretic peptide clearance receptor. Biochem Biophys Res Commun 2007, 358(1):145-149.
103. Tomida M., Muraki M., Uemura K., et al. Plasma concentrations of brain natriuretic peptide in patients with subarachnoid hemorrhage. Stroke 1998, 29(8):1584-1587.
104. Espiner E.A., Leikis R., Ferch R.D., et al. The neuro-cardio-endocrine response to acute subarachnoid haemorrhage. Clin Endocrinol (Oxf) 2002, 56(5):629-635.
105. Rosenfeld J.V., Barnett G.H., Sila C.A., et al. The effect of subarachnoid hemorrhage on blood and CSF atrial natriuretic factor. J Neurosurg 1989, 71(1):32-37.
106. Takahashi K., Totsune K., Sone M., et al. Human brain natriuretic peptide-like immunoreactivity in human brain. Peptides 1992, 13(1):121-123.
107. Doczi T., Joo F., Vecsernyes M., et al. Increased concentration of atrial natriuretic factor in the cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage and raised intracranial pressure. Neurosurgery 1988, 23(1):16-19.
108. Iltumur K., Yavavli A., Apak I., et al. Elevated plasma N-terminal pro-brain natriuretic peptide levels in acute ischemic stroke. Am Heart J 2006, 151(5):1115-1122.
109. Lang M.G., Paterno R., Faraci F.M., et al. Mechanisms of adrenomedullin-induced dilatation of cerebral arterioles. Stroke 1997, 28(1):181-185.
110. Dogan A., Suzuki Y., Koketsu N., et al. Intravenous infusion of adrenomedullin and increase in regional cerebral blood flow and prevention of ischemic brain injury after middle cerebral artery occlusion in rats. J Cereb Blood Flow Metab 1997, 17(1):19-25.
111. Kitamura K., Kangawa K., Kawamoto M., et al. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun 1993, 192(2):553-560.
112. Satoh F., Takahashi K., Murakami O., et al. Adrenomedullin in human brain, adrenal glands and tumor tissues of pheochromocytoma, ganglioneuroblastoma and neuroblastoma. J Clin Endocrinol Metab 1995, 80(5):1750-1752.
113. Satoh F., Takahashi K., Murakami O., et al. Immunocytochemical localization of adrenomedullin-like immunoreactivity in the human hypothalamus and the adrenal gland. Neurosci Lett 1996, 203(3):207-210.
114. Saita M., Shimokawa A., Kunitake T., et al. Central actions of adrenomedullin on cardiovascular parameters and sympathetic outflow in conscious rats. Am J Physiol 1998, 274(4 Pt 2):R979-R984.
115. Adrogue H.J., Madias N.E. Hyponatremia. N Engl J Med 2000, 342(21):1581-1589.
116. Smith D.M., McKenna K., Thompson C.J. Hyponatraemia. Clin Endocrinol (Oxf) 2000, 52(6):667-678.
117. Janicic N., Verbalis J.G. Evaluation and management of hypo-osmolality in hospitalized patients. Endocrinol Metab Clin North Am 2003, 32(2):459-481. vii.
118. Sterns R.H., Silver S.M. Cerebral salt wasting versus SIADH: what difference?. J Am Soc Nephrol 2008, 19(2):194-196.
119. Chung H.M., Kluge R., Schrier R.W., et al. Clinical assessment of extracellular fluid volume in hyponatremia. Am J Med 1987, 83(5):905-908.
120. McGee S., Abernethy W.B., Simel D.L. The rational clinical examination. Is this patient hypovolemic?. JAMA 1999, 281(11):1022-1029.
121. von Bismarck P., Ankermann T., Eggert P., et al. Diagnosis and management of cerebral salt wasting (CSW) in children: the role of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP). Childs Nerv Syst 2006, 22(10):1275-1281.
122. Maesaka J.K., Miyawaki N., Palaia T., et al. Renal salt wasting without cerebral disease: diagnostic value of urate determinations in hyponatremia. Kidney Int 2007, 71(8):822-826.
123. Maesaka J.K., Gupta S., Fishbane S. Cerebral salt-wasting syndrome: does it exist?. Nephron 1999, 82(2):100-109.
124. Damaraju S.C., Rajshekhar V., Chandy M.J. Validation study of a central venous pressure-based protocol for the management of neurosurgical patients with hyponatremia and natriuresis. Neurosurgery 1997, 40(2):312-316. [discussion: 316-7].
125. Kumar A., Anel R., Bunnell E., et al. Pulmonary artery occlusion pressure and central venous pressure fail to predict ventricular filling volume, cardiac performance, or the response to volume infusion in normal subjects. Crit Care Med 2004, 32(3):691-699.
126. McGee D.C., Gould M.K. Preventing complications of central venous catheterization. N Engl J Med 2003, 348(12):1123-1133.
127. Solomon R.A., Post K.D., McMurtry J.G. Depression of circulating blood volume in patients after subarachnoid hemorrhage: implications for the management of symptomatic vasospasm. Neurosurgery 1984, 15(3):354-361.
128. Diringer M.N., Wu K.C., Verbalis J.G., et al. Hypervolemic therapy prevents volume contraction but not hyponatremia following subarachnoid hemorrhage. Ann Neurol 1992, 31(5):543-550.
129. Mori T., Katayama Y., Kawamata T., et al. Improved efficiency of hypervolemic therapy with inhibition of natriuresis by fludrocortisone in patients with aneurysmal subarachnoid hemorrhage. J Neurosurg 1999, 91(6):947-952.
130. Kinik S.T., Kandemir N., Baykan A., et al. Fludrocortisone treatment in a child with severe cerebral salt wasting. Pediatr Neurosurg 2001, 35(4):216-219.
131. Katayama Y., Haraoka J., Hirabayashi H., et al. A randomized controlled trial of hydrocortisone against hyponatremia in patients with aneurysmal subarachnoid hemorrhage. Stroke 2007, 38(8):2373-2375.
132. Hasan D., Lindsay K.W., Wijdicks E.F., et al. Effect of fludrocortisone acetate in patients with subarachnoid hemorrhage. Stroke 1989, 20(9):1156-1161.
133. Decaux G., Soupart A., Vassart G. Non-peptide arginine-vasopressin antagonists: the vaptans. Lancet 2008, 371(9624):1624-1632.
134. Murphy T., Dhar R., Diringer M. Conivaptan bolus dosing for the correction of hyponatremia in the neurointensive care unit. Neurocrit Care 2009, 11(1):14-19.
135. Annane D., Decaux G., Smith N. Efficacy and safety of oral conivaptan, a vasopressin-receptor antagonist, evaluated in a randomized, controlled trial in patients with euvolemic or hypervolemic hyponatremia. Am J Med Sci 2009, 337(1):28-36.