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Volumn 7, Issue 3, 2008, Pages 178-183

Colon cancer: Update on adjuvant therapy

Author keywords

Bevacizumab; Capecitabine; Elderly patients; Fluoropyrimidines; Irinotecan; Oxaliplatin

Indexed keywords

5 CHLORO 2,4 DIHYDROXYPYRIDINE PLUS OXONATE POTASSIUM PLUS TEGAFUR; BEVACIZUMAB; BORTEZOMIB; CAPECITABINE; CETUXIMAB; ERLOTINIB; FLUOROPYRIMIDINE DERIVATIVE; FLUOROURACIL; FOLINIC ACID; GEFITINIB; IRINOTECAN; N (3,3 DIMETHYL 6 INDOLINYL) 2 (4 PYRIDINYLMETHYLAMINO)NICOTINAMIDE; OXALIPLATIN; PANITUMUMAB; SUNITINIB; TEGAFUR; URACIL;

EID: 44449091598     PISSN: 15330028     EISSN: None     Source Type: Journal    
DOI: 10.3816/CCC.2008.n.023     Document Type: Review
Times cited : (40)

References (71)
  • 2
    • 21244497388 scopus 로고    scopus 로고
    • Capecitabine as adjuvant treatment for stage III colon cancer
    • Twelves C, Wong A, Nowacki MP, et al. Capecitabine as adjuvant treatment for stage III colon cancer. N Engl J Med 2005; 352:2696-704.
    • (2005) N Engl J Med , vol.352 , pp. 2696-2704
    • Twelves, C.1    Wong, A.2    Nowacki, M.P.3
  • 3
    • 36749058729 scopus 로고    scopus 로고
    • Oxaliplatin/5FU/LV in the adjuvant treatment of stage III colon cancer: Efficacy results with a median follow-up of 4 years
    • 16 suppl):246s Abstract 3501
    • de Gramont A, Boni C, Navarro M, et al. Oxaliplatin/5FU/LV in the adjuvant treatment of stage III colon cancer: efficacy results with a median follow-up of 4 years. J Clin Oncol 2005; 23(16 suppl):246s (Abstract 3501).
    • (2005) J Clin Oncol , pp. 23
    • de Gramont, A.1    Boni, C.2    Navarro, M.3
  • 4
    • 34250210799 scopus 로고    scopus 로고
    • Oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: Results from NSABP C-07
    • Kuebler JP, Wieand HS, O'Connell MJ, et al. Oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: results from NSABP C-07. J Clin Oncol 2007; 25:2198-204.
    • (2007) J Clin Oncol , vol.25 , pp. 2198-2204
    • Kuebler, J.P.1    Wieand, H.S.2    O'Connell, M.J.3
  • 5
    • 33947267505 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of oxaliplatin compared with 5-fluorouracil/leucovorin in adjuvant treatment of stage III colon cancer in the US
    • Aballea S, Chancellor JV, Raikou M, et al. Cost-effectiveness analysis of oxaliplatin compared with 5-fluorouracil/leucovorin in adjuvant treatment of stage III colon cancer in the US. Cancer 2007; 109:1082-9.
    • (2007) Cancer , vol.109 , pp. 1082-1089
    • Aballea, S.1    Chancellor, J.V.2    Raikou, M.3
  • 6
    • 0029644482 scopus 로고
    • Investigators. Efficacy of adjuvant fluorouracil and folinic acid in colon cancer
    • International Multicentre Pooled Analysis of Colon Cancer Trials IMPACT
    • International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) Investigators. Efficacy of adjuvant fluorouracil and folinic acid in colon cancer. Lancet 1995; 345:939-44.
    • (1995) Lancet , vol.345 , pp. 939-944
  • 7
    • 0031022988 scopus 로고    scopus 로고
    • Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer
    • O'Connell MJ, Mailliard JA, Kahn MJ, et al. Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer. J Clin Oncol 1997; 15:246-50.
    • (1997) J Clin Oncol , vol.15 , pp. 246-250
    • O'Connell, M.J.1    Mailliard, J.A.2    Kahn, M.J.3
  • 8
    • 0031982505 scopus 로고    scopus 로고
    • Prospectively randomized trial of postoperative adjuvant chemotherapy in patients with high-risk colon cancer
    • O'Connell MJ, Laurie JA, Kahn M, et al. Prospectively randomized trial of postoperative adjuvant chemotherapy in patients with high-risk colon cancer. J Clin Oncol 1998; 16:295-300.
    • (1998) J Clin Oncol , vol.16 , pp. 295-300
    • O'Connell, M.J.1    Laurie, J.A.2    Kahn, M.3
  • 9
    • 0042887580 scopus 로고    scopus 로고
    • Semimonthly versus monthly regimen of fluorouracil and leucovorin administered for 24 or 36 weeks as adjuvant therapy in stage II and III colon cancer: Results of a randomized trial
    • Andre T, Colin P, Louvet C, et al. Semimonthly versus monthly regimen of fluorouracil and leucovorin administered for 24 or 36 weeks as adjuvant therapy in stage II and III colon cancer: results of a randomized trial. J Clin Oncol 2003; 21:2896-903.
    • (2003) J Clin Oncol , vol.21 , pp. 2896-2903
    • Andre, T.1    Colin, P.2    Louvet, C.3
  • 10
    • 34548160680 scopus 로고    scopus 로고
    • Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: Results of CALGB 89803
    • Saltz LB, Niedzwiecki D, Hollis D, et al. Irinotecan fluorouracil plus leucovorin is not superior to fluorouracil plus leucovorin alone as adjuvant treatment for stage III colon cancer: results of CALGB 89803. J Clin Oncol 2007; 25:3456-61.
    • (2007) J Clin Oncol , vol.25 , pp. 3456-3461
    • Saltz, L.B.1    Niedzwiecki, D.2    Hollis, D.3
  • 11
    • 84898694103 scopus 로고    scopus 로고
    • Ychou M, Raoul J, Douillard J, et al. A phase III randomized trial of LV5FU2+CPT-11 vs. LV5FU2 alone in adjuvant high risk colon cancer (FNCLCC Accord02/FFCD9802). J Clin Oncol 2005; 23(16 suppl):246s (Abstract 3502).
    • Ychou M, Raoul J, Douillard J, et al. A phase III randomized trial of LV5FU2+CPT-11 vs. LV5FU2 alone in adjuvant high risk colon cancer (FNCLCC Accord02/FFCD9802). J Clin Oncol 2005; 23(16 suppl):246s (Abstract 3502).
  • 12
    • 84898699753 scopus 로고    scopus 로고
    • Van Cutsem E, Labianca R, Hossfeld D, et al. Randomized phase III trial comparing infused irinotecan / 5-fluorouracil (5-FU)/folinic acid (IF) versus 5-FU/FA (F) in stage III colon cancer patients (pts). (PETACC 3). J Clin Oncol 2005: 23(16 suppl):3s (Abstract LBA8).
    • Van Cutsem E, Labianca R, Hossfeld D, et al. Randomized phase III trial comparing infused irinotecan / 5-fluorouracil (5-FU)/folinic acid (IF) versus 5-FU/FA (F) in stage III colon cancer patients (pts). (PETACC 3). J Clin Oncol 2005: 23(16 suppl):3s (Abstract LBA8).
  • 13
    • 2542615200 scopus 로고    scopus 로고
    • Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer
    • Andre T, Boni C, Mounedji-Boudiaf L, et al. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Engl J Med 2004; 350:2343-51.
    • (2004) N Engl J Med , vol.350 , pp. 2343-2351
    • Andre, T.1    Boni, C.2    Mounedji-Boudiaf, L.3
  • 14
    • 85031377237 scopus 로고    scopus 로고
    • de Gramont A, Boni C, Navarro M, et al. Oxaliplatin/5FU/LV in adjuvant colon cancer: updated efficacy results of the MOSAIC trial, including survival, with a median follow-up of six years. J Clin Oncol 2007; 25(18 suppl): 165s (Abstract 4007).
    • de Gramont A, Boni C, Navarro M, et al. Oxaliplatin/5FU/LV in adjuvant colon cancer: updated efficacy results of the MOSAIC trial, including survival, with a median follow-up of six years. J Clin Oncol 2007; 25(18 suppl): 165s (Abstract 4007).
  • 15
    • 0034712536 scopus 로고    scopus 로고
    • Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: A multicentre randomised trial
    • Douillard JY, Cunningham D, Roth AD, et al. Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial. Lancet 2000; 355:1041-7.
    • (2000) Lancet , vol.355 , pp. 1041-1047
    • Douillard, J.Y.1    Cunningham, D.2    Roth, A.D.3
  • 16
    • 1342290189 scopus 로고    scopus 로고
    • FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: A randomized GERCOR study
    • Tournigand C, Andre T, Achille E, et al. FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study. J Clin Oncol 2004; 22:229-37.
    • (2004) J Clin Oncol , vol.22 , pp. 229-237
    • Tournigand, C.1    Andre, T.2    Achille, E.3
  • 17
    • 24644457747 scopus 로고    scopus 로고
    • Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: A multicenter study of the Gruppo Oncologico Dell'Italia Meridionale
    • Colucci G, Gebbia V, Paoletti G, et al. Phase III randomized trial of FOLFIRI versus FOLFOX4 in the treatment of advanced colorectal cancer: a multicenter study of the Gruppo Oncologico Dell'Italia Meridionale. J Clin Oncol 2005; 23:4866-75.
    • (2005) J Clin Oncol , vol.23 , pp. 4866-4875
    • Colucci, G.1    Gebbia, V.2    Paoletti, G.3
  • 18
    • 36048960109 scopus 로고    scopus 로고
    • Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: Results from the BICC-C study
    • Fuchs CS, Marshall J, Mitchell E, et al. Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C study. J Clin Oncol 2007; 25:4779-86.
    • (2007) J Clin Oncol , vol.25 , pp. 4779-4786
    • Fuchs, C.S.1    Marshall, J.2    Mitchell, E.3
  • 19
    • 1842569206 scopus 로고    scopus 로고
    • A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer
    • Goldberg RM, Sargent DJ, Morton RF, et al. A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2004; 22:23-30.
    • (2004) J Clin Oncol , vol.22 , pp. 23-30
    • Goldberg, R.M.1    Sargent, D.J.2    Morton, R.F.3
  • 20
    • 33746805967 scopus 로고    scopus 로고
    • Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: A North American Intergroup trial
    • Goldberg RM, Sargent DJ, Morton RF, et al. Randomized controlled trial of reduced-dose bolus fluorouracil plus leucovorin and irinotecan or infused fluorouracil plus leucovorin and oxaliplatin in patients with previously untreated metastatic colorectal cancer: a North American Intergroup trial. J Clin Oncol 2006; 24:3347-53.
    • (2006) J Clin Oncol , vol.24 , pp. 3347-3353
    • Goldberg, R.M.1    Sargent, D.J.2    Morton, R.F.3
  • 21
    • 85031376138 scopus 로고    scopus 로고
    • Roth AD, Tejpar S, Yan P, et al. Tissue biomarkers (BIOM) in colon cancer (COC): the translational study on the randomized phase III trial comparing infused irinotecan/5-fluorouracil (5-FU)/folinic acid (FA) to 5-FU/FA in stage II-III COC patients (pts). J Clin Oncol 2007; 25(18 suppl):169s (Abstract 4022).
    • Roth AD, Tejpar S, Yan P, et al. Tissue biomarkers (BIOM) in colon cancer (COC): the translational study on the randomized phase III trial comparing infused irinotecan/5-fluorouracil (5-FU)/folinic acid (FA) to 5-FU/FA in stage II-III COC patients (pts). J Clin Oncol 2007; 25(18 suppl):169s (Abstract 4022).
  • 22
    • 85031389786 scopus 로고    scopus 로고
    • Bertagnolli MM, Compton CC, Niedzwiecki D, et al. Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, 5-fluorouracil and leucovorin in stage III colon cancer. J Clin Oncol 2006; 24(18 suppl):541s (Abstract 10003).
    • Bertagnolli MM, Compton CC, Niedzwiecki D, et al. Microsatellite instability predicts improved response to adjuvant therapy with irinotecan, 5-fluorouracil and leucovorin in stage III colon cancer. J Clin Oncol 2006; 24(18 suppl):541s (Abstract 10003).
  • 23
    • 34147103678 scopus 로고    scopus 로고
    • Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer
    • Van Cutsem E, Peeters M, Siena S, et al. Open-label phase III trial of panitumumab plus best supportive care compared with best supportive care alone in patients with chemotherapy-refractory metastatic colorectal cancer. J Clin Oncol 2007; 25:1658-64.
    • (2007) J Clin Oncol , vol.25 , pp. 1658-1664
    • Van Cutsem, E.1    Peeters, M.2    Siena, S.3
  • 24
    • 84898690312 scopus 로고    scopus 로고
    • Kohne C, Bajerta E, Lin E, et al. Final results of CONFIRM 2: a multinational, randomized, double-blind, phase III study in 2nd line patients (pts) with metastatic colorectal cancer (mCRC) receiving FOLFOX4 and PTK787/ZK 222584 (PTK/ZK) or placebo. J Clin Oncol 2007; 25(18 suppl):171s (Abstract 4033).
    • Kohne C, Bajerta E, Lin E, et al. Final results of CONFIRM 2: a multinational, randomized, double-blind, phase III study in 2nd line patients (pts) with metastatic colorectal cancer (mCRC) receiving FOLFOX4 and PTK787/ZK 222584 (PTK/ZK) or placebo. J Clin Oncol 2007; 25(18 suppl):171s (Abstract 4033).
  • 25
    • 35948981296 scopus 로고    scopus 로고
    • A phase I study of sunitinib in combination with FOLFIRI chemotherapy in treatment-naive, metastatic colorectal cancer
    • Presented at: January 19-21, Orlando, FL. Abstract 319
    • Starling N, Cunningham D, Vazquez F, et al. A phase I study of sunitinib in combination with FOLFIRI chemotherapy in treatment-naive, metastatic colorectal cancer. Presented at: 2007 American Society of Clinical Oncology Gastrointestinal Cancers Symposium; January 19-21, 2007; Orlando, FL. Abstract 319.
    • (2007) 2007 American Society of Clinical Oncology Gastrointestinal Cancers Symposium
    • Starling, N.1    Cunningham, D.2    Vazquez, F.3
  • 26
    • 85031391146 scopus 로고    scopus 로고
    • Schwartzberg LS, Hurwitz H, Stephenson J, et al. Safety and pharmacokinetics (PK) of AMG 706 with panitumumab plus FOLFIRI or FOLFOX for the treatment of patients (pts) with metastatic colorectal cancer (mCRC). J Clin Oncol 2007; 25(18 suppl):183s (Abstract 4081).
    • Schwartzberg LS, Hurwitz H, Stephenson J, et al. Safety and pharmacokinetics (PK) of AMG 706 with panitumumab plus FOLFIRI or FOLFOX for the treatment of patients (pts) with metastatic colorectal cancer (mCRC). J Clin Oncol 2007; 25(18 suppl):183s (Abstract 4081).
  • 27
    • 85031377076 scopus 로고    scopus 로고
    • Schwartzberg LS, Hurwitz H, Stephenson J, et al. Safety and pharmacokinetics (PK) of AMG 706 with panitumumab and FOLFIRI or FOLFOX for the treatment of patients (pts) with metastatic colorectal cancer (mCRC). J Clin Oncol 2007; 25(18 suppl):183s (Abstract 4081).
    • Schwartzberg LS, Hurwitz H, Stephenson J, et al. Safety and pharmacokinetics (PK) of AMG 706 with panitumumab and FOLFIRI or FOLFOX for the treatment of patients (pts) with metastatic colorectal cancer (mCRC). J Clin Oncol 2007; 25(18 suppl):183s (Abstract 4081).
  • 28
    • 84898695184 scopus 로고    scopus 로고
    • Vieitez J, Valladares M, Pelaez I, et al. A randomised, placebo-controlled, double-blind phase II study of raltitrexed and gefitinib vs raltitrexed alone as 2nd line chemotherapy in subjects with advanced colorectal cancer (CRC). GON group study (Grupo Oncologico del Norte). J Clin Oncol 2007; 25(18 suppl):626s (Abstract 14523).
    • Vieitez J, Valladares M, Pelaez I, et al. A randomised, placebo-controlled, double-blind phase II study of raltitrexed and gefitinib vs raltitrexed alone as 2nd line chemotherapy in subjects with advanced colorectal cancer (CRC). GON group study (Grupo Oncologico del Norte). J Clin Oncol 2007; 25(18 suppl):626s (Abstract 14523).
  • 29
    • 34547868121 scopus 로고    scopus 로고
    • First clinical experience of orally active epidermal growth factor receptor inhibitor combined with simplified FOLFOX6 as first-line treatment for metastatic colorectal cancer
    • Zampino MG, Magni E, Massacesi C, et al. First clinical experience of orally active epidermal growth factor receptor inhibitor combined with simplified FOLFOX6 as first-line treatment for metastatic colorectal cancer. Cancer 2007; 110:752-8.
    • (2007) Cancer , vol.110 , pp. 752-758
    • Zampino, M.G.1    Magni, E.2    Massacesi, C.3
  • 30
    • 33845761886 scopus 로고    scopus 로고
    • Gefitinib in combination with 5-fluorouracil (5-FU)/folinic acid and irinotecan in patients with 5-FU/oxaliplatin- refractory colorectal cancer: A phase I/II study of the Arbeitsgemeinschaft für Internistische Onkologie (AIO)
    • Hofheinz RD, Kubicka S, Wollert J, et al. Gefitinib in combination with 5-fluorouracil (5-FU)/folinic acid and irinotecan in patients with 5-FU/oxaliplatin- refractory colorectal cancer: a phase I/II study of the Arbeitsgemeinschaft für Internistische Onkologie (AIO). Onkologie 2006; 29:563-7.
    • (2006) Onkologie , vol.29 , pp. 563-567
    • Hofheinz, R.D.1    Kubicka, S.2    Wollert, J.3
  • 31
    • 85031389001 scopus 로고    scopus 로고
    • Vincent M, Kerr I, Dingle B, et al. Capecitabine (X) compared to X + erlotinib (E) as first-line treatment in patients (pts) with metastatic colorectal cancer (MCRC): interim efficacy results from a randomized phase II study. J Clin Oncol 2007; 25(18 suppl):630s (Abstract 14560).
    • Vincent M, Kerr I, Dingle B, et al. Capecitabine (X) compared to X + erlotinib (E) as first-line treatment in patients (pts) with metastatic colorectal cancer (MCRC): interim efficacy results from a randomized phase II study. J Clin Oncol 2007; 25(18 suppl):630s (Abstract 14560).
  • 32
    • 84898696781 scopus 로고    scopus 로고
    • Tournigand C, Lledo G, Delord J, et al. Modified (m)FOLFOX7/bevacizumab (B) or modified (m)XELOX/bevacizumab with or without erlotinib (E) in first-line metastatic colorectal cancer (MCRC): results of the feasibility phase of the DREAM-OPTIMOX3 study (GERCOR). J Clin Oncol 2007; 25(18 suppl):187s (Abstract 4097).
    • Tournigand C, Lledo G, Delord J, et al. Modified (m)FOLFOX7/bevacizumab (B) or modified (m)XELOX/bevacizumab with or without erlotinib (E) in first-line metastatic colorectal cancer (MCRC): results of the feasibility phase of the DREAM-OPTIMOX3 study (GERCOR). J Clin Oncol 2007; 25(18 suppl):187s (Abstract 4097).
  • 33
    • 34547852270 scopus 로고    scopus 로고
    • Phase II study of FOLFOX, bevacizumab and erlotinib as first-line therapy for patients with metastatic colorectal cancer
    • Meyerhardt JA, Stuart K, Fuchs CS, et al. Phase II study of FOLFOX, bevacizumab and erlotinib as first-line therapy for patients with metastatic colorectal cancer. Ann Oncol 2007; 18:1185-9.
    • (2007) Ann Oncol , vol.18 , pp. 1185-1189
    • Meyerhardt, J.A.1    Stuart, K.2    Fuchs, C.S.3
  • 34
    • 84898690154 scopus 로고    scopus 로고
    • Lacombe DA, Caponigro F, Anthoney A, et al. A phase I study of bortezomib in combination with 5FU/LV plus oxaliplatin in patients (pts) with advanced colorectal cancer (CRC): EORTC 16029. J Clin Oncol 2007; 25(18 suppl):186s (Abstract 4090).
    • Lacombe DA, Caponigro F, Anthoney A, et al. A phase I study of bortezomib in combination with 5FU/LV plus oxaliplatin in patients (pts) with advanced colorectal cancer (CRC): EORTC 16029. J Clin Oncol 2007; 25(18 suppl):186s (Abstract 4090).
  • 35
    • 44449083396 scopus 로고    scopus 로고
    • Phase I/II study of S-1 combined with triweekly irinotecan for advanced or recurrent colorectal cancer
    • 18 suppl):628s Abstract 14541
    • Kakeji Y, Oki E, Yoshida R, et al. Phase I/II study of S-1 combined with triweekly irinotecan for advanced or recurrent colorectal cancer. J Clin Oncol 2007; 25(18 suppl):628s (Abstract 14541).
    • (2007) J Clin Oncol , pp. 25
    • Kakeji, Y.1    Oki, E.2    Yoshida, R.3
  • 36
    • 84898701655 scopus 로고    scopus 로고
    • Cho B, Choi H, Jeung H, et al. Phase II study of oral S-1 monotherapy in metastatic colorectal cancer after failure of both irinotecan and oxaliplatin-containing regimen. J Clin Oncol 2006; 24(18 suppl):170s (Abstract 3597).
    • Cho B, Choi H, Jeung H, et al. Phase II study of oral S-1 monotherapy in metastatic colorectal cancer after failure of both irinotecan and oxaliplatin-containing regimen. J Clin Oncol 2006; 24(18 suppl):170s (Abstract 3597).
  • 37
    • 4344591790 scopus 로고    scopus 로고
    • Adjuvant therapy for stage II colon cancer: A systematic review from the Cancer Care Ontario Program in evidence-based care's gastrointestinal cancer disease site group
    • Figueredo A, Charette ML, Maroun J, et al. Adjuvant therapy for stage II colon cancer: a systematic review from the Cancer Care Ontario Program in evidence-based care's gastrointestinal cancer disease site group. J Clin Oncol 2004; 22:3395-407.
    • (2004) J Clin Oncol , vol.22 , pp. 3395-3407
    • Figueredo, A.1    Charette, M.L.2    Maroun, J.3
  • 38
    • 4344587783 scopus 로고    scopus 로고
    • American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer
    • Benson AB III, Schrag D, Somerfield MR, et al. American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer. J Clin Oncol 2004; 22:3408-19.
    • (2004) J Clin Oncol , vol.22 , pp. 3408-3419
    • Benson III, A.B.1    Schrag, D.2    Somerfield, M.R.3
  • 39
    • 3242657624 scopus 로고    scopus 로고
    • QUASAR: A randomized study of adjuvant chemotherapy (CT) vs observation including 3238 colorectal cancer patients
    • Abstract 3501
    • Gray RG et al. QUASAR: A randomized study of adjuvant chemotherapy (CT) vs observation including 3238 colorectal cancer patients. Proc Am Soc Clin Oncol 2004; 23:246 (Abstract 3501).
    • (2004) Proc Am Soc Clin Oncol , vol.23 , pp. 246
    • Gray, R.G.1
  • 40
    • 84898701554 scopus 로고    scopus 로고
    • Poor outcome in colorectal cancer patients harbouring reduced expression of a multi-gene proliferation signature
    • 18(suppl 7):vii11 Abstract O-002
    • Anjomshoaa A, Lin Y, Black MA, et al. Poor outcome in colorectal cancer patients harbouring reduced expression of a multi-gene proliferation signature. Ann Oncol 2007; 18(suppl 7):vii11 (Abstract O-002).
    • (2007) Ann Oncol
    • Anjomshoaa, A.1    Lin, Y.2    Black, M.A.3
  • 41
    • 84898692126 scopus 로고    scopus 로고
    • Prognosis prediction of stage II colon cancer by gene expression profiling
    • 18(suppl 7):vii22 Abstract O-0037
    • Capella Munar CG, Van Laar R, Moreno Aguardo V, et al. Prognosis prediction of stage II colon cancer by gene expression profiling. Ann Oncol 2007; 18(suppl 7):vii22 (Abstract O-0037).
    • (2007) Ann Oncol
    • Capella Munar, C.G.1    Van Laar, R.2    Moreno Aguardo, V.3
  • 42
    • 34250214962 scopus 로고    scopus 로고
    • Neurotoxicity from oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: NSABP C-07
    • Land SR, Kopec JA, Cecchini RS, et al. Neurotoxicity from oxaliplatin combined with weekly bolus fluorouracil and leucovorin as surgical adjuvant chemotherapy for stage II and III colon cancer: NSABP C-07. J Clin Oncol 2007; 25:2205-11.
    • (2007) J Clin Oncol , vol.25 , pp. 2205-2211
    • Land, S.R.1    Kopec, J.A.2    Cecchini, R.S.3
  • 43
    • 33744831506 scopus 로고    scopus 로고
    • Duration of adjuvant chemotherapy for colon cancer and survival among the elderly
    • Neugut AI, Matasar M, Wang X, et al. Duration of adjuvant chemotherapy for colon cancer and survival among the elderly. J Clin Oncol 2006; 24:2368-75.
    • (2006) J Clin Oncol , vol.24 , pp. 2368-2375
    • Neugut, A.I.1    Matasar, M.2    Wang, X.3
  • 44
    • 20944436646 scopus 로고    scopus 로고
    • A randomised comparison between 6 months of bolus fluorouracil/leucovorin and 12 weeks of protracted venous infusion fluorouracil as adjuvant treatment in colorectal cancer
    • Chau I, Norman AR, Cunningham D, et al. A randomised comparison between 6 months of bolus fluorouracil/leucovorin and 12 weeks of protracted venous infusion fluorouracil as adjuvant treatment in colorectal cancer. Ann Oncol 2005; 16:549-57.
    • (2005) Ann Oncol , vol.16 , pp. 549-557
    • Chau, I.1    Norman, A.R.2    Cunningham, D.3
  • 45
    • 0036176033 scopus 로고    scopus 로고
    • Capecitabine as first-line treatment in colorectal cancer. Pooled data from two large, phase III trials. XELODA Colorectal Cancer Group
    • Twelves C. Capecitabine as first-line treatment in colorectal cancer. Pooled data from two large, phase III trials. XELODA Colorectal Cancer Group. Eur J Cancer 2002; 38(suppl 2):15-20.
    • (2002) Eur J Cancer , vol.38 , Issue.SUPPL. 2 , pp. 15-20
    • Twelves, C.1
  • 46
    • 0036731818 scopus 로고    scopus 로고
    • Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer
    • Douillard JY, Hoff PM, Skillings JR, et al. Multicenter phase III study of uracil/tegafur and oral leucovorin versus fluorouracil and leucovorin in patients with previously untreated metastatic colorectal cancer. J Clin Oncol 2002; 20:3605-16.
    • (2002) J Clin Oncol , vol.20 , pp. 3605-3616
    • Douillard, J.Y.1    Hoff, P.M.2    Skillings, J.R.3
  • 47
    • 84898690223 scopus 로고    scopus 로고
    • Cassidy J, Clarke S, Diaz-Rubio E, et al. XELOX compared to FOLFOX4: survival and response results from XELOX-1/ NO16966, a randomized phase III trial of first-line treatment for patients with metastatic colorectal cancer (MCRC). J Clin Oncol 2007; 25(18 suppl):171s (Abstract 4030).
    • Cassidy J, Clarke S, Diaz-Rubio E, et al. XELOX compared to FOLFOX4: survival and response results from XELOX-1/ NO16966, a randomized phase III trial of first-line treatment for patients with metastatic colorectal cancer (MCRC). J Clin Oncol 2007; 25(18 suppl):171s (Abstract 4030).
  • 48
    • 85031375634 scopus 로고    scopus 로고
    • A randomised phase II study assessing bevacizumab in combination with irinotecan/capecitabine or oxaliplatin/capecitabine as first-line therapy in patients with metastatic colorectal cancer (mCRC): Preliminary results of the AIO study group
    • Presented at: January 19-21, Orlando, FL. Abstract 335
    • Geissler M, Reinacher-Schick A, Freier W, et al. A randomised phase II study assessing bevacizumab in combination with irinotecan/capecitabine or oxaliplatin/capecitabine as first-line therapy in patients with metastatic colorectal cancer (mCRC): preliminary results of the AIO study group. Presented at: 2007 American Society of Clinical Oncology Gastrointestinal Cancers Symposium; January 19-21, 2007; Orlando, FL. Abstract 335.
    • (2007) 2007 American Society of Clinical Oncology Gastrointestinal Cancers Symposium
    • Geissler, M.1    Reinacher-Schick, A.2    Freier, W.3
  • 49
    • 33646443236 scopus 로고    scopus 로고
    • Oral uracil and tegafur plus leucovorin compared with intravenous fluorouracil and leucovorin in stage II and III carcinoma of the colon: Results from National Surgical Adjuvant Breast and Bowel Project protocol C-06
    • Lembersky BC, Wieand HS, Petrelli NJ, et al. Oral uracil and tegafur plus leucovorin compared with intravenous fluorouracil and leucovorin in stage II and III carcinoma of the colon: results from National Surgical Adjuvant Breast and Bowel Project protocol C-06. J Clin Oncol 2006; 24:2059-64.
    • (2006) J Clin Oncol , vol.24 , pp. 2059-2064
    • Lembersky, B.C.1    Wieand, H.S.2    Petrelli, N.J.3
  • 50
    • 33646142547 scopus 로고    scopus 로고
    • Pharmacoeconomic analysis of adjuvant oral capecitabine vs intravenous 5-FU/LV in Dukes' C colon cancer: The X-ACT trial
    • Cassidy J, Douillard JY, Twelves C, et al. Pharmacoeconomic analysis of adjuvant oral capecitabine vs intravenous 5-FU/LV in Dukes' C colon cancer: the X-ACT trial. Br J Cancer 2006; 94:1122-9.
    • (2006) Br J Cancer , vol.94 , pp. 1122-1129
    • Cassidy, J.1    Douillard, J.Y.2    Twelves, C.3
  • 51
    • 34948892072 scopus 로고    scopus 로고
    • Should capecitabine replace infusional fluorouracil and leucovorin when combined with oxaliplatin in metastatic colorectal cancer?
    • Mayer RJ. Should capecitabine replace infusional fluorouracil and leucovorin when combined with oxaliplatin in metastatic colorectal cancer? J Clin Oncol 2007; 25:4165-7.
    • (2007) J Clin Oncol , vol.25 , pp. 4165-4167
    • Mayer, R.J.1
  • 52
    • 33847722573 scopus 로고    scopus 로고
    • Phase III trial of capecitabine plus oxaliplatin as adjuvant therapy for stage III colon cancer: A planned safety analysis in 1,864 patients
    • Schmoll HJ, Cartwright T, Tabernero J, et al. Phase III trial of capecitabine plus oxaliplatin as adjuvant therapy for stage III colon cancer: a planned safety analysis in 1,864 patients. J Clin Oncol 2007; 25:102-9.
    • (2007) J Clin Oncol , vol.25 , pp. 102-109
    • Schmoll, H.J.1    Cartwright, T.2    Tabernero, J.3
  • 53
    • 0035846320 scopus 로고    scopus 로고
    • A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients
    • Sargent DJ, Goldberg RM, Jacobson SD, et al. A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients. N Engl J Med 2001; 345:1091-7.
    • (2001) N Engl J Med , vol.345 , pp. 1091-1097
    • Sargent, D.J.1    Goldberg, R.M.2    Jacobson, S.D.3
  • 54
    • 33847415004 scopus 로고    scopus 로고
    • Toxicities and survival among octogenarians and nonagenarians with colorectal cancer treated with chemotherapy or concurrent chemoradiation therapy
    • Reddy N, Yu J, Fakih MG. Toxicities and survival among octogenarians and nonagenarians with colorectal cancer treated with chemotherapy or concurrent chemoradiation therapy. Clin Colorectal Cancer 2007; 6:362-6.
    • (2007) Clin Colorectal Cancer , vol.6 , pp. 362-366
    • Reddy, N.1    Yu, J.2    Fakih, M.G.3
  • 55
    • 28844482345 scopus 로고    scopus 로고
    • Adjuvant chemotherapy for stage III colon cancer: Implications of race/ethnicity, age, and differentiation
    • Jessup JM, Stewart A, Greene FL, et al. Adjuvant chemotherapy for stage III colon cancer: implications of race/ethnicity, age, and differentiation. JAMA 2005; 294:2703-11.
    • (2005) JAMA , vol.294 , pp. 2703-2711
    • Jessup, J.M.1    Stewart, A.2    Greene, F.L.3
  • 56
    • 0036498881 scopus 로고    scopus 로고
    • Age, sex, and racial differences in the use of standard adjuvant therapy for colorectal cancer
    • Potosky AL, Harlan LC, Kaplan RS, et al. Age, sex, and racial differences in the use of standard adjuvant therapy for colorectal cancer. J Clin Oncol 2002; 20:1192-202.
    • (2002) J Clin Oncol , vol.20 , pp. 1192-1202
    • Potosky, A.L.1    Harlan, L.C.2    Kaplan, R.S.3
  • 57
    • 4444384369 scopus 로고    scopus 로고
    • Implementation of capecitabine (XELODA) into a cancer centre: UK experience
    • Faithfull S, Deery P. Implementation of capecitabine (XELODA) into a cancer centre: UK experience. Eur J Oncol Nurs 2004; 8(suppl 1):S54-62.
    • (2004) Eur J Oncol Nurs , vol.8 , Issue.SUPPL. 1
    • Faithfull, S.1    Deery, P.2
  • 58
    • 15044344552 scopus 로고    scopus 로고
    • Pharmacokinetics in older persons
    • Cusack BJ. Pharmacokinetics in older persons. Am J Geriatr Pharmacother 2004; 2:274-302.
    • (2004) Am J Geriatr Pharmacother , vol.2 , pp. 274-302
    • Cusack, B.J.1
  • 59
    • 0036185589 scopus 로고    scopus 로고
    • Effect of renal impairment on the pharmacokinetics and tolerability of capecitabine (XELODA) in cancer patients
    • Poole C, Gardiner J, Twelves C, et al. Effect of renal impairment on the pharmacokinetics and tolerability of capecitabine (XELODA) in cancer patients. Cancer Chemother Pharmacol 2002; 49:225-34.
    • (2002) Cancer Chemother Pharmacol , vol.49 , pp. 225-234
    • Poole, C.1    Gardiner, J.2    Twelves, C.3
  • 60
    • 1342267612 scopus 로고    scopus 로고
    • Evaluation of the Cockroft-Gault, Jelliffe and Wright formulae in estimating renal function in elderly cancer patients
    • Marx GM, Blake GM, Galani E, et al. Evaluation of the Cockroft-Gault, Jelliffe and Wright formulae in estimating renal function in elderly cancer patients. Ann Oncol 2004; 15:291-5.
    • (2004) Ann Oncol , vol.15 , pp. 291-295
    • Marx, G.M.1    Blake, G.M.2    Galani, E.3
  • 61
    • 34249774066 scopus 로고    scopus 로고
    • Comprehensive geriatric assessment for older patients with cancer
    • Extermann M, Hurria A. Comprehensive geriatric assessment for older patients with cancer. J Clin Oncol 2007; 25:1824-31.
    • (2007) J Clin Oncol , vol.25 , pp. 1824-1831
    • Extermann, M.1    Hurria, A.2
  • 62
    • 2542561964 scopus 로고    scopus 로고
    • Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
    • Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350:2335-42.
    • (2004) N Engl J Med , vol.350 , pp. 2335-2342
    • Hurwitz, H.1    Fehrenbacher, L.2    Novotny, W.3
  • 63
    • 85031386317 scopus 로고    scopus 로고
    • Saltz L, Clarke S, Diaz-Rubio E, et al. Bevacizumab (Bev) in combination with XELOX or FOLFOX4: updated efficacy results from XELOX-1/ NO16966, a randomized phase III trial in first-line metastatic colorectal cancer. J Clin Oncol 2007; 25(18 suppl):170s (Abstract 4028).
    • Saltz L, Clarke S, Diaz-Rubio E, et al. Bevacizumab (Bev) in combination with XELOX or FOLFOX4: updated efficacy results from XELOX-1/ NO16966, a randomized phase III trial in first-line metastatic colorectal cancer. J Clin Oncol 2007; 25(18 suppl):170s (Abstract 4028).
  • 64
    • 84898694023 scopus 로고    scopus 로고
    • Hochster HS, Hart LL, Ramanathan RK, et al. Safety and efficacy of oxaliplatin/fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer (mCRC): final analysis of the TREE-Study. J Clin Oncol 2006; 24(18 suppl):148s (Abstract 3510).
    • Hochster HS, Hart LL, Ramanathan RK, et al. Safety and efficacy of oxaliplatin/fluoropyrimidine regimens with or without bevacizumab as first-line treatment of metastatic colorectal cancer (mCRC): final analysis of the TREE-Study. J Clin Oncol 2006; 24(18 suppl):148s (Abstract 3510).
  • 65
    • 20644432867 scopus 로고    scopus 로고
    • Bevacizumab in combination with fluorouracil and leucovorin: An active regimen for first-line metastatic colorectal cancer
    • Hurwitz HI, Fehrenbacher L, Hainsworth JD, et al. Bevacizumab in combination with fluorouracil and leucovorin: an active regimen for first-line metastatic colorectal cancer. J Clin Oncol 2005; 23:3502-8.
    • (2005) J Clin Oncol , vol.23 , pp. 3502-3508
    • Hurwitz, H.I.1    Fehrenbacher, L.2    Hainsworth, J.D.3
  • 66
    • 85031382204 scopus 로고    scopus 로고
    • Fuchs CS, Marshall J, Mitchell EP, et al. Updated results of BICC-C study comparing first-line irinotecan/fluoropyrimidine combinations with or without celecoxib in mCRC: updated efficacy data. J Clin Oncol 2007; 25(18 suppl):170s (Abstract 4027).
    • Fuchs CS, Marshall J, Mitchell EP, et al. Updated results of BICC-C study comparing first-line irinotecan/fluoropyrimidine combinations with or without celecoxib in mCRC: updated efficacy data. J Clin Oncol 2007; 25(18 suppl):170s (Abstract 4027).
  • 67
    • 21244481589 scopus 로고    scopus 로고
    • High-dose bevacizumab in combination with FOLFOX4 improves survival in patients with previously treated advanced colorectal cancer: Results from the Eastern Cooperative Oncology Group (ECOG) study E3200
    • Presented at: January 27-29, Hollywood, FL. Abstract 169a
    • Giantonio BJ, Catalano PJ, Meropol NJ, et al. High-dose bevacizumab in combination with FOLFOX4 improves survival in patients with previously treated advanced colorectal cancer: results from the Eastern Cooperative Oncology Group (ECOG) study E3200. Presented at: 2005 American Society of Clinical Oncology Gastrointestinal Cancers Symposium; January 27-29, 2005; Hollywood, FL. Abstract 169a.
    • (2005) 2005 American Society of Clinical Oncology Gastrointestinal Cancers Symposium
    • Giantonio, B.J.1    Catalano, P.J.2    Meropol, N.J.3
  • 68
    • 3242720345 scopus 로고    scopus 로고
    • Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer
    • Cunningham D, Humblet Y, Siena S, et al. Cetuximab monotherapy and cetuximab plus irinotecan in irinotecan-refractory metastatic colorectal cancer. N Engl J Med 2004; 351:337-45.
    • (2004) N Engl J Med , vol.351 , pp. 337-345
    • Cunningham, D.1    Humblet, Y.2    Siena, S.3
  • 69
    • 84898698880 scopus 로고    scopus 로고
    • Bokemeyer C, Bondarenko I, Makhson A, et al. Cetuximab plus 5-FU/FA/oxaliplatin (FOLFOX-4) versus FOLFOX-4 in the first-line treatment of metastatic colorectal cancer (mCRC): OPUS, a randomized phase II study. J Clin Oncol 2007; 25(18 suppl): (Abstract 4035).
    • Bokemeyer C, Bondarenko I, Makhson A, et al. Cetuximab plus 5-FU/FA/oxaliplatin (FOLFOX-4) versus FOLFOX-4 in the first-line treatment of metastatic colorectal cancer (mCRC): OPUS, a randomized phase II study. J Clin Oncol 2007; 25(18 suppl): (Abstract 4035).
  • 70
    • 33846100356 scopus 로고    scopus 로고
    • A human colon cancer cell capable of initiating tumour growth in immunodeficient mice
    • O'Brien CA, Pollett A, Gallinger S, et al.A human colon cancer cell capable of initiating tumour growth in immunodeficient mice. Nature 2007; 445:106-10.
    • (2007) Nature , vol.445 , pp. 106-110
    • O'Brien, C.A.1    Pollett, A.2    Gallinger, S.3
  • 71
    • 33646376411 scopus 로고    scopus 로고
    • PTEN dependence distinguishes hematopoietic stem cells from leukemia-initiating cells
    • Yilmaz OH, Valdez R, Theisen BK, et al. PTEN dependence distinguishes hematopoietic stem cells from leukemia-initiating cells. Nature 2006; 441:475-82.
    • (2006) Nature , vol.441 , pp. 475-482
    • Yilmaz, O.H.1    Valdez, R.2    Theisen, B.K.3


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