|
|
Volumn 878, Issue 15-16, 2010, Pages 1169-1177
|
|
Simultaneous determination of tolbutamide, omeprazole, midazolam and dextromethorphan in human plasma by LC-MS/MS-A high throughput approach to evaluate drug-drug interactions
a a a a b b b
a
John)
(United States)
|
|
Author keywords
Dextromethorphan; Drug drug interaction; Incurred sample reproducibility (ISR); LC MS MS; Midazolam; Omeprazole; P450; Tolbutamide
|
|
Indexed keywords
DEXTROMETHORPHAN;
DRUG-DRUG INTERACTIONS;
LC-MS/MS;
MIDAZOLAM;
OMEPRAZOLE;
REPRODUCIBILITIES;
ANESTHETICS;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
LIQUIDS;
MASS SPECTROMETRY;
PHASE SEPARATION;
PLASMA (HUMAN);
PLASMAS;
PROBES;
THROUGHPUT;
DRUG INTERACTIONS;
CYTOCHROME P450 2C19;
CYTOCHROME P450 2C9;
CYTOCHROME P450 2D6;
CYTOCHROME P450 3A4;
DEXTROMETHORPHAN;
GOLD;
MIDAZOLAM;
OMEPRAZOLE;
TOLBUTAMIDE;
ACCURACY;
ADULT;
AREA UNDER THE CURVE;
ARTICLE;
CALIBRATION;
CONTROLLED STUDY;
DRUG BLOOD LEVEL;
DRUG DETERMINATION;
DRUG SAFETY;
DRUG STRUCTURE;
DRUG TOLERABILITY;
ELECTROSPRAY MASS SPECTROMETRY;
HIGH THROUGHPUT SCREENING;
HUMAN;
HUMAN EXPERIMENT;
IN VIVO STUDY;
MALE;
MAXIMUM PLASMA CONCENTRATION;
NORMAL HUMAN;
OPEN STUDY;
PRECIPITATION;
PRIORITY JOURNAL;
QUANTITATIVE ANALYSIS;
REPRODUCIBILITY;
REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
SENSITIVITY AND SPECIFICITY;
SEPARATION TECHNIQUE;
SINGLE DRUG DOSE;
STRUCTURE ANALYSIS;
TANDEM MASS SPECTROMETRY;
VALIDATION PROCESS;
CHROMATOGRAPHY, LIQUID;
CYTOCHROME P-450 ENZYME SYSTEM;
DEXTROMETHORPHAN;
DRUG DISCOVERY;
DRUG INTERACTIONS;
DRUG STABILITY;
HIGH-THROUGHPUT SCREENING ASSAYS;
HUMANS;
MIDAZOLAM;
OMEPRAZOLE;
REPRODUCIBILITY OF RESULTS;
SENSITIVITY AND SPECIFICITY;
TANDEM MASS SPECTROMETRY;
TEMPERATURE;
TOLBUTAMIDE;
|
|
EID: 77950941875
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2010.03.026 Document Type: Article |
|
Times cited : (43)
|
|
References (22)
|
